Title: TOP Boutique Hotels in Santa Cruz for 2025 | Expedia.co.uk [Santa Cruz Travel Guide](https://expedia.co.uk/Santa-Cruz.dx6053940)[Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6053940.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6053940.Holidays-City-Breaks) ![Santa Cruz featuring a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/115000/115559-Santa-Cruz.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in Santa Cruz ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Boutique Hotels Tonight [26 Sept - 27 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-09-26&endDate=2025-09-27&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-09-27&endDate=2025-09-28&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-09-26&endDate=2025-09-28&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Cruz Boutique Hotels ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/5000000/4560000/4555100/4555047/28071027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Down duvets, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/5000000/4560000/4555100/4555047/52d9469b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Down duvets, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/5000000/4560000/4555100/4555047/dde52746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds | Down duvets, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/5000000/4560000/4555100/4555047/e572106a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Senses Boutique Hotel Santa Cruz 8.0/10 Very good (287) "Very large and confortable rooms in central location. Breakfast could be better but staff is very friendly and helpful " [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Senses-Boutique-Hotel.h4555047.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11®ionId=6053940&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Cruz Hotel Reviews ## Frequently asked questions ### What's there to see and do in Santa Cruz? > The shopping is one thing to enjoy while you're in the area. Activities and attractions to experience around Santa Cruz include Plaza 24 de Septiembre, Ramon Tahuichi Aguilera Stadium and Cine Center. You might also like to explore more of the area and take in additional sights like Santa Cruz Zoo, Ventura Mall and Guembe Biocenter while you're here. ### What kind of weather should I plan for when I travel to Santa Cruz? > Understanding the weather in Santa Cruz will help you enjoy your stay to the fullest. The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm. ### What's the best way to get to my boutique hotel in Santa Cruz? > You have a few options for travelling to and around Santa Cruz. The closest major airport is Santa Cruz (VVI-Viru Viru Intl.), which is located 9.8 mi (15.8 km) from the heart of the city. To venture out into the surrounding area, take a train from Santa Cruz de la Sierra Station. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - [5 Star Hotels in Colinas del Urubo](https://www.expedia.co.uk/5Star-Colinas-Del-Urubo-Hotels.s50-0-d6349680.Travel-Guide-Filter-Hotels) - [Colinas del Urubo Hotels](https://www.expedia.co.uk/Colinas-Del-Urubo-Hotels.d6349680.Travel-Guide-Hotels) - [Santa Cruz Hotels](https://www.expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations) - [Spa Hotels in Warnes](https://www.expedia.co.uk/Warnes-Hotels-Spa-Hotels.0-0-d6352296-tSpaHotels.Travel-Guide-Filter-Hotels) - [Flights to El Trompillo](https://www.expedia.co.uk/Cheap-Flights-To-El-Trompillo.d6032083.Travel-Guide-Flights) - [Flights to Santa Cruz](https://www.expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations) - [Flights from El Trompillo](https://www.expedia.co.uk/lp/airports/srz/flights-from-el-trompillo-airport) - [Flights from Viru Viru Intl.](https://www.expedia.co.uk/lp/airports/vvi/flights-from-viru-viru-intl-airport) - 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[Flights from Alcantarí Intl. Airport (SRE) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sre/srz/sucre-to-santa-cruz) - [Flights from Sydney (SYD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/syd/srz/sydney-to-santa-cruz) - [Flights from Trinidad (TDD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tdd/srz/trinidad-to-santa-cruz) - [Flights from Tarija (TJA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tja/srz/tarija-to-santa-cruz) - [Flights from Tsushima (TSJ) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tsj/srz/tsushima-to-santa-cruz) - [Flights from Lake Tahoe (TVL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tvl/srz/lake-tahoe-to-santa-cruz) - [Flights from Ulaangom (ULO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/ulo/srz/ulaangom-to-santa-cruz) - [Flights from Upolu Point (UPP) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/upp/srz/upolu-point-to-santa-cruz) - [Flights from Uyuni (UYU) to Santa Cruz (VVI)](https://www.expedia.co.uk/lp/flights/uyu/vvi/uyuni-to-santa-cruz) - [Flights from Veracruz (VER) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/ver/srz/veracruz-to-santa-cruz) - [Flights from Van Nuys (VNY) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/vny/srz/van-nuys-to-santa-cruz) - [Flights from Mayo (YMA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/yma/srz/mayo-to-santa-cruz) - [Visit Colinas del Urubo](https://www.expedia.co.uk/Colinas-Del-Urubo.dx6349680) - [Ethno-Folkloric Museum](https://www.expedia.co.uk/Ethno-Folkloric-Museum-Santa-Cruz.d6098834.Attraction)