Title: TOP Upstate South Carolina Spa Hotels for 2026 - Spas in Upstate South Carolina, SC | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix ![](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Spa Hotels Tonight [15 Jan - 16 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-15&endDate=2026-01-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [16 Jan - 17 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-16&endDate=2026-01-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina hotels with a spa ![Courtyard](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/96abb166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/b8d82b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) Travelers Rest 9.8/10 Exceptional (31 reviews) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck £225 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-72054b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection [](https://www.expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) Greenville Downtown 9.6/10 Exceptional (436 reviews) "Awesome place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ailen £192 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Couples treatment room(s), body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/0d84d9ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Greenville 9.8/10 Exceptional (639 reviews) "The hotel was clean staff was amazing room was outstanding." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clifford £156 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Standard Studio, 1 King Bed with Sofa bed, Slope side | Terrace/patio](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/24255478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/aa1281a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, memory-foam beds, individually decorated](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/98196a96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Cabin, Non Smoking | Premium bedding, memory-foam beds, individually decorated](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/51fa3dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SKYLARANNA Resort & Spa [](https://www.expedia.co.uk/Asheville-Hotels-Skylaranna-Hotel-And-Resort.h54524318.Hotel-Information) Hendersonville 8.2/10 Very good (349 reviews) "The staff was amazing! Fast resolution to any problem or mishap, with very kind and sincere generosity. We had a wonderful stay and loved the rooms view that we had. Perfect stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charity £82 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Asheville-Hotels-Skylaranna-Hotel-And-Resort.h54524318.Hotel-Information) ![Couples treatment room(s), hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/b51de8d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/2cd775cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/bedbaa04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/9fc2aad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Lure Inn & Spa [](https://www.expedia.co.uk/Lake-Lure-Hotels-Lake-Lure-Inn-And-Spa.h107204500.Hotel-Information) Lake Lure 8.4/10 Very good (94 reviews) "Love the old charm of this inn." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer [](https://www.expedia.co.uk/Lake-Lure-Hotels-Lake-Lure-Inn-And-Spa.h107204500.Hotel-Information) ![Deep-tissue massages, sports massages, 1 treatment room](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/13291cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (09 Witham Point Room) | Individually decorated, individually furnished, iron/ironing board](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/c94345b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/36baf331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/b1815eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Rabun Hotel & Restaurant [](https://www.expedia.co.uk/Helen-Hotels-Lake-Rabun-Hotel-Restaurant.h7416620.Hotel-Information) Lakemont 8.6/10 Excellent (646 reviews) "This was a perfect get-away spot and we thoroughly enjoyed our time here!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Meredith £100 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Helen-Hotels-Lake-Rabun-Hotel-Restaurant.h7416620.Hotel-Information) ![1 treatment room, massages](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/7f348ae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/1fcea098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/1b011f9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/5f74fd6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1898 Waverly Inn [](https://www.expedia.co.uk/Asheville-Hotels-1898-Waverly-Inn.h898978.Hotel-Information) Hendersonville 9.4/10 Exceptional (291 reviews) "Everything - from check in to check out was excellent! Evening wine and breakfast was delicious!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy £103 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Asheville-Hotels-1898-Waverly-Inn.h898978.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/c44295fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/3c755149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/20aae6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/1000000/930000/921900/921807/071b97fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kingwood Resort [](https://www.expedia.co.uk/Helen-Hotels-Kingwood-Resort.h921807.Hotel-Information) Clayton 8.0/10 Very good (424 reviews) "the staff were very friendly! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jossue £151 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Helen-Hotels-Kingwood-Resort.h921807.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/16000000/15830000/15826000/15825932/ff050b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/16000000/15830000/15826000/15825932/4cb33cd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/16000000/15830000/15826000/15825932/w643h488x7y6-040c1855.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/16000000/15830000/15826000/15825932/w796h532x0y0-55144a49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sylvan Falls Mill B&B [](https://www.expedia.co.uk/Helen-Hotels-Sylvan-Falls-Mill-BB.h15825932.Hotel-Information) Rabun Gap 9.6/10 Exceptional (73 reviews) "Linda and Mike were outstanding hosts and welcoming to us. They were accommodating to special diet needs, and anxious to meet our requests. Food was delicious, the sitting area was cozy and our room was perfect. If it were possible we’d give 10 stars. Mike us a tour of the mill and a history of the property that made the whole experience fulfilling. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £162 includes taxes & fees 17 Jan - 18 Jan [](https://www.expedia.co.uk/Helen-Hotels-Sylvan-Falls-Mill-BB.h15825932.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/70dd5eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/bb03cfdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/87372292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/0f1b04d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greystone Inn [](https://www.expedia.co.uk/Highlands-Hotels-Greystone-Inn.h23208596.Hotel-Information) Lake Toxaway 9.4/10 Exceptional (86 reviews) "Magnificent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £232 includes taxes & fees 27 Jan - 28 Jan [](https://www.expedia.co.uk/Highlands-Hotels-Greystone-Inn.h23208596.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-30&endDate=2026-01-31®ionId=6057939&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Upstate South Carolina ### Top Upstate South Carolina attractions for a relaxing vacation Upstate South Carolina offers a delightful blend of relaxation and adventure, perfect for travellers seeking luxurious spa experiences. Begin your journey in Greenville, where the stunning Falls Park on the Reedy presents a tranquil escape with its picturesque waterfalls and serene walking trails, ideal for unwinding after a day of pampering. Just a short drive away, the vibrant Downtown Spartanburg is home to the Chapman Cultural Centre, where you can immerse yourself in local art and history, adding a cultural touch to your stay. For outdoor enthusiasts, the scenic beauty of Table Rock State Park invites you to hike its trails, offering breathtaking views that rejuvenate the spirit. If you’re keen on a unique experience, consider the nearby Lake Hartwell, where you can indulge in a lakeside retreat, complete with opportunities for kayaking and fishing, followed by spa treatments that soothe your body and mind. For accommodation, the charming towns of Greenville and Spartanburg feature hotels spa services, where attentive staff cater to your every need, ensuring a pampered stay that leaves you refreshed and revitalised. ## Top Upstate South Carolina Hotel Reviews ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Convenient and clean" [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "It was wonderful, staff was very nice" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Great service, good price, staff very friendly" [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ## Explore a world of travel with Expedia - 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