Photo by Visit Greenville, South Carolina

Find hotels in Upstate South Carolina, SC from £54
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is £143
includes taxes & fees
17 Mar - 18 Mar

Holiday Inn Spartanburg Northwest by IHG
Holiday Inn Spartanburg Northwest by IHGSpartanburg
7.6 out of 10, Good, (835 reviews)
The price is £78
includes taxes & fees
4 Apr - 5 Apr

Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University AreaClemson
8.2 out of 10, Very good, (1,003 reviews)
The price is £88
includes taxes & fees
22 Mar - 23 Mar

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (808 reviews)
The price is £133
includes taxes & fees
23 Mar - 24 Mar

The Abernathy of Clemson
The Abernathy of ClemsonClemson
9.6 out of 10, Exceptional, (574 reviews)
The price is £134
includes taxes & fees
22 Mar - 23 Mar

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very good, (1,006 reviews)
The price is £83
includes taxes & fees
17 Mar - 18 Mar

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (982 reviews)
The price is £125
includes taxes & fees
19 Mar - 20 Mar

Hilton Garden Inn Spartanburg
Hilton Garden Inn SpartanburgSpartanburg
9.4 out of 10, Exceptional, (503 reviews)
The price is £96
includes taxes & fees
22 Mar - 23 Mar

Four Points by Sheraton Spartanburg
Four Points by Sheraton SpartanburgSpartanburg
9.4 out of 10, Exceptional, (461 reviews)
The price is £100
includes taxes & fees
22 Mar - 23 Mar

Hampton Inn Spartanburg-North I-85
Hampton Inn Spartanburg-North I-85Spartanburg
8.6 out of 10, Excellent, (1,000 reviews)
The price is £67
includes taxes & fees
29 Mar - 30 Mar

Holiday Inn Express & Suites Clemson by IHG
Holiday Inn Express & Suites Clemson by IHGClemson
8.8 out of 10, Excellent, (958 reviews)
The price is £103
includes taxes & fees
5 Apr - 6 Apr

Inn @ Clemson
Inn @ ClemsonClemson
8.2 out of 10, Very good, (1,002 reviews)
The price is £67
includes taxes & fees
23 Mar - 24 Mar

Best Western Spartanburg Northwest
Best Western Spartanburg NorthwestSpartanburg
8.2 out of 10, Very good, (851 reviews)
The price is £70
includes taxes & fees
21 Mar - 22 Mar

Spartanburg Marriott
Spartanburg MarriottSpartanburg
8.6 out of 10, Excellent, (1,001 reviews)
The price is £99
includes taxes & fees
29 Mar - 30 Mar

Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (857 reviews)
The price is £77
includes taxes & fees
22 Mar - 23 Mar

Woodspring Suites Greenville Airport
Woodspring Suites Greenville AirportGreenville
8.2 out of 10, Very good, (353 reviews)
The price is £66
includes taxes & fees
17 Mar - 18 Mar

Comfort Suites At WestGate Mall
Comfort Suites At WestGate MallSpartanburg
8.2 out of 10, Very good, (1,006 reviews)
The price is £76
includes taxes & fees
22 Mar - 23 Mar

AC Hotel by Marriott Spartanburg
AC Hotel by Marriott SpartanburgSpartanburg
9.4 out of 10, Exceptional, (612 reviews)
The price is £125
includes taxes & fees
22 Mar - 23 Mar

Holiday Inn Greenville - Woodruff Road by IHG
Holiday Inn Greenville - Woodruff Road by IHGGreenville
8.6 out of 10, Excellent, (679 reviews)
The price is £106
includes taxes & fees
22 Mar - 23 Mar

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
Hampton Inn & Suites Spartanburg-I-26-Westgate MallSpartanburg
8.6 out of 10, Excellent, (1,000 reviews)
The price is £93
includes taxes & fees
22 Mar - 23 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (66 reviews)
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Stay near popular Southeastern United States attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews

Hyatt Place Greenville/Haywood
10/10 Excellent
More cheap stays in Upstate South Carolina

Urban Boutique Hotel, BW Signature Collection
536 Wade Hampton Blvd Greenville SC
The price is £54 per night from 29 Mar to 30 Mar
£54
29 Mar - 30 Mar
includes taxes & fees
8/10 Very Good! (973 reviews)
Hotels in Upstate South Carolina with star rating

4 Star Hotels
11 properties
Explore a world of travel with Expedia
- Brookhaven Hotels
- Chick Springs Hotels
- Colonel Elias Earle Historic District Hotels
- Hotels near Discovery Island Water Park
- Hotels near Donaldson Center
- Duncan Hotels
- Easley Hotels
- Hotels near Eugene Stone Soccer Stadium
- Fountain Inn Hotels
- Hotels near Frankie's Fun Park
- Gay-Friendly Hotels in Green Avenue
- Capsule Hotels in Greenville
- Caravan Parks in Greenville
- Condo Rentals in Greenville
- Hotels near Greenville Downtown
- Hotels with Connecting Rooms in Greenville Downtown
- Pet-Friendly Hotels in Greenville Downtown
- Greenville Downtown Hotels
- Beach Resorts & in Greenville
- Boutique Hotels in Greenville
- Cheap Hotels in Greenville
- Family-Friendly Hotels in Greenville
- Gay-Friendly Hotels in Greenville
- Historic Hotels in Greenville
- Hotels Suites in Greenville
- Hotels with Gym in Greenville
- Hotels with Balcony in Greenville
- Hotels with Hot Tubs in Greenville
- Hotels with Indoor Pools in Greenville
- Luxury Hotels in Greenville
- Motel 6 Hotels in Greenville
- Pet-Friendly Hotels in Greenville
- Spa Hotels in Greenville
- Greenville Hotels
- Greenville - Spartanburg Hotels
- Hotels near Greenville-Spartanburg Intl.
- Greer Hotels
- Mauldin Hotels
- Hotels near Patewood Memorial Hospital
- Pelzer Hotels
- Pettigru Street Historic District Hotels
- Piedmont Hotels
- Sans Souci Hotels
- Gay-Friendly Hotels in Simpsonville
- Hotels with Indoor Pools in Simpsonville
- Simpsonville Hotels
- Taylors Hotels
- Travelers Rest Hotels
- Wade Hampton Hotels
- Welcome Hotels
- West End Hotels
- Williamston Hotels
- Woodside Cotton Mill Village Historic District Hotels
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