Title: Hotels in Upstate South Carolina - Best Upstate South Carolina Hotels from £52 - Fully Refundable Options - Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix # Find hotels in Upstate South Carolina, SC from £52 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Upstate South Carolina Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=SPA_ON_SITE) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=PETS) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=CABIN) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=APARTMENT) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=HOT_TUB) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=CONDO) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&amenities=POOL) Villa [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=VILLA) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&travelerType=family_friendly) Farm [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=AGRITOURISM) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2025-12-28&d1=2025-12-28&endDate=2025-12-30&d2=2025-12-30&lodging=COTTAGE) ## Check prices for these dates Tonight [14 Dec - 15 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [15 Dec - 16 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina hotels ![Meeting facility](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/cbe6a617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e408dd97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.co.uk/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (557) Located within a 15-minute drive of Clemson University and Lake Keowee, this hotel offers convenient amenities including free WiFi and parking. Enjoy drinks at the bar or meals at the on-site restaurant while staying near Sloan Tennis Centre and Littlejohn Coliseum. --- "location is amazing! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) colleen [](https://www.expedia.co.uk/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/3000000/2990000/2983200/2983181/w3996h2667x0y0-e59088f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2990000/2983200/2983181/0741038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2990000/2983200/2983181/ef4e166d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2990000/2983200/2983181/w4000h2664x0y0-3026bfef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Marriott Clemson [](https://www.expedia.co.uk/Anderson-Hotels-Courtyard-Marriott-Clemson.h2983181.Hotel-Information) Clemson 9.0/10 Wonderful (523) Located just a 5-minute drive from Clemson University, this hotel offers an outdoor pool and American cuisine at The Bistro. Guests can unwind at the bar, work out in the fitness centre, and enjoy free WiFi and parking while exploring nearby attractions. --- "Great property " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shaun £89 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Courtyard-Marriott-Clemson.h2983181.Hotel-Information) ![Two queen beds nonsmoking | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/65554714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/c13da5b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/f21c3602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast ](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/c7944b9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Easley [](https://www.expedia.co.uk/Easley-Hotels-Hampton-Inn-Easley.h1453465.Hotel-Information) Easley 9.4/10 Exceptional (681) Enjoy a refreshing morning swim, then drive to nearby Falls Park on the Reedy or The Peace Centre. This hotel offers free breakfast, WiFi, and parking. After exploring local attractions, return to comfortable accommodation with attentive staff ready to assist. --- "Friendly staff, very comfortable room, excellent hot breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £114 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Easley-Hotels-Hampton-Inn-Easley.h1453465.Hotel-Information) ![Reception hall](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/959a330b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/4d00561c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/d217b18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/241a5cc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Patrick Square [](https://www.expedia.co.uk/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) Clemson 9.8/10 Exceptional (783) Located in Clemson, this inviting inn offers complimentary perks including WiFi, wired internet, and self parking. Just a 5-minute drive from Clemson University, the hotel features clean rooms and a 24-hour front desk. Nearby attractions include the Clemson Area African American Museum. --- "Clean room. Nice front desk concierge. Very cute hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anisha £124 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ![Deluxe Single Room | Desk, laptop workspace](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/ee982916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/aa81a96a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room | Desk, laptop workspace](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/ab207998.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/9b0a6f2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SUN AND SAND MOTEL [](https://www.expedia.co.uk/Spartanburg-Hotels-SUN-AND-SAND-MOTEL.h118207809.Hotel-Information) Spartanburg 6.6/10 (10) Budget-friendly motel offering 24-hour front desk assistance near Cleveland Preserve Farm. Convenient to Peter's Creek Heritage Preserve and just a short drive from Spartanburg Station and Greenville-Spartanburg Airport. --- "Wonderful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather £51 includes taxes & fees 16 Dec - 17 Dec [](https://www.expedia.co.uk/Spartanburg-Hotels-SUN-AND-SAND-MOTEL.h118207809.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/05d8cd44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/e43af84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson University's James F. Martin Inn [](https://www.expedia.co.uk/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) Clemson 9.6/10 Exceptional (960) Located alongside a golf course, this charming inn offers easy access to Clemson University. Guests love the seasonal outdoor pool, poolside bar, and American dining at Sole on the Green. Enjoy free WiFi, free parking, and 24-hour fitness facilities during your campus visit. --- "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mindi £124 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible (Hearing, Roll-In Shower) | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/d36e662a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/2bb8d81a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Seneca Clemson [](https://www.expedia.co.uk/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) Seneca 9.2/10 Wonderful (792) Located just a 5-minute drive from Clemson University, this hotel offers a fitness centre and friendly staff. Enjoy complimentary on-the-go breakfast daily, free WiFi, and convenient parking. Littlejohn Coliseum and Sloan Tennis Centre are located nearby. --- "Michail was the best. He was so welcoming, helpful and professional. Parking was easy and rooms were nice and clean. I will definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jakeria £78 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/7f8f2b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/6228400c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/ca80b104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area [](https://www.expedia.co.uk/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) Clemson 8.2/10 Very good (1001) This business-friendly hotel offers a seasonal outdoor pool and fitness centre just 15 minutes from campus. Enjoy free breakfast and parking while exploring nearby African American Museum and Waterfront Park. Guests praise the helpful staff and clean rooms. --- "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda £77 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/f974826b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/0aaf2649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/e6475e9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/d16127a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Boutique Hotel, BW Signature Collection [](https://www.expedia.co.uk/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) Greenville 8.0/10 Very good (927) Situated close to Bon Secours Wellness Arena and Falls Park on the Reedy, this comfortable motel offers complimentary breakfast and WiFi. Enjoy a drink at the bar after exploring nearby attractions. Guests rave about the helpful staff and cosy beds. --- "The staff was very accommodating of my special needs. I d stayed here before and love this place. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dorothea £51 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/75fc615c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/cee4afe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/6ae45980.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, dishwasher, cookware/dishes/utensils](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/43d7334f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Greenville Downtown [](https://www.expedia.co.uk/Greenville-Hotels-Home2-Suites-By-Hilton-Greenville-Downtown.h15217348.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (1004) This city centre Greenville hotel offers a seasonal outdoor pool and 24-hour fitness centre, plus free breakfast and WiFi. Close to Greenville Convention Centre and Haywood Mall, with helpful staff ready to enhance your visit. --- "Great shopping nearby" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jordan £88 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Home2-Suites-By-Hilton-Greenville-Downtown.h15217348.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/d191b963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Resort Studio with Kitchen and Two Queen | Private kitchen](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/70e13494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson [](https://www.expedia.co.uk/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) Seneca 9.0/10 Wonderful (1001) Relax at this Seneca hotel featuring a seasonal outdoor pool, poolside bar, and hot tub. Located near Lake Keowee and Clemson University, guests enjoy the 24-hour fitness centre, restaurant, and bar. Clean rooms, helpful staff, and free WiFi and parking complete your stay. --- "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gene £101 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/afac9f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/dfd5de25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking (Efficiency) | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/7f3f162b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/6b7207b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Greenville Airport [](https://www.expedia.co.uk/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) Greenville 8.2/10 Very good (301) Located just 10 minutes from Haywood Mall and BMW Performance Centre, this practical hotel offers free WiFi and parking. Business travellers appreciate the 24-hour front desk and proximity to Bon Secours Wellness Arena for a convenient Greenville stay. --- "Clean room, friendly staff, I would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa £65 includes taxes & fees 17 Dec - 18 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/313b57b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/ce65516b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/877edfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Seneca-Clemson Area [](https://www.expedia.co.uk/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) Seneca 9.2/10 Wonderful (662) Situated near Lake Keowee and Lake Hartwell, this hotel offers a seasonal outdoor pool and 24-hour fitness centre. Business travellers appreciate the free WiFi, parking, and breakfast, while guests rave about the clean rooms and helpful staff. --- "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £84 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![In-room safe, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (743) Experience college town charm at this modern hotel, just a 10-minute walk from Clemson University and Lake Hartwell. Enjoy cocktails at the bar or savour a meal at the acclaimed restaurant with convenient room service available. --- "Staff was amazing and our room was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda R £137 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/a1d7ed0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/01b325b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/7c5ccfc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Greenville Downtown [](https://www.expedia.co.uk/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) Greenville Downtown 9.0/10 Wonderful (1004) Explore city centre from this stylish hotel featuring a refreshing outdoor pool and lively bar. Walk 20 minutes to Greenville Station or drive to Bon Secours Wellness Arena in under 10 minutes. The fitness centre and terrace enhance your urban retreat. --- "Perfect place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie £103 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/a9edd66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave (with Sofabed) | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/188dc421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson [](https://www.expedia.co.uk/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) Seneca 8.4/10 Very good (642) Located just a 10-minute drive from Clemson University, this hotel offers a seasonal outdoor pool and complimentary buffet breakfast served daily. Free WiFi and parking add value, while the helpful staff ensures a pleasant experience. Gignilliat Community Centre is nearby. --- "The stay was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabatha £73 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/34000000/33410000/33403500/33403422/6940a631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/34000000/33410000/33403500/33403422/ac5828ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/34000000/33410000/33403500/33403422/00b3b1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33410000/33403500/33403422/fbaccdbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Greenville Woodruff Road [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Greenville-Woodruff-Road.h33403422.Hotel-Information) Greenville 9.2/10 Wonderful (286) Discover vibrant accommodation minutes from Haywood Mall and Bon Secours Wellness Arena. This hotel offers free breakfast, WiFi, and parking, plus an indoor pool and 24-hour fitness centre. Guests consistently praise the helpful staff for enhancing their stay. --- "The room was clean, staff was great, breakfast had a good variety, and the pool was warm on a cold day!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlita £79 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Greenville-Woodruff-Road.h33403422.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1980000/1973100/1973047/d634c8dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1980000/1973100/1973047/2bbdf0b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1980000/1973100/1973047/54852175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1980000/1973100/1973047/6346dbb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Greenville [](https://www.expedia.co.uk/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h1973047.Hotel-Information) Greenville 9.0/10 Wonderful (393) Enjoy well-appointed accommodation with sofa beds and refrigerators at this Greenville hotel. Take a swim in the outdoor pool, grab a bite at the snack bar, or work out anytime. Free breakfast, WiFi, and parking add value near local attractions. --- "Very cleaned and great breakfast selection " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pedro £94 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h1973047.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/00aa6485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/c6ba3fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/72df685d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/3a9e98a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Greenville - Woodruff Road by IHG [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Holiday-Inn-Woodruff-Road.h41964398.Hotel-Information) Greenville 8.6/10 Excellent (669) Located near Haywood Mall and the Convention Centre, this hotel offers an indoor pool and workout facilities. Grab food at the restaurant or drinks at the bar. Free WiFi and parking make your stay seamless while friendly staff ensure a comfortable experience. --- "Friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Candice £97 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Holiday-Inn-Woodruff-Road.h41964398.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/a8a35598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/bacb8452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/e3dd7e0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/31000000/30470000/30468900/30468866/cb13a9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Duncan [](https://www.expedia.co.uk/Duncan-Hotels-Home2-Suites-By-Hilton-Duncan.h30468866.Hotel-Information) Duncan 9.4/10 Exceptional (283) Set in Duncan, this welcoming hotel offers a seasonal outdoor pool and 24-hour fitness centre. Enjoy free breakfast, WiFi, and parking while being just a short drive from BMW Performance Centre and River Falls Golf Course. --- "The lady that greeted us was excellent and exceptional " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Manuel £89 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/Duncan-Hotels-Home2-Suites-By-Hilton-Duncan.h30468866.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29®ionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Upstate South Carolina, SC Showing deals for:**26 Dec - 28 Dec** ### Image gallery for Lake Retreat House ![Smart TV](https://images.trvl-media.com/lodging/71000000/70560000/70558900/70558812/0bf818c3.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Lake Retreat House Anderson **10/10**Exceptional (20 reviews) 5% off £1,029 for 2 nights, 1 home £514 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=70558812&adults=2) ### Image gallery for Modern amenities in a rustic landscape ![Outdoor dining](https://images.trvl-media.com/lodging/84000000/83610000/83604700/83604625/de53ead0.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Modern amenities in a rustic landscape Cedar Mountain **9.6/10**Exceptional (16 reviews) 7% off £592 for 2 nights, 1 cabin £296 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=83604625&adults=2) ### Image gallery for Keowee Key \~ Cozy Condo \~ Golf Course View - Amenities ![Interior](https://images.trvl-media.com/lodging/65000000/64690000/64687300/64687226/8ceb08a5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Keowee Key \~ Cozy Condo \~ Golf Course View - Amenities Salem **10/10**Exceptional (71 reviews) 6% off £459 for 2 nights, 1 apartment £230 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=64687226&adults=2) ### Image gallery for Great Getaway ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/73000000/72940000/72935400/72935347/b3f26787.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Great Getaway Clemson **10/10**Exceptional (22 reviews) 7% off £800 for 2 nights, 1 home £400 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=72935347&adults=2) ### Image gallery for The Rustic Rectangle ![Outdoor dining](https://images.trvl-media.com/lodging/64000000/63370000/63362400/63362340/90e5f707.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Rustic Rectangle Pendleton **10/10**Exceptional (10 reviews) 6% off £436 for 2 nights, 1 home £218 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=63362340&adults=2) ### Image gallery for Broyles Landing Cottage at Lake Hartwell SC ![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110820000/110812100/110812036/6ebe1f2d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Broyles Landing Cottage at Lake Hartwell SC Townville **10/10**Exceptional (16 reviews) 7% off £257 for 2 nights, 1 cottage £129 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=110812036&adults=2) ### Image gallery for Clemson Cottage -close to University and lakes ![TV](https://images.trvl-media.com/lodging/72000000/71390000/71383400/71383348/ac2ab49e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Clemson Cottage -close to University and lakes Seneca **10/10**Exceptional (16 reviews) 6% off £330 for 2 nights, 1 apartment £165 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=71383348&adults=2) ### Image gallery for Hotel Hartness ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Hartness Greenville **9.8/10**Exceptional (626 reviews) 9% off £403 for 2 nights, 1 room £202 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=89689223&adults=2) ### Image gallery for The Station by Compo Hotels ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### The Station by Compo Hotels Travelers Rest **10/10**Exceptional (15 reviews) 13% off £463 for 2 nights, 1 room £231 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=88361952&adults=2) ### Image gallery for Extended Stay America Premier Suites - Greenville - Spartanburg - I-85 ![Lobby](https://images.trvl-media.com/lodging/97000000/96870000/96862800/96862776/f0a08506.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Extended Stay America Premier Suites - Greenville - Spartanburg - I-85 Duncan **8.6/10**Excellent (196 reviews) 10% off £124 for 2 nights, 1 room £62 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=96862776&adults=2) ### Image gallery for Clemson Weekend Rental- very close to campus, 4 Bedroom 3 Bathroom ![Private kitchen](https://images.trvl-media.com/lodging/120000000/119730000/119725500/119725474/345e9778.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Clemson Weekend Rental- very close to campus, 4 Bedroom 3 Bathroom Clemson **10/10**Exceptional (1 review) 15% off £1,679 for 2 nights, 1 home £840 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=119725474&adults=2) ### Image gallery for Unique lakefront 3 BR cabin directly on Lake Hartwell! 20 min drive to Clemson! ![Smart TV, fireplace, DVD player, video library](https://images.trvl-media.com/lodging/104000000/103120000/103117200/103117135/ae0f3c35.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Unique lakefront 3 BR cabin directly on Lake Hartwell! 20 min drive to Clemson! Townville **10/10**Exceptional (14 reviews) 6% off £690 for 2 nights, 1 cabin £345 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=103117135&adults=2) ### Image gallery for NEW!Lakefront retreat with huge dock, private cove. Perfect for Clemson Football ![Outdoor dining](https://images.trvl-media.com/lodging/85000000/84120000/84112700/84112636/w1170h877x0y3-b45d39c0.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### NEW!Lakefront retreat with huge dock, private cove. Perfect for Clemson Football Central **10/10**Exceptional (30 reviews) 7% off £1,059 for 2 nights, 1 home £530 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=84112636&adults=2) ### Image gallery for Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath ![Terrace/patio](https://images.trvl-media.com/lodging/76000000/75840000/75831400/75831331/e3f0a67e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath Anderson **10/10**Exceptional (77 reviews) 6% off £1,000 for 2 nights, 1 home £500 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=75831331&adults=2) ### Image gallery for Private Studio w/ Kitchen and Patio ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38940000/38938600/38938501/75455fc8.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Private Studio w/ Kitchen and Patio Central **9.6/10**Exceptional (10 reviews) 7% off £247 for 2 nights, 1 apartment £123 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=38938501&adults=2) ### Image gallery for Historical Farm Cottage Retreat near Clemson ![Exterior](https://images.trvl-media.com/lodging/35000000/34440000/34432900/34432894/2752300d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Historical Farm Cottage Retreat near Clemson Westminster **10/10**Exceptional (32 reviews) 6% off £306 for 2 nights, 1 home £153 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=34432894&adults=2) ### Image gallery for Dujardins waterfront lake Keowee home, with double dock on a deep, wide cove... ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33970000/33966600/33966552/6196336e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Dujardins waterfront lake Keowee home, with double dock on a deep, wide cove... West Union **9.8/10**Exceptional (75 reviews) 6% off £912 for 2 nights, 1 home £456 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=33966552&adults=2) ### Image gallery for Adorable & recently renovated condo within walking distance to downtown Clemson. ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90860000/90859000/90858915/c7bb99e6.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Adorable & recently renovated condo within walking distance to downtown Clemson. Clemson **10/10**Exceptional (27 reviews) 6% off £379 for 2 nights, 1 apartment £189 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=90858915&adults=2) ### Image gallery for Eagle's Nest by Table Rock. Perfect for Hickers, Cyclers, and Swimmers. ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/65000000/64460000/64450800/64450743/9cf07ee1.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Eagle's Nest by Table Rock. Perfect for Hickers, Cyclers, and Swimmers. Sunset **8.0/10**Very good (10 reviews) 6% off £484 for 2 nights, 1 home £242 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=64450743&adults=2) ### Image gallery for Waterfront cottage with dock on Lake Hartwell ![Smart TV, DVD player, video library, stereo](https://images.trvl-media.com/lodging/64000000/63190000/63182800/63182726/aba71a50.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Waterfront cottage with dock on Lake Hartwell Townville **9.6/10**Exceptional (57 reviews) 6% off £460 for 2 nights, 1 home £230 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=63182726&adults=2) ### Image gallery for The Pendle-Tin ![Smart TV](https://images.trvl-media.com/lodging/88000000/87140000/87136100/87136049/9e5b3cae.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Pendle-Tin Pendleton **9.8/10**Exceptional (9 reviews) 6% off £333 for 2 nights, 1 home £167 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=87136049&adults=2) ### Image gallery for Updated Keowee Key Condo, Close to Clemson ![Property grounds](https://images.trvl-media.com/lodging/116000000/115920000/115918500/115918421/82363f08.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Updated Keowee Key Condo, Close to Clemson Salem **10/10**Exceptional (6 reviews) 6% off £517 for 2 nights, 1 apartment £258 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=115918421&adults=2) ### Image gallery for Resort Access - Lake - Pools -Pickleball - Gym. Spacious townhome for groups ![Exterior](https://images.trvl-media.com/lodging/89000000/88690000/88688900/88688880/1a79938e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Resort Access - Lake - Pools -Pickleball - Gym. Spacious townhome for groups Salem **10/10**Exceptional (29 reviews) 7% off £848 for 2 nights, 1 home £424 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=88688880&adults=2) ### Image gallery for Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson ![Property grounds](https://images.trvl-media.com/lodging/42000000/42000000/41991100/41991039/0cbbeb23.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson Anderson **10/10**Exceptional (93 reviews) 7% off £752 for 2 nights, 1 home £376 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-28&selected=41991039&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels) ## Stay near popular Southeastern United States attractions !["Clemson University is an American public, coeducational, land-grant and sea-grant research university located in Clemson, South Carolina, United States.More clemson images:"](https://images.trvl-media.com/place/6127431/81e51bd8-6dfc-4739-9fb0-b15a1329fa3d.jpg) ### Clemson University 4.7/5 (738 reviews) Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6127431) ![Exploring Falls Park on the Reedy in Downtown Greenville, South Carolina during a peaceful afternoon stroll with scenic views](https://images.trvl-media.com/place/6082697/4d276125-b8b6-4bd4-9887-c71157164970.jpg) ### Falls Park on the Reedy 4.7/5 (1,399 reviews) Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082697) ![The Peace Center, performing arts center and outdoor ampitheater, in Greenville, South Carolina downtown viewed from the Reedy River.](https://images.trvl-media.com/place/6082705/ac1b739b-8676-4fdf-9cff-f074f428659b.jpg) ### The Peace Center 4.3/5 (517 reviews) You can make plans for a show at The Peace Center during your trip to Greenville. Amble around this family-friendly area's riverfront or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082705) ### Bon Secours Wellness Arena 4.2/5 (601 reviews) Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082715) ### Haywood Mall 4.3/5 (952 reviews) During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6130785) ### Memorial Stadium 4.7/5 (201 reviews) Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6193935) ### BMW Performance Center 4.7/5 (50 reviews) You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6217409) ### Greenville Convention Center 4.2/5 (320 reviews) Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6125256) ## Learn more about Upstate South Carolina Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park. [See all hotels in Upstate South Carolina](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29&adults=2®ionId=6057939) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) Photo by Michelle Hendrix ## Top Upstate South Carolina Hotel Reviews ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Loved the breakfast and the amount of options available " [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Clean property and close to many,many shopping and dining options. Hotel staff extremely friendly. " [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Excellent " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "The room was immaculate. TV wouldn't change from the menu screen, that would be my only complaint. " [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "The room was very nice. Very spacious. The staff was very friendly. The location was great too. " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg) ### ECHO Suites Extended Stay by Wyndham Spartanburg 10/10 Excellent "I was impressed upon entrance to the lobby! Everything was clean in neat and the receptionist was AWESOME!" [](https://expedia.co.uk/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "Gorgeous, clean, unique, so special!!" [](https://expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Staff was great, awesome customer service! " [](https://expedia.co.uk/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Amazing staff and clean room" [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ## More cheap stays in Upstate South Carolina ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Anderson 1007 George Smith Mill Rd Anderson SC £52 17 Dec - 18 Dec includes taxes & fees 7.6/10 Good! (1,002 reviews) [](https://expedia.co.uk/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd](https://images.trvl-media.com/lodging/1000000/210000/202200/202137/b07dd898_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd 1024 Woodruff Rd Greenville SC £59 18 Dec - 19 Dec includes taxes & fees 8.2/10 Very Good! (1,001 reviews) [](https://expedia.co.uk/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h202137.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### ECHO Suites Extended Stay by Wyndham Spartanburg 490 W Blackstock Road Spartanburg SC £60 16 Dec - 17 Dec includes taxes & fees 8/10 Very Good! (290 reviews) [](https://expedia.co.uk/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Quality Inn Seneca Clemson Area US-123](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Seneca Clemson Area US-123 226 Hi Tech Rd Seneca SC £65 21 Dec - 22 Dec includes taxes & fees 7.8/10 Good! (664 reviews) [](https://expedia.co.uk/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Greenville I-385 Inn & Suites 831 Congaree Rd Greenville SC £66 21 Dec - 22 Dec includes taxes & fees 9/10 Wonderful! (1,413 reviews) [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Clemson Hotel & Conference Center 1310 Tiger Blvd Clemson SC £77 21 Dec - 22 Dec includes taxes & fees 8.2/10 Very Good! (1,001 reviews) [](https://expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ## Hotels in Upstate South Carolina with star rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 14 properties [](https://expedia.co.uk/4Star-Upstate-South-Carolina-Hotels.s40-0-d6057939.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 193 properties [](https://expedia.co.uk/3Star-Upstate-South-Carolina-Hotels.s30-0-d6057939.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 286 properties [](https://expedia.co.uk/2Star-Upstate-South-Carolina-Hotels.s20-0-d6057939.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### Where can I find the best nightlife in Upstate South Carolina? > In Greenville, the West End is a hotspot for nightlife, featuring a variety of trendy bars, craft breweries, and live music venues. Here, you can enjoy everything from laid-back pubs to upscale cocktail lounges, all set against the backdrop of the picturesque Reedy River. > > > Spartanburg's downtown area is also bustling with nightlife options. Main Street is lined with a range of bars and restaurants that offer everything from craft cocktails to local brews. You'll find a vibrant atmosphere, especially on weekends, making it a great spot to enjoy a night out with friends. > > > If you're in the mood for a more great experience, check out the local breweries scattered across the region. Many of them host live music events and have food trucks, providing a fun and casual way to spend an evening. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Upstate South Carolina hotel booking with Expedia? ### How much is the nightly rate at a Upstate South Carolina hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Brookhaven Hotels ](https://www.expedia.co.uk/Brookhaven-Hotels.d553248635975852330.Travel-Guide-Hotels) - [Chick Springs Hotels ](https://www.expedia.co.uk/Chick-Springs-Hotels.d553248635975847338.Travel-Guide-Hotels) - [Colonel Elias Earle Historic District Hotels ](https://www.expedia.co.uk/Colonel-Elias-Earle-Historic-District-Greenville-Hotels.0-n6348165-0.Travel-Guide-Filter-Hotels) - [Hotels near Discovery Island Water Park ](https://www.expedia.co.uk/Discovery-Island-Water-Park-Hotels.0-l553248621532656705-0.Travel-Guide-Filter-Hotels) - [Hotels near Donaldson Center ](https://www.expedia.co.uk/Donaldson-Center-Airport-Hotels.0-aGDC-0.Travel-Guide-Filter-Hotels) - 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