Title: Holiday Rentals Santa Cruz from £35: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Santa Cruz Travel Guide](https://expedia.co.uk/Santa-Cruz.dx6053940)[Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6053940.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6053940.Holidays-City-Breaks) ![San Lorenzo Cathedral showing a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/115000/115563-Santa-Cruz.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Holiday Rentals in Santa Cruz - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [1 Nov - 2 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-11-01&endDate=2025-11-02&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [2 Nov - 3 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-11-02&endDate=2025-11-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-11-07&endDate=2025-11-09&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-11-14&endDate=2025-11-16&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Holiday Rentals in Santa Cruz ![Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/12ef5e8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/f316b83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/9c72e6dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast (USD 2.40 per person)](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/cbf735a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Suites Deluxe Aparthotel Equipetrol Santa Cruz 9.0/10 Wonderful (77) "Good price, great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Standard Suite, 2 Single Beds | 1 bedroom, hypo-allergenic bedding, down duvets, desk](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/2b6207d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/3e13fa51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | Living area | Printers](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/f61407b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 Queen Bed | Private kitchen | Mini-fridge, microwave, dishwasher, toaster](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/6f15dda8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Equipetrol Suites Apart Hotel Santa Cruz 8.4/10 Very good (7) "Muy bien ubicado, personal amable" ![Spain](https://a.travel-assets.com/egds/marks/flags/es.svg) Roberto Antonio [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) ![House | Pool | Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/16000000/15040000/15030900/15030862/cb1eeefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Vida Santa Cruz 9.0/10 Wonderful (2) "buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa" ![Chile](https://a.travel-assets.com/egds/marks/flags/cl.svg) FERNANDO [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Casa-Vida.h15030862.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/4f23dcbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/2d334027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/0a98f99b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/c0d4ffcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Toborochi Santa Cruz 8.8/10 Excellent (60) "Great pool and rooms, bad service and staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Santiago [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Toborochi.h10031984.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/1f2b7f07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/2d503957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Apartment, 1 Bedroom | Premium bedding, down duvets, in-room safe, laptop workspace](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/4dc82f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/7e27a563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Terranova Suites Santa Cruz 8.0/10 Very good (90) "Easy to access" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dorothy £39 2 Nov - 3 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Terranova-Suites.h10950250.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/edb1b53e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/21992b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/753fda96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/w1290h2293x0y251-5b08e5b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de 2 Habitaciones en zona norte Santa Cruz de la Sierra "Muy buen departamento, bien ubicado" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elva £48 2 Nov - 3 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h119976771.Hotel-Information) ![Business Apartment, Terrace (Plus) | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/e5844260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment, Terrace (Plus) | 1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/bb64c9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/b0eabde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment, Terrace | Private kitchen | Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/cb07702a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Premium Suites Santa Cruz Santa Cruz 8.6/10 Excellent (93) "Everything is perfect!! " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Guillaume [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/e74af5c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment, City View | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/e827de89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Apartment, City View | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/c3714572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/w1125h1500x0y7-eed47d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AMERICA APARTMENTS Santa Cruz £42 3 Nov - 4 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-AMERICA-APARTMENTS.h120442096.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/99089910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/06f19d9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/ada57e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/9c6cc778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Traveler's Hideout Santa Cruz de la Sierra 10/10 Exceptional (1) "The place was cozy, neat, and th host was very attentive and supportive. I recomend this place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mauricio O. £40 2 Nov - 3 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Travelers-Hideout.h100979521.Hotel-Information) ![Microwave, oven, stovetop, electric kettle](https://images.trvl-media.com/lodging/112000000/111970000/111961100/111961080/df3fa641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111970000/111961100/111961080/4e004532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111970000/111961100/111961080/cbb26e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/112000000/111970000/111961100/111961080/ce239bb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Santa Cruz Loft - AC, WiFi, Work Space Santa Cruz £35 3 Nov - 4 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Stylish-Cozy-Studio-With-AC.h111961080.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/89a86d54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/08ad0327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/5c4a14d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, toilet paper](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/80f980e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 2-bedroom apartment with AC, WiFi in enjoyable Santa Cruz Santa Cruz de la Sierra £41 5 Nov - 6 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-2-Bedroom-Apartment-With-AC.h112829576.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/5af8579d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, toilet paper](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/09ebee18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/0f570e73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/7409bf98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartamento confortable para 2 personas Santa Cruz de la Sierra £35 5 Nov - 6 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apartamento-Confortable-Para-2-Personas.h108056147.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/113000000/112230000/112222100/112222028/206167b0_edited_22cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/113000000/112230000/112222100/112222028/32a88bcf_edited_de17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112230000/112222100/112222028/2b580d05_edited_a80f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112230000/112222100/112222028/e59e23c9_edited_fb52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquil apartment with WiFi in Santa Cruz de la Sierra Santa Cruz de la Sierra 10/10 Exceptional (2) "Zona tranquila y todo cerca supermercados tiendas etc" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Fabricio O. £49 10 Nov - 11 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Tranquil-Apartment-With-WiFi-In-Santa-Cruz-De-La-Sierra.h112222028.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/47db859c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/71cea0ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/76d24755.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/3c35b4f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### A must-see studio apartment in Sirari-Equipetrol Santa Cruz de la Sierra £41 3 Nov - 4 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h112789864.Hotel-Information) ![Children’s area](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/81a819db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/8ef87fa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/494b7af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/6191ecc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chalet indept, amplio, acogedor, hermoso jardin Aire C wifi, espa.xcocinar. Santa Cruz de la Sierra £30 2 Nov - 3 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Chalet-Indept.h102550831.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/f31789dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/e1171f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/09d9d05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/13dd729f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Patio Design with private garage Santa Cruz de la Sierra £43 16 Nov - 17 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h112789433.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/00581056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/d52d21aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/c62e4215.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/6a278a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment with balcony, swimming pool, gym, co-work at Equipe Santa Cruz de la Sierra £43 10 Nov - 11 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Modernity-And-Comfort-At-Equipe.h117789345.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/643fec6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/0ab047ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/6b46e3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/bdb54fab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury apartment Santa Cruz de la Sierra £37 2 Nov - 3 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Luxury-Apartment.h117687703.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/97000000/97000000/96998700/96998658/923aa8c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, dishwasher, coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/97000000/97000000/96998700/96998658/w713h1080x604y0-184952e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/97000000/97000000/96998700/96998658/w1614h1080x153y0-bed3a1df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/97000000/97000000/96998700/96998658/w712h1080x604y0-6270880e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### de 6 a 8 Personas Cómodamente Alojadas Santa Cruz de la Sierra 10/10 Exceptional (1) "We enjoyed this apartment. The 4 bedroom and private bathrooms of this unit, work out really well for us. The building has a great security .We were also in a good location. Grocery store was in a walking distance. Junior and Moises were so helpful." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Lucy N. £79 2 Nov - 3 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h96998658.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/6663a26a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/ad376765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, stovetop](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/fa40047b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, stovetop](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/cd3d8ec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC Santa Cruz de la Sierra £36 2 Nov - 3 Nov [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-Studio-In-Enchanting-Santa-Cruz-De-La-Sierra-With-WiFi.h118517530.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16®ionId=6053940&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals) ## Top Santa Cruz Hotel Reviews ![Delfines Collection Hotel By Mercure](//images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/fd3e0846_y.jpg) ### Delfines Collection Hotel By Mercure 10/10 Excellent "Todo excelente como siempre. Merece la pena regresar" [](https://expedia.co.uk/Santa-Cruz-Hotels-Delfines-Collection-Hotel-By-Mercure.h90301892.Hotel-Information) ![Sun Hotel](//images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216_y.jpg) ### Sun Hotel 10/10 Excellent "Great service. " [](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Camino Real Hotel](//images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg) ### Camino Real Hotel 10/10 Excellent "The parrots. Unique" [](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](//images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765_y.jpg) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia 10/10 Excellent "Our room was clean and comfortable. The staff were friendly and very helpful!" [](https://expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](//images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Functional room with direct access to the pool." [](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Chairú Eco Hotel](//images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg) ### Chairú Eco Hotel 10/10 Excellent "Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. " [](https://expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Novotel Santa Cruz De La Sierra](//images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/864143db_y.jpg) ### Novotel Santa Cruz De La Sierra 10/10 Excellent "Fantastic people, very friendly. The hotel was clean, and everything was great. I would pick this hotel anytime. " [](https://expedia.co.uk/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) ![Marriott Santa Cruz de la Sierra Hotel](//images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/a95726cf_y.jpg) ### Marriott Santa Cruz de la Sierra Hotel 10/10 Excellent "Very comfortable " [](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ### Apart Hotel Premium Suites Santa Cruz 10/10 Excellent "Es buena locación , limpio , muy amables" [](https://expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ## Find out more about Santa Cruz **Everything you need to know about** **Santa Cruz** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.  **Santa Cruz holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz holiday rentals we have selected for you start as low as £35 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Santa Cruz rentals** At Expedia, we put the best Santa Cruz holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk - All accommodation types in Santa Cruz ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - [Herefordshire Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Herefordshire.d6046203.Holiday-Rental-Destinations) - [Essex Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Essex.d6046201.Holiday-Rental-Destinations) - [Cumbria Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Cumbria.d6046194.Holiday-Rental-Destinations) - [Yorkshire Holiday Rentals](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals) - [South Wales Holiday Rentals](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals) - [North Wales Holiday Rentals](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals) - [London Holiday Rentals](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals) - [York Holiday Rentals](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals) - [Blackpool Holiday Rentals](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals) - [Isle of Wight Holiday Rentals](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations) - [Scarborough Holiday Rentals](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals) - [Edinburgh Holiday Rentals](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals) - [Bath Holiday Rentals](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals) - [Bournemouth Holiday Rentals](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals) - [England Holiday Rentals](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations) - [Scotland Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations) - [Cornwall Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations) - [Wales Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations) - [Northern Ireland Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations) - [Apartments in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Apartments.d6053940-aaApartments.Travel-Guide-Accommodation) ## Frequently asked questions ### Can I find a holiday rental in Santa Cruz? > Yes, there are holiday rentals in Santa Cruz close to Santa Cruz Zoo, or you can select a more secluded option if you're looking for a relaxing stay. Discover why Santa Cruz is known for its shops. Make sure you have time to check out the cafés and zoo during your trip. ### What are some of the best holiday rentals that Santa Cruz has to offer? > [Casa Vida](https://www.expedia.co.uk/Santa-Cruz-Hotels-Casa-Vida.h15030862.Hotel-Information): This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. Some other top choices in Santa Cruz are [Cozy and independent.Downtown house JH.](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) and [Seasonal House](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h115106104.Hotel-Information). ### How many holiday rentals will I find in Santa Cruz? > With 23 Expedia holiday rentals, you're guaranteed to find just the right place for your Santa Cruz stay. ### What can I see and do in Santa Cruz? > Enjoy the outdoors at Guembe Biocenter and Lomas de Arena Regional Park, or simply take in cultural attractions like Cine Center and Ethno-folkloric Museum. Plaza 24 de Septiembre and Ramon Tahuichi Aguilera Stadium are other places to visit while you're in town. ### What are holiday rentals like in Santa Cruz? > Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santa Cruz. Holiday rentals feature amenities such as kitchens and laundry facilities to help you enjoy your stay. If you're concerned about a clean environment, holiday rentals can provide a sense of privacy away from shared hotel lifts and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular choice for family gatherings. ### Expedia's Latest Trends Hotels - [Hotels near Seven Mile Beach](https://expedia.co.uk/Seven-Mile-Beach-Hotels.0-l6078279-0.Travel-Guide-Filter-Hotels) - [Hotels in Dalyan](https://expedia.co.uk/Dalyan-Hotels.d6047519.Travel-Guide-Hotels) - [Circa 39 Miami Beach](https://expedia.co.uk/Miami-Hotels-Circa-39-Hotel-Miami-Beach.h989148.Hotel-Information) - [The Griffin Inn](https://expedia.co.uk/Brecon-Hotels-The-Griffin-Inn.h42259845.Hotel-Information) - [Hotels in Ripponden](https://expedia.co.uk/Ripponden-Hotels.d6340728.Travel-Guide-Hotels) - [Blique by Nobis, Stockholm, a Member of Design Hotel](https://expedia.co.uk/Stockholm-Hotels-Blique-By-Nobis.h33764650.Hotel-Information) - [Crowne Plaza Seattle - Downtown by IHG](https://expedia.co.uk/Seattle-Hotels-Crowne-Plaza-Seattle-Downtown.h18518.Hotel-Information) - [5 Star Hotels in City of Westminster](https://expedia.co.uk/5Star-City-Of-Westminster-London-Hotels.s50-n179536-0.Travel-Guide-Filter-Hotels) - [Da Vinci's Hotel Derry](https://expedia.co.uk/Londonderry-Hotels-Da-Vincis-Hotel-Derry.h1194529.Hotel-Information) - [Carlton George Hotel](https://expedia.co.uk/Glasgow-Hotels-Carlton-George-Hotel.h574405.Hotel-Information) - [Adults Only Resorts & Hotels in St. Lucia](https://expedia.co.uk/Destinations-In-St-Lucia-Adults-Only-Resorts.0-0-d168-tAdultsOnlyResorts.Hotel-Filter-Destinations) - [Royal & Imperial Belvedere Resort - All inclusive](https://expedia.co.uk/Hersonissos-Hotels-Royal-Imperial-Belvedere-Hotels.h1191451.Hotel-Information) - [The Savoy](https://expedia.co.uk/London-Hotels-The-Savoy.h27158.Hotel-Information) - [Hotels near Eyam Hall](https://expedia.co.uk/Eyam-Hall-Hotels.0-l553248621533024851-0.Travel-Guide-Filter-Hotels) - [Résidence Pierre & Vacances Premium L'Amara](https://expedia.co.uk/Morzine-Hotels-Residence-Pierre-Vacances-Premium-LAmara.h5445898.Hotel-Information) - [Merryl Hotel](https://expedia.co.uk/Paris-Hotels-Hipotel-Paris-Gare-Du-Nord-Merryl.h53552.Hotel-Information) - [Hotels in London](https://expedia.co.uk/London-Hotels.d178279.Travel-Guide-Hotels) - [Hotels in Ackworth](https://expedia.co.uk/Ackworth-Hotels.d3000742356.Travel-Guide-Hotels) - [Hotels in Wembley](https://expedia.co.uk/Wembley-Hotels.d4253.Travel-Guide-Hotels) Flights - [Flights from Norwich (NWI) to Dublin (DUB)](https://expedia.co.uk/lp/flights/nwi/dub/norwich-to-dublin) - [Flights to Kanazawa](https://expedia.co.uk/Cheap-Flights-To-Kanazawa.d9299.Travel-Guide-Flights) - [Flights to Uyuni](https://expedia.co.uk/Cheap-Flights-To-Uyuni.d6139345.Travel-Guide-Flights) - [Flights to Copacabana](https://expedia.co.uk/Cheap-Flights-To-Copacabana.d6048577.Travel-Guide-Flights) - [Flights from Abuja (ABV) to Paisley (GLA)](https://expedia.co.uk/lp/flights/abv/gla/abuja-to-glasgow) - [Flights from Edinburgh (EDI) to Mexico City (MEX)](https://expedia.co.uk/lp/flights/edi/mex/edinburgh-to-mexico-city) - [Flights to Zanzibar](https://expedia.co.uk/Cheap-Flights-To-Zanzibar.d4186.Travel-Guide-Flights) - [Flights from Las Vegas (LAS) to Louisville (SDF)](https://expedia.co.uk/lp/flights/las/sdf/las-vegas-to-louisville) - [Flights from Dublin (DUB) to Charlotte (CLT)](https://expedia.co.uk/lp/flights/dub/clt/dublin-to-charlotte) Packages - [Copacabana Holidays](https://expedia.co.uk/Copacabana.d6048577.Holidays-City-Breaks) - [Planes Holidays](https://expedia.co.uk/Planes.d6202750.Holidays-City-Breaks) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)