Title: TOP Dog-Friendly Hotels in Upstate South Carolina, SC for 2025 - Upstate South Carolina Pet-Friendly Hotels | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix # Find Dog-Friendly Hotels in Upstate South Carolina, SC - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Pet-Friendly Hotels Tonight [24 Nov - 25 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-11-24&endDate=2025-11-25&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [25 Nov - 26 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-11-25&endDate=2025-11-26&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-11-28&endDate=2025-11-30&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-12-05&endDate=2025-12-07&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Pet-Friendly Hotels ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible (Hearing, Roll-In Shower) | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/d36e662a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/2bb8d81a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Seneca Clemson Seneca 9.2/10 Wonderful (781) "Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gretchen £80 includes taxes & fees 12 Dec - 13 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Standard Cabin, Courtyard View | Premium bedding, in-room safe, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/7cda1ce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Cabin, Courtyard View | Premium bedding, in-room safe, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/344b1497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 King Bed with Sofa bed, Courtyard View | Private kitchen | Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/7f4f7187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/ddc562e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carolina Camp Cedar Pickens £152 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/fbbe5f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/c08a69bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/d45e119a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/56ecee45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Greer Greenville, SC Greer 9.6/10 Exceptional (406) "Nice hotel, convenient location with helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike £116 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Greer-Hotels-Hampton-Inn-Greer-Greenville.h68975422.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/88b33cc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, pool loungers](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/704d2b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/8e2d308e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/a74bbe34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Greenville Downtown Greenville Downtown 9.6/10 Exceptional (1007) "Great room, great staff, excellent breakfast, super clean. perfect location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arnold £75 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/d191b963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/01158bad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson Seneca 9.0/10 Wonderful (1006) "Overall great stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel £103 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking | Pillow-top beds, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/347fe1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/eab53b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/270-2efd6ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 Downtown 8.0/10 Very good (659) "Friendly check in, clean room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) connie £68 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/0304ce09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/573947b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking | Blackout curtains, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/c05bf676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Gaffney Gaffney 8.8/10 Excellent (664) "Clean room, great staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) gary £73 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/441edd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/7bc9a82a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/7cb8ae6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Anderson Anderson 7.8/10 Good (1017) "Rooms were clean, the property was well kept, complimentary breakfast and location is close to everything. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla £53 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/f93d0c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/706f626f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/94f8bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/452fcf9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson Anderson 8.2/10 Very good (1002) "Room was clean, staff was nice! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martina £68 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/0f86ef1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/341f715f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/284160fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/ee321bf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Anderson Downtown Anderson 9.4/10 Exceptional (211) "Room was available ahead of schedule and check in was made easy and great by the young lady at the front desk." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank £121 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Home2-Suites-By-Hilton-Anderson-Downtown.h65708685.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-08&endDate=2025-12-09®ionId=6057939&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_BF_PROMO_6057939) ## Top Upstate South Carolina Hotel Reviews ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Overall good!! " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Clean room, staff and amenities" [](https://expedia.co.uk/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Ac was great. Room was clean. Bed was very comfortable. Really enjoyed our stay. " [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Best Western Greenville Airport Inn](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f_y.jpg) ### Best Western Greenville Airport Inn 10/10 Excellent "Good all around the board" [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "The room was clean and the location was perfect to all of the downtown attractions " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Room was very nice...very clean and comfortable. Breakfast was very good...lots of selections. Definately recommend" [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Hotels with a View in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-A-View.0-0-d242-thotelwithaview.Hotel-Filter-Destinations) - [Hotels with Air Conditioning in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-Air-Conditioning.0-0-d242-thotelwithairconditioning.Hotel-Filter-Destinations) - [Hotels with Breakfast in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-Breakfast.0-0-d242-thotelwithbreakfast.Hotel-Filter-Destinations) - [Hotels with Connecting Rooms in South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina-Hotel-With-Connecting-Rooms.0-0-d242-thotelwithconnectingrooms.Hotel-Filter-Destinations) - 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