Title: Hotels in Upstate South Carolina - Best Upstate South Carolina Hotels from £46 - Fully Refundable Options - Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina ![](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Upstate South Carolina Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&amenities=SPA_ON_SITE) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&amenities=HOT_TUB) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&amenities=POOL) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&lodging=CABIN) Resort [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&lodging=HOTEL_RESORT) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&lodging=COTTAGE) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&amenities=PETS) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&travelerType=family_friendly) Farm [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&lodging=AGRITOURISM) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&lodging=APARTMENT) Chalet [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-12&d1=2026-02-12&endDate=2026-02-14&d2=2026-02-14&lodging=CHALET) ## Check prices for these dates Tonight [29 Jan - 30 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [30 Jan - 31 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-30&endDate=2026-01-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina hotels ![Hallway](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/4d00561c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Café](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/893b2bfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/959a330b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/d217b18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Patrick Square [](https://www.expedia.co.uk/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) Clemson 9.8/10 Exceptional (794 reviews) - Book this charming hotel minutes from Clemson University with free WiFi and parking. "Clean room, great location, wonderful staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joyce £120 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/a5d6b89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.co.uk/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (561 reviews) - Stay close to Clemson University in a stylish hotel with a trendy bar and restaurant. "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan £226 includes taxes & fees 31 Jan - 1 Feb [](https://www.expedia.co.uk/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/60d71ae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/26b1d839.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/330446c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/3e3a13ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area [](https://www.expedia.co.uk/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) Clemson 8.2/10 Very good (1,000 reviews) - Experience a quiet, convenient stay near Clemson University and Lake Keowee. "Clean room. Friendly staff. Convenient location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anita £76 includes taxes & fees 4 Feb - 5 Feb [](https://www.expedia.co.uk/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Golf](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/ad943919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/63d829f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/0aec11f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson University's James F. Martin Inn [](https://www.expedia.co.uk/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) Clemson 9.6/10 Exceptional (965 reviews) - Experience Walker Golf Course and Clemson campus just steps from this lakeside inn. "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mindi £120 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/f1cbacdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/34438b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/462068d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn @ Clemson [](https://www.expedia.co.uk/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) Clemson 8.2/10 Very good (1,007 reviews) - Book a peaceful stay minutes from campus with free Wi-Fi and parking. "Love this hotel. It’s a little home away from home for me ❤️❤️❤️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacey [](https://www.expedia.co.uk/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Free breakfast ](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/282fab11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2557x3y4-ce9cc597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/aa533fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center [](https://www.expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) Clemson 8.2/10 Very good (1,001 reviews) - Enjoy lakeside stays close to Clemson University with 24-hour fitness centre. "Rooms are clean. Staff was very pleasant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Regina £76 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/ff716430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible (Mobility Accessible, Communications) | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/5d59466d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/78b30d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/w6000h3996x0y0-b212d0d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Clemson by IHG [](https://www.expedia.co.uk/Anderson-Hotels-Holiday-Inn-Express-Suites-Clemson.h2558616.Hotel-Information) Clemson 8.8/10 Excellent (957 reviews) - Enjoy easy access to Clemson University and free breakfast at this welcoming hotel. "Nice facility " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rishandrea £99 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Anderson-Hotels-Holiday-Inn-Express-Suites-Clemson.h2558616.Hotel-Information) ![Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/7000000/6180000/6172800/6172789/d912dcd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6180000/6172800/6172789/9a681c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6180000/6172800/6172789/932eed0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/7000000/6180000/6172800/6172789/dd7fbc82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Greenville South/Mauldin [](https://www.expedia.co.uk/Mauldin-Hotels-Days-Inn-By-Wyndham-Greenville-SouthMauldin.h6172789.Hotel-Information) Mauldin 7.4/10 Good (665 reviews) - Take a dip in the seasonal outdoor pool near Greenville Convention Centre. "Staff was friendly, room was clean. Looks like they've done recent renovations. Only issue was noise level between rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kate £55 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Mauldin-Hotels-Days-Inn-By-Wyndham-Greenville-SouthMauldin.h6172789.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/f08daaa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/d8583276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/c9a89e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/7636779c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Points by Sheraton Spartanburg [](https://www.expedia.co.uk/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) Spartanburg 9.4/10 Exceptional (448 reviews) "Friendly staff, clean rooms, excellent food! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley £81 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/7bf4f5bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/ff5159b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/d9e7f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/8c0b8a30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Spartanburg [](https://www.expedia.co.uk/Spartanburg-Hotels-Hilton-Garden-Inn-Spartanburg.h31356806.Hotel-Information) Spartanburg 9.4/10 Exceptional (498 reviews) - Relax in Spartanburg with a heated pool, chic bar, and attentive service. "Very nice lady at check in" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £95 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Spartanburg-Hotels-Hilton-Garden-Inn-Spartanburg.h31356806.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/2fa8ed98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/33c2ff7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/bd6af703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/a1ae62a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Spartanburg-North I-85 [](https://www.expedia.co.uk/Spartanburg-Hotels-Hampton-Inn-Spartanburg-North-I-85.h281618.Hotel-Information) Spartanburg 8.6/10 Excellent (1,001 reviews) - Quiet retreat with a seasonal pool and free breakfast near Spartanburg attractions. "Great staff, clean room, good location. Would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randall £68 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Spartanburg-Hotels-Hampton-Inn-Spartanburg-North-I-85.h281618.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/dfd5de25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/26c9fcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/8ef1c109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/7cd027cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Greenville Airport [](https://www.expedia.co.uk/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) Greenville 8.4/10 Very good (332 reviews) - Experience efficient extended stays minutes from Greenville-Spartanburg Airport. "everything was perfect " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Makiya £63 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/5b31fd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (753 reviews) - Relax in city centre Clemson near the university with a top-rated restaurant. "Awesome hotel and very convenient for visiting Clemson." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina £152 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/d02ac737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/b1fdad7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/e845fce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast ](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/1b324965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Spartanburg Northwest [](https://www.expedia.co.uk/Spartanburg-Hotels-Best-Western-Spartanburg-Northwest.h19764.Hotel-Information) Spartanburg 8.2/10 Very good (828 reviews) - Convenient Spartanburg stay with pool, fitness centre, and helpful staff. "The lady who worked front desk at night (6PM) when we checked in was very courteous. She was very pleasant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul £68 includes taxes & fees 6 Feb - 7 Feb [](https://www.expedia.co.uk/Spartanburg-Hotels-Best-Western-Spartanburg-Northwest.h19764.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/9354fd9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/36aa2afa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/952b2a17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites At WestGate Mall [](https://www.expedia.co.uk/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) Spartanburg 8.2/10 Very good (1,000 reviews) - Modern comfort near WestGate Mall with outdoor seasonal pool and fitness centre. "Easy to get in and out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £73 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/0ab02d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/9b0a6f2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/aa81a96a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room | Desk, laptop workspace](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/ab207998.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SUN AND SAND MOTEL [](https://www.expedia.co.uk/Spartanburg-Hotels-SUN-AND-SAND-MOTEL.h118207809.Hotel-Information) Spartanburg 7.2/10 Good (15 reviews) - Enjoy Spartanburg comfort with free parking and daily housekeeping service. "It was nice and cheap ...just wished my tv worked" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £46 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Spartanburg-Hotels-SUN-AND-SAND-MOTEL.h118207809.Hotel-Information) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/97861c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/54c737da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/744c0880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/c3da6451.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG [](https://www.expedia.co.uk/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) Spartanburg 9.0/10 Wonderful (720 reviews) - Experience comfort near Westgate Mall with an indoor pool and free breakfast. "The room was spacious and perfect for our one night stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond £83 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) ![3 restaurants, breakfast, dinner served; Modern European cuisine ](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/b0cbe2b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/1ee7acc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/1274294b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/20000000/19220000/19218500/19218492/2016aea9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel by Marriott Spartanburg [](https://www.expedia.co.uk/Spartanburg-Hotels-AC-Hotel-By-Marriott-Spartanburg.h19218492.Hotel-Information) Spartanburg 9.4/10 Exceptional (604 reviews) - Stay right in the entertainment district with fitness centre and dining options nearby. "Best place to stay in Spartanburg " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank £128 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Spartanburg-Hotels-AC-Hotel-By-Marriott-Spartanburg.h19218492.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/b55e4e9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/72df685d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/c6ba3fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/3a9e98a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Greenville - Woodruff Road by IHG [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Holiday-Inn-Woodruff-Road.h41964398.Hotel-Information) Greenville 8.6/10 Excellent (673 reviews) - Enjoy convenient access to Greenville's attractions with fitness and dining options. "Friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Candice £90 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Holiday-Inn-Woodruff-Road.h41964398.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/f974826b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/41944efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/4196fe01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/e6475e9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Boutique Hotel, BW Signature Collection [](https://www.expedia.co.uk/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) Greenville 8.0/10 Very good (949 reviews) - Experience Greenville's charm at a boutique motel with free breakfast and parking. "clean room, staff, amenities" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carl £49 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-12&endDate=2026-02-13®ionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Holiday Rentals in Upstate South Carolina Cottage ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/ce6330d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/925daccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/6f31060d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/1cbd1706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Updated Greenville Home w/ Backyard! [](https://www.expedia.co.uk/Greenville-Hotels-Updated-Greenville-Home-W-Backyard.h98548744.Hotel-Information) Greenville 10/10 Exceptional (2 reviews) [](https://www.expedia.co.uk/Greenville-Hotels-Updated-Greenville-Home-W-Backyard.h98548744.Hotel-Information) Aparthotel ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/61217476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/464c71ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/cc01b08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/2d11b158.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Greenville-Haywood Mall [](https://www.expedia.co.uk/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information) Greenville 9.0/10 Wonderful (201 reviews) "Great place!" [](https://www.expedia.co.uk/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information) Cottage ![Interior](https://images.trvl-media.com/lodging/102000000/101440000/101436300/101436203/777a66b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms, Non Smoking, Patio | Living room | 50-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/102000000/101440000/101436300/101436203/912c041a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms, Non Smoking, Patio | 2 bedrooms, individually decorated, individually furnished](https://images.trvl-media.com/lodging/102000000/101440000/101436300/101436203/w2993h1688x0y0-33a0ecc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms, Non Smoking, Patio | Living room | 50-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/102000000/101440000/101436300/101436203/w3000h5321x0y0-a21b6da0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Frank Howard 111 Farmhouse [](https://www.expedia.co.uk/Clemson-Hotels-Frank-Howard-111-Farmhouse.h101436203.Hotel-Information) Clemson 9.8/10 Exceptional (10 reviews) "Great stay " [](https://www.expedia.co.uk/Clemson-Hotels-Frank-Howard-111-Farmhouse.h101436203.Hotel-Information) Cabin ![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f29b16c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/53271cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/2da98b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy [](https://www.expedia.co.uk/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) Seneca 9.8/10 Exceptional (57 reviews) "Excellent stay." [](https://www.expedia.co.uk/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) Aparthotel ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/fa38c3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vista Wedge Cottage | Private kitchen | Full-sized fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/9304eefe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/87440d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Station by Compo Hotels [](https://www.expedia.co.uk/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) Travelers Rest 10/10 Exceptional (16 reviews) "great place perfect for more privacy vs. a standard hotel" [](https://www.expedia.co.uk/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) Apartment ![Meeting facility](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/cc0792c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/1a65f92e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Three Bedroom (Self Check-in with Virtual Front Desk) | Laptop workspace, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/531378f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Three Bedroom (Self Check-in with Virtual Front Desk) | Laptop workspace, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/ab577597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mint House Greenville Downtown by Kasa [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (789 reviews) "Spotless wonderful stay" [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) Cottage ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/784635bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/1767b060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/6c10521c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/e4c6187d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront Seneca Cabin \~ 4 Mi to Boat Launch! [](https://www.expedia.co.uk/Seneca-Hotels-Waterfront-Seneca-Cabin-4-Mi-To-Boat-Launch.h103707807.Hotel-Information) Seneca 10/10 Exceptional (1 review) "Beautiful and quaint cabin! Highly recommend, great view of the lake." [](https://www.expedia.co.uk/Seneca-Hotels-Waterfront-Seneca-Cabin-4-Mi-To-Boat-Launch.h103707807.Hotel-Information) Apartment ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/869da7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/456ccd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/5314fa58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/ad6d8353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Designer Retreat w/ Pool, Golf + Beach Access! [](https://www.expedia.co.uk/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) Salem 10/10 Exceptional (1 review) "Property is in a great community, and it was very clean and beautifully decorated." [](https://www.expedia.co.uk/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) Cottage ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/b9728109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/6a3ca44f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/91d5d964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/8108d915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Claires Cottage \~ 4 Mi to Downtown Greenville! [](https://www.expedia.co.uk/Greenville-Hotels-Charming-Cottage-4-Mi-To-Downtown-Greenville.h94965665.Hotel-Information) Greenville 10/10 Exceptional (1 review) "Great trip. The small cottage was perfect for my wife and I and the owner was very responsive." [](https://www.expedia.co.uk/Greenville-Hotels-Charming-Cottage-4-Mi-To-Downtown-Greenville.h94965665.Hotel-Information) Cottage ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551000/98550977/79219c5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551000/98550977/1de2cbd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551000/98550977/9b661a37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551000/98550977/074e90eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greer Guest House < 1 Mi to Park & Downtown Area! [](https://www.expedia.co.uk/Greer-Hotels-Greer-Guest-House-1-Mi-To-Park-Downtown-Area.h98550977.Hotel-Information) Greer 10/10 Exceptional (2 reviews) "Nice place en Greenville area " [](https://www.expedia.co.uk/Greer-Hotels-Greer-Guest-House-1-Mi-To-Park-Downtown-Area.h98550977.Hotel-Information) Cottage ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/89d76ac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/506b693f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/1b10d271.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/3e1d7748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront Lake Hartwell Vacation Rental w/ Dock! [](https://www.expedia.co.uk/Townville-Hotels-Waterfront-Lake-Hartwell-Vacation-Rental-W-Dock.h98553702.Hotel-Information) Townville 10/10 Exceptional (1 review) [](https://www.expedia.co.uk/Townville-Hotels-Waterfront-Lake-Hartwell-Vacation-Rental-W-Dock.h98553702.Hotel-Information) Cottage ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/309d8bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/34ff4e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/6247e045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/86d9c4f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deck, Grill & Dock Access: Lake Keowee Retreat! [](https://www.expedia.co.uk/Seneca-Hotels-Deck.h113184450.Hotel-Information) Seneca 10/10 Exceptional (1 review) "The best, perfect " [](https://www.expedia.co.uk/Seneca-Hotels-Deck.h113184450.Hotel-Information) Cottage ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537700/93537627/a77a5211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537700/93537627/30009dd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537700/93537627/603934e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537700/93537627/f2e0e083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cleveland Home w/ South Saluda Fishing Access [](https://www.expedia.co.uk/Cleveland-Hotels-Cleveland-Home-W-South-Saluda-Fishing-Access.h93537627.Hotel-Information) Cleveland 10/10 Exceptional (1 review) "This was a fishing trip that myself and a couple of my friends went on. The cabin was exactly as described in the listing and then some. Very clean and had every amenity you could think of. The host lives next door and went above and beyond making sure we had everything we needed and were comfortable. He even lent us his state pass to get into the parks and supplied his vast knowledge of where and what to use for fishing in the creeks. Will definitely be going back sometime in the near future." [](https://www.expedia.co.uk/Cleveland-Hotels-Cleveland-Home-W-South-Saluda-Fishing-Access.h93537627.Hotel-Information) Cottage ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94510000/94502500/94502491/53bf320b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94510000/94502500/94502491/8c0f98dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94510000/94502500/94502491/dc73b5c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94510000/94502500/94502491/ea0ddd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakefront South Carolina Abode w/ Deck & Boat Dock [](https://www.expedia.co.uk/Fair-Play-Hotels-Waterfront-Lake-Hartwell-Cabin-Wdock-Near-Clemson.h94502491.Hotel-Information) Fair Play 9.0/10 Wonderful (2 reviews) "clean room, family friendly " [](https://www.expedia.co.uk/Fair-Play-Hotels-Waterfront-Lake-Hartwell-Cabin-Wdock-Near-Clemson.h94502491.Hotel-Information) Apartment ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/d4764610.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/a6a33cb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/26081583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/a232b415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serene Travelers Rest Apartment: 7 Mi to Downtown! [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Serene-Travelers-Rest-Apartment-7-Mi-To-Downtown.h107978043.Hotel-Information) Travelers Rest 10/10 Exceptional (1 review) "The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! " [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Serene-Travelers-Rest-Apartment-7-Mi-To-Downtown.h107978043.Hotel-Information) [See all holiday rentals](https://expedia.co.uk/Hotel-Search?startDate=2026-02-26&endDate=2026-03-01®ionId=6057939&adults=2&sort=RECOMMENDED&stay_options_group=vacation_rentals_option&categorySearch=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels) ## Stay near popular Southeastern United States attractions !["Clemson University is an American public, coeducational, land-grant and sea-grant research university located in Clemson, South Carolina, United States.More clemson images:"](https://images.trvl-media.com/place/6127431/81e51bd8-6dfc-4739-9fb0-b15a1329fa3d.jpg) ### Clemson University 4.7/5 (738 reviews) Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6127431) ![Exploring Falls Park on the Reedy in Downtown Greenville, South Carolina during a peaceful afternoon stroll with scenic views](https://images.trvl-media.com/place/6082697/4d276125-b8b6-4bd4-9887-c71157164970.jpg) ### Falls Park on the Reedy 4.7/5 (1,399 reviews) Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082697) ### Bon Secours Wellness Arena 4.2/5 (601 reviews) Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the acclaimed theatre scene in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082715) ### Haywood Mall 4.3/5 (952 reviews) During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6130785) ### BMW Performance Center 4.7/5 (50 reviews) You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6217409) ### Memorial Stadium 4.7/5 (201 reviews) Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6193935) ## Learn more about Upstate South Carolina Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park. [See all hotels in Upstate South Carolina](https://www.expedia.co.uk/Hotel-Search?startDate=2026-02-12&endDate=2026-02-13&adults=2®ionId=6057939) ![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by Visit Greenville, South Carolina ## Top Upstate South Carolina Hotel Reviews ## More cheap stays in Upstate South Carolina ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Anderson 1007 George Smith Mill Rd Anderson SC £51 1 Feb - 2 Feb includes taxes & fees 7.8/10 Good! (1,009 reviews) [](https://expedia.co.uk/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd](https://images.trvl-media.com/lodging/1000000/210000/202200/202137/b07dd898_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd 1024 Woodruff Rd Greenville SC £55 16 Feb - 17 Feb includes taxes & fees 8.2/10 Very Good! (1,004 reviews) [](https://expedia.co.uk/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h202137.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### ECHO Suites Extended Stay by Wyndham Spartanburg 490 W Blackstock Road Spartanburg SC £61 1 Feb - 2 Feb includes taxes & fees 8/10 Very Good! (332 reviews) [](https://expedia.co.uk/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Greenville I-385 Inn & Suites 831 Congaree Rd Greenville SC £62 1 Feb - 2 Feb includes taxes & fees 9/10 Wonderful! (1,429 reviews) [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Quality Inn Seneca Clemson Area US-123](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Seneca Clemson Area US-123 226 Hi Tech Rd Seneca SC £66 4 Feb - 5 Feb includes taxes & fees 7.8/10 Good! (670 reviews) [](https://expedia.co.uk/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Clemson Hotel & Conference Center 1310 Tiger Blvd Clemson SC £76 2 Feb - 3 Feb includes taxes & fees 8.2/10 Very Good! (1,000 reviews) [](https://expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ## Hotels in Upstate South Carolina with star rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 11 properties [](https://expedia.co.uk/4Star-Upstate-South-Carolina-Hotels.s40-0-d6057939.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 194 properties [](https://expedia.co.uk/3Star-Upstate-South-Carolina-Hotels.s30-0-d6057939.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 315 properties [](https://expedia.co.uk/2Star-Upstate-South-Carolina-Hotels.s20-0-d6057939.Travel-Guide-Filter-Hotels) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - 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