Title: TOP Upstate South Carolina Spa Hotels for 2025 - Spas in Upstate South Carolina, SC | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![Greenville - Spartanburg which includes views, tranquil scenes and mountains](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Upstate South Carolina, SC ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Spa Hotels Tonight [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-10-11&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-10-12&endDate=2025-10-13&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Spa Hotels ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/24c29149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/4694c80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique Travelers Rest 9.6/10 Exceptional (30) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." £378 includes taxes & fees 29 Oct - 30 Oct [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Couples treatment room(s), body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/aa0a358b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d57fd5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/6b940d91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness Greenville 9.8/10 Exceptional (600) "amazing place and great visit to area" £157 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-72054b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/0671c5e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection Greenville Downtown 9.6/10 Exceptional (391) "Beautiful hotel with views of the Reedy River and Falls. " £246 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/0fc978a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Room, 1 King Bed with Sofa bed | 1 bedroom, premium bedding, memory-foam beds, individually decorated](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/2f186f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Cabin, Non Smoking | Private kitchen | Full-sized fridge, microwave, coffee/tea maker, high chair](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/ed481a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, 1 King Bed with Sofa bed, Slope side | Terrace/patio](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/24255478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SKYLARANNA Resort & Spa Hendersonville 8.2/10 Very good (324) "Quiet, close to I-26, and nice outdoor restaurant on premises with good food. " £108 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Asheville-Hotels-Skylaranna-Hotel-And-Resort.h54524318.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/1dc0c9a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/d5dd3f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/7ceab56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/ba98f491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Echo Mountain Inn Hendersonville 9.0/10 Wonderful (538) "We loved our stay! A truly special place!!" £96 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/Asheville-Hotels-Echo-Mountain-Inn.h13209511.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/bf5bcc5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/3d120676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/3c755149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/20aae6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kingwood Resort Clayton 8.0/10 Very good (419) "the staff were very friendly! " £135 includes taxes & fees 21 Oct - 22 Oct [](https://www.expedia.co.uk/Helen-Hotels-Kingwood-Resort.h921807.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/8063695a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, 2 Bedrooms (The Lady Anne Room) | Premium bedding, memory-foam beds, individually decorated](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/a490469b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, DVD player](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/8974dec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/b49fc2c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Morgan and Wells B&B Shelby 9.6/10 Exceptional (88) "Always excellent to stay at M and W!!" £126 includes taxes & fees 11 Nov - 12 Nov [](https://www.expedia.co.uk/Shelby-Hotels-Morgan-And-Wells-BB.h11043190.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/70dd5eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dock](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/07befbdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/ceeaab49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/ca7d3507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greystone Inn Lake Toxaway 9.4/10 Exceptional (84) "Most beautiful quiet and peaceful old guest home. " £275 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Highlands-Hotels-Greystone-Inn.h23208596.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/90000000/89260000/89255200/89255189/0f9ba89d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/90000000/89260000/89255200/89255189/e6be9b0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hiking](https://images.trvl-media.com/lodging/90000000/89260000/89255200/89255189/f8aab2c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89260000/89255200/89255189/75245eae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mountain Loft Resort Lake Lure 8.4/10 Very good (9) "Loved our stay at Rumbling Bald! The amenities at the resort are amazing. We were so impressed. Can’t wait to come back. " [](https://www.expedia.co.uk/Lake-Lure-Hotels-Mountain-Loft-Resort-Unit-3.h89255189.Hotel-Information) ![Deep-tissue massages, sports massages, 1 treatment room](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/13291cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/378c645d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/8706e1c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (09 Witham Point Room) | 1 bedroom, individually decorated, individually furnished](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/775ce741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Rabun Hotel & Restaurant Lakemont 8.6/10 Excellent (632) "It’s a quiet peaceful place to stay with helpful staff." £128 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/Helen-Hotels-Lake-Rabun-Hotel-Restaurant.h7416620.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-25&endDate=2025-10-26®ionId=6057939&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Upstate South Carolina ### Top Upstate South Carolina attractions for a relaxing vacation Upstate South Carolina offers a delightful blend of relaxation and adventure, perfect for travellers seeking luxurious spa experiences. Begin your journey in Greenville, where the stunning Falls Park on the Reedy presents a tranquil escape with its picturesque waterfalls and serene walking trails, ideal for unwinding after a day of pampering. Just a short drive away, the vibrant Downtown Spartanburg is home to the Chapman Cultural Centre, where you can immerse yourself in local art and history, adding a cultural touch to your stay. For outdoor enthusiasts, the scenic beauty of Table Rock State Park invites you to hike its trails, offering breathtaking views that rejuvenate the spirit. If you’re keen on a unique experience, consider the nearby Lake Hartwell, where you can indulge in a lakeside retreat, complete with opportunities for kayaking and fishing, followed by spa treatments that soothe your body and mind. For accommodation, the charming towns of Greenville and Spartanburg feature hotels spa services, where attentive staff cater to your every need, ensuring a pampered stay that leaves you refreshed and revitalised. ## Top Upstate South Carolina Hotel Reviews ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Awesome " [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "I enjoyed my stay here. It was very clean and cozy. I will make another stay here, if available for my next travel. Thank you! " [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Everything is super nice and clean" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "I loved my stay here! The rooms are spotless, the staff are so warm and welcoming, and the location is awesome with lots of restaurants and shops nearby. The price is such a great deal—you get free breakfast, dinner, AND three drinks every night! Can’t recommend it enough!" [](https://expedia.co.uk/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Hotels with a View in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-A-View.0-0-d242-thotelwithaview.Hotel-Filter-Destinations) - [Hotels with Air Conditioning in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-Air-Conditioning.0-0-d242-thotelwithairconditioning.Hotel-Filter-Destinations) - [Hotels with Breakfast in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-Breakfast.0-0-d242-thotelwithbreakfast.Hotel-Filter-Destinations) - [Hotels with Connecting Rooms in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-Connecting-Rooms.0-0-d242-thotelwithconnectingrooms.Hotel-Filter-Destinations) - [Hotels with Early Check-in in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-Early-Check-In.0-0-d242-thotelwithearlycheckin.Hotel-Filter-Destinations) - 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[Family-Friendly Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Family-Friendly-Hotel.0-0-d1388-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Gay-Friendly-Hotel.0-0-d1388-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Historic-Hotel.0-0-d1388-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels Suites in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Suites.0-0-d1388-thotelsuites.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-A-Bar.0-0-d1388-thotelwithabar.Travel-Guide-Filter-Hotels) - [Hotels with Babysitting Services in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Babysitting-Services.0-0-d1388-thotelwithbabysittingservices.Travel-Guide-Filter-Hotels) - [Hotels with Parking in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Free-Parking.0-0-d1388-thotelwithfreeparking.Travel-Guide-Filter-Hotels) - [Hotels with Gym in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Gym.0-0-d1388-thotelwithgym.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Service in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Laundry-Service.0-0-d1388-thotelwithlaundryservice.Travel-Guide-Filter-Hotels) - [Hotels with Parking in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Parking.0-0-d1388-thotelwithparking.Travel-Guide-Filter-Hotels) - [Hotels with Room Service in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Room-Service.0-0-d1388-thotelwithroomservice.Travel-Guide-Filter-Hotels) - [Hotels with Balcony in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotels-With-Balcony.0-0-d1388-tHotelswithBalcony.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotels-With-Hot-Tubs.0-0-d1388-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotels-With-Indoor-Pools.0-0-d1388-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Lakeside Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Lakeside-Hotel.0-0-d1388-tlakesidehotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Luxury-Hotel.0-0-d1388-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Motel-6.0-0-d1388--bMotel6.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Pet-Friendly-Hotel.0-0-d1388-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Riverside Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Riverside-Hotel.0-0-d1388-triversidehotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Romantic-Hotel.0-0-d1388-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Spa-Hotels.0-0-d1388-tSpaHotels.Travel-Guide-Filter-Hotels) - [Greenville Hotels](https://www.expedia.co.uk/Greenville-Hotels.d1388.Travel-Guide-Hotels) - [Mauldin Hotels](https://www.expedia.co.uk/Mauldin-Hotels.d183944.Travel-Guide-Hotels) - [Hotels near Patewood Memorial Hospital](https://www.expedia.co.uk/Patewood-Memorial-Hospital-Hotels.0-l6130783-0.Travel-Guide-Filter-Hotels) - [Pettigru Street Historic District Hotels](https://www.expedia.co.uk/Pettigru-Street-Historic-District-Greenville-Hotels.0-n6348167-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Simpsonville](https://www.expedia.co.uk/Simpsonville-Hotels-Gay-Friendly-Hotel.0-0-d6239-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Simpsonville](https://www.expedia.co.uk/Simpsonville-Hotels-Hotels-With-Indoor-Pools.0-0-d6239-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Simpsonville Hotels](https://www.expedia.co.uk/Simpsonville-Hotels.d6239.Travel-Guide-Hotels) - [West End Hotels](https://www.expedia.co.uk/West-End-Greenville-Hotels.0-n6348163-0.Travel-Guide-Filter-Hotels) - [Flights to Greenville](https://www.expedia.co.uk/Cheap-Flights-To-Greenville.d1388.Travel-Guide-Flights) - [Flights to Simpsonville](https://www.expedia.co.uk/Cheap-Flights-To-Simpsonville.d6239.Travel-Guide-Flights) - [Flights from Donaldson Center](https://www.expedia.co.uk/lp/airports/gdc/flights-from-donaldson-center-airport) - [Flights from Greenville Downtown](https://www.expedia.co.uk/lp/airports/gmu/flights-from-greenville-downtown-airport) - [Flights from Greenville](https://www.expedia.co.uk/lp/flights/1388/flights-from-greenville) - [Flights from Dunean](https://www.expedia.co.uk/lp/flights/553248634999354841/flights-from-dunean) - [Flights from Simpsonville](https://www.expedia.co.uk/lp/flights/6239/flights-from-simpsonville) - [Flights from Augusta (AGS) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/ags/gmu/augusta-to-greenville) - [Flights from Anderson (AND) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/and/gmu/anderson-to-greenville) - [Flights from Atlanta (ATL) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/atl/gmu/atlanta-to-greenville) - [Flights from Clemson (CEU) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/ceu/gdc/clemson-to-greenville) - [Flights from Washington (DCA) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/dca/gdc/washington-to-greenville) - [Flights from Detroit (DTW) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/dtw/gmu/detroit-to-greenville) - [Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/ewr/gmu/newark-liberty-intl-airport-to-greenville) - [Flights from Gaithersburg (GAI) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/gai/gmu/gaithersburg-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/grd/gmu/greenwood-to-greenville) - [Flights from Hagerstown (HGR) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/hgr/gmu/hagerstown-to-greenville) - [Flights from Hong Kong (HKG) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/hkg/gdc/hong-kong-to-greenville) - [Flights from Islip (ISP) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/isp/gmu/islip-to-greenville) - [Flights from Jacksonville (JAX) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/jax/gmu/jacksonville-to-greenville) - [Flights from Las Vegas (LAS) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/las/gmu/las-vegas-to-greenville) - [Flights from Los Angeles (LAX) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/lax/gmu/los-angeles-to-greenville) - [Flights from Pickens (LQK) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/lqk/gdc/pickens-to-greenville) - [Flights from Morgantown (MGW) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/mgw/gmu/morgantown-to-greenville) - [Flights from Dayton (MGY) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/mgy/gmu/dayton-to-greenville) - [Flights from Madison (MSN) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/msn/gdc/madison-to-greenville) - [Flights from New Orleans (MSY) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/msy/gmu/new-orleans-to-greenville) - [Flights from Paris (PAR) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/par/gdc/paris-to-greenville) - [Flights from Rocky Mount (RWI) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/rwi/gmu/rocky-mount-to-greenville) - [Flights from Louisville (SDF) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/sdf/gmu/louisville-to-greenville) - [Flights from St. Louis (STL) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/stl/gmu/st-louis-to-greenville) - [Flights from Taipei (TPE) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/tpe/gdc/taipei-to-greenville) - [Discovery Island Water Park](https://www.expedia.co.uk/Discovery-Island-Water-Park-Greenville.d553248621532656705.Attraction) - [Frankie's Fun Park](https://www.expedia.co.uk/Frankies-Fun-Park-Greenville.d553248621532656780.Attraction) - [Greenville Holidays](https://www.expedia.co.uk/Greenville.d1388.Holidays-City-Breaks) - [Visit Greenville](https://www.expedia.co.uk/Greenville.dx1388) - [Patewood Memorial Hospital](https://www.expedia.co.uk/Patewood-Memorial-Hospital-Greenville.d6130783.Attraction) - [Simpsonville Holidays](https://www.expedia.co.uk/Simpsonville.d6239.Holidays-City-Breaks) - [Warehouse Theatre](https://www.expedia.co.uk/Warehouse-Theatre-Greenville-Downtown.d553248621532656721.Attraction) - [Car hire Greenville](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Greenville.d1388.Car-Hire-Guide) - [Car hire Simpsonville](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Simpsonville.d6239.Car-Hire-Guide) - [Gantt Holiday Rentals](https://www.expedia.co.uk/Gantt-Holiday-Rentals.d553248634999376437.Travel-Guide-HolidayRentals) - [Greenville Holiday Rentals](https://www.expedia.co.uk/Greenville-Holiday-Rentals.d1388.Travel-Guide-HolidayRentals) - [Mauldin Holiday Rentals](https://www.expedia.co.uk/Mauldin-Holiday-Rentals.d183944.Travel-Guide-HolidayRentals) - [Things to do in Greenville](https://www.expedia.co.uk/Things-To-Do-In-Greenville.d1388.Travel-Guide-Activities) - [Things to do in Simpsonville](https://www.expedia.co.uk/Things-To-Do-In-Simpsonville.d6239.Travel-Guide-Activities) - [Book Spa Hotels in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Spa-Hotel.0-0-d6057939-tSpaHotel.Travel-Guide-Filter-Hotels)