Photo by RVLuckyorWhat
Search Business Hotels in Upstate South Carolina
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Upstate South Carolina Business Hotels
Our top choices for Upstate South Carolina business-friendly hotels
1. Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,550 reviews)
"Good breakfast nice room friendly staff"
Sidney
The price is £86
includes taxes & fees
9 Aug - 10 Aug
2. Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,325 reviews)
"Love staying here on my stops to Atlanta."
Angela
The price is £89
includes taxes & fees
17 Aug - 18 Aug
9.6 out of 10, Exceptional, (1,064 reviews)
"Great place to stay for families -- food is also very good."
Aaron
The price is £94
includes taxes & fees
10 Aug - 11 Aug
4. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
8.6 out of 10, Excellent, (323 reviews)
"Clean room, helpful staff, okay breakfast, and close to everything in town"
Kelley
The price is £68
includes taxes & fees
2 Sept - 3 Sept
8.8 out of 10, Excellent, (1,000 reviews)
"Great stay!!!"
Robert
The price is £82
includes taxes & fees
15 Aug - 16 Aug
9.2 out of 10, Wonderful, (380 reviews)
"Comfortable rooms with nice bedding. Had a large group staying for a wedding. Everyone happy with accomodations. Would highly recommend."
sarah
The price is £89
includes taxes & fees
9 Aug - 10 Aug
8.6 out of 10, Excellent, (1,005 reviews)
"We usually visit SC a couple of times a year and we stay here. The rooms are spacious, the breakfast is good, grandkids enjoy the pool, and staff members are always polite & helpful."
Michelle
The price is £86
includes taxes & fees
28 Aug - 29 Aug
8. SpringHill Suites by Marriott Greenville Downtown
SpringHill Suites by Marriott Greenville DowntownGreenville Downtown
9.6 out of 10, Exceptional, (1,008 reviews)
"Very clean hotel and was within walking distance to everything!"
Don
The price is £104
includes taxes & fees
16 Aug - 17 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Upstate South Carolina Hotel Reviews
Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- 3 Star Hotels in Greenville - Spartanburg
- 5 Star Hotels in Greenville
- Gay-Friendly Hotels in Anderson
- Gay-Friendly Hotels in Clinton
- Hotels near Frankie's Fun Park
- Caravan Parks in Greenville
- 1br Near DT & Mountain Goat Cafe
- 5br Group Getaway
- Baymont by Wyndham Greenville Woodruff Rd
- Best Western Plus Greenville I
- Boutique Hotels in Greenville
- Crowne Plaza Hotel Greenville
- Doubletree by Hilton Greenville Woodruff Road
- Downtown Penthouse With Terrace
- Budget Inn Greenville By Hotel O I
- Ellison on Broad
- Grand Bohemian Lodge Greenville
- Hampton Inn Greenville/I
- Hampton Inn & Suites Greenville
- Home2 Suites by Hilton Greenville Airport
- Homewood Suites by Hilton Greenville
- Hyatt Place Greenville Downtown
- Hyatt Place Greenville/Haywood
- Luxury 4BR Home with Screened Porch & Fenced Yard
- Luxury Hotels in Greenville
- Modern Comfort in Gated 2BR Apartment with Parking
- Modern Urban Retreat in Downtown Greenville
- Luxury Loft Sleeps 6 on Main Street
- Walk to Paris Mtn State Park Sleeps 14 King Beds Fire Pit
- Studio 6 Greenville
- Swamp Rabbit Inn
- Secluded Tiny Home in Exclusive Paris Mountain!
- Trio Loft
- Urban Boutique Hotel
- Wingate by Wyndham
- Greenville Hotels
- Cheap Hotels in Greenville - Spartanburg
- Historic Hotels in Greenville - Spartanburg
- Hotels with Balcony in Greenville - Spartanburg
- Hotels with Indoor Pools in Greenville - Spartanburg
- Mint House Greenville Downtown by Kasa
- Mountain Hotels in Greenville - Spartanburg
- Romantic Hotels in Greenville - Spartanburg
- Tru by Hilton Greenville Woodruff Road
- Gay-Friendly Hotels in Greer
- Playroom & Home Office
- Fairfield By Marriott Inn & Suites Piedmont Greenville
- The Golden Grove Getaway / 15 min to downtown Greenville
- Gay-Friendly Hotels in Simpsonville
- Hotels with Indoor Pools in Simpsonville
- Boutique Hotels in Upstate South Carolina
- Mountain Hotels in Upstate South Carolina
- Woodside Cotton Mill Village Historic District Hotels
- Flights to Greenville - Spartanburg
- Flights to Greenville
- Flights to Piedmont
- Flights to Simpsonville
- Flights to Upstate South Carolina
- Flights from Donaldson Center
- Flights from Greenville-Spartanburg Intl.
- Virgin Atlantic Manchester (MAN) to Greenville (GSP) flights
- Flights from Greenville
- Flights from Simpsonville
- Flights from Augusta (AGS) to Greenville (GMU)
- Flights from Atlanta (ATL) to Greenville (GMU)
- Flights from Atlanta (ATL) to Greenville (GSP)
- Flights from Birmingham (BHX) to Greenville (GSP)
- Flights from Nashville (BNA) to Greenville (GSP)
- Flights from Baltimore (BWI) to Greenville (GSP)
- Flights from Charleston (CHS) to Greenville (GSP)
- Flights from Charlotte (CLT) to Greenville (GSP)
- Flights from Washington (DCA) to Greenville (GSP)
- Flights from Dublin (DUB) to Greenville (GSP)
- Flights from Edinburgh (EDI) to Greenville (GSP)
- Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
- Flights from Gaithersburg (GAI) to Greenville (GMU)
- Flights from Glasgow (GLA) to Greenville (GSP)
- Flights from New York (JFK) to Greenville (GSP)
- Flights from Los Angeles (LAX) to Greenville (GMU)
- Flights from Leeds (LBA) to Greenville (GSP)
- Flights from London (LGW) to Greenville (GSP)
- Flights from London (LHR) to Greenville (GSP)
- Flights from London (LON) to Greenville (GSP)
- Flights from Manchester (MAN) to Greenville (GSP)
- Flights from Orlando (MCO) to Greenville (GSP)
- Flights from Miami (MIA) to Greenville (GSP)
- Flights from Newcastle (NCL) to Greenville (GSP)
- Flights from Chicago (ORD) to Greenville (GSP)
- Flights from Rota (ROP) to Greenville (GSP)
- Flights from Tampa (TPA) to Greenville (GSP)