A coastal cityscape with a prominent Ferris wheel, beachfront, and high-rise buildings.

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South Carolina Accommodation: Most Popular Cities to Stay

A riverside walkway with cyclists, a bridge, and modern buildings.
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Greenville

Greenville

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Our top choices for South Carolina business-friendly hotels

A covered outdoor area with a stone facade, a bench, and a truck parked nearby.

1. Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall
2.5 star property
Greenville
8.2 out of 10, Very good, (1,006 reviews)
"Thought breakfast was good staff helpful when I goofed up stay request and they added the extra day Room clean and organized"
United States
Susan
The price is £69
includes taxes & fees
4 Oct - 5 Oct
Comfort Inn Greenville - Haywood Mall
A modern hotel with a glass facade, a covered entrance, and a clear sky.

2. Hyatt Place Charleston Airport/Convention Center

Hyatt Place Charleston Airport/Convention Center
3.0 star property
North Charleston
9.4 out of 10, Exceptional, (1,256 reviews)
"Great place to stay"
United States
Gabriel
The price is £97
includes taxes & fees
28 Sept - 29 Sept
Hyatt Place Charleston Airport/Convention Center
A rooftop bar with tables and chairs, overlooking a cityscape at dusk.

3. Sheraton Columbia Downtown Hotel

Sheraton Columbia Downtown Hotel
3.5 star property
Downtown Columbia
8.4 out of 10, Very good, (1,003 reviews)
"Friendly staff"
United States
Ericka
The price is £95
includes taxes & fees
27 Sept - 28 Sept
Sheraton Columbia Downtown Hotel
A hotel with a curved facade, large windows, and a central tower.

4. Town & Country Inn and Suites

Town & Country Inn and Suites
3.0 star property
West Ashley
9.2 out of 10, Wonderful, (1,162 reviews)
"Great location and the room was very comfortable and clean. We will certainly choose this property again!"
United States
Barbara
The price is £118
includes taxes & fees
24 Sept - 25 Sept
Town & Country Inn and Suites
A spacious living area with a staircase, a sofa, a coffee table, and a desk with a chair.

5. Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente
2.5 star property
Greenville
8.0 out of 10, Very good, (1,000 reviews)
"The staff was very helpful and friendly. They were able to answer all of my questions since this was my first time staying there. The breakfast was great! Way more options than I was actually expecting and everything was cooked perfectly."
United States
Chris
The price is £59
includes taxes & fees
18 Oct - 19 Oct
Sleep Inn at Greenville Convention Cente
A hotel with a prominent tower, a covered entrance, and a well-lit facade.

6. La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
3.0 star property
Greenville
7.4 out of 10, Good, (1,146 reviews)
"Great place to stay for the pricing."
United States
James
The price is £56
includes taxes & fees
4 Oct - 5 Oct
La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
An outdoor patio with seating, a fire pit, string lights, and a grill area.

7. Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1,002 reviews)
"Great staff, great location, great rooms!"
United States
Sylvia
The price is £114
includes taxes & fees
11 Oct - 12 Oct
Home2 Suites by Hilton Greenville Downtown
A modern lobby with a seating area, a large abstract painting, and a staircase.

8. Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood
3.0 star property
Greenville
8.0 out of 10, Very good, (1,008 reviews)
"Great hotel"
United States
Jonathan
The price is £68
includes taxes & fees
18 Oct - 19 Oct
Hyatt Place Greenville/Haywood
A resort with a large pool, palm trees, and a view of the ocean.

9. Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island
4.0 star property
South End
8.8 out of 10, Excellent, (1,517 reviews)
"Very nice resort."
United States
Christy
The price is £232
includes taxes & fees
20 Oct - 21 Oct
Sonesta Resort Hilton Head Island
A hotel room with two beds, a desk with a computer, a chair, and a view of the outdoors.

10. Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest
2.5 star property
Seven Oaks
5.8 out of 10, (1,007 reviews)
"So dirty place, never come back"
United States
Asmaa
The price is £48
includes taxes & fees
24 Sept - 25 Sept
Baymont by Wyndham Columbia Northwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Hotel Reviews

Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

8/10 Good
"Beautiful property, really enjoyed the 2 pools that were located on the property."
Ray 5-night trip
Posted less than an hour ago
Harborside at Charleston Harbor Resort and Marina

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Frequently asked questions

How much do business hotels in South Carolina cost?
Prices for business hotels in South Carolina range between £48 and £232 per night. No matter your budget, Expedia can help you find the right place to get your work done. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business hotels in South Carolina?
South Carolina offers multiple business hotels with a total average guest review rating of 8.6. Have a work event in Charleston? Wentworth Mansion is a 5-star stay that's highly recommended by corporate travellers and features al fresco dining and a free cooked-to-order breakfast. Another in-demand choice for a business trip is French Quarter Inn. Also in Charleston, it has a 4-star rating and conveniences such as premium bedding and a garden.
How many business hotels are there in South Carolina?
When your next conference or event takes you someplace in South Carolina, you'll have 824 business hotels to pick from.
Are there any family-friendly hotels in South Carolina that are also business friendly?
Absolutely. You'll find some fantastic family-friendly hotels that are also business friendly in South Carolina. If you're on your way to Charleston, make a booking at Wentworth Mansion. It includes useful amenities like complimentary breakfast and childcare services and has a 5-star rating. Alternatively, consider French Quarter Inn. This 4-star stay in Charleston is ideal for both leisure and business travellers and offers complimentary breakfast, laundry facilities and lots more. There are loads of terrific things to do with your family in Charleston. Patriots Point and South Carolina Aquarium deliver a wonderful day out.
Are there any 5-star business hotels in South Carolina?
Select a hotel in South Carolina that's both business friendly and luxurious with Expedia. The top city of Charleston has some excellent options, such as Wentworth Mansion. A terrace and treatment rooms are two of the amenities at this 5-star retreat. Also check out The Charleston Place. Beauty services and concierge services help make this 5-star property in Charleston popular with corporate and leisure travellers alike.
Why book your business hotel in South Carolina with Expedia?
At Expedia, it's our job to help you locate an excellent stay at the right price. From fancy, corporate-friendly escapes to affordable hotels filled with all the amenities you need, you'll have your next work trip organised in a few simple clicks.
How can I find cheap business hotels in South Carolina?
When work takes you on the road in South Carolina, our "business friendly" filter will help you find a suitable hotel. From fast WiFi to meeting rooms and workspaces, they come with the amenities you need for a comfortable and productive stay. Another tip? Narrow your search by your budget and preferred star rating to see the cheapest options.
What is there to do in South Carolina near my business hotel?
Whether you like food, shopping, history or sightseeing, South Carolina is one place where it's difficult to be bored! The well-known city of Charleston has lots of attractions, including South Carolina Aquarium, Charleston Museum and Gibbes Museum of Art. If work is taking you to Myrtle Beach, Broadway at the Beach, SkyWheel Myrtle Beach and Family Kingdom Amusement Park are must-do's.