Title: Holiday Rentals Santa Cruz from £32: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Santa Cruz Hotels](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations)[Santa Cruz Flights](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations)[Santa Cruz Car Hire](https://expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Car-Hire-Destinations)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6297178.Holidays-City-Breaks) ![Lake Titicaca featuring general coastal views and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/240000/240645-Lake-Titicaca.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Holiday Rentals in Santa Cruz ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Santa Cruz Accommodation: Most Popular Cities to Stay ![San Lorenzo Cathedral showing a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/115000/115563-Santa-Cruz.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Santa Cruz [](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals) ![](https://mediaim.expedia.com/destination/2/06496d3cec9b6cad4a738ddeb6156d1c.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Samaipata [](https://expedia.co.uk/Samaipata-Holiday-Rentals.d6200976.Travel-Guide-HolidayRentals) ## Top Holiday Rentals in Santa Cruz ## Our top choices for Santa Cruz holiday rentals ![Business Apartment, Terrace (Plus) | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/e5844260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment, Terrace (Plus) | 1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/bb64c9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment, Terrace | Private kitchen | Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/cb07702a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/b0eabde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Premium Suites Santa Cruz Santa Cruz 8.6/10 Excellent (92) "Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. " [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/12ef5e8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Apartment, 1 King Bed with Sofa bed, Terrace | 2 bedrooms, premium bedding, down duvets, Tempur-Pedic beds](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/72a81d70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast (USD 2.40 per person)](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/cbf735a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/9c72e6dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Suites Deluxe Aparthotel Equipetrol Santa Cruz 9.0/10 Wonderful (74) "Good price, great hotel!" [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Standard Suite, 2 Single Beds | 1 bedroom, hypo-allergenic bedding, down duvets, desk](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/2b6207d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | Living area | Printers](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/f61407b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | Private kitchen | Mini-fridge, microwave, dishwasher, toaster](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/c6295e62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 Queen Bed | Private kitchen | Mini-fridge, microwave, dishwasher, toaster](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/6f15dda8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Equipetrol Suites Apart Hotel Santa Cruz 8.4/10 Very good (7) "Perfect hotel" [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/1f2b7f07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/7e27a563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Twin Room | Premium bedding, down duvets, in-room safe, laptop workspace](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/0202a8df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Apartment, 1 Bedroom | Premium bedding, down duvets, in-room safe, laptop workspace](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/4dc82f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Terranova Suites Santa Cruz 8.0/10 Very good (90) "The pictures of the property have to be from a decade ago. This place it is dirty and in poor shape. " £32 18 Sept - 19 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Terranova-Suites.h10950250.Hotel-Information) ![House | Pool | Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/16000000/15040000/15030900/15030862/cb1eeefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Vida Santa Cruz 9.0/10 Wonderful (2) "buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa" [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Casa-Vida.h15030862.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/4f23dcbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/912c7493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/0a98f99b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/2d334027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Toborochi Santa Cruz 8.8/10 Excellent (60) "Property is close to nice dining options and entertainment places in Santa Cruz. The room is confortable and spacious " [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apart-Hotel-Toborochi.h10031984.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/106000000/105470000/105461200/105461150/3d2a0753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge](https://images.trvl-media.com/lodging/106000000/105470000/105461200/105461150/4e8a585d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105470000/105461200/105461150/3cc3c9f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/106000000/105470000/105461200/105461150/088b7732.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Montefuego Samaipata Samaipata [](https://www.expedia.co.uk/Samaipata-Hotels-Montefuego-Samaipata.h105461150.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/f31789dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/09d9d05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/13dd729f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/113000000/112790000/112789500/112789433/6fa8d2d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Patio Design with private garage Santa Cruz de la Sierra [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h112789433.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/5af8579d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, toilet paper](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/09ebee18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/7409bf98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108060000/108056200/108056147/f2893bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartamento confortable para 2 personas Santa Cruz de la Sierra £34 19 Sept - 20 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apartamento-Confortable-Para-2-Personas.h108056147.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/6663a26a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, stovetop](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/cd3d8ec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, stovetop](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/fa40047b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/119000000/118520000/118517600/118517530/20029dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC Santa Cruz de la Sierra £33 29 Sept - 30 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Cozy-Studio-In-Enchanting-Santa-Cruz-De-La-Sierra-With-WiFi.h118517530.Hotel-Information) ![Standard Suite, 1 Queen Bed, Accessible | Living room | 40-inch flat-screen TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/21000000/20400000/20394100/20394083/323847b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Frette Italian sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/21000000/20400000/20394100/20394083/16d0b602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/21000000/20400000/20394100/20394083/40d15c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/21000000/20400000/20394100/20394083/3e7b8ee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Suites Apart Hotel Santa Cruz 8.4/10 Very good (37) "Exelente & New closest to the city modern nice view to the city " [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Urban-Suites-Apart-Hotel.h20394083.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/99089910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, electric kettle, blender](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/272f7d30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/ada57e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/101000000/100980000/100979600/100979521/9c6cc778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Traveler's Hideout Santa Cruz de la Sierra 10/10 Exceptional (1) "The place was cozy, neat, and th host was very attentive and supportive. I recomend this place" £39 16 Sept - 17 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Travelers-Hideout.h100979521.Hotel-Information) ![Apartment, 1 Bedroom, Accessible, Smoking | Exterior](https://images.trvl-media.com/lodging/106000000/105900000/105899800/105899783/cf1d467f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Accessible, Smoking | Interior](https://images.trvl-media.com/lodging/106000000/105900000/105899800/105899783/167fc0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Accessible, Smoking | View from property](https://images.trvl-media.com/lodging/106000000/105900000/105899800/105899783/65b83b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Accessible, Smoking | Lounge](https://images.trvl-media.com/lodging/106000000/105900000/105899800/105899783/w2046h1360x2y3-cf85833e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buena Vista Rental House Santa Cruz [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Buena-Vista-Rental-House.h105899783.Hotel-Information) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/115000000/114480000/114470600/114470519/3f55b9d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114480000/114470600/114470519/04594ed8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114480000/114470600/114470519/3ec4aead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/115000000/114480000/114470600/114470519/063d6efb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed Santa Cruz de la Sierra 10/10 Exceptional (1) £39 16 Sept - 17 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Luxury-And-Comfort-At-Equipetrol.h114470519.Hotel-Information) ![Design Cabin, 1 Bedroom, Balcony, Mountain View | Terrace/patio](https://images.trvl-media.com/lodging/104000000/103790000/103788400/103788309/3d1d2cc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103790000/103788400/103788309/894e0ecb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Cabin, Balcony, Mountain View | In-room safe, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103790000/103788400/103788309/3652f4c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/104000000/103790000/103788400/103788309/ae705635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Samaipata Glamping Samaipata £151 21 Sept - 22 Sept [](https://www.expedia.co.uk/Samaipata-Hotels-Samaipata-Glaming.h103788309.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/edb1b53e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/f8f1dd6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/w1290h2293x0y251-5b08e5b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/120000000/119980000/119976800/119976771/753fda96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de 2 Habitaciones en zona norte Santa Cruz de la Sierra £46 16 Sept - 17 Sept [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h119976771.Hotel-Information) ![Basic Apartment, 3 Bedrooms | Living area | TV](https://images.trvl-media.com/lodging/109000000/108440000/108438700/108438680/a62553a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108440000/108438700/108438680/05181a1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, Balcony, City View | 2 bedrooms, soundproofing](https://images.trvl-media.com/lodging/109000000/108440000/108438700/108438680/01e1f934.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/109000000/108440000/108438700/108438680/12996667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartamentos ARTECI Santa Cruz [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Apartamentos-ARTECI.h108438680.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/47db859c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/7576825b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/76d24755.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/113000000/112790000/112789900/112789864/71cea0ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### A must-see studio apartment in Sirari-Equipetrol Santa Cruz de la Sierra [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h112789864.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/112000000/111740000/111734600/111734526/53688531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/112000000/111740000/111734600/111734526/bda32973.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/112000000/111740000/111734600/111734526/aaae0a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111740000/111734600/111734526/7e38476c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### "Modern 2-bedroom apartment in an exclusive building in Santa Cruz, Bolivia." Santa Cruz de la Sierra [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Modern-2-Bedroom-Apartment-In-An-Exclusive-Building-In-Santa-Cruz.h111734526.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/43000000/42240000/42232700/42232614/b28f0fc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42240000/42232700/42232614/f8d40c7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, blender, cookware/dishes/utensils](https://images.trvl-media.com/lodging/43000000/42240000/42232700/42232614/6b903d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/43000000/42240000/42232700/42232614/d0da0eac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Espacio seguro, tranquilo, relajado y placentero. Santa Cruz de la Sierra 10/10 Exceptional (1) "If you are looking for a great place to stay while in Santa Cruz Bolivia this is the place." [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Espacio-Seguro.h42232614.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-09-29&endDate=2025-09-30®ionId=6297178&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Holiday-Rental-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Holiday-Rental-Destinations) ## Top Santa Cruz Hotel Reviews ![Marriott Santa Cruz de la Sierra Hotel](//images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/a95726cf_y.jpg) ### Marriott Santa Cruz de la Sierra Hotel 10/10 Excellent "Nice" [](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](//images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Los Tajibos is perhaps the best place to stay in Santa Cruz." [](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Sun Hotel](//images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216_y.jpg) ### Sun Hotel 10/10 Excellent "Friendly and staff very cooperative." [](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Camino Real Hotel](//images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg) ### Camino Real Hotel 10/10 Excellent "Very comfortable, great location. My favorite in Santa Cruz. Big enough / small enough" [](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Delfines Collection Hotel By Mercure](//images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/a3164128_edited_3199_y.jpg) ### Delfines Collection Hotel By Mercure 10/10 Excellent "Clean comfortable rooms " [](https://expedia.co.uk/Santa-Cruz-Hotels-Delfines-Collection-Hotel-By-Mercure.h90301892.Hotel-Information) ![TRYP by Wyndham Santa Cruz](//images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/78f237b9_y.jpg) ### TRYP by Wyndham Santa Cruz 10/10 Excellent "I suggest more fruits for breakfast , very limited options , king staff" [](https://expedia.co.uk/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ![Chairú Eco Hotel](//images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg) ### Chairú Eco Hotel 10/10 Excellent "Like clean close to the city and malls are " [](https://expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](//images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765_y.jpg) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia 10/10 Excellent "Everything thanks " [](https://expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Ibis Santa Cruz DE LA Sierra](//images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/640c92ef_y.jpg) ### Ibis Santa Cruz DE LA Sierra 10/10 Excellent "The " [](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ## Find out more about Santa Cruz **Everything you need to know about** **Santa Cruz** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search.  **Santa Cruz holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz holiday rentals we have selected for you start as low as £32 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Santa Cruz rentals** At Expedia, we put the best Santa Cruz holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Popular Santa Cruz Cities - [Santa Cruz Holiday Rentals](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals) - [Samaipata Holiday Rentals](https://expedia.co.uk/Samaipata-Holiday-Rentals.d6200976.Travel-Guide-HolidayRentals) - [Warnes Holiday Rentals](https://expedia.co.uk/Warnes-Holiday-Rentals.d6352296.Travel-Guide-HolidayRentals) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)