
Upstate South Carolina Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Upstate South Carolina Holiday
Leave the planning to us with a Upstate South Carolina holiday package. With everything arranged before you go, the only thing left for you to do is relax and experience this destination's culture and beauty. With so much to see on a trip to Upstate South Carolina, it can be difficult to know where to begin. Kick off your travels in Greenville at Falls Park on the Reedy and Bon Secours Wellness Arena — two much-loved attractions here. Another city worth adding to your itinerary is Spartanburg. Don't miss WestGate Mall and Tyger River Park. Expedia has flights, hotels and everything else you need to help you curate your own tailored Upstate South Carolina holiday today.
Where to stay in Upstate South Carolina

Greenville Downtown
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charlotte-Douglas Intl. Airport (CLT) |
Top hotels in Upstate South Carolina

Hilton Greenville
It was ok
Reviewed on 1 May 2026

Embassy Suites Greenville Golf Resort & Conference Center
We are being a charged for a stay that never happened, even with proof of cancellation!
Reviewed on 30 Apr 2026

Hyatt Place Greenville/Haywood
Parking easy, room very clean and updated and friendly staff. Elevators slow but that’s okay. Breakfast was not that great unfortunately.
Reviewed on 30 Apr 2026
Popular places to visit

Fred W. Symmes Chapel
You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.

Devils Fork State Park
You can take time to visit Devils Fork State Park during your travels to Salem. Wander the lakeside or discover the area's mountain views.

Tyger River Park
Catch an event at Tyger River Park during your trip to Spartanburg. While in this family-friendly area, you can savour the top-notch restaurants.
What to do in Upstate South Carolina

Paranormal Walking Tour by Greenville Ghost Tours
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Discovery Island Water Park
- Hotels near Donaldson Center
- Hotels near Frankie's Fun Park
- Gay-Friendly Hotels in Green Avenue
- Capsule Hotels in Greenville
- Caravan Parks in Greenville
- Condo Rentals in Greenville
- Hotels near Greenville Downtown
- Hotels with Connecting Rooms in Greenville Downtown
- Pet-Friendly Hotels in Greenville Downtown
- Greenville Downtown Hotels
- Beach Resorts & in Greenville
- Boutique Hotels in Greenville
- Cheap Hotels in Greenville
- Gay-Friendly Hotels in Greenville
- Hotels Suites in Greenville
- Hotels with Indoor Pools in Greenville
- Luxury Hotels in Greenville
- Motel 6 Hotels in Greenville
- Pet-Friendly Hotels in Greenville
- Spa Hotels in Greenville
- Greenville Hotels
- Mauldin Hotels
- Hotels near Patewood Memorial Hospital
- Pettigru Street Historic District Hotels
- Gay-Friendly Hotels in Simpsonville
- Hotels with Indoor Pools in Simpsonville
- Simpsonville Hotels
- West End Hotels
- Flights to Greenville
- Flights to Simpsonville
- Flights from Donaldson Center
- Flights from Greenville Downtown
- Flights from Greenville
- Flights from Dunean
- Flights from Simpsonville
- Flights from Augusta (AGS) to Greenville (GMU)
- Flights from Anderson (AND) to Greenville (GMU)
- Flights from Atlanta (ATL) to Greenville (GMU)
- Flights from Clemson (CEU) to Greenville (GDC)
- Flights from Washington (DCA) to Greenville (GDC)
- Flights from Detroit (DTW) to Greenville (GMU)
- Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GMU)
- Flights from Gaithersburg (GAI) to Greenville (GMU)
- Flights from Greenwood (GRD) to Greenville (GMU)
- Flights from Hagerstown (HGR) to Greenville (GMU)
- Flights from Hong Kong (HKG) to Greenville (GDC)
- Flights from Islip (ISP) to Greenville (GMU)
- Flights from Jacksonville (JAX) to Greenville (GMU)
- Flights from Las Vegas (LAS) to Greenville (GMU)
- Flights from Los Angeles (LAX) to Greenville (GMU)
- Flights from Pickens (LQK) to Greenville (GDC)
- Flights from Morgantown (MGW) to Greenville (GMU)
- Flights from Dayton (MGY) to Greenville (GMU)
- Flights from Madison (MSN) to Greenville (GDC)
- Flights from New Orleans (MSY) to Greenville (GMU)
- Flights from Paris (PAR) to Greenville (GDC)
- Flights from Rocky Mount (RWI) to Greenville (GMU)
- Flights from Louisville (SDF) to Greenville (GMU)
- Flights from St. Louis (STL) to Greenville (GMU)
- Flights from Taipei (TPE) to Greenville (GDC)
- Anderson Holidays
- Bi Lo Center
- Central Holidays
- Clemson Holidays
- Discovery Island Water Park
- Duncan Holidays
- First Presbyterian Church
- Frankie's Fun Park
- Fred W. Symmes Chapel
- Greenville - Spartanburg Holidays
- Greenville Holidays
- Visit Greenville
- Historic Greer Depot
- Honea Path Holidays
- Inman Holidays
- Laurens County Courthouse
- Laurens Holidays
- North Grove Medical Park
- Patewood Memorial Hospital
- Simpsonville Holidays
- Southern Shops Holidays
- Spartanburg Expo Center
- Spartanburg Holidays
- Taylors Holidays
- The Price House
- Travelers Rest Holidays
- Tyger-10 Nature Park
- Tyger River Park
- University Square Shopping Center
- Wade Hampton Mall Shopping Center
- Warehouse Theatre
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
















