Title: TOP Upstate South Carolina Spa Hotels for 2025 - Spas in Upstate South Carolina, SC | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix # Find Spa Hotels in Upstate South Carolina, SC - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Spa Hotels Tonight [25 Nov - 26 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-11-25&endDate=2025-11-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [26 Nov - 27 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-11-26&endDate=2025-11-27&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-11-28&endDate=2025-11-30&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-12-05&endDate=2025-12-07&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Spa Hotels ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/0fc978a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/ae95b708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, 1 King Bed with Sofa bed, Slope side | Terrace/patio](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/24255478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Room, 1 King Bed with Sofa bed | 1 bedroom, premium bedding, memory-foam beds, individually decorated](https://images.trvl-media.com/lodging/55000000/54530000/54524400/54524318/2f186f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SKYLARANNA Resort & Spa Hendersonville 8.2/10 Very good (339) "Quiet, close to I-26, and nice outdoor restaurant on premises with good food. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terry £89 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Asheville-Hotels-Skylaranna-Hotel-And-Resort.h54524318.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/1dc0c9a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/7ceab56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![French Country Room | Individually decorated, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/f665c6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209511/d5dd3f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Echo Mountain Inn Hendersonville 9.0/10 Wonderful (543) "We loved our stay! A truly special place!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dana £98 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Asheville-Hotels-Echo-Mountain-Inn.h13209511.Hotel-Information) ![Deep-tissue massages, sports massages, 1 treatment room](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/13291cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (09 Witham Point Room) | 1 bedroom, individually decorated, individually furnished](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/775ce741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/9945caa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/8000000/7420000/7416700/7416620/378c645d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Rabun Hotel & Restaurant Lakemont 8.6/10 Excellent (641) "This was a perfect get-away spot and we thoroughly enjoyed our time here!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Meredith £104 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Helen-Hotels-Lake-Rabun-Hotel-Restaurant.h7416620.Hotel-Information) ![Couples treatment room(s), body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/aa0a358b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d57fd5de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness Greenville 9.8/10 Exceptional (617) "Excellent staff and facilities. Very clean, comfortable and welcoming atmosphere and very enjoyable stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Craig [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-72054b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/0671c5e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/924dd6ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection Greenville Downtown 9.6/10 Exceptional (409) "The staff were really sweet and responsive. The views from the rooms are breathtaking! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krystal £197 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/24c29149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique Travelers Rest 9.6/10 Exceptional (30) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck £343 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/8063695a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/764f9317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, 2 Bedrooms (The Lady Anne Room) | Premium bedding, memory-foam beds, individually decorated](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/a490469b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/12000000/11050000/11043200/11043190/b49fc2c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Morgan and Wells B&B Shelby 9.6/10 Exceptional (89) "Melanie, the owner and Ronnie, the chef were wonderful hosts!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) SUSAN £129 includes taxes & fees 28 Nov - 29 Nov [](https://www.expedia.co.uk/Shelby-Hotels-Morgan-And-Wells-BB.h11043190.Hotel-Information) ![1 treatment room, massages](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/7f348ae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/cb6f44b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 Queen Bed | Individually decorated, individually furnished, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/f1c0642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/899000/898978/5f74fd6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1898 Waverly Inn Hendersonville 9.4/10 Exceptional (290) "Everything - from check in to check out was excellent! Evening wine and breakfast was delicious!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy £108 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Asheville-Hotels-1898-Waverly-Inn.h898978.Hotel-Information) ![Couples treatment room(s), hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/b51de8d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/9fc2aad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 King Bed (First Floor) | 1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/de3a66af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 King Bed, Non Smoking (Baby's Bungalow) | 1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107210000/107204500/107204500/5584c3e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Lure Inn and Spa Lake Lure 8.4/10 Very good (85) "Great stay. Quite and charming. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £83 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/Lake-Lure-Hotels-Lake-Lure-Inn-And-Spa.h107204500.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2030000/2025000/2024975/cca6f1c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/3000000/2030000/2025000/2024975/cfbd2d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/3000000/2030000/2025000/2024975/a3d268dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/3000000/2030000/2025000/2024975/8ef79078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Glen-Ella Springs Hotel & Restaurant Clarkesville 9.6/10 Exceptional (101) "The entire property yielded pleasant surprises around every corner and the Cottage proved to be a great little corner in which to catch up on the news and play cards. The food and staff service were impeccable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William £170 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Helen-Hotels-Glen-Ella-Springs-Inn.h2024975.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-09&endDate=2025-12-10®ionId=6057939&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_BF_PROMO_6057939) ## Find out more about Upstate South Carolina ### Top Upstate South Carolina attractions for a relaxing vacation Upstate South Carolina offers a delightful blend of relaxation and adventure, perfect for travellers seeking luxurious spa experiences. Begin your journey in Greenville, where the stunning Falls Park on the Reedy presents a tranquil escape with its picturesque waterfalls and serene walking trails, ideal for unwinding after a day of pampering. Just a short drive away, the vibrant Downtown Spartanburg is home to the Chapman Cultural Centre, where you can immerse yourself in local art and history, adding a cultural touch to your stay. For outdoor enthusiasts, the scenic beauty of Table Rock State Park invites you to hike its trails, offering breathtaking views that rejuvenate the spirit. If you’re keen on a unique experience, consider the nearby Lake Hartwell, where you can indulge in a lakeside retreat, complete with opportunities for kayaking and fishing, followed by spa treatments that soothe your body and mind. For accommodation, the charming towns of Greenville and Spartanburg feature hotels spa services, where attentive staff cater to your every need, ensuring a pampered stay that leaves you refreshed and revitalised. ## Top Upstate South Carolina Hotel Reviews ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Great staff, and the room was clean." [](https://expedia.co.uk/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Staff was super friendly and helpful, property was cleaned and on the daily " [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Great hotel" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Clean, convenient, comfortable Large well appointed room " [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ## Explore a world of travel with Expedia - 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[Hotels with Gym in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Gym.0-0-d1388-thotelwithgym.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Service in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Laundry-Service.0-0-d1388-thotelwithlaundryservice.Travel-Guide-Filter-Hotels) - [Hotels with Parking in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Parking.0-0-d1388-thotelwithparking.Travel-Guide-Filter-Hotels) - [Hotels with Room Service in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotel-With-Room-Service.0-0-d1388-thotelwithroomservice.Travel-Guide-Filter-Hotels) - [Hotels with Balcony in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotels-With-Balcony.0-0-d1388-tHotelswithBalcony.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotels-With-Hot-Tubs.0-0-d1388-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Hotels-With-Indoor-Pools.0-0-d1388-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Lakeside Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Lakeside-Hotel.0-0-d1388-tlakesidehotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Luxury-Hotel.0-0-d1388-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Motel-6.0-0-d1388--bMotel6.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Pet-Friendly-Hotel.0-0-d1388-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Riverside Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Riverside-Hotel.0-0-d1388-triversidehotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Romantic-Hotel.0-0-d1388-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Greenville](https://www.expedia.co.uk/Greenville-Hotels-Spa-Hotels.0-0-d1388-tSpaHotels.Travel-Guide-Filter-Hotels) - [Greenville Hotels](https://www.expedia.co.uk/Greenville-Hotels.d1388.Travel-Guide-Hotels) - [Mauldin Hotels](https://www.expedia.co.uk/Mauldin-Hotels.d183944.Travel-Guide-Hotels) - [Hotels near Patewood Memorial Hospital](https://www.expedia.co.uk/Patewood-Memorial-Hospital-Hotels.0-l6130783-0.Travel-Guide-Filter-Hotels) - [Pettigru Street Historic District Hotels](https://www.expedia.co.uk/Pettigru-Street-Historic-District-Greenville-Hotels.0-n6348167-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Simpsonville](https://www.expedia.co.uk/Simpsonville-Hotels-Gay-Friendly-Hotel.0-0-d6239-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Simpsonville](https://www.expedia.co.uk/Simpsonville-Hotels-Hotels-With-Indoor-Pools.0-0-d6239-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Simpsonville Hotels](https://www.expedia.co.uk/Simpsonville-Hotels.d6239.Travel-Guide-Hotels) - [West End Hotels](https://www.expedia.co.uk/West-End-Greenville-Hotels.0-n6348163-0.Travel-Guide-Filter-Hotels) - [Flights to Greenville](https://www.expedia.co.uk/Cheap-Flights-To-Greenville.d1388.Travel-Guide-Flights) - [Flights to Simpsonville](https://www.expedia.co.uk/Cheap-Flights-To-Simpsonville.d6239.Travel-Guide-Flights) - [Flights from Donaldson Center](https://www.expedia.co.uk/lp/airports/gdc/flights-from-donaldson-center-airport) - [Flights from Greenville Downtown](https://www.expedia.co.uk/lp/airports/gmu/flights-from-greenville-downtown-airport) - [Flights from Greenville](https://www.expedia.co.uk/lp/flights/1388/flights-from-greenville) - [Flights from Dunean](https://www.expedia.co.uk/lp/flights/553248634999354841/flights-from-dunean) - [Flights from Simpsonville](https://www.expedia.co.uk/lp/flights/6239/flights-from-simpsonville) - [Flights from Augusta (AGS) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/ags/gmu/augusta-to-greenville) - [Flights from Anderson (AND) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/and/gmu/anderson-to-greenville) - [Flights from Atlanta (ATL) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/atl/gmu/atlanta-to-greenville) - [Flights from Clemson (CEU) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/ceu/gdc/clemson-to-greenville) - [Flights from Washington (DCA) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/dca/gdc/washington-to-greenville) - [Flights from Detroit (DTW) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/dtw/gmu/detroit-to-greenville) - [Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/ewr/gmu/newark-liberty-intl-airport-to-greenville) - [Flights from Gaithersburg (GAI) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/gai/gmu/gaithersburg-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/grd/gmu/greenwood-to-greenville) - [Flights from Hagerstown (HGR) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/hgr/gmu/hagerstown-to-greenville) - [Flights from Hong Kong (HKG) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/hkg/gdc/hong-kong-to-greenville) - [Flights from Islip (ISP) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/isp/gmu/islip-to-greenville) - [Flights from Jacksonville (JAX) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/jax/gmu/jacksonville-to-greenville) - [Flights from Las Vegas (LAS) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/las/gmu/las-vegas-to-greenville) - [Flights from Los Angeles (LAX) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/lax/gmu/los-angeles-to-greenville) - [Flights from Pickens (LQK) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/lqk/gdc/pickens-to-greenville) - [Flights from Morgantown (MGW) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/mgw/gmu/morgantown-to-greenville) - [Flights from Dayton (MGY) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/mgy/gmu/dayton-to-greenville) - [Flights from Madison (MSN) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/msn/gdc/madison-to-greenville) - [Flights from New Orleans (MSY) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/msy/gmu/new-orleans-to-greenville) - [Flights from Paris (PAR) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/par/gdc/paris-to-greenville) - [Flights from Rocky Mount (RWI) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/rwi/gmu/rocky-mount-to-greenville) - [Flights from Louisville (SDF) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/sdf/gmu/louisville-to-greenville) - [Flights from St. Louis (STL) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/stl/gmu/st-louis-to-greenville) - [Flights from Taipei (TPE) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/tpe/gdc/taipei-to-greenville) - [Discovery Island Water Park](https://www.expedia.co.uk/Discovery-Island-Water-Park-Greenville.d553248621532656705.Attraction) - [Frankie's Fun Park](https://www.expedia.co.uk/Frankies-Fun-Park-Greenville.d553248621532656780.Attraction) - [Greenville Holidays](https://www.expedia.co.uk/Greenville.d1388.Holidays-City-Breaks) - [Visit Greenville](https://www.expedia.co.uk/Greenville.dx1388) - [Patewood Memorial Hospital](https://www.expedia.co.uk/Patewood-Memorial-Hospital-Greenville.d6130783.Attraction) - [Simpsonville Holidays](https://www.expedia.co.uk/Simpsonville.d6239.Holidays-City-Breaks) - [Warehouse Theatre](https://www.expedia.co.uk/Warehouse-Theatre-Greenville-Downtown.d553248621532656721.Attraction) - [Car hire Greenville](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Greenville.d1388.Car-Hire-Guide) - [Car hire Simpsonville](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Simpsonville.d6239.Car-Hire-Guide) - [Gantt Holiday Rentals](https://www.expedia.co.uk/Gantt-Holiday-Rentals.d553248634999376437.Travel-Guide-HolidayRentals) - [Greenville Holiday Rentals](https://www.expedia.co.uk/Greenville-Holiday-Rentals.d1388.Travel-Guide-HolidayRentals) - [Mauldin Holiday Rentals](https://www.expedia.co.uk/Mauldin-Holiday-Rentals.d183944.Travel-Guide-HolidayRentals) - [Things to do in Greenville](https://www.expedia.co.uk/Things-To-Do-In-Greenville.d1388.Travel-Guide-Activities) - [Things to do in Simpsonville](https://www.expedia.co.uk/Things-To-Do-In-Simpsonville.d6239.Travel-Guide-Activities) - [Book Spa Hotels in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-Spa-Hotel.0-0-d6057939-tSpaHotel.Travel-Guide-Filter-Hotels)