Title: Cheap Car Hire in Upstate South Carolina, USA - Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/144669/e945b35d-16b4-408c-818b-68622e164446.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Upstate South Carolina, USA ## Search and Compare from Car Companies in Upstate South Carolina Photo by RVLuckyorWhat ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Upstate South Carolina \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Upstate South Carolina, South Carolina, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Upstate%20South%20Carolina,%20South%20Carolina,%20United%20States%20of%20America&dpln=6057939&date1=23/12/2025&date2=25/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Upstate South Carolina, South Carolina, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Upstate%20South%20Carolina,%20South%20Carolina,%20United%20States%20of%20America&dpln=6057939&date1=23/12/2025&date2=25/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Upstate South Carolina, South Carolina, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Upstate%20South%20Carolina,%20South%20Carolina,%20United%20States%20of%20America&dpln=6057939&date1=23/12/2025&date2=25/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Upstate South Carolina, South Carolina, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Upstate%20South%20Carolina,%20South%20Carolina,%20United%20States%20of%20America&dpln=6057939&date1=23/12/2025&date2=25/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in Upstate South Carolina [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Upstate%20South%20Carolina,%20South%20Carolina,%20United%20States%20of%20America&dpln=6057939&date1=23/12/2025&date2=25/12/2025&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### What happens if I need to cancel my Upstate South Carolina car reservation? ### What types of cars can I rent in Upstate South Carolina? ### How do I find the best car hire deals in Upstate South Carolina with Expedia? ### How old do you have to be to rent a car in Upstate South Carolina? ### What do you need to rent a car in Upstate South Carolina? ### Can I hire a car for a month or longer in Upstate South Carolina? ### Where can I find a Upstate South Carolina hire car if I am younger than 25? ### Why should I rent a Upstate South Carolina car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [Hotels near Discovery Island Water Park ](https://www.expedia.co.uk/Discovery-Island-Water-Park-Hotels.0-l553248621532656705-0.Travel-Guide-Filter-Hotels) - [Hotels near Donaldson Center ](https://www.expedia.co.uk/Donaldson-Center-Airport-Hotels.0-aGDC-0.Travel-Guide-Filter-Hotels) - [Hotels near Frankie's Fun Park ](https://www.expedia.co.uk/Frankies-Fun-Park-Hotels.0-l553248621532656780-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Green Avenue ](https://www.expedia.co.uk/Green-Avenue-Greenville-Hotels-Gay-Friendly-Hotel.0-n553248635976476062-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Capsule Hotels in Greenville ](https://www.expedia.co.uk/Greenville-Capsule-Hotels.d1388-aaCapsuleHotels.Travel-Guide-Accommodation) - [Caravan Parks in Greenville ](https://www.expedia.co.uk/Greenville-Caravan-Parks.d1388-aaCaravanParks.Travel-Guide-Accommodation) - [Hotels near Greenville Downtown ](https://www.expedia.co.uk/Greenville-Downtown-Airport-Hotels.0-aGMU-0.Travel-Guide-Filter-Hotels) - 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