Title: TOP Luxury Hotels in Santa Cruz for 2025 - Santa Cruz Upscale Hotels | Expedia.co.uk [Santa Cruz Travel Guide](https://expedia.co.uk/Santa-Cruz.dx6053940)[Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6053940.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6053940.Holidays-City-Breaks) ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Santa Cruz - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Luxury Hotels Tonight [26 Nov - 27 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-11-26&endDate=2025-11-27&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [27 Nov - 28 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-11-27&endDate=2025-11-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-11-28&endDate=2025-11-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Santa Cruz Luxury Hotels ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/c96e3d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 Double Bed | Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/d249effb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/9bf66d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel Santa Cruz 9.0/10 Wonderful (343) "Accommodating staff, comfortable rooms, wonderful pool" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jay £97 15 Dec - 16 Dec [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11®ionId=6053940&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_BF_PROMO_6053940) ## Find out more about Santa Cruz ### Santa Cruzand its attractions for luxury travelers Santa Cruz, Bolivia, offers a blend of luxury and adventure that is perfect for discerning travellers. Begin your journey at the stunning Biocentro Güembé, a lavish tropical park where you can relax in a high-end spa or stroll through beautifully landscaped gardens filled with exotic wildlife. Next, explore the vibrant Mercado Los Pozos, where you can delight in an array of local crafts and flavours, perhaps picking up some unique Bolivian souvenirs. For a taste of culture, visit the impressive Museo de Arte Contemporáneo, showcasing contemporary works that reflect the country's rich heritage. Spend an afternoon at the exclusive Equipetrol neighbourhood, known for its upscale dining and boutique shops, providing a perfect backdrop for a leisurely lunch or an evening of fine dining. Finally, don't miss the chance to unwind at the Parque El Arenal, a serene oasis in the city where you can enjoy a leisurely stroll or a picnic with your family. When it comes to accommodation, luxury hotels in the Equipetrol area offer elegant rooms and exceptional service, ensuring you feel pampered during your stay. From fine dining options to personalised concierge services, these hotels create a perfect launchpad for your Santa Cruz adventures. ### Find the best luxury hotels and resorts in Santa Cruz For discerning travellers seeking a lavish getaway in Santa Cruz, these hotels offer unparalleled luxury and comfort, ensuring a memorable stay. [Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) - **Why it's great for a luxury retreat:** Los Tajibos impresses luxury travellers with its refined ambiance and a solid guest review rating of 9.0. Highlights include a 24-hour restaurant, a rejuvenating spa with hydrotherapy treatments, and plush premium bedding, ensuring a restful retreat. Guests can unwind in the hot tub or enjoy the elegance of room service that operates around the clock. - **Other amenities:** Additional features include a terrace for evening relaxation, a fitness centre for those wishing to maintain their routine, and complimentary buffet breakfast. The hotel also offers exclusive spa treatments such as body wraps and scrubs, along with convenient airport shuttles, making it a haven for luxury and comfort. - **Nearby attractions:** Santa Cruz Zoo - 1.4 km, Patio Design LifeStyle Center - 1.4 km, Ventura Mall - 2.3 km [Marriott Santa Cruz de la Sierra Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) - **Why it's great for a luxury retreat:** Marriott Santa Cruz de la Sierra presents a luxurious retreat with an exceptional guest review rating of 9.0. Guests can revel in the comfort of executive rooms, complete with access to a private lounge, and experience the indulgence of in-room dining through 24-hour room service. The hotel also features onsite tennis facilities for those looking to stay active during their stay. - **Other amenities:** Beyond its luxury amenities, the hotel offers a beautiful rooftop garden terrace for relaxation and an outdoor pool with sun loungers. Guests can enjoy the convenience of onsite massage treatments and a full-service spa. With accessible fitness facilities and generous parking options, this hotel is designed to meet the needs of luxury travellers seeking both comfort and style. - **Nearby attractions:** Santa Cruz Zoo - 2.4 km, Patio Design LifeStyle Center - 1.9 km, Ventura Mall - 0.7 km [Camino Real Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) - **Why it's great for a luxury retreat:** Camino Real Hotel stands out as a premier choice for luxury seekers, an impressive guest review rating of 8.8. Guests are treated to a wealth of high-end amenities, including a stunning outdoor pool with a swim-up bar, a tranquil spa offering massage treatments, and a restaurant with beautiful garden views. The 24-hour room service and concierge ensure that every need is catered to in style. - **Other amenities:** In addition to its luxurious offerings, the hotel features an art gallery on-site, perfect for those looking to indulge in culture during their stay. Guests can enjoy a poolside bar, a wellness centre with sauna and hydromassage options, and free buffet breakfast daily. With a shopping district nearby, guests can enjoy both relaxation and retail therapy while enjoying the spacious terrace for unwinding after a day of exploration. - **Nearby attractions:** Santa Cruz Zoo - 2 km, Patio Design LifeStyle Center - 2.2 km, Ventura Mall - 0.8 km [Sun Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) - **Why it's great for a luxury retreat:** Sun Hotel offers a delightful blend of luxury and comfort, reflected in its guest review rating of 8.2. The hotel features a 24-hour room service option and designer toiletries in every room, providing guests with a touch of elegance. The inviting outdoor pool and hot tub create a perfect setting for relaxation after a day of exploring Santa Cruz. - **Other amenities:** Additional amenities include a terrace for enjoying the pleasant Bolivian climate, a buffet breakfast served daily, and various spa treatments such as reflexology and body treatments. Guests can also take advantage of the airport shuttle service, ensuring a seamless travel experience. The hotel’s arcade game room adds a playful touch to the luxury experience, ideal for unwinding in style. - **Nearby attractions:** Play Land Amusement Park - 2.6 km, Univalle - 8.8 km ## Top Santa Cruz Hotel Reviews ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Accommodating staff, comfortable rooms, wonderful pool" [](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ## Frequently asked questions ### What are the top-rated luxury hotels in Santa Cruz? > Among the top-rated luxury hotels in Santa Cruz, Novotel Santa Cruz De La Sierra, [Marriott Santa Cruz de la Sierra Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information), and [Swissôtel Santa Cruz De La Sierra](https://www.expedia.co.uk/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) are consistently celebrated for their exceptional quality. > > > > The 5-star Novotel Santa Cruz De La Sierra, with a 9.2 rating, is located within a shopping district and offers premium bedding and rainfall showerheads. Reviewers frequently praise the comfortable pillows and excellent restaurant. > > > > The 5-star Marriott Santa Cruz de la Sierra Hotel, rated 9.0, provides executive rooms with lounge access and on-site tennis facilities. Customers consistently highlight the great service. > > > > The 4.5-star Swissôtel Santa Cruz De La Sierra, with a 9.2 rating, features a poolside bar and premium bedding. Its facilities are frequently described as excellent, with a great location and good showers. ### Which area of Santa Cruz is best to stay in for luxury hotels? > The best area to stay in Santa Cruz for luxury hotels is Equipetrol, particularly around the avenues San Martín and Las Américas. > > > > Equipetrol is known for its modern infrastructure and upscale amenities, making it the city's most exclusive district. It's characterised by wide, tree-lined streets, contemporary high-rise buildings, and a wide array of high-end shopping centres, gourmet restaurants, and sophisticated nightlife options. It's a well-maintained area that feels quite distinct from the more traditional city centre. > > > > For couples seeking a refined and comfortable stay, Equipetrol is an excellent choice. The area offers numerous luxury hotels with amenities such as rooftop pools, fine dining restaurants, and high-end fitness equipment. It's superb for those who appreciate convenience and quality, with many establishments providing excellent service and a tranquil environment away from the city's busiest parts. > > > > Business travellers will also find Equipetrol highly suitable. Many corporate offices are located within or close to the district, and the hotels often feature extensive business facilities, including conference rooms and executive lounges. ### How much does a luxury hotel in Santa Cruz cost? > Luxury hotel prices in Santa Cruz vary, but you can find a great deal from £97 on Expedia. To find the best prices on luxury stays, be flexible with your dates—typically, off-peak and mid-week stays are cheaper. Sort your search results by "Price: low to high" to see our lowest rates. ### Which luxury hotels in Santa Cruz are good for families? > For families seeking luxury accommodation in Santa Cruz, Novotel Santa Cruz De La Sierra, [Marriott Santa Cruz de la Sierra Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information), and [Camino Real Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) offer excellent amenities and services. > > > > The 5-star Novotel Santa Cruz De La Sierra, with a 9.2 rating, provides 24-hour room service and premium bedding, ensuring comfort for all family members. Its location within a shopping district is also convenient. > > > > The Marriott Santa Cruz de la Sierra Hotel, also 5-star with a 9.0 rating, offers spacious suites and an executive lounge, providing ample space and exclusive services for families. On-site tennis facilities can also be a valuable amenity. > > > > The 4.5-star Camino Real Hotel, rated 8.8, features a garden-view restaurant and a poolside bar, suitable for family dining and relaxation. Reviewers frequently praise its excellent location and super helpful staff. ### What are the best luxury hotels in Santa Cruz with a pool? > For luxury hotels in Santa Cruz offering excellent pool facilities, consider the Novotel Santa Cruz De La Sierra, the [Marriott Santa Cruz de la Sierra Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information), and the [Swissôtel Santa Cruz De La Sierra](https://www.expedia.co.uk/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information). > > > > The 5-star Novotel Santa Cruz De La Sierra, with a 9.2 rating, provides both outdoor and children's pools, making it suitable for families. Guests frequently praise the comfortable pillows and excellent restaurant. > > > > The 5-star Marriott Santa Cruz de la Sierra Hotel, rated 9.0, features an outdoor pool. Customers consistently highlight the great service. > > > > The 4.5-star Swissôtel Santa Cruz De La Sierra, also with a 9.2 rating, offers an outdoor pool and a poolside bar. Reviewers often praise the excellent facilities and great location. ### Are there any top luxury hotels near Ventura Mall? > For travellers seeking top luxury hotels near Ventura Mall in Santa Cruz, Bolivia, the [Camino Real Hotel](https://www.expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) and the [Swissôtel Santa Cruz De La Sierra](https://www.expedia.co.uk/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) are excellent considerations. > > > > The 4.5-star Camino Real Hotel, with an 8.8 rating, is known for its excellent location, which places guests within a shopping district. Reviewers frequently praise the exceptionally helpful and kind staff. The hotel also features an on-site art gallery, a swim-up bar, and a restaurant with garden views. > > > > The 4.5-star Swissôtel Santa Cruz De La Sierra, boasting a 9.2 rating, is also conveniently located. Guests consistently highlight the excellent facilities and comfortable bedding, with specific mentions of good beds and showers. The hotel offers a poolside bar and 24-hour room service. ### What luxury activities and experiences are there in Santa Cruz? > The best area to stay in Santa Cruz for luxury experiences is Equipetrol, known for its modern amenities and upscale offerings. > > > > Equipetrol is a contemporary district characterised by wide avenues, new high-rise buildings, and a generally polished appearance. It's located just north of the city centre, making it easily accessible while feeling distinct. You'll find many of the city's finest hotels, gourmet restaurants, and exclusive boutiques along its main streets, particularly around Avenida San Martín. > > > > For couples seeking a sophisticated escape, Equipetrol offers numerous opportunities for high-end dining, from innovative international cuisine to refined local dishes. Many hotels in this area feature rooftop pools and bars, great for enjoying the city views. The neighbourhood also has several upscale shopping centres, such as Ventura Mall, where you can find designer brands and specialty shops. > > > > Travellers looking for premium wellness and relaxation will find Equipetrol particularly appealing. Many luxury hotels here provide comprehensive spa services, including massages and beauty treatments. ### How can I save on a luxury hotel in Santa Cruz with Expedia? > There are plenty of ways to save on a luxury hotel in Santa Cruz. Join [One Key™](https://www.expedia.co.uk/welcome-one-key), our free travel rewards programme, to unlock Member Prices across a range of hotels. Typically, booking in advance will help you save on hotel bookings. If you're feeling spontaneous, be sure to check for last-minute deals. ### Is it cheaper to book a luxury Santa Cruz hotel and flights as a package? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect [travel package](https://www.expedia.co.uk/Santa-Cruz.d6053940.Holidays-City-Breaks). ### Can I cancel my luxury hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. 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[Flights from Copiapo (CPO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/cpo/srz/copiapo-to-santa-cruz) - [Flights from Dhahran (DHA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/dha/srz/dhahran-to-santa-cruz) - [Flights from The Dalles (DLS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/dls/srz/the-dalles-to-santa-cruz) - [Flights from Derby (DRB) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/drb/srz/derby-to-santa-cruz) - [Flights from Dublin (DUB) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/dub/srz/dublin-to-santa-cruz) - [Flights from Dubai (DXB) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/dxb/srz/dubai-to-santa-cruz) - [Flights from Buenos Aires (EZE) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/eze/vvi/buenos-aires-to-santa-cruz) - [Flights from Flores (FRS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/frs/srz/flores-to-santa-cruz) - [Flights from Gaya (GAY) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/gay/srz/gaya-to-santa-cruz) - [Flights from Rio de Janeiro (GIG) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/gig/srz/rio-de-janeiro-to-santa-cruz) - [Flights from Isla Baltra (GPS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/gps/srz/isla-baltra-to-santa-cruz) - [Flights from São Paulo (GRU) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/gru/vvi/sao-paulo-to-santa-cruz) - [Flights from Gatokae (GTA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/gta/srz/gatokae-to-santa-cruz) - [Flights from Guayaquil (GYE) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/gye/vvi/guayaquil-to-santa-cruz) - [Flights from Freetown (HGS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/hgs/srz/freetown-to-santa-cruz) - [Flights from Frankfurt (HHN) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/hhn/srz/frankfurt-to-santa-cruz) - [Flights from Khajuraho (HJR) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/hjr/srz/khajuraho-to-santa-cruz) - [Flights from Takaka (KTF) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/ktf/srz/takaka-to-santa-cruz) - [Flights from Las Vegas (LAS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/las/srz/las-vegas-to-santa-cruz) - [Flights from Los Angeles (LAX) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/lax/vvi/los-angeles-to-santa-cruz) - [Flights from London (LGW) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/lgw/vvi/london-to-santa-cruz) - [Flights from London (LHR) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/lhr/srz/london-to-santa-cruz) - [Flights from London (LHR) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/lhr/vvi/london-to-santa-cruz) - [Flights from Lima (LIM) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/lim/vvi/lima-to-santa-cruz) - [Flights from Ljubljana (LJU) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/lju/srz/ljubljana-to-santa-cruz) - [Flights from London (LON) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/lon/vvi/london-to-santa-cruz) - [Flights from La Paz (LPB) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/lpb/vvi/la-paz-to-santa-cruz) - [Flights from Madrid (MAD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/mad/srz/madrid-to-santa-cruz) - [Flights from Madrid (MAD) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/mad/vvi/madrid-to-santa-cruz) - [Flights from Manchester (MAN) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/man/vvi/manchester-to-santa-cruz) - [Flights from Orlando (MCO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/mco/srz/orlando-to-santa-cruz) - [Flights from Managua (MGA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/mga/srz/managua-to-santa-cruz) - [Flights from Nuremberg (NUE) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/nue/srz/nuremberg-to-santa-cruz) - [Flights from Oakland (ODM) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/odm/srz/oakland-to-santa-cruz) - [Flights from Orlando (ORL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/orl/srz/orlando-to-santa-cruz) - [Flights from Panama City (PAC) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/pac/srz/panama-city-to-santa-cruz) - [Flights from Punta Islita (PBP) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/pbp/srz/punta-islita-to-santa-cruz) - [Flights from Potosi (POI) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/poi/srz/potosi-to-santa-cruz) - [Flights from Panama City (PTY) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/pty/srz/panama-city-to-santa-cruz) - [Flights from Puerto Vallarta (PVR) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/pvr/srz/puerto-vallarta-to-santa-cruz) - [Flights from Dallas (RBD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/rbd/srz/dallas-to-santa-cruz) - [Flights from Resende (REZ) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/rez/srz/resende-to-santa-cruz) - [Flights from Riberalta (RIB) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/rib/srz/riberalta-to-santa-cruz) - [Flights from San Diego (SAN) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/san/srz/san-diego-to-santa-cruz) - [Flights from Santa Ana del Yacuma (SBL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sbl/srz/santa-ana-del-yacuma-to-santa-cruz) - [Flights from Stockton (SCK) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sck/srz/stockton-to-santa-cruz) - [Flights from Santiago (SCL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/scl/srz/santiago-to-santa-cruz) - [Flights from San Francisco (SFO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sfo/srz/san-francisco-to-santa-cruz) - [Flights from San Francisco (SFO) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/sfo/vvi/san-francisco-to-santa-cruz) - [Flights from Springfield (SGF) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sgf/srz/springfield-to-santa-cruz) - [Flights from San Juan (SJU) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sju/srz/san-juan-to-santa-cruz) - [Flights from Salt Lake City (SLC) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/slc/srz/salt-lake-city-to-santa-cruz) - [Flights from Santa Maria (SMX) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/smx/srz/santa-maria-to-santa-cruz) - [Flights from Alcantarí Intl. Airport (SRE) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sre/srz/sucre-to-santa-cruz) - [Flights from Sydney (SYD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/syd/srz/sydney-to-santa-cruz) - [Flights from Trinidad (TDD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tdd/srz/trinidad-to-santa-cruz) - [Flights from Tarija (TJA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tja/srz/tarija-to-santa-cruz) - [Flights from Tsushima (TSJ) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tsj/srz/tsushima-to-santa-cruz) - [Flights from Lake Tahoe (TVL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tvl/srz/lake-tahoe-to-santa-cruz) - [Flights from Ulaangom (ULO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/ulo/srz/ulaangom-to-santa-cruz) - [Flights from Upolu Point (UPP) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/upp/srz/upolu-point-to-santa-cruz) - [Flights from Uyuni (UYU) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/uyu/vvi/uyuni-to-santa-cruz) - [Flights from Veracruz (VER) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/ver/srz/veracruz-to-santa-cruz) - [Flights from Van Nuys (VNY) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/vny/srz/van-nuys-to-santa-cruz) - [Flights from Mayo (YMA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/yma/srz/mayo-to-santa-cruz) - [Visit Colinas del Urubo](https://www.expedia.co.uk/Colinas-Del-Urubo.dx6349680) - [Ethno-Folkloric Museum](https://www.expedia.co.uk/Ethno-Folkloric-Museum-Santa-Cruz.d6098834.Attraction)