Title: Holiday Rentals Santa Cruz from £20: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Santa Cruz Travel Guide](https://expedia.co.uk/Santa-Cruz.dx6053940)[Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6053940.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6053940.Holidays-City-Breaks) ![Santa Cruz](https://images.trvl-media.com/place/6053940/e11e6ae8-6b64-413c-ab96-4d4a810c4d57.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Holiday Rentals in Santa Cruz - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-01-02&endDate=2026-01-04&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-02-13&endDate=2026-02-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz holiday rentals ![Interior](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/494b7af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/2b5f2b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/6649134a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children’s area](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/81a819db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chalet indept, amplio, acogedor, hermoso jardin Aire C wifi, espa.xcocinar. [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Chalet-Indept.h102550831.Hotel-Information) Santa Cruz de la Sierra £29 17 Dec - 18 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Chalet-Indept.h102550831.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/0f570e73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/5af8579d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/2254dc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/7409bf98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartamento confortable para 2 personas [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apartamento-Confortable-Para-2-Personas.h108056147.Hotel-Information) Santa Cruz de la Sierra £34 21 Dec - 22 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apartamento-Confortable-Para-2-Personas.h108056147.Hotel-Information) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111970000/111961100/111961080/f5f74975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111970000/111961100/111961080/4e004532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, electric kettle](https://images.trvl-media.com/lodging/112000000/111970000/111961100/111961080/df3fa641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111970000/111961100/111961080/4ac4de4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Santa Cruz Loft - AC, WiFi, Work Space [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Stylish-Cozy-Studio-With-AC.h111961080.Hotel-Information) Santa Cruz £34 18 Dec - 19 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Stylish-Cozy-Studio-With-AC.h111961080.Hotel-Information) ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/9a481119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment, 2 Bedrooms (Plus) | In-room dining](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/db59d5da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/3d263a1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment, Terrace (Plus) | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/e5844260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Premium Suites Santa Cruz [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) Santa Cruz 8.6/10 Excellent (93) "Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £20 17 Dec - 18 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/b86b5103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/b5037c5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast (USD 2.40 per person)](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/e3b6b11f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Apartment, 1 King Bed with Sofa bed, Terrace | Premium bedding, down duvets, Tempur-Pedic beds, in-room safe](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/3e7101b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Suites Deluxe Aparthotel Equipetrol [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) Santa Cruz 9.0/10 Wonderful (81) "Good price, great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £29 17 Dec - 18 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/47db859c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/21e08eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/71cea0ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/3c35b4f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### A must-see studio apartment in Sirari-Equipetrol [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h112789864.Hotel-Information) Santa Cruz de la Sierra £43 26 Dec - 27 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h112789864.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/5ef98660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/13dd729f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/f31789dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/e1171f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Patio Design with private garage [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h112789433.Hotel-Information) Santa Cruz de la Sierra [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h112789433.Hotel-Information) ![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/9c6cc778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/99089910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/ada57e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/b5dde86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Traveler's Hideout [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Travelers-Hideout.h100979521.Hotel-Information) Santa Cruz de la Sierra 10/10 Exceptional (1) "The place was cozy, neat, and th host was very attentive and supportive. I recomend this place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mauricio O. £40 24 Dec - 25 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Travelers-Hideout.h100979521.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/0ab047ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/bdb54fab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/643fec6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Games room](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/5ceba07c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury apartment [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Luxury-Apartment.h117687703.Hotel-Information) Santa Cruz de la Sierra £37 18 Dec - 19 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Luxury-Apartment.h117687703.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/fdb44263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/080d90c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/w1440h1583x0y0-5b3fde27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/w1440h1927x0y24-b8c75958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dppto Luminoso y Lujoso en Equipe Zona Empresarial [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Dppto-Luminoso-Y-Lujoso-En-Equipe-Zona-Empresarial.h104261770.Hotel-Information) Santa Cruz de la Sierra £52 17 Dec - 18 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Dppto-Luminoso-Y-Lujoso-En-Equipe-Zona-Empresarial.h104261770.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/113000000/112230000/112222100/112222028/206167b0_edited_22cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112230000/112222100/112222028/2b580d05_edited_a80f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/113000000/112230000/112222100/112222028/32a88bcf_edited_de17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/113000000/112230000/112222100/112222028/0c7b09d8_edited_c88f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquil apartment with WiFi in Santa Cruz de la Sierra [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Tranquil-Apartment-With-WiFi-In-Santa-Cruz-De-La-Sierra.h112222028.Hotel-Information) Santa Cruz de la Sierra 10/10 Exceptional (2) "Zona tranquila y todo cerca supermercados tiendas etc" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Fabricio O. £48 13 Jan - 14 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Tranquil-Apartment-With-WiFi-In-Santa-Cruz-De-La-Sierra.h112222028.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/123000000/122870000/122865200/122865145/1b6db924.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/123000000/122870000/122865200/122865145/d11c7efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/123000000/122870000/122865200/122865145/7d62effa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122870000/122865200/122865145/55cf49f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### POX: 24th Floor Green Tower | Luxury and Panoramic View [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h122865145.Hotel-Information) Santa Cruz de la Sierra £65 27 Dec - 28 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h122865145.Hotel-Information) ![House | Pool | Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/16000000/15040000/15030900/15030862/cb1eeefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Vida [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Casa-Vida.h15030862.Hotel-Information) Santa Cruz 9.0/10 Wonderful (2) "buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa" ![Chile](https://a.travel-assets.com/egds/marks/flags/cl.svg) FERNANDO [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Casa-Vida.h15030862.Hotel-Information) ![Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/e2b53d65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/9ccfefc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/3e13fa51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 Queen Bed | Private kitchen | Mini-fridge, microwave, dishwasher, toaster](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/6f15dda8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Equipetrol Suites Apart Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) Santa Cruz 8.4/10 Very good (7) "Perfect hotel" ![Turkey](https://a.travel-assets.com/egds/marks/flags/tr.svg) Yener £28 16 Jan - 17 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/w1290h2293x0y251-5b08e5b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/21992b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/f6e53b9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/f8f1dd6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de 2 Habitaciones en zona norte [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h119976771.Hotel-Information) Santa Cruz de la Sierra "Muy buen departamento, bien ubicado" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elva £47 17 Dec - 18 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h119976771.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/6663a26a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/w1257h960x23y0-1ca3484e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/ad376765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/20029dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-Studio-In-Enchanting-Santa-Cruz-De-La-Sierra-With-WiFi.h118517530.Hotel-Information) Santa Cruz de la Sierra £35 19 Dec - 20 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-Studio-In-Enchanting-Santa-Cruz-De-La-Sierra-With-WiFi.h118517530.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/97000000/97000000/96998700/96998658/923aa8c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, dishwasher, coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/97000000/97000000/96998700/96998658/w713h1080x604y0-184952e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/97000000/97000000/96998700/96998658/w712h1080x604y0-6270880e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/97000000/96998700/96998658/w1613h1080x154y0-2ff2ac20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### de 6 a 8 Personas Cómodamente Alojadas [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h96998658.Hotel-Information) Santa Cruz de la Sierra 10/10 Exceptional (1) "We enjoyed this apartment. The 4 bedroom and private bathrooms of this unit, work out really well for us. The building has a great security .We were also in a good location. Grocery store was in a walking distance. Junior and Moises were so helpful." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Lucy N. £78 17 Dec - 18 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h96998658.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/w689h954x0y0-7d2c5be0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/0169c880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/bde12cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, dishwasher, electric kettle](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/7272b045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy and independent.
Downtown house JH. [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) Santa Cruz de la Sierra £41 17 Dec - 18 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/00581056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/02bc9ba5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/6a278a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/43e6519f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment with balcony, swimming pool, gym, co-work at Equipe [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Modernity-And-Comfort-At-Equipe.h117789345.Hotel-Information) Santa Cruz de la Sierra £54 16 Jan - 17 Jan 2026 [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Modernity-And-Comfort-At-Equipe.h117789345.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/89a86d54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/08ad0327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/5c4a14d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/3e497282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 2-bedroom apartment with AC, WiFi in enjoyable Santa Cruz [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-2-Bedroom-Apartment-With-AC.h112829576.Hotel-Information) Santa Cruz de la Sierra £40 21 Dec - 22 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-2-Bedroom-Apartment-With-AC.h112829576.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-30&endDate=2025-12-31®ionId=6053940&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-19&d2=2026-03-19&lodging=APARTMENT) Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-19&d2=2026-03-19&lodging=APART_HOTEL) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-19&d2=2026-03-19&lodging=VACATION_HOME) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-19&d2=2026-03-19&lodging=CONDO) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-19&d2=2026-03-19&lodging=HOUSE_BOAT) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-19&d2=2026-03-19&lodging=COTTAGE) Chalets [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-19&d2=2026-03-19&lodging=CHALET) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-19&d2=2026-03-19&lodging=CABIN) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals) ## Top Santa Cruz Hotel Reviews ![Hotel LP Santa Cruz Centro](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/60285ad5_y.jpg) ### Hotel LP Santa Cruz Centro 10/10 Excellent "Clean rooms, well kept facilities and nice staff" [](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-LP-Santa-Cruz-Centro.h2761435.Hotel-Information) ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151_y.jpg) ### Ibis Santa Cruz DE LA Sierra 10/10 Excellent "Well kept. Clean, great staff! " [](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Sun Hotel](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216_y.jpg) ### Sun Hotel 10/10 Excellent "spotless" [](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Marriott Santa Cruz de la Sierra Hotel](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/a95726cf_y.jpg) ### Marriott Santa Cruz de la Sierra Hotel 10/10 Excellent "Muy bien exelente" [](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![HOTEL OSHO](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/286f65b1_y.jpg) ### HOTEL OSHO 10/10 Excellent "Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!" [](https://expedia.co.uk/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Everything was absolutely amazing, from the second we arrived to the last day. The service, the room, the property. I always come back to this Hotel time after time. Thank you for all you do to make us feel at home while we’re there " [](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg) ### Camino Real Hotel 10/10 Excellent "Excellent hotel, I willl always used it in this location " [](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Chairú Eco Hotel](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg) ### Chairú Eco Hotel 10/10 Excellent "Clean and close to the malls and restaurants " [](https://expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Lido Hotel](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/da03536f_y.jpg) ### Lido Hotel 10/10 Excellent "The room was clean and comfortable; breakfast was a hot & cold buffet to meet most people’s requirements. It is located a short walk from the main square." [](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Lido.h98237549.Hotel-Information) ## Find out more about Santa Cruz **Everything you need to know about** **Santa Cruz** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Santa Cruz holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Santa Cruz holiday rentals we have selected for you start as low as £20 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Santa Cruz rentals** At Expedia, we put the best Santa Cruz holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk - All accommodation types in Santa Cruz ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold ](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District ](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals ](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - [Herefordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Herefordshire.d6046203.Holiday-Rental-Destinations) - [Essex Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Essex.d6046201.Holiday-Rental-Destinations) - [Cumbria Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cumbria.d6046194.Holiday-Rental-Destinations) - [Yorkshire Holiday Rentals ](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals) - [South Wales Holiday Rentals ](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals) - [North Wales Holiday Rentals ](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals) - [London Holiday Rentals ](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals) - [York Holiday Rentals ](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals) - [Blackpool Holiday Rentals ](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals) - [Isle of Wight Holiday Rentals ](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations) - [Scarborough Holiday Rentals ](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals) - [Edinburgh Holiday Rentals ](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals) - [Bath Holiday Rentals ](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals) - [Bournemouth Holiday Rentals ](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals) - [England Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations) - [Scotland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations) - [Cornwall Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations) - [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations) - [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations) - [Apartments in Santa Cruz ](https://expedia.co.uk/Santa-Cruz-Apartments.d6053940-aaApartments.Travel-Guide-Accommodation) ## Frequently asked questions ### Can I find a holiday rental in Santa Cruz? ### What are some of the best holiday rentals that Santa Cruz has to offer? > Downtown house JH.](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) and [Seasonal House](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h115106104.Hotel-Information). ### How many holiday rentals will I find in Santa Cruz? ### What can I see and do in Santa Cruz? ### What are holiday rentals like in Santa Cruz? ### Expedia's Latest Trends Hotels - [Seven Mile Beach hotels](https://expedia.co.uk/Seven-Mile-Beach-Hotels.0-l6078279-0.Travel-Guide-Filter-Hotels) - [Dalyan Accommodation](https://expedia.co.uk/Dalyan-Hotels.d6047519.Travel-Guide-Hotels) - [Circa 39 Miami Beach](https://expedia.co.uk/Miami-Hotels-Circa-39-Hotel-Miami-Beach.h989148.Hotel-Information) - [The Griffin Inn](https://expedia.co.uk/Brecon-Hotels-The-Griffin-Inn.h42259845.Hotel-Information) - [Ripponden Accommodation](https://expedia.co.uk/Ripponden-Hotels.d6340728.Travel-Guide-Hotels) - [Blique by Nobis, Stockholm, a Member of Design Hotel](https://expedia.co.uk/Stockholm-Hotels-Blique-By-Nobis.h33764650.Hotel-Information) - [Crowne Plaza Seattle - Downtown by IHG](https://expedia.co.uk/Seattle-Hotels-Crowne-Plaza-Seattle-Downtown.h18518.Hotel-Information) - [5 Star Hotels in City of Westminster](https://expedia.co.uk/5Star-City-Of-Westminster-London-Hotels.s50-n179536-0.Travel-Guide-Filter-Hotels) - [Da Vinci's Hotel Derry](https://expedia.co.uk/Londonderry-Hotels-Da-Vincis-Hotel-Derry.h1194529.Hotel-Information) - [Carlton George Hotel](https://expedia.co.uk/Glasgow-Hotels-Carlton-George-Hotel.h574405.Hotel-Information) - [Adults Only Resorts & Hotels in St. Lucia](https://expedia.co.uk/Destinations-In-St-Lucia-Adults-Only-Resorts.0-0-d168-tAdultsOnlyResorts.Hotel-Filter-Destinations) - [Royal & Imperial Belvedere Resort - All inclusive](https://expedia.co.uk/Hersonissos-Hotels-Royal-Imperial-Belvedere-Hotels.h1191451.Hotel-Information) - [The Savoy](https://expedia.co.uk/London-Hotels-The-Savoy.h27158.Hotel-Information) - [Eyam Hall hotels](https://expedia.co.uk/Eyam-Hall-Hotels.0-l553248621533024851-0.Travel-Guide-Filter-Hotels) - [Résidence Pierre & Vacances Premium L'Amara](https://expedia.co.uk/Morzine-Hotels-Residence-Pierre-Vacances-Premium-LAmara.h5445898.Hotel-Information) - [Merryl Hotel](https://expedia.co.uk/Paris-Hotels-Hipotel-Paris-Gare-Du-Nord-Merryl.h53552.Hotel-Information) - [London Accommodation](https://expedia.co.uk/London-Hotels.d178279.Travel-Guide-Hotels) - [Ackworth Accommodation](https://expedia.co.uk/Ackworth-Hotels.d3000742356.Travel-Guide-Hotels) - [Wembley Accommodation](https://expedia.co.uk/Wembley-Hotels.d4253.Travel-Guide-Hotels) Flights - [Flights from Norwich to Dublin](https://expedia.co.uk/lp/flights/nwi/dub/norwich-to-dublin) - [Flights to Kanazawa](https://expedia.co.uk/Cheap-Flights-To-Kanazawa.d9299.Travel-Guide-Flights) - [Flights to Uyuni](https://expedia.co.uk/Cheap-Flights-To-Uyuni.d6139345.Travel-Guide-Flights) - [Flights to Copacabana](https://expedia.co.uk/Cheap-Flights-To-Copacabana.d6048577.Travel-Guide-Flights) - [Flights from Abuja to Glasgow](https://expedia.co.uk/lp/flights/abv/gla/abuja-to-glasgow) - [Flights from Edinburgh to Mexico City](https://expedia.co.uk/lp/flights/edi/mex/edinburgh-to-mexico-city) - [Flights to Zanzibar](https://expedia.co.uk/Cheap-Flights-To-Zanzibar.d4186.Travel-Guide-Flights) - [Flights from Las Vegas to Louisville](https://expedia.co.uk/lp/flights/las/sdf/las-vegas-to-louisville) - [Flights from Dublin to Charlotte](https://expedia.co.uk/lp/flights/dub/clt/dublin-to-charlotte) Packages - [Copacabana Holidays](https://expedia.co.uk/Copacabana.d6048577.Holidays-City-Breaks) - [Planes Holidays](https://expedia.co.uk/Planes.d6202750.Holidays-City-Breaks) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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