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£275 Cheap Flights from Guayaquil (GYE) to Santa Cruz (VVI)

View £275 flight on Tue, 9 Mar 2027Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Santa Cruz (VVI-Viru Viru Intl.)

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Cheap Flights from Guayaquil (GYE) to Santa Cruz (VVI)

Prices were available within the past 7 days and start at £275 for one-way flights and £546 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Tue, 9 Mar - Sun, 14 Mar
GYE
Guayaquil
VVI
Santa Cruz
£546 Return, found 6 days ago
£546
Return
found 6 days ago
Select avianca flight, departing Tue, 9 Mar from Guayaquil to Santa Cruz, returning Sun, 14 Mar, priced at £546 found 6 days ago
Copa
Tue, 15 Dec - Thu, 7 Jan
GYE
Guayaquil
VVI
Santa Cruz
£609 Return, found 6 days ago
£609
Return
found 6 days ago
Select Copa flight, departing Tue, 15 Dec from Guayaquil to Santa Cruz, returning Thu, 7 Jan, priced at £609 found 6 days ago
Copa
Tue, 9 Mar - Sun, 14 Mar
GYE
Guayaquil
VVI
Santa Cruz
£611 Return, found 6 days ago
£611
Return
found 6 days ago
Select Copa flight, departing Tue, 9 Mar from Guayaquil to Santa Cruz, returning Sun, 14 Mar, priced at £611 found 6 days ago
Copa
Tue, 9 Mar - Sun, 14 Mar
GYE
Guayaquil
VVI
Santa Cruz
£620 Return, found 6 days ago
£620
Return
found 6 days ago
Select Copa flight, departing Tue, 9 Mar from Guayaquil to Santa Cruz, returning Sun, 14 Mar, priced at £620 found 6 days ago
Copa
Tue, 9 Mar - Sun, 14 Mar
GYE
Guayaquil
VVI
Santa Cruz
£635 Return, found 6 days ago
£635
Return
found 6 days ago
Select Copa flight, departing Tue, 9 Mar from Guayaquil to Santa Cruz, returning Sun, 14 Mar, priced at £635 found 6 days ago
avianca
Tue, 9 Mar - Sun, 14 Mar
GYE
Guayaquil
VVI
Santa Cruz
£638 Return, found 6 days ago
£638
Return
found 6 days ago
Select avianca flight, departing Tue, 9 Mar from Guayaquil to Santa Cruz, returning Sun, 14 Mar, priced at £638 found 6 days ago
Copa
Tue, 9 Mar - Sun, 14 Mar
GYE
Guayaquil
VVI
Santa Cruz
£644 Return, found 6 days ago
£644
Return
found 6 days ago
Select Copa flight, departing Tue, 9 Mar from Guayaquil to Santa Cruz, returning Sun, 14 Mar, priced at £644 found 6 days ago
Copa
Tue, 15 Dec - Thu, 7 Jan
GYE
Guayaquil
VVI
Santa Cruz
£646 Return, found 6 days ago
£646
Return
found 6 days ago
Select Copa flight, departing Tue, 15 Dec from Guayaquil to Santa Cruz, returning Thu, 7 Jan, priced at £646 found 6 days ago
avianca
Tue, 9 Mar - Sun, 14 Mar
GYE
Guayaquil
VVI
Santa Cruz
£655 Return, found 6 days ago
£655
Return
found 6 days ago
Select avianca flight, departing Tue, 9 Mar from Guayaquil to Santa Cruz, returning Sun, 14 Mar, priced at £655 found 6 days ago
avianca
Tue, 9 Mar - Sun, 14 Mar
GYE
Guayaquil
VVI
Santa Cruz
£657 Return, found 6 days ago
£657
Return
found 6 days ago
Select avianca flight, departing Tue, 9 Mar from Guayaquil to Santa Cruz, returning Sun, 14 Mar, priced at £657 found 6 days ago

Frequently asked questions

How much does a flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) cost?
You can find one-way and return flights from GYE to VVI with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when GYE to VVI ticket fares go up or down.
What is the cheapest month to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
The cheapest months to fly from GYE to VVI are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
Enter GYE to VVI and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
LATAM Airlines Group is one of the cheapest airlines offering connecting return flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.), with a layover in Mariscal Sucre Intl. (UIO), with tickets starting from around £604 for flights that can be booked for departure within the next year. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
To find a cheap flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
There are approximately 11 connecting flights per day from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.). Some common connection points include Tocumen Intl. (PTY), El Dorado Intl. (BOG), and Mariscal Sucre Intl. (UIO).
What is the earliest flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
The earliest flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) typically departs around 3:30 AM local time. This flight is operated by Avianca. This is a seasonal service active in January, February, March, November, and December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
You'll generally find the most flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) on a Tuesday, with around 13 flights available. This gives you a good selection of options for your journey. Major airlines on this route include Copa, LATAM Airlines Group, and Avianca. Flight schedules are fairly consistent throughout the week, so you'll have several flight options no matter which day you choose to fly.
What are the most popular departure times for flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
The most popular departure times for flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) are in the evening, from 6pm to 9pm. Many major carriers, including LATAM Airlines Group and Copa, offer flights during this window. This timing works well because you can make the most of your day before your evening flight.
How long does it take to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
There are no nonstop flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.). For flights with one stop, you can expect the journey to take around 15 hours 22 minutes. If your flight has two or more stops, the travel time will be a bit longer, typically around 16 hours 25 minutes. This route covers a distance of approximately 2,512 kilometers. Keep in mind that actual flight times can vary due to factors like layover duration, routing, and weather conditions.
Can you fly business or first class from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
Yes, you can fly business class between Guayaquil (GYE) and Santa Cruz (VVI).You can fly business class with Copa and Avianca.
How do I earn miles on a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) flight with Expedia?
It's easy to earn miles on a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santa Cruz (VVI) from Guayaquil (GYE)?
If you're planning to travel to Santa Cruz from Jose Joaquin de Olmedo Intl. (GYE), you can fly directly into Viru Viru Intl. (VVI). Some flights may connect through major hubs like Mariscal Sucre Intl. (UIO) before reaching Santa Cruz. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) at the last minute?
Typically, booking a last minute flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) flight and hotel package?
Securing a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.)?
If you booked your Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santa Cruz (VVI-Viru Viru Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Viru Viru Intl.
Return price
£545
Distance
2497 km

Book with confidence

Compare flights from Guayaquil to Santa Cruz easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Guayaquil to Santa Cruz. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Viru Viru Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Jose Joaquin de Olmedo Intl. to Viru Viru Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Jose Joaquin de Olmedo Intl. (GYE) to Viru Viru Intl. (VVI)

The easiest way to view the best deals on flights from Guayaquil to Santa Cruz today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Jose Joaquin de Olmedo Intl. to Viru Viru Intl. start at just £546 and range up to £657.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Guayaquil and Santa Cruz
  • booking your flight during March, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Guayaquil to Santa Cruz flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Jose Joaquin de Olmedo Intl. to Viru Viru Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Guayaquil to Santa Cruz easily and book with confidence

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