Title: TOP Marina Hotels in Upstate South Carolina, SC for 2025 | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![Greenville - Spartanburg which includes views, tranquil scenes and mountains](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Marina Hotels in Upstate South Carolina ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Marina Hotels Tonight [10 Sept - 11 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-09-10&endDate=2025-09-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Sept - 12 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-09-11&endDate=2025-09-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [12 Sept - 14 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-09-12&endDate=2025-09-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-09-19&endDate=2025-09-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Marina Hotels ## Our top choices for Upstate South Carolina marina hotels ![Dock](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/07befbdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/668722e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/18582505.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/ca7d3507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greystone Inn Lake Toxaway 9.4/10 Exceptional (82) "Most beautiful quiet and peaceful old guest home. " £272 includes taxes & fees 11 Sept - 12 Sept [](https://www.expedia.co.uk/Highlands-Hotels-Greystone-Inn.h23208596.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-09-24&endDate=2025-09-25®ionId=6057939&adults=2&property_amenities_group_explore=marina_on_site&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Choose Your Upstate South Carolina Hotel Style - [Business Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Business-Hotel.0-0-d6057939-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Budget-Hotels.0-0-d6057939-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Family-Friendly-Hotel.0-0-d6057939-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Golf Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Golf-Hotels.0-0-d6057939-tGolfHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Historic-Hotel.0-0-d6057939-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels Suites in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-Suites.0-0-d6057939-thotelsuites.Travel-Guide-Filter-Hotels) - [Hotels near Museums in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-Near-Museums.0-0-d6057939-thotelnearmuseums.Travel-Guide-Filter-Hotels) - [Hotels with Air Conditioning in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Air-Conditioning.0-0-d6057939-thotelwithairconditioning.Travel-Guide-Filter-Hotels) - [Hotels with Airport Transfers in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Airport-Transfers.0-0-d6057939-thotelwithairporttransfers.Travel-Guide-Filter-Hotels) - [Hotels with Breakfast in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Breakfast.0-0-d6057939-thotelwithbreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Connecting-Rooms.0-0-d6057939-thotelwithconnectingrooms.Travel-Guide-Filter-Hotels) - [Hotels with Entertainment in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Entertainment.0-0-d6057939-thotelwithentertainment.Travel-Guide-Filter-Hotels) - [Hotels with Gym in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Gym.0-0-d6057939-thotelwithgym.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotels-With-Hot-Tubs.0-0-d6057939-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Service in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Laundry-Service.0-0-d6057939-thotelwithlaundryservice.Travel-Guide-Filter-Hotels) - [Hotels with Parking in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Parking.0-0-d6057939-thotelwithparking.Travel-Guide-Filter-Hotels) - [Hotels with Parking in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Free-Parking.0-0-d6057939-thotelwithfreeparking.Travel-Guide-Filter-Hotels) - [Hotels with Pool in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotels-With-Pool.0-0-d6057939-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Hotels with Restaurant in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Restaurant.0-0-d6057939-thotelwithrestaurant.Travel-Guide-Filter-Hotels) - [Hotels with Room Service in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-Room-Service.0-0-d6057939-thotelwithroomservice.Travel-Guide-Filter-Hotels) - [Hotels with Wifi in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotels-With-WiFi.0-0-d6057939-tHotelswithWiFi.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-A-Bar.0-0-d6057939-thotelwithabar.Travel-Guide-Filter-Hotels) - [Hotels with a View in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotel-With-A-View.0-0-d6057939-thotelwithaview.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Hotels-With-Smoking-Rooms.0-0-d6057939-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Lakeside Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Lakeside-Hotel.0-0-d6057939-tlakesidehotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Luxury-Hotel.0-0-d6057939-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Pet-Friendly-Hotel.0-0-d6057939-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Romantic-Hotel.0-0-d6057939-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Shopping Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Shopping-Hotel.0-0-d6057939-tshoppinghotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Spa-Hotels.0-0-d6057939-tSpaHotels.Travel-Guide-Filter-Hotels) - [Sports Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Adventure-Sport-Hotel.0-0-d6057939-tAdventureSportHotel.Travel-Guide-Filter-Hotels) - [Wedding Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels-Wedding-Hotel.0-0-d6057939-tWeddingHotel.Travel-Guide-Filter-Hotels) ### More accommodation types in Upstate South Carolina - [Apartments in South Carolina](https://expedia.co.uk/South-Carolina-Apartments.d242-aaApartments.Travel-Guide-Accommodation) - [Cottages in South Carolina](https://expedia.co.uk/South-Carolina-Cottages.d242-aaCottages.Travel-Guide-Accommodation) - [Cabin Rentals in South Carolina](https://expedia.co.uk/South-Carolina-Cabins.d242-aaCabins.Travel-Guide-Accommodation) - [Serviced Apartments in South Carolina](https://expedia.co.uk/South-Carolina-Apart-Hotels.d242-aaApartHotels.Travel-Guide-Accommodation) - [B&B in South Carolina](https://expedia.co.uk/South-Carolina-Bed-And-Breakfasts.d242-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Farmstay in South Carolina](https://expedia.co.uk/South-Carolina-Agritourism.d242-aaAgritourism.Travel-Guide-Accommodation) - [Caravan Parks in South Carolina](https://expedia.co.uk/South-Carolina-Caravan-Parks.d242-aaCaravanParks.Travel-Guide-Accommodation) - [Lodges in South Carolina](https://expedia.co.uk/South-Carolina-Lodges.d242-aaLodges.Travel-Guide-Accommodation) - [Chalets in South Carolina](https://expedia.co.uk/South-Carolina-Chalets.d242-aaChalets.Travel-Guide-Accommodation) - [Inns in South Carolina](https://expedia.co.uk/South-Carolina-Inns.d242-aaInns.Travel-Guide-Accommodation) - [Town Houses in South Carolina](https://expedia.co.uk/South-Carolina-Town-Houses.d242-aaTownHouses.Travel-Guide-Accommodation) ### Hotels near popular Upstate South Carolina Attractions - [Hotels near Fred W. Symmes Chapel](https://expedia.co.uk/Fred-W-Symmes-Chapel-Hotels.0-l553248621532656718-0.Travel-Guide-Filter-Hotels) ### Hotels in Upstate South Carolina by Star Rating - [4 Star Hotels in Upstate South Carolina](https://expedia.co.uk/4Star-Upstate-South-Carolina-Hotels.s40-0-d6057939.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Upstate South Carolina](https://expedia.co.uk/3Star-Upstate-South-Carolina-Hotels.s30-0-d6057939.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Upstate South Carolina](https://expedia.co.uk/2Star-Upstate-South-Carolina-Hotels.s20-0-d6057939.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Best Western Plus Clemson Hotel & Conference Center](https://expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) - [Holiday Inn Greenville - Woodruff Road by IHG](https://expedia.co.uk/Greenville-Spartanburg-Hotels-Holiday-Inn-Woodruff-Road.h41964398.Hotel-Information) - [The Shepherd Hotel Downtown Clemson](https://expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) - [Woodspring Suites Greenville Airport](https://expedia.co.uk/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) - [Embassy Suites by Hilton Greenville Downtown Riverplace](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) - [Drury Inn & Suites Greenville](https://expedia.co.uk/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) - [Inn @ Clemson](https://expedia.co.uk/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) - [ECHO Suites Extended Stay by Wyndham Spartanburg](https://expedia.co.uk/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) - [Lakeside Lodge Clemson](https://expedia.co.uk/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) - [Comfort Inn & Suites Greer - Greenville](https://expedia.co.uk/Greer-Hotels-Comfort-Inn-Suites-Greer-Greenville.h67445.Hotel-Information) - [Best Western Travelers Rest Greenville](https://expedia.co.uk/Travelers-Rest-Hotels-Best-Western-Travelers-Rest-Greenville.h105540.Hotel-Information) - [Clemson University's James F. Martin Inn](https://expedia.co.uk/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) [See a list of all hotels in Upstate South Carolina](https://expedia.co.uk/All-Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - [Hotels in Anna Maria Island](https://expedia.co.uk/Anna-Maria-Island-Hotels.d553248622847118534.Travel-Guide-Hotels) - [Hotels in Maui](https://expedia.co.uk/Maui-Hotels.d180073.Travel-Guide-Hotels) - [Hotels in Cape Cod](https://expedia.co.uk/Cape-Cod-Hotels.d180061.Travel-Guide-Hotels) - [Charleston Historic District Hotels](https://expedia.co.uk/Charleston-Historic-District-Charleston-Hotels.0-n6057948-0.Travel-Guide-Filter-Hotels) - [Hotels in Martha's Vineyard](https://expedia.co.uk/Marthas-Vineyard-Hotels.d6047691.Travel-Guide-Hotels) - [Hotels in Hamptons](https://expedia.co.uk/Hamptons-Hotels.d6056452.Travel-Guide-Hotels) Flights - [Cheap Flights to Norfolk - Virginia Beach](https://expedia.co.uk/Cheap-Flights-To-Norfolk-Virginia-Beach.d602904.Travel-Guide-Flights) - [Cheap Flights to Fort Walton Beach - Destin](https://expedia.co.uk/Cheap-Flights-To-Fort-Walton-Beach-Destin.d6023392.Travel-Guide-Flights) - [Cheap Flights to Kauai](https://expedia.co.uk/Cheap-Flights-To-Kauai.d180075.Travel-Guide-Flights) - [Cheap Flights to Greenville - Spartanburg](https://expedia.co.uk/Cheap-Flights-To-Greenville-Spartanburg.d6035267.Travel-Guide-Flights) - [Cheap Flights to Maui](https://expedia.co.uk/Cheap-Flights-To-Maui.d180073.Travel-Guide-Flights) - [Cheap Flights to Martha's Vineyard](https://expedia.co.uk/Cheap-Flights-To-Marthas-Vineyard.d6047691.Travel-Guide-Flights) - [Cheap Flights to Outer Banks](https://expedia.co.uk/Cheap-Flights-To-Outer-Banks.d602135.Travel-Guide-Flights) - [Cheap Flights to Nantucket Island](https://expedia.co.uk/Cheap-Flights-To-Nantucket-Island.d6047676.Travel-Guide-Flights) - [Cheap Flights to Cape Cod](https://expedia.co.uk/Cheap-Flights-To-Cape-Cod.d180061.Travel-Guide-Flights) - [Cheap Flights to Hawaii Island](https://expedia.co.uk/Cheap-Flights-To-Hawaii-Island.d180074.Travel-Guide-Flights) - [Cheap Flights to Long Island](https://expedia.co.uk/Cheap-Flights-To-Long-Island.d602887.Travel-Guide-Flights) Cars - [Car hire in Maui](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Maui.d180073.Car-Hire-Guide) - [Car hire in Kauai](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Kauai.d180075.Car-Hire-Guide) - [Car hire in Charleston](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Charleston-Intl.d5457987.Car-Hire-Guide) Activities - [Things to do in South Florida](https://expedia.co.uk/Things-To-Do-In-South-Florida.d6233792.Travel-Guide-Activities) Packages - [Aspen Snowmass Holidays](https://expedia.co.uk/Aspen-Snowmass.d553248621593965848.Holidays-City-Breaks) - [Family Kingdom Amusement Park](https://expedia.co.uk/Family-Kingdom-Amusement-Park-Myrtle-Beach.d6079999.Attraction) - [Martha's Vineyard Holidays](https://expedia.co.uk/Marthas-Vineyard.d6047691.Holidays-City-Breaks) - [Outer Banks Holidays](https://expedia.co.uk/Outer-Banks.d602135.Holidays-City-Breaks) - [Anna Maria Island Holidays](https://expedia.co.uk/Anna-Maria-Island.d553248622847118534.Holidays-City-Breaks) - [Cape Cod Holidays](https://expedia.co.uk/Cape-Cod.d180061.Holidays-City-Breaks) - [Maui Holidays](https://expedia.co.uk/Maui.d180073.Holidays-City-Breaks) - [Hamptons Holidays](https://expedia.co.uk/Hamptons.d6056452.Holidays-City-Breaks) - [Niagara Falls - Western New York Holidays](https://expedia.co.uk/Niagara-Falls-Western-New-York.d6056506.Holidays-City-Breaks) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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