Title: TOP Family-Friendly Hotels in Southeast Missouri, MO for 2025 - Southeast Missouri Family Welcoming Hotels | Expedia.co.uk [Southeast Missouri Travel Guide](https://expedia.co.uk/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.co.uk/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Holiday Rentals in Southeast Missouri](https://expedia.co.uk/Southeast-Missouri-Holiday-Rentals.d6058763.Travel-Guide-HolidayRentals)[Flights to Southeast Missouri](https://expedia.co.uk/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Missouri.d6058763.Car-Hire-Guide)[Southeast Missouri Holidays](https://expedia.co.uk/Southeast-Missouri.d6058763.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/9/6538ce9b088c58039b33a5fe701e7a1f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Family-Friendly Hotels in Southeast Missouri, MO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Missouri Family-Friendly Hotels Tonight [9 Oct - 10 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-10-09&endDate=2025-10-10&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-10-10&endDate=2025-10-11&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058763&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Missouri Family-Friendly Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast ](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8df39481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston Sikeston 9.4/10 Exceptional (1009) "Wonderful place to stay" £66 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub) | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO Sikeston 9.4/10 Exceptional (1002) "Very nice and quiet " £77 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/a3a28e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Refrigerator & Microwave (Sofabed, 2 Rooms, Tub) | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/83931306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b2d719b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Poplar Bluff Poplar Bluff 9.2/10 Wonderful (919) "Dining options were excellent " £79 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1013) "Great place" £76 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1005) "Room was clean, it is an affordable option to stay for a day or two " £59 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/d18ea228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn By Hilton Dexter Dexter £95 includes taxes & fees 8 Nov - 9 Nov [](https://www.expedia.co.uk/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking | 1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/23ae42af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/7e9b49ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/16200/16153/c41116cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont Inn and Suites by Wyndham Farmington, MO Farmington 8.0/10 Very good (1006) "Great location" £46 includes taxes & fees 31 Oct - 1 Nov [](https://www.expedia.co.uk/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/668f3d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/c6e7fccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG Perryville 9.4/10 Exceptional (516) "Rooms were clean and everyone was really nice. Only thing I would say is that for the breakfast, the bacon wasn't quite all the way done other than that, a good experience." £88 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (634) "We had a restful stay very safe & clean! Friendly staff:)" £68 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/ac6f4af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau Cape Girardeau 9.4/10 Exceptional (129) "Excellent hotel…" £78 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-23&endDate=2025-10-24®ionId=6058763&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southeast Missouri ### Family friendly things to do in Southeast Missouri Southeast Missouri is a paradise of family-friendly adventures, perfect for those seeking both excitement and quality accommodation. Begin your journey at the stunning Lake of the Ozarks, where you can enjoy a wealth of water activities, from jet skiing to serene boat rides, all while soaking up the sun on sandy beaches. For a taste of nature, the stunning Elephant Rocks State Park invites families to hike among gigantic boulders that seem to defy gravity, providing a unique playground for kids and adults alike. A visit to the Discovery Playhouse in Cape Girardeau offers an interactive experience designed to spark curiosity and creativity in younger travellers, featuring hands-on exhibits that make learning fun. If your family is keen on history, the Missouri Civil War Museum in Cape Girardeau provides an engaging way to explore the region's rich past, with exhibits that captivate all ages. After a day of exploration, consider staying in the charming town of Cape Girardeau, where family-friendly hotels offer convenient access to these attractions and more. Many hotels here pride themselves on attentive service, providing amenities like spacious rooms and complimentary breakfasts, ensuring your family feels pampered during your stay. With easy access to both the natural beauty and cultural heritage of Southeast Missouri, you’ll create lasting memories while enjoying the comforts and quality service that meet your family's high expectations. ## Top Southeast Missouri Hotel Reviews ![Baymont Inn and Suites by Wyndham Farmington, MO](//images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg) ### Baymont Inn and Suites by Wyndham Farmington, MO 10/10 Excellent "It was very nice. There was a problem with me being charge 2 times but that was fix right away" [](https://expedia.co.uk/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The lady that checked me in was amazing!" [](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Love to stay at any Drury. They do things right. Most friendly guest service staff around." [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "The room was very clean. Parking was very easy. Check in was very easy and the staff was great" [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Convenient to St Francis Medical Center. It is quiet, staff is friendly and tge breakfast a plus " [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Motel 6 Poplar Bluff, MO](//images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg) ### Motel 6 Poplar Bluff, MO 10/10 Excellent "Check in was smooth and facilities are excellent " [](https://expedia.co.uk/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Very nice and quiet " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Comfort Inn Festus - St Louis South](//images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc_y.jpg) ### Comfort Inn Festus - St Louis South 10/10 Excellent "The rooms were clean and the beds was nice and comfortable. The staff was friendly and air conditioning it was cold in the room when we got there so it was working. When we're in the area we'll stay there again." [](https://expedia.co.uk/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](//images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70_y.jpg) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South 10/10 Excellent "Great stay! Friendly staff" [](https://expedia.co.uk/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Allenville Hotels](https://www.expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Annapolis Hotels](https://www.expedia.co.uk/Annapolis-Hotels.d6282465.Travel-Guide-Hotels) - [Arcadia Hotels](https://www.expedia.co.uk/Arcadia-Hotels.d6346857.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Arnold](https://www.expedia.co.uk/Arnold-Hotels-Gay-Friendly-Hotel.0-0-d177608-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Pool in Arnold](https://www.expedia.co.uk/Arnold-Hotels-Hotels-With-Pool.0-0-d177608-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Spa Hotels in Arnold](https://www.expedia.co.uk/Arnold-Hotels-Spa-Hotels.0-0-d177608-tSpaHotels.Travel-Guide-Filter-Hotels) - [Belleview Hotels](https://www.expedia.co.uk/Belleview-Hotels.d3000444413.Travel-Guide-Hotels) - [Bismarck Hotels](https://www.expedia.co.uk/Bismarck-Hotels.d553248634983538264.Travel-Guide-Hotels) - [B&B in Black](https://www.expedia.co.uk/Black-Bed-And-Breakfasts.d3000444470-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Black Hotels](https://www.expedia.co.uk/Black-Hotels.d3000444470.Travel-Guide-Hotels) - [Bonne Terre Hotels](https://www.expedia.co.uk/Bonne-Terre-Hotels.d55598.Travel-Guide-Hotels) - [Caledonia Hotels](https://www.expedia.co.uk/Caledonia-Hotels.d6359344.Travel-Guide-Hotels) - [Adults Only Resorts & in Cape Girardeau](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Adults-Only-Resorts.0-0-d820-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Historic Hotels in Cape Girardeau](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Historic-Hotel.0-0-d820-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Centerville Hotels](https://www.expedia.co.uk/Centerville-Hotels.d553248634983078632.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Clayton-Tamm](https://www.expedia.co.uk/Clayton-Tamm-St-Louis-Hotels-Gay-Friendly-Hotel.0-n553248635976473263-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Sports Hotels in Cuba](https://www.expedia.co.uk/Cuba-Hotels-Adventure-Sport-Hotel.0-0-d6499-tAdventureSportHotel.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Cuba](https://www.expedia.co.uk/Cuba-Hotels-Hotels-With-Hot-Tubs.0-0-d6499-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Cuba](https://www.expedia.co.uk/Cuba-Hotels-Luxury-Hotel.0-0-d6499-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Desloge Hotels](https://www.expedia.co.uk/Desloge-Hotels.d55671.Travel-Guide-Hotels) - [Doe Run Hotels](https://www.expedia.co.uk/Doe-Run-Hotels.d3000349343.Travel-Guide-Hotels) - [Ellington Hotels](https://www.expedia.co.uk/Ellington-Hotels.d3000444859.Travel-Guide-Hotels) - [Farmington Hotels](https://www.expedia.co.uk/Farmington-Hotels.d6058764.Travel-Guide-Hotels) - [Wedding Hotels in Fenton](https://www.expedia.co.uk/Fenton-Hotels-Wedding-Hotel.0-0-d7150-tWeddingHotel.Travel-Guide-Filter-Hotels) - [Flat River Hotels](https://www.expedia.co.uk/Flat-River-Hotels.d183474.Travel-Guide-Hotels) - [Fredericktown Hotels](https://www.expedia.co.uk/Fredericktown-Hotels.d55114.Travel-Guide-Hotels) - [Friedheim Hotels](https://www.expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels) - [Glen Allen Hotels](https://www.expedia.co.uk/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Hayti](https://www.expedia.co.uk/Hayti-Hotels-Gay-Friendly-Hotel.0-0-d6058765-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Ironton Hotels](https://www.expedia.co.uk/Ironton-Hotels.d6053585.Travel-Guide-Hotels) - [Hotels near Johnson's Shut-ins State Park](https://www.expedia.co.uk/Johnsons-Shut-Ins-State-Park-Hotels.0-l553248621555612544-0.Travel-Guide-Filter-Hotels) - [Junction City Hotels](https://www.expedia.co.uk/Junction-City-Hotels.d553248634983410095.Travel-Guide-Hotels) - [Leadwood Hotels](https://www.expedia.co.uk/Leadwood-Hotels.d3000349432.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Lemay](https://www.expedia.co.uk/Lemay-Hotels-Gay-Friendly-Hotel.0-0-d3000008297-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Lesterville](https://www.expedia.co.uk/Lesterville-Hotels-Gay-Friendly-Hotel.0-0-d3000445174-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Lesterville Hotels](https://www.expedia.co.uk/Lesterville-Hotels.d3000445174.Travel-Guide-Hotels) - [Marble Hill Hotels](https://www.expedia.co.uk/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels) - [Marquand Hotels](https://www.expedia.co.uk/Marquand-Hotels.d553248634983260789.Travel-Guide-Hotels) - [Hotels with Restaurant in Marston](https://www.expedia.co.uk/Marston-Hotels-Hotel-With-Restaurant.0-0-d55824-thotelwithrestaurant.Travel-Guide-Filter-Hotels) - [Middle Brook Hotels](https://www.expedia.co.uk/Middle-Brook-Hotels.d3000445241.Travel-Guide-Hotels) - [New Offenburg Hotels](https://www.expedia.co.uk/New-Offenburg-Hotels.d3000349478.Travel-Guide-Hotels) - [Park Hills Hotels](https://www.expedia.co.uk/Park-Hills-Hotels.d183485.Travel-Guide-Hotels) - [Perryville Hotels](https://www.expedia.co.uk/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Piedmont Hotels](https://www.expedia.co.uk/Piedmont-Hotels.d3000445413.Travel-Guide-Hotels) - [Pilot Knob Hotels](https://www.expedia.co.uk/Pilot-Knob-Hotels.d3000008143.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Poplar Bluff](https://www.expedia.co.uk/Poplar-Bluff-Hotels-Gay-Friendly-Hotel.0-0-d9449-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Rolla](https://www.expedia.co.uk/Rolla-Hotels-Gay-Friendly-Hotel.0-0-d6058783-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Room Service in Rolla](https://www.expedia.co.uk/Rolla-Hotels-Hotel-With-Room-Service.0-0-d6058783-thotelwithroomservice.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Rolla](https://www.expedia.co.uk/Rolla-Hotels-Hotels-With-Indoor-Pools.0-0-d6058783-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Rolla](https://www.expedia.co.uk/Rolla-Hotels-Pet-Friendly-Hotel.0-0-d6058783-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Sedgewickville Hotels](https://www.expedia.co.uk/Sedgewickville-Hotels.d3000349537.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Sikeston](https://www.expedia.co.uk/Sikeston-Hotels-Gay-Friendly-Hotel.0-0-d6058766-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Sikeston](https://www.expedia.co.uk/Sikeston-Hotels-Hotels-With-Indoor-Pools.0-0-d6058766-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Cheap Hotels in St. James](https://www.expedia.co.uk/St-James-Hotels-Budget-Hotels.0-0-d7592-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Business Hotels in St. James](https://www.expedia.co.uk/St-James-Hotels-Business-Hotel.0-0-d7592-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Hotels with Entertainment in St. James](https://www.expedia.co.uk/St-James-Hotels-Hotel-With-Entertainment.0-0-d7592-thotelwithentertainment.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in St. James](https://www.expedia.co.uk/St-James-Hotels-Hotels-With-Hot-Tubs.0-0-d7592-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in St. James](https://www.expedia.co.uk/St-James-Hotels-Hotels-With-Indoor-Pools.0-0-d7592-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in St. James](https://www.expedia.co.uk/St-James-Hotels-Pet-Friendly-Hotel.0-0-d7592-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in St. James](https://www.expedia.co.uk/St-James-Hotels-Romantic-Hotel.0-0-d7592-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Town and Country](https://www.expedia.co.uk/Town-And-Country-Hotels-Gay-Friendly-Hotel.0-0-d6252549-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Van Buren Hotels](https://www.expedia.co.uk/Van-Buren-Hotels.d183504.Travel-Guide-Hotels) - [Wappapello Hotels](https://www.expedia.co.uk/Wappapello-Hotels.d183505.Travel-Guide-Hotels) - [Weingarten Hotels](https://www.expedia.co.uk/Weingarten-Hotels.d553248635975847364.Travel-Guide-Hotels) - [Gay-Friendly Hotels in West Plains](https://www.expedia.co.uk/West-Plains-Hotels-Gay-Friendly-Hotel.0-0-d6134031-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Williamsville Hotels](https://www.expedia.co.uk/Williamsville-Hotels.d553248634983506457.Travel-Guide-Hotels) - [Flights to Bonne Terre](https://www.expedia.co.uk/Cheap-Flights-To-Bonne-Terre.d55598.Travel-Guide-Flights) - [Flights to Desloge](https://www.expedia.co.uk/Cheap-Flights-To-Desloge.d55671.Travel-Guide-Flights) - [Flights to Park Hills](https://www.expedia.co.uk/Cheap-Flights-To-Park-Hills.d183485.Travel-Guide-Flights) - [Flights to Wappapello](https://www.expedia.co.uk/Cheap-Flights-To-Wappapello.d183505.Travel-Guide-Flights) - [Flights from Park Hills](https://www.expedia.co.uk/lp/flights/183485/flights-from-park-hills) - [Flights from Pilot Knob](https://www.expedia.co.uk/lp/flights/3000008143/flights-from-pilot-knob) - [Flights from Doe Run](https://www.expedia.co.uk/lp/flights/3000349343/flights-from-doe-run) - [Flights from Black](https://www.expedia.co.uk/lp/flights/3000444470/flights-from-black) - [Flights from Lesterville](https://www.expedia.co.uk/lp/flights/3000445174/flights-from-lesterville) - [Flights from Fredericktown](https://www.expedia.co.uk/lp/flights/55114/flights-from-fredericktown) - [Flights from Marquand](https://www.expedia.co.uk/lp/flights/553248634983260789/flights-from-marquand) - [Flights from Zalma](https://www.expedia.co.uk/lp/flights/553248634983373716/flights-from-zalma) - [Flights from Ellsinore](https://www.expedia.co.uk/lp/flights/553248634983439149/flights-from-ellsinore) - [Flights from Bonne Terre](https://www.expedia.co.uk/lp/flights/55598/flights-from-bonne-terre) - [Flights from Farmington](https://www.expedia.co.uk/lp/flights/6058764/flights-from-farmington) - [Flights from Annapolis](https://www.expedia.co.uk/lp/flights/6282465/flights-from-annapolis) - [Flights from Arcadia](https://www.expedia.co.uk/lp/flights/6346857/flights-from-arcadia) - [Flights from Los Angeles (LAX) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/lax/pof/los-angeles-to-poplar-bluff) - [Flights from Carbondale (MDH) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/mdh/pof/carbondale-to-poplar-bluff) - [Flights from Pittsburgh (PIT) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/pit/pof/pittsburgh-to-poplar-bluff) - [Visit Bonne Terre](https://www.expedia.co.uk/Bonne-Terre.dx55598) - [Caledonia Holidays](https://www.expedia.co.uk/Caledonia.d6359344.Holidays-City-Breaks) - [Visit Farmington](https://www.expedia.co.uk/Farmington.dx6058764) - [Visit Fredericktown](https://www.expedia.co.uk/Fredericktown.dx55114) - [Leadwood Holidays](https://www.expedia.co.uk/Leadwood.d3000349432.Holidays-City-Breaks) - [Visit Lesterville](https://www.expedia.co.uk/Lesterville.dx3000445174) - [Van Buren Holidays](https://www.expedia.co.uk/Van-Buren.d183504.Holidays-City-Breaks) - [Car hire Black](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Black.d3000444470.Car-Hire-Guide) - [Hertz Rental Cars in Centerville](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Centerville.d553248634983078632-c40.Car-Rental-Guide-Suppliers) - [Island Car Rentals Rental Cars in Cobalt](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Cobalt.d553248634983153223-c1132.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Belgrade](https://www.expedia.co.uk/Thrifty-Car-Rental-Car-Rentals-In-Belgrade.d553248635975850450-c45.Car-Rental-Guide-Suppliers) - [Doe Run Holiday Rentals](https://www.expedia.co.uk/Doe-Run-Holiday-Rentals.d3000349343.Travel-Guide-HolidayRentals) - [Lesterville Holiday Rentals](https://www.expedia.co.uk/Lesterville-Holiday-Rentals.d3000445174.Travel-Guide-HolidayRentals) - [Pilot Knob Holiday Rentals](https://www.expedia.co.uk/Pilot-Knob-Holiday-Rentals.d3000008143.Travel-Guide-HolidayRentals) - [Book Family-Friendly Hotels in Southeast Missouri on Expedia.com](https://www.expedia.com/Southeast-Missouri-Hotels-Family-Hotel.0-0-d6058763-tFamilyHotel.Travel-Guide-Filter-Hotels)