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Find Family-Friendly Hotels in Southeast Missouri, MO

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Check availability on Southeast Missouri Family-Friendly Hotels

Tonight
4 Sept - 5 Sept
Tomorrow
5 Sept - 6 Sept
This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

Our top choices for Southeast Missouri family-friendly hotels

1. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
  • Year-round family fun with inviting pools and free activities makes this Poplar Bluff inn perfect for kids of all ages.
£79
includes taxes & fees
12 Sept - 13 Sept
Drury Inn & Suites Poplar Bluff

2. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
£77
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Perryville by IHG

3. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
  • Seasonal outdoor pool and family-friendly perks create magical memories at this Farmington retreat just minutes from adventure.
£46
includes taxes & fees
13 Sept - 14 Sept
Baymont Inn and Suites by Wyndham Farmington, MO

4. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
  • A family paradise with splash-worthy fun awaits, where complimentary breakfast and an indoor pool create lasting memories for all ages.
£83
includes taxes & fees
27 Sept - 28 Sept
Drury Plaza Hotel Cape Girardeau Conference Center

5. Black River Motel and Restaurant

Black River Motel and Restaurant
Lesterville
£91
includes taxes & fees
15 Sept - 16 Sept
Black River Motel and Restaurant

6. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
£48
includes taxes & fees
13 Sept - 14 Sept
Super 8 by Wyndham Farmington

7. Quality Inn Farmington

Quality Inn Farmington
Farmington
  • Adventure awaits with a family-friendly indoor pool and free extras just minutes from St. Joe State Park.
£51
includes taxes & fees
15 Sept - 16 Sept
Quality Inn Farmington

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
£84
includes taxes & fees
20 Sept - 21 Sept
Fairfield Inn & Suites by Marriott Cape Girardeau

9. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
  • Family-friendly adventures await with free breakfast, cots, and easy access to Cape Splash Aquatic Centre, just minutes away.
£60
includes taxes & fees
27 Sept - 28 Sept
Pear Tree Inn Cape Girardeau West

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
  • Family getaway with indoor pool and kid-friendly perks near Cape Splash Family Aquatic Centre.
£74
includes taxes & fees
6 Sept - 7 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
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Choose what matters most at family-friendly hotels in Southeast Missouri

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Family-friendly hotels with free breakfast in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
£46
includes taxes & fees
13 Sept - 14 Sept
Baymont Inn and Suites by Wyndham Farmington, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
£80
includes taxes & fees
14 Sept - 15 Sept
Drury Inn & Suites Sikeston, MO

Quality Inn Farmington

Quality Inn Farmington
Farmington
£51
includes taxes & fees
15 Sept - 16 Sept
Quality Inn Farmington

Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
Farmington
£89
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express & Suites Farmington by IHG

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
£83
includes taxes & fees
27 Sept - 28 Sept
Drury Plaza Hotel Cape Girardeau Conference Center

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
£48
includes taxes & fees
13 Sept - 14 Sept
Super 8 by Wyndham Farmington

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
£84
includes taxes & fees
20 Sept - 21 Sept
Fairfield Inn & Suites by Marriott Cape Girardeau

Hampton Inn Farmington

Hampton Inn Farmington
Farmington
£85
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn Farmington

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
£74
includes taxes & fees
6 Sept - 7 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
£60
includes taxes & fees
27 Sept - 28 Sept
Pear Tree Inn Cape Girardeau West
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Family-friendly hotels with pools in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
£46
includes taxes & fees
13 Sept - 14 Sept
Baymont Inn and Suites by Wyndham Farmington, MO

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
£79
includes taxes & fees
12 Sept - 13 Sept
Drury Inn & Suites Poplar Bluff

Quality Inn Farmington

Quality Inn Farmington
Farmington
£51
includes taxes & fees
15 Sept - 16 Sept
Quality Inn Farmington

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
£83
includes taxes & fees
27 Sept - 28 Sept
Drury Plaza Hotel Cape Girardeau Conference Center

Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
Farmington
£89
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express & Suites Farmington by IHG

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
£48
includes taxes & fees
13 Sept - 14 Sept
Super 8 by Wyndham Farmington

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
£84
includes taxes & fees
20 Sept - 21 Sept
Fairfield Inn & Suites by Marriott Cape Girardeau

Hampton Inn Farmington

Hampton Inn Farmington
Farmington
£85
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn Farmington

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
£74
includes taxes & fees
6 Sept - 7 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pickleball Cafe & Micro Hotel

Pickleball Cafe & Micro Hotel
Ironton
£171
includes taxes & fees
7 Sept - 8 Sept
Pickleball Cafe & Micro Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find out more about Southeast Missouri

Family friendly things to do in Southeast Missouri

Southeast Missouri is a paradise of family-friendly adventures, perfect for those seeking both excitement and quality accommodation. Begin your journey at the stunning Lake of the Ozarks, where you can enjoy a wealth of water activities, from jet skiing to serene boat rides, all while soaking up the sun on sandy beaches. For a taste of nature, the stunning Elephant Rocks State Park invites families to hike among gigantic boulders that seem to defy gravity, providing a unique playground for kids and adults alike. A visit to the Discovery Playhouse in Cape Girardeau offers an interactive experience designed to spark curiosity and creativity in younger travellers, featuring hands-on exhibits that make learning fun. If your family is keen on history, the Missouri Civil War Museum in Cape Girardeau provides an engaging way to explore the region's rich past, with exhibits that captivate all ages. After a day of exploration, consider staying in the charming town of Cape Girardeau, where family-friendly hotels offer convenient access to these attractions and more. Many hotels here pride themselves on attentive service, providing amenities like spacious rooms and complimentary breakfasts, ensuring your family feels pampered during your stay. With easy access to both the natural beauty and cultural heritage of Southeast Missouri, you’ll create lasting memories while enjoying the comforts and quality service that meet your family's high expectations.

Top Southeast Missouri Hotel Reviews

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Clean room friendly staff"
Michelle 1-night trip
Posted 5 hours ago
Pear Tree Inn Cape Girardeau West
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

10/10 Excellent
"We were greeted with a warm smile from a really nice gentleman that checked us in. He chatted with us the entire time we checked in. He gave us ideas where to eat and Lamberts won. The hotel and room was very clean. Breakfast was great. They serve something hot everyday like biscuits and gravy, eggs, sausage and some days bacon. Highly recommend this hotel."
Mary 1-night trip
Posted 8 hours ago
Best Western Plus Sikeston I-55
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Very nice and clean property."
Julie 2-night trip
Posted 13 hours ago
Drury Inn & Suites Sikeston, MO
Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

8/10 Good
"room was clean and the front staff was nice. place served it's purpose (stayed for only 2 nights). Not much amenitites."
johnny 2-night trip
Posted 1 day ago
Comfort Inn Festus - St Louis South
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"This location is a must stay any time I am traveling in the area. The staff are helpful. There are lots of dinning options near by. I can always count on a peaceful night sleep at this location."
Jesse 1-night trip
Posted 1 day ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

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