Find luxury hotels in Southeast Missouri, MO

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Check availability on Southeast Missouri Luxury Hotels

Our top choices for Southeast Missouri luxury hotels

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (598 reviews)
The price is £102
includes taxes & fees
16 Jun - 17 Jun
The Riverview

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,625 reviews)
The price is £93
includes taxes & fees
29 Jun - 30 Jun
River City Casino & Hotel

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,006 reviews)
  • cleanliness
    Upscale St. Louis retreat features pool, concierge, fine dining in prime business district.
The price is £117
includes taxes & fees
21 Jun - 22 Jun
Hilton St. Louis Frontenac

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,023 reviews)
The price is £120
includes taxes & fees
21 Jun - 22 Jun
Drury Plaza Hotel St. Louis Brentwood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Southeast Missouri

Southeast Missouriand its attractions for luxury travelers

Southeast Missouri boasts a compelling blend of natural beauty and cultural richness, perfect for the discerning traveller seeking luxury. Begin your journey in Cape Girardeau, where the historic Riverfront adds charm to your stay; indulge in a gourmet meal at a riverside restaurant followed by a leisurely stroll along the Mississippi River. For a touch of adventure, head to the stunning trails of the Ozark National Scenic Riverways, where you can explore crystal-clear springs and enjoy a private guided canoe tour, immersing yourself in Missouri's breathtaking landscapes. The historic town of Ste. Genevieve, rich in French historic architecture, offers boutique shopping and exquisite dining experiences that cater to refined tastes. The region’s acclaimed wineries, such as the nearby Chaumette Vineyards, provide exclusive tastings and vineyard tours, perfect for an afternoon of indulgence. For a luxurious stay, consider the upscale options in Cape Girardeau, where hotels offer stunning views of the river along with top amenities and personalised services, ensuring that you feel pampered throughout your visit.

Top Southeast Missouri Hotel Reviews

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