Find hotels in Upstate South Carolina, SC from £53
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25 Sept - 27 SeptOur top choices for Upstate South Carolina hotels
1. Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
Pedro
£86
includes taxes & fees
20 Sept - 21 Sept
2. Fairfield Inn & Suites by Marriott Greenville Simpsonville
Fairfield Inn & Suites by Marriott Greenville SimpsonvilleSimpsonville
Simone
£72
includes taxes & fees
27 Sept - 28 Sept
3. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
Microtel Inn & Suites by Wyndham Greenville / Woodruff RdGreenville
Charles
£57
includes taxes & fees
4 Oct - 5 Oct
4. Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
Sara
£62
includes taxes & fees
4 Oct - 5 Oct
5. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
Jalen
£68
includes taxes & fees
15 Sept - 16 Sept
6. Days Inn by Wyndham Greenville South/Mauldin
Days Inn by Wyndham Greenville South/MauldinMauldin
David
£59
includes taxes & fees
20 Sept - 21 Sept
7. Courtyard by Marriott Greenville Mauldin
Courtyard by Marriott Greenville MauldinGreenville
Leticia
£97
includes taxes & fees
20 Sept - 21 Sept
8. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHGGreenville
Paul
£69
includes taxes & fees
20 Sept - 21 Sept
9. Sleep Inn at Greenville Convention Cente
Sleep Inn at Greenville Convention CenteGreenville
Chris
£51
includes taxes & fees
4 Oct - 5 Oct
10. Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
Holiday Inn Express & Suites Greenville SE - Simpsonville by IHGSimpsonville
Alicia
£109
includes taxes & fees
20 Sept - 21 Sept
11. DoubleTree by Hilton Greenville Woodruff Road
DoubleTree by Hilton Greenville Woodruff RoadGreenville
Jeffery
£100
includes taxes & fees
20 Sept - 21 Sept
12. SpringHill Suites by Marriott Greenville Downtown
SpringHill Suites by Marriott Greenville DowntownGreenville Downtown
Douglas
£122
includes taxes & fees
4 Oct - 5 Oct
13. Extended Stay America Premier Suites Greenville Woodruff Rd
Extended Stay America Premier Suites Greenville Woodruff RdGreenville
Debra
£64
includes taxes & fees
20 Sept - 21 Sept
14. Hilton Greenville
Hilton GreenvilleGreenville
Edward
£96
includes taxes & fees
20 Sept - 21 Sept
15. Hyatt Place Greenville Downtown
Hyatt Place Greenville DowntownGreenville Downtown
Tamara
£106
includes taxes & fees
11 Oct - 12 Oct
16. Embassy Suites by Hilton Greenville Downtown Riverplace
Embassy Suites by Hilton Greenville Downtown RiverplaceGreenville Downtown
Ivy
£130
includes taxes & fees
27 Sept - 28 Sept
17. Hilton Garden Inn Greenville
Hilton Garden Inn GreenvilleGreenville
Pedro
£77
includes taxes & fees
20 Sept - 21 Sept
18. Courtyard by Marriott Greenville Downtown
Courtyard by Marriott Greenville DowntownGreenville Downtown
Shellie
£120
includes taxes & fees
27 Sept - 28 Sept
20. Hampton Inn & Suites Greenville-Downtown-RiverPlace
Hampton Inn & Suites Greenville-Downtown-RiverPlaceGreenville Downtown
James
£137
includes taxes & fees
20 Sept - 21 Sept
Holiday Rentals in Upstate South Carolina
Aparthotel
stayAPT Suites Greenville-Haywood Mall
stayAPT Suites Greenville-Haywood MallGreenville
"The rooms are spacious and feels like a and apartment. This place is one of the best places to stay."
Apartment
Mint House Greenville Downtown by Kasa
Mint House Greenville Downtown by KasaGreenville Downtown
"The unit was very clean, and I stay here whenever I'm in Greenville."
Cabin
Carolina Camp Cedar
Carolina Camp CedarPickens
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
Cottage
Cozy Greenville Bungalow ~ 2 Mi to Downtown!
Cozy Greenville Bungalow ~ 2 Mi to Downtown!Greenville
"Amazing place. Great host. "
Aparthotel
The Station by Compo Hotels
The Station by Compo HotelsTravelers Rest
"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."
Cabin
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
"Me and my family had a great time"
Aparthotel
Landing Apartments - Lyman
Landing Apartments - LymanLyman
"Great room that was nice and clean. Smooth check-in."
Cottage
Clemson Memorabilia House
Clemson Memorabilia HouseClemson
"We enjoyed our stay, it was the perfect size for our family of four. "
Cottage
Greer Guest House < 1 Mi to Park & Downtown Area!
Greer Guest House < 1 Mi to Park & Downtown Area!Greer
"Nice place en Greenville area "
Cottage
1 Mi to Downtown Greer: Family Home w/ Gazebo!
1 Mi to Downtown Greer: Family Home w/ Gazebo!Greer
"Very cute home close to everything. Super clean and spacious. Well furnished."
Cottage
Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar
Home w/ Lake Keowee Access: Sleeps 7, Coffee BarSeneca
"The best, perfect "
Cottage
4 Seasons of Fun! Walhalla Home w/ Spacious Yard!
4 Seasons of Fun! Walhalla Home w/ Spacious Yard!Walhalla
"The house was perfect for our group for our golf trip. We had one minor issue and we were able to speak to the host and they had someone to correct it quickly so that it didn’t disrupt our trip in any way. Place was clean, peaceful, with great hosts."
Apartment
Designer Retreat w/ Pool, Golf + Beach Access!
Designer Retreat w/ Pool, Golf + Beach Access!Salem
"Property is in a great community, and it was very clean and beautifully decorated."
Cottage
Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!
Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!Seneca
"Beautiful and quaint cabin! Highly recommend, great view of the lake."
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Stay near popular Upstate South Carolina attractions
Clemson University
9.6/10 (1,439 reviews)
Enjoy the student vibe around Clemson University, a top university in Clemson. Experience the area's theatre scene or attend a football match.
Falls Park on the Reedy
9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.
Bon Secours Wellness Arena
8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
Greenville Convention Center
8.4/10 (571 reviews)
Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
Memorial Stadium
9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.
BMW Performance Center
9.0/10 (90 reviews)
You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.
Haywood Mall
8.8/10 (1,681 reviews)
During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Frankie's Fun Park to Conestee Nature Preserve.
See all hotels in Upstate South Carolina
Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews
Comfort Suites At WestGate Mall
8/10 Good
"Good enough. I enjoyed my time"
Grand Bohemian Lodge Greenville, Autograph Collection
8/10 Good
"Room was not ready. Check in said 4:00 but we had to wait a long time and they couldn’t tell us when our room would be ready."
Mint House Greenville Downtown by Kasa
10/10 Excellent
"Parking was the only real issue I had because I arrived before I got the check-in email. Had I waited, i less if you’re gonna be playingt was perfectly clear what I needed to do. It was located in a very convenient place close to Falls Park. It was a spacious unit and everything was clean. Very pleased."
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
10/10 Excellent
"It was amazing, I love the staff the people and great communication"
Best Western Plus Clemson Hotel & Conference Center
10/10 Excellent
"Excellent all the way around."
Hotel Hartness
10/10 Excellent
"The room was immaculate and the staff was very friendly. Such a beautiful property that is nice to explore. Close to other restaurants and store nearby. Would definitely stay again."
Lakeside Lodge Clemson
10/10 Excellent
"Wow! We were very impressed with the suite and felt like it was brand new! I've stayed in some of the nicest hotels and condos in the country and this place is right in that ballpark! We'll stay there again."
Comfort Inn & Suites Clemson - University Area
10/10 Excellent
"The hotel was extremely clean and the breakfast delicious. Great location."
Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
"Clean, comfortable and convenient."
More cheap stays in Upstate South Carolina
WoodSpring Suites Spartanburg - Duncan
255 Frontage Rd. Duncan SC
£53
14 Sept - 15 Sept
includes taxes & fees
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
£62
4 Oct - 5 Oct
includes taxes & fees
Comfort Inn Greenville - Haywood Mall
246 Congaree Road Greenville SC
£68
4 Oct - 5 Oct
includes taxes & fees
8.2/10 Very good! (1,002 reviews)
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
£83
14 Sept - 15 Sept
includes taxes & fees
Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
£87
4 Oct - 5 Oct
includes taxes & fees
8.4/10 Very good! (1,004 reviews)
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
£100
14 Sept - 15 Sept
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
Hotels in Upstate South Carolina with star rating
4 Star Hotels
29 properties
3 Star Hotels
204 properties
2 Star Hotels
155 properties
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- 3 Star Hotels in Greenville - Spartanburg
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