Title: TOP Dog-Friendly Hotels in Upstate South Carolina, SC for 2026 - Upstate South Carolina Pet-Friendly Hotels | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix # Find Dog-Friendly Hotels in Upstate South Carolina, SC - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Pet-Friendly Hotels Tonight [9 Jan - 10 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-09&endDate=2026-01-10&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-10&endDate=2026-01-11&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-09&endDate=2026-01-11&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina pet-friendly hotels ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/589bd84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/6abd26aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson [](https://www.expedia.co.uk/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) Seneca 9.0/10 Wonderful (1000) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gene £101 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/a7e2d124.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/1c93baf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/91f2c765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/a826354f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Simpsonville [](https://www.expedia.co.uk/Simpsonville-Hotels-Hampton-Inn-Simpsonville.h120431.Hotel-Information) Simpsonville 8.8/10 Excellent (596) "The hotel staff is excellent here. The rooms were very clean and very well furnished the bedding, and the bed itself was as comfortable as I remember in a while." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew £90 includes taxes & fees 23 Jan - 24 Jan [](https://www.expedia.co.uk/Simpsonville-Hotels-Hampton-Inn-Simpsonville.h120431.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/83fe6802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/7c7b67a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/94af1b49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/4c9b67dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gnome Hill Cottage - A Rustic Pet-Friendly Cottage In The Woods [](https://www.expedia.co.uk/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) Cleveland 9.8/10 Exceptional (109) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin £110 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) ![Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/b26b87ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 King Bed with Sofa bed, Courtyard View | Front of property](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/f825207a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Cabin, Courtyard View | Premium bedding, in-room safe, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/344b1497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Cabin, Courtyard View | Private kitchen | Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/5acfec99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carolina Camp Cedar [](https://www.expedia.co.uk/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) Pickens £143 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/5971f25f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/92684d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast ](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/9966f479.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. [](https://www.expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) Greenville 8.6/10 Excellent (94) "Great room, very clean and staff was friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £63 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/0f86ef1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/284160fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/6d084ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/e0e2877b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Anderson Downtown [](https://www.expedia.co.uk/Anderson-Hotels-Home2-Suites-By-Hilton-Anderson-Downtown.h65708685.Hotel-Information) Anderson 9.4/10 Exceptional (221) "Great hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) scott £116 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Anderson-Hotels-Home2-Suites-By-Hilton-Anderson-Downtown.h65708685.Hotel-Information) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/f6f7c8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/81c4f249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/eab53b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 [](https://www.expedia.co.uk/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) Seneca 8.0/10 Very good (667) "Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise £65 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/59f41330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/2b4321e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/7796ec2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/0a2d26b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson [](https://www.expedia.co.uk/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) Anderson 8.2/10 Very good (1000) "Room was clean, front desk people were very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caressa £62 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/5000000/4420000/4410900/4410857/0bc86a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4420000/4410900/4410857/6c57d886.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4420000/4410900/4410857/0f7a5a0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/5000000/4420000/4410900/4410857/f5c48dfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Union [](https://www.expedia.co.uk/Union-Hotels-Rodeway-Inn.h4410857.Hotel-Information) Union 8.2/10 Very good (203) "Room was nice and very clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eddie £43 includes taxes & fees 23 Jan - 24 Jan [](https://www.expedia.co.uk/Union-Hotels-Rodeway-Inn.h4410857.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/8238721d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Double Beds, Non Smoking | Living area | 37-inch flat-screen TV with cable channels, TV, pay films](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/f2d60448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Greenville Golf Resort & Conference Center [](https://www.expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) Greenville 9.0/10 Wonderful (1017) "Great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kurt £77 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-23&endDate=2026-01-24®ionId=6057939&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Everything was really great from start to finish. Check in was smooth because I did the preregistration on line." [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Staff was really nice " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "All were excellent " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Great service, good price, staff very friendly" [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ## Explore a world of travel with Expedia - 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