Find Family-Friendly Hotels in Southeast Missouri, MO

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri Family-Friendly Hotels

Next weekend
In two weeks

Our top choices for Southeast Missouri family-friendly hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,003 reviews)
  • cleanliness
    Children's paradise awaits with splash-worthy indoor and outdoor pools, free breakfast buffet, and family-focused amenities all day long.
The price is £94
includes taxes & fees
10 May - 11 May
Drury Inn & Suites Sikeston, MO

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (177 reviews)
The price is £77
includes taxes & fees
14 May - 15 May
Fairfield Inn & Suites by Marriott Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
  • cleanliness
    A family paradise with splash-worthy fun awaits, where complimentary breakfast and an indoor pool create lasting memories for all ages.
The price is £83
includes taxes & fees
13 May - 14 May
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Year-round family fun with inviting pools and free activities makes this Poplar Bluff inn perfect for kids of all ages.
The price is £78
includes taxes & fees
31 May - 1 Jun
Drury Inn & Suites Poplar Bluff

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (580 reviews)
The price is £85
includes taxes & fees
10 May - 11 May
Holiday Inn Express & Suites Perryville by IHG

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (22 reviews)
The price is £74
includes taxes & fees
17 May - 18 May
Hampton Inn By Hilton Dexter

Hampton Inn Farmington

Hampton Inn Farmington
2.5 star property
Farmington
8.8 out of 10, Excellent, (550 reviews)
  • cleanliness
    Family-friendly destination offers free hot breakfast and indoor pool for all-day swimming and splashing adventures.
The price is £103
includes taxes & fees
3 May - 4 May
Hampton Inn Farmington

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very good, (639 reviews)
The price is £50
includes taxes & fees
31 May - 1 Jun
Super 8 by Wyndham Farmington

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Family-friendly adventures await with free breakfast, cots, and easy access to Cape Splash Aquatic Centre, just minutes away.
The price is £60
includes taxes & fees
24 May - 25 May
Pear Tree Inn Cape Girardeau West

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1,005 reviews)
  • cleanliness
    Seasonal outdoor pool and family-friendly perks create magical memories at this Farmington retreat just minutes from adventure.
The price is £47
includes taxes & fees
2 Jun - 3 Jun
Baymont Inn and Suites by Wyndham Farmington, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at family-friendly hotels in Southeast Missouri

Family-friendly hotels with free breakfast in Southeast Missouri

Family-friendly hotels with pools in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Southeast Missouri

Family friendly things to do in Southeast Missouri

Southeast Missouri is a paradise of family-friendly adventures, perfect for those seeking both excitement and quality accommodation. Begin your journey at the stunning Lake of the Ozarks, where you can enjoy a wealth of water activities, from jet skiing to serene boat rides, all while soaking up the sun on sandy beaches. For a taste of nature, the stunning Elephant Rocks State Park invites families to hike among gigantic boulders that seem to defy gravity, providing a unique playground for kids and adults alike. A visit to the Discovery Playhouse in Cape Girardeau offers an interactive experience designed to spark curiosity and creativity in younger travellers, featuring hands-on exhibits that make learning fun. If your family is keen on history, the Missouri Civil War Museum in Cape Girardeau provides an engaging way to explore the region's rich past, with exhibits that captivate all ages. After a day of exploration, consider staying in the charming town of Cape Girardeau, where family-friendly hotels offer convenient access to these attractions and more. Many hotels here pride themselves on attentive service, providing amenities like spacious rooms and complimentary breakfasts, ensuring your family feels pampered during your stay. With easy access to both the natural beauty and cultural heritage of Southeast Missouri, you’ll create lasting memories while enjoying the comforts and quality service that meet your family's high expectations.

Top Southeast Missouri Hotel Reviews

Explore a world of travel with Expedia