Photo by RVLuckyorWhat
Search Business Hotels in Upstate South Carolina
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Upstate South Carolina Business Hotels
Our top choices for Upstate South Carolina business-friendly hotels
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (247 reviews)
"Staff was pleasant."
BRIAN
The price is £102
includes taxes & fees
20 Jul - 21 Jul
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (635 reviews)
"Awesome service and courteous staff the whole stay!!!"
Edna
The price is £80
includes taxes & fees
9 Aug - 10 Aug
9.2 out of 10, Wonderful, (864 reviews)
"Room was clean staff was great breakfast was good"
Jason
The price is £87
includes taxes & fees
21 Jul - 22 Jul
Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,534 reviews)
"Location was very convenient and the breakfast was nice."
Shabana
The price is £78
includes taxes & fees
9 Aug - 10 Aug
8.6 out of 10, Excellent, (1,004 reviews)
"Very nice stay"
Stephanie
The price is £74
includes taxes & fees
26 Jul - 27 Jul
9.2 out of 10, Wonderful, (1,000 reviews)
"Excellent location. Good food and drinks at the bar. Awesome room."
Johari
The price is £100
includes taxes & fees
2 Aug - 3 Aug
5.6 out of 10, (355 reviews)
"Convenient and close to everything rooms are nice and staff is friendly "
Daniel
The price is £70
includes taxes & fees
21 Jul - 22 Jul
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHGSpartanburg
8.6 out of 10, Excellent, (965 reviews)
"Clean and breakfast was good"
Thomas
The price is £63
includes taxes & fees
2 Aug - 3 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Upstate South Carolina Hotel Reviews
Comfort Inn Greenville - Haywood Mall
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- 3 Star Hotels in Greenville - Spartanburg
- 5 Star Hotels in Greenville
- Gay-Friendly Hotels in Anderson
- Gay-Friendly Hotels in Clinton
- Hotels near Frankie's Fun Park
- Caravan Parks in Greenville
- 1br Near DT & Mountain Goat Cafe
- 5br Group Getaway
- Baymont by Wyndham Greenville Woodruff Rd
- Best Western Plus Greenville I
- Boutique Hotels in Greenville
- Crowne Plaza Hotel Greenville
- Doubletree by Hilton Greenville Woodruff Road
- Downtown Penthouse With Terrace
- Budget Inn Greenville By Hotel O I
- Ellison on Broad
- Grand Bohemian Lodge Greenville
- Hampton Inn Greenville/I
- Hampton Inn & Suites Greenville
- Home2 Suites by Hilton Greenville Airport
- Homewood Suites by Hilton Greenville
- Hyatt Place Greenville Downtown
- Hyatt Place Greenville/Haywood
- Luxury 4BR Home with Screened Porch & Fenced Yard
- Luxury Hotels in Greenville
- Modern Comfort in Gated 2BR Apartment with Parking
- Modern Urban Retreat in Downtown Greenville
- Luxury Loft Sleeps 6 on Main Street
- Walk to Paris Mtn State Park Sleeps 14 King Beds Fire Pit
- Studio 6 Greenville
- Swamp Rabbit Inn
- Secluded Tiny Home in Exclusive Paris Mountain!
- Trio Loft
- Urban Boutique Hotel
- Wingate by Wyndham
- Greenville Hotels
- Cheap Hotels in Greenville - Spartanburg
- Historic Hotels in Greenville - Spartanburg
- Hotels with Balcony in Greenville - Spartanburg
- Hotels with Indoor Pools in Greenville - Spartanburg
- Mint House Greenville Downtown by Kasa
- Mountain Hotels in Greenville - Spartanburg
- Romantic Hotels in Greenville - Spartanburg
- Tru by Hilton Greenville Woodruff Road
- Gay-Friendly Hotels in Greer
- Playroom & Home Office
- Fairfield By Marriott Inn & Suites Piedmont Greenville
- The Golden Grove Getaway / 15 min to downtown Greenville
- Gay-Friendly Hotels in Simpsonville
- Hotels with Indoor Pools in Simpsonville
- Boutique Hotels in Upstate South Carolina
- Mountain Hotels in Upstate South Carolina
- Woodside Cotton Mill Village Historic District Hotels
- Flights to Greenville - Spartanburg
- Flights to Greenville
- Flights to Piedmont
- Flights to Simpsonville
- Flights to Upstate South Carolina
- Flights from Donaldson Center
- Flights from Greenville-Spartanburg Intl.
- Virgin Atlantic Manchester (MAN) to Greenville (GSP) flights
- Flights from Greenville
- Flights from Simpsonville
- Flights from Augusta (AGS) to Greenville (GMU)
- Flights from Atlanta (ATL) to Greenville (GMU)
- Flights from Atlanta (ATL) to Greenville (GSP)
- Flights from Birmingham (BHX) to Greenville (GSP)
- Flights from Nashville (BNA) to Greenville (GSP)
- Flights from Baltimore (BWI) to Greenville (GSP)
- Flights from Charleston (CHS) to Greenville (GSP)
- Flights from Charlotte (CLT) to Greenville (GSP)
- Flights from Washington (DCA) to Greenville (GSP)
- Flights from Dublin (DUB) to Greenville (GSP)
- Flights from Edinburgh (EDI) to Greenville (GSP)
- Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
- Flights from Gaithersburg (GAI) to Greenville (GMU)
- Flights from Glasgow (GLA) to Greenville (GSP)
- Flights from New York (JFK) to Greenville (GSP)
- Flights from Los Angeles (LAX) to Greenville (GMU)
- Flights from Leeds (LBA) to Greenville (GSP)
- Flights from London (LGW) to Greenville (GSP)
- Flights from London (LHR) to Greenville (GSP)
- Flights from London (LON) to Greenville (GSP)
- Flights from Manchester (MAN) to Greenville (GSP)
- Flights from Orlando (MCO) to Greenville (GSP)
- Flights from Miami (MIA) to Greenville (GSP)
- Flights from Newcastle (NCL) to Greenville (GSP)
- Flights from Chicago (ORD) to Greenville (GSP)
- Flights from Rota (ROP) to Greenville (GSP)
- Flights from Tampa (TPA) to Greenville (GSP)