A bench, a bicycle, and a lake surrounded by trees.

Find Spa Hotels in Upstate South Carolina, SC

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Check availability on Upstate South Carolina Spa Hotels

Tonight
24 Oct - 25 Oct
Tomorrow
25 Oct - 26 Oct
Next weekend
30 Oct - 1 Nov
In two weeks
6 Nov - 8 Nov

Our top choices for Upstate South Carolina hotels with a spa

A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.
A modern interior with a large window, a chandelier, a dining area, and a hallway leading to a door.
A cozy lounge area with leather armchairs, a central table, and a fireplace.
A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.

1. Hotel Hartness

Hotel Hartness
Greenville
  • Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
£164
includes taxes & fees
25 Oct - 26 Oct
Hotel Hartness
A spa room with two beds, a mural, and a reception desk.
A modern interior with a fireplace, plush seating, and a stone accent wall.
A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.
A modern interior with a stone fireplace, seating areas, and a unique ceiling design.

2. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
  • Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
£296
includes taxes & fees
15 Nov - 16 Nov
Grand Bohemian Lodge Greenville, Autograph Collection
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A bar with a large window view of mountains and a chandelier.
A swimming pool with lounge chairs and a building with balconies.
A spacious room with wooden beams, a large chandelier, and a cozy seating area with orange chairs and a white sofa.

3. Hotel Domestique

Hotel Domestique
Travelers Rest
  • Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
£344
includes taxes & fees
25 Oct - 26 Oct
Hotel Domestique
A two-story house with a covered porch, a front entrance, and a landscaped garden.
Interior
Exterior
A hotel room with a large bed, a fireplace, a television, and a ceiling fan.

4. Bed & Breakfast on Tiffany Hill

Bed & Breakfast on Tiffany Hill
Mills River
£247
includes taxes & fees
8 Nov - 9 Nov
Bed & Breakfast on Tiffany Hill
A hotel room with two beds, wooden walls, and a window.
A cozy wooden cabin bedroom with a bed, a wooden table, a chair, and a window with curtains.
A rustic wooden room with a wooden door, a small table with a lamp, a chair, and a window with curtains.
A rustic cabin with a covered porch, surrounded by trees.

5. Lake Rabun Hotel & Restaurant

Lake Rabun Hotel & Restaurant
Lakemont
  • Soak in therapeutic massages and mountain tranquility at this historic boutique hotel nestled near Tallulah Gorge State Park.
£107
includes taxes & fees
25 Oct - 26 Oct
Lake Rabun Hotel & Restaurant
A hotel room with two beds, a desk, a chair, a mirror, and a window with curtains.
A dining area with checkered flooring, multiple tables and chairs, and a decorative cabinet with various items.
A modern bathroom with a glass shower enclosure, a white toilet, and a sink with a mirror above it.
A covered porch with a view of a street, two potted plants, and an American flag.

6. 1898 Waverly Inn

1898 Waverly Inn
Hendersonville
  • Experience spa bliss at this charming B&B with relaxing massage treatment rooms and attentive staff who ensure a rejuvenating stay.
£123
includes taxes & fees
27 Oct - 28 Oct
1898 Waverly Inn
A reception desk with a logo, a Buddha statue, a vase, and a door labeled 'EMPLOYEES ONLY'.
A bedroom with a bed, a nightstand, a lamp, and a view of a balcony with outdoor furniture.
A breakfast plate with eggs, bacon, and fries, a coffee cup, and a glass of water on a table with a view of a pool and mountains.
A bedroom with a bed, a nightstand, a window with curtains, and a view of the outside.

7. SKYLARANNA Resort & Spa

SKYLARANNA Resort & Spa
Hendersonville
  • Rejuvenate in a mountain spa retreat with 3 dedicated treatment rooms, hot tubs, and aromatherapy services along a scenic river.
£138
includes taxes & fees
25 Oct - 26 Oct
SKYLARANNA Resort & Spa
A hotel room with a bed, a bedside lamp, and a small table with candles.
A spacious dining area with multiple tables and chairs, large windows, and ornate chandeliers.
A lakeside lodge with outdoor seating and string lights.
A stone staircase leading to a house with a stone chimney and a small glass door.

8. Greystone Inn

Greystone Inn
Lake Toxaway
  • Soak in mountain views at this lakeside retreat with couples' spa treatment rooms, yoga classes, and deep-tissue massages.
£300
includes taxes & fees
23 Nov - 24 Nov
Greystone Inn
A two-story wooden cabin with a balcony, a swimming pool, and a deck area.
A cozy room with a bed, a chair, a tray with snacks and wine, and a view of the outdoors.
A covered porch with rocking chairs and a small table with flowers.
A wooden interior with tables and chairs, a fireplace, and a stone wall.

9. Glen-Ella Springs Hotel & Restaurant

Glen-Ella Springs Hotel & Restaurant
Clarkesville
  • Relaxing country retreat with in-room massages and a serene garden setting for a rejuvenating spa experience.
£180
includes taxes & fees
26 Oct - 27 Oct
Glen-Ella Springs Hotel & Restaurant
A round table set for four with wicker chairs, a white tablecloth, and a view of a forested area through large windows.
A bedroom with two beds, wooden headboard panels, and a window with a view.
A cozy living room with a large window, a fireplace, and various plants.
A bathroom with a shower area, a toilet, and a sink.

10. Sylvan Falls Mill B&B

Sylvan Falls Mill B&B
Rabun Gap
  • Serene mountain retreat offers restorative massages in a garden setting, steps away from Chattahoochee National Forest.
£176
includes taxes & fees
28 Oct - 29 Oct
Sylvan Falls Mill B&B
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Choose what matters most at spa hotels in Upstate South Carolina

Pool
Breakfast included
Hot tub
4 stars
5 stars

Find out more about Upstate South Carolina

Top Upstate South Carolina attractions for a relaxing vacation

Upstate South Carolina offers a delightful blend of relaxation and adventure, perfect for travellers seeking luxurious spa experiences. Begin your journey in Greenville, where the stunning Falls Park on the Reedy presents a tranquil escape with its picturesque waterfalls and serene walking trails, ideal for unwinding after a day of pampering. Just a short drive away, the vibrant Downtown Spartanburg is home to the Chapman Cultural Centre, where you can immerse yourself in local art and history, adding a cultural touch to your stay. For outdoor enthusiasts, the scenic beauty of Table Rock State Park invites you to hike its trails, offering breathtaking views that rejuvenate the spirit. If you’re keen on a unique experience, consider the nearby Lake Hartwell, where you can indulge in a lakeside retreat, complete with opportunities for kayaking and fishing, followed by spa treatments that soothe your body and mind. For accommodation, the charming towns of Greenville and Spartanburg feature hotels spa services, where attentive staff cater to your every need, ensuring a pampered stay that leaves you refreshed and revitalised.

Top Upstate South Carolina Hotel Reviews

Hilton Greenville

Hilton Greenville

10/10 Excellent
"Location is great for getting to/from downtown area"
William 1-night trip
Posted 9 hours ago
Hilton Greenville
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"My stay at Embassy Suites was great. My room was clean the floor level I requested was very convenient the staff was helpful and gracious. the area was nice with near by stores surrounding the area, Overall it was great and I would definitely come back."
Jeanette 1-night trip
Posted 11 hours ago
Embassy Suites Greenville Golf Resort & Conference Center

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