Title: Holiday Rentals Santa Cruz from £20: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Santa Cruz Hotels](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations)[Santa Cruz Flights](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations)[Santa Cruz Car Hire](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Car-Hire-Destinations)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6297178.Holidays-City-Breaks) ![San Lorenzo Cathedral featuring heritage elements, heritage architecture and a church or cathedral](https://images.trvl-media.com/place/6098830/d6a325c3-d504-4e1a-ab2b-0e430beefd40.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6098830/d6a325c3-d504-4e1a-ab2b-0e430beefd40.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Santa Cruz Accommodation: Most Popular Cities to Stay ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Santa Cruz [](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals) ![Mountain view in Samaipata, Florida Province of the Santa Cruz Department, Bolivia](https://images.trvl-media.com/place/6200976/99855abd-1497-49bc-91a5-ef76c4e902cb.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Samaipata [](https://expedia.co.uk/Samaipata-Holiday-Rentals.d6200976.Travel-Guide-HolidayRentals) ![Portrait of a Tobas warrior during carnival called The Devil Dance (La Diablada), Oruro, Bolivia](https://images.trvl-media.com/place/6352296/feec42f5-cbd9-4576-97cc-129e51391796.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Warnes [](https://expedia.co.uk/Warnes-Holiday-Rentals.d6352296.Travel-Guide-HolidayRentals) ## Our top choices for Santa Cruz holiday rentals ![Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/e2b53d65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/3e13fa51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/9ccfefc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 Queen Bed | Private kitchen | Mini-fridge, microwave, dishwasher, toaster](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/e1ac9300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Equipetrol Suites Apart Hotel [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) Santa Cruz 8.8/10 Excellent (9 reviews) "Perfect hotel" ![Turkey](https://a.travel-assets.com/egds/marks/flags/tr.svg) Yener [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/b86b5103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast (USD 2.40 per person)](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/e3b6b11f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/b5037c5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/0144c46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Suites Deluxe Aparthotel Equipetrol [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) Santa Cruz 9.0/10 Wonderful (82 reviews) "Good price, great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £28 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/7e27a563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, microwave, electric kettle, cookware/dishes/utensils](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/6fc90c50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/47df2d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/1f2b7f07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Terranova Suites [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Terranova-Suites.h10950250.Hotel-Information) Santa Cruz 8.0/10 Very good (90 reviews) "Easy to access" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dorothy £34 2 Mar - 3 Mar [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Terranova-Suites.h10950250.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/83c0e879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/2d334027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/912c7493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/c0d4ffcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Toborochi [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Toborochi.h10031984.Hotel-Information) Santa Cruz 8.8/10 Excellent (60 reviews) "Very comfortable and quiet place and very good location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Toborochi.h10031984.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103790000/103788400/103788309/b3756d0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103790000/103788400/103788309/894e0ecb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103790000/103788400/103788309/130e8dcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103790000/103788400/103788309/aa4340a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Samaipata Glamping [](https://www.expedia.co.uk/Samaipata-Hotels-Samaipata-Glaming.h103788309.Hotel-Information) Samaipata £167 1 Feb - 2 Feb [](https://www.expedia.co.uk/Samaipata-Hotels-Samaipata-Glaming.h103788309.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/0f570e73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/2254dc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/5af8579d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/7409bf98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartamento confortable para 2 personas [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apartamento-Confortable-Para-2-Personas.h108056147.Hotel-Information) Santa Cruz de la Sierra £33 3 Feb - 4 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apartamento-Confortable-Para-2-Personas.h108056147.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/89a86d54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/08ad0327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, toilet paper](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/80f980e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112830000/112829600/112829576/3e497282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 2-bedroom apartment with AC, WiFi in enjoyable Santa Cruz [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-2-Bedroom-Apartment-With-AC.h112829576.Hotel-Information) Santa Cruz de la Sierra £39 3 Feb - 4 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-2-Bedroom-Apartment-With-AC.h112829576.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/w1125h1510x0y0-a0234ee9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/w1125h1500x0y7-eed47d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Apartment, City View | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/c3714572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment, City View | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120450000/120442100/120442096/1c1dec0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AMERICA APARTMENTS [](https://www.expedia.co.uk/Santa-Cruz-Hotels-AMERICA-APARTMENTS.h120442096.Hotel-Information) Santa Cruz £40 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-AMERICA-APARTMENTS.h120442096.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/w1290h2293x0y251-5b08e5b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/f8f1dd6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/21992b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/f6e53b9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de 2 Habitaciones en zona norte [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h119976771.Hotel-Information) Santa Cruz de la Sierra "Muy buen departamento, bien ubicado" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elva £46 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h119976771.Hotel-Information) ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/9a481119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/3d263a1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment, 2 Bedrooms (Plus) | In-room dining](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/db59d5da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment, Terrace (Plus) | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/e5844260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Premium Suites Santa Cruz [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) Santa Cruz 8.6/10 Excellent (98 reviews) "Yes, staff were very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) veronica £20 10 Feb - 11 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/0ab047ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/df4a9290.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Games room](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/5ceba07c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/118000000/117690000/117687800/117687703/643fec6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury apartment [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Luxury-Apartment.h117687703.Hotel-Information) Santa Cruz de la Sierra £35 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Luxury-Apartment.h117687703.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/fdb44263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/w1440h1049x0y0-23015e62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/080d90c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104270000/104261800/104261770/w1440h1927x0y24-b8c75958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dppto Luminoso y Lujoso en Equipe Zona Empresarial [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Dppto-Luminoso-Y-Lujoso-En-Equipe-Zona-Empresarial.h104261770.Hotel-Information) Santa Cruz de la Sierra £50 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Dppto-Luminoso-Y-Lujoso-En-Equipe-Zona-Empresarial.h104261770.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/123000000/122870000/122865200/122865145/1b6db924.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/123000000/122870000/122865200/122865145/7d62effa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/123000000/122870000/122865200/122865145/d11c7efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122870000/122865200/122865145/55cf49f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### POX: 24th Floor Green Tower | Luxury and Panoramic View [](https://www.expedia.co.uk/Santa-Cruz-Hotels-POX-24th-Floor-Green-Tower-Luxury-And-Panoramic-View.h122865145.Hotel-Information) Santa Cruz de la Sierra £63 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-POX-24th-Floor-Green-Tower-Luxury-And-Panoramic-View.h122865145.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/494b7af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children’s area](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/81a819db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/2b5f2b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102560000/102550900/102550831/6649134a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chalet indept, amplio, acogedor, hermoso jardin Aire C wifi, espa.xcocinar. [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Chalet-Indept.h102550831.Hotel-Information) Santa Cruz de la Sierra £28 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Chalet-Indept.h102550831.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/w689h954x0y0-7d2c5be0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/af1568a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/bde12cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/0169c880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy and independent.
Downtown house JH. [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) Santa Cruz de la Sierra £40 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) ![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/9c6cc778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/b5dde86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/99089910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, electric kettle, blender](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/27ac2eed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Traveler's Hideout [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Travelers-Hideout.h100979521.Hotel-Information) Santa Cruz de la Sierra 10/10 Exceptional (1 review) "The place was cozy, neat, and th host was very attentive and supportive. I recomend this place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mauricio O. £38 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Travelers-Hideout.h100979521.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/101000000/100290000/100284400/100284354/6d55bdca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/101000000/100290000/100284400/100284354/d7013903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/101000000/100290000/100284400/100284354/43ed5064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/101000000/100290000/100284400/100284354/1c0d3586.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO! [](https://www.expedia.co.uk/Santa-Cruz-Hotels-COMODO-MONOAMBIENTE-EN-EQUIPETROL-CON-PISCINA-EN-CONDOMINIO.h100284354.Hotel-Information) Santa Cruz de la Sierra £51 31 Jan - 1 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-COMODO-MONOAMBIENTE-EN-EQUIPETROL-CON-PISCINA-EN-CONDOMINIO.h100284354.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/40000000/39200000/39191300/39191276/b0b12908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living room | 42-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/40000000/39200000/39191300/39191276/e3241ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children’s activities](https://images.trvl-media.com/lodging/40000000/39200000/39191300/39191276/7ea6ea10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/40000000/39200000/39191300/39191276/5afb2720.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Santos Apartamentos [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Santos-Apartamentos.h39191276.Hotel-Information) Santa Cruz £106 5 Feb - 6 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Santos-Apartamentos.h39191276.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/6663a26a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/w1257h960x23y0-1ca3484e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/ad376765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/f8c2e918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-Studio-In-Enchanting-Santa-Cruz-De-La-Sierra-With-WiFi.h118517530.Hotel-Information) Santa Cruz de la Sierra £37 1 Feb - 2 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-Studio-In-Enchanting-Santa-Cruz-De-La-Sierra-With-WiFi.h118517530.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/00581056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/43e6519f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/6a278a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117790000/117789400/117789345/2ccfeb55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment with balcony, swimming pool, gym, co-work at Equipe [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Modernity-And-Comfort-At-Equipe.h117789345.Hotel-Information) Santa Cruz de la Sierra £43 9 Feb - 10 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Modernity-And-Comfort-At-Equipe.h117789345.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-13&endDate=2026-02-14®ionId=6297178&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=APART_HOTEL) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=APARTMENT) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=CONDO) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=VACATION_HOME) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=COTTAGE) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=HOUSE_BOAT) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=CABIN) Chalets [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Bolivia®ionId=6297178&latLong=-17.783494%2C-63.182085&adults=2&startDate=2026-04-29&d1=2026-04-29&endDate=2026-05-02&d2=2026-05-02&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Holiday-Rental-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Holiday-Rental-Destinations) ## Top Santa Cruz Hotel Reviews ![HOTEL OSHO](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/286f65b1_y.jpg) ### HOTEL OSHO 10/10 Excellent "The room is always beautifully kept, and Hilary at the front desk is so attentive. Looking forward to the breakfast as it is amazing. John" [](https://expedia.co.uk/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) ![Sun Hotel](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216_y.jpg) ### Sun Hotel 10/10 Excellent "I appreciate the reliability of the Sun Hotel’s shuttle service whisking you from the airport to a comfortable room after a long day’s travel. The breakfast the next morning, some time in the fitness room and a swim in the pool was everything I needed to be ready to continue my trip." [](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg) ### Camino Real Hotel 10/10 Excellent "Rooms were very clean and service was excellent " [](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![TRYP by Wyndham Santa Cruz](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/78f237b9_y.jpg) ### TRYP by Wyndham Santa Cruz 10/10 Excellent "Yes! Room was spotless. The staff are very patient and professional. " [](https://expedia.co.uk/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Indeed this is a First Class hotel. Beautiful lobby, great dining area, beautiful pool, ample rooms. " [](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Lido Hotel](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/da03536f_y.jpg) ### Lido Hotel 10/10 Excellent "We stayed at the fabulous Lido Hotel for 2 nights in December 2025\. The hotel is located in central Santa Cruz, within a 4 block walk from Plaza 24 de Septiembre, and also a short 10 minute walk from the iconic Cristo Redentor statue. Check in was quick and painless, and the front desk staff was friendly and helpful. The room itself was spacious, clean and comfortable, with a large attached full bathroom. The air conditioner did a great job of cooling the room. Breakfast was served each morning in the attached Chinese restaurant, and featured eggs, breakfast meats, fruits, juices, cereal and yogurt, and was a great way to fuel up before venturing out to explore Santa Cruz. Without equivocation, I highly recommend the Lido Hotel to anyone in search of a clean comfortable hotel at an affordable price in the enchanting metrolopolis of Santa Cruz de la Sierra, Bolivia. Dr. Kingstone Shih and Laura Meneses Los Altos, California USA " [](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Lido.h98237549.Hotel-Information) ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151_y.jpg) ### Ibis Santa Cruz DE LA Sierra 10/10 Excellent "Amazing breakfast " [](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765_y.jpg) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia 10/10 Excellent "Maria in front desk was extremely helpful . Especially since we did not know the language and we checked in too late. She was kidn to arrange a taxi for us to get some fruits for dinner from supermarket. Maria is extremely responsive and was supportive throughout my entire stay. Thank you maria" [](https://expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Chairú Eco Hotel](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg) ### Chairú Eco Hotel 10/10 Excellent "Clean room and friendly staff " [](https://expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ## Find out more about Santa Cruz **Everything you need to know about** **Santa Cruz** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. **Santa Cruz holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Santa Cruz holiday rentals we have selected for you start as low as £20 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Santa Cruz rentals** At Expedia, we put the best Santa Cruz holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Popular Santa Cruz Cities - [Santa Cruz Holiday Rentals ](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals) - [Samaipata Holiday Rentals ](https://expedia.co.uk/Samaipata-Holiday-Rentals.d6200976.Travel-Guide-HolidayRentals) - [Warnes Holiday Rentals ](https://expedia.co.uk/Warnes-Holiday-Rentals.d6352296.Travel-Guide-HolidayRentals) ### Expedia's Latest Trends Hotels - [Galápagos Accommodation](https://expedia.co.uk/Destinations-In-Galapagos.d1371.Hotel-Destinations) - [All-Inclusive Hotels in Rio de Janeiro State](https://expedia.co.uk/Destinations-In-Rio-De-Janeiro-State-All-Inclusive-Hotel.0-0-d6052641-tAllInclusiveHotel.Hotel-Filter-Destinations) Flights - [Cheap Flights to São Paulo State](https://expedia.co.uk/Destinations-In-Sao-Paulo-State.d6052648.Flight-Destinations) - [Cheap Flights to Florida](https://expedia.co.uk/Destinations-In-Florida.d6278083.Flight-Destinations) - [Cheap Flights to Tierra del Fuego Province](https://expedia.co.uk/Destinations-In-Tierra-Del-Fuego-Province.d6208785.Flight-Destinations) - [Cheap Flights to Galápagos](https://expedia.co.uk/Destinations-In-Galapagos.d1371.Flight-Destinations) - [Cheap Flights to Bahia State](https://expedia.co.uk/Destinations-In-Bahia-State.d6052623.Flight-Destinations) - [Flights to SRZ](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights) - [Cheap Flights to Cusco Region](https://expedia.co.uk/Destinations-In-Cusco-Region.d6235224.Flight-Destinations) - [Cheap Flights to Rio de Janeiro State](https://expedia.co.uk/Destinations-In-Rio-De-Janeiro-State.d6052641.Flight-Destinations) Activities - [Things to do in Rio de Janeiro State](https://expedia.co.uk/Things-To-Do-In-Rio-De-Janeiro-State.d6052641.Travel-Guide-Activities) Packages - [Florida City Breaks](https://expedia.co.uk/Florida.d6278083.Holidays-City-Breaks) - [Bahia State City Breaks](https://expedia.co.uk/Bahia-State.d6052623.Holidays-City-Breaks) - [Santa Catarina City Breaks](https://expedia.co.uk/Santa-Catarina.d6052646.Holidays-City-Breaks) - [Alagoas City Breaks](https://expedia.co.uk/Alagoas.d6052620.Holidays-City-Breaks) - [Warnes City Breaks](https://expedia.co.uk/Warnes.d6352296.Holidays-City-Breaks) - [Galápagos City Breaks](https://expedia.co.uk/Galapagos.d1371.Holidays-City-Breaks) General - [Visit La Paz](https://expedia.co.uk/La-Paz.dx6297090) - [Visit Potosi](https://expedia.co.uk/Potosi.dx6297171) - [Visit Catamarca Province](https://expedia.co.uk/Catamarca-Province.dx6232516) - [Visit Santa Cruz](https://expedia.co.uk/Santa-Cruz.dx6053940) - [Visit La Pampa Province](https://expedia.co.uk/La-Pampa-Province.dx6232299) - [Visit Morona Santiago](https://expedia.co.uk/Morona-Santiago.dx6239604) - [Visit Jujuy Province](https://expedia.co.uk/Jujuy-Province.dx6232492) - [Visit Santa Fe Province](https://expedia.co.uk/Santa-Fe-Province.dx6232320) - [Visit Paraná](https://expedia.co.uk/Parana.dx6052638) - [Visit Mato Grosso do Sul](https://expedia.co.uk/Mato-Grosso-Do-Sul.dx6052631) - [Visit Magallanes y Antartica Chilena](https://expedia.co.uk/Magallanes-Y-Antartica-Chilena.dx6236290) - [Visit Santa Catarina](https://expedia.co.uk/Santa-Catarina.dx6052646) - [Visit Rio Grande do Sul](https://expedia.co.uk/Rio-Grande-Do-Sul.dx6052643)