Title: Panama Winery Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy # Search Winery Hotels in Panama - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama Winery Hotels Tonight [27 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [28 Dec - 29 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-12-28&endDate=2025-12-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panama hotels with winery ![Porch](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/b2f4f54b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/10e0f18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/bbcb2215.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/b45845d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gatto Blanco Party Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Gatto-Blanco-Party-Hotel.h6443494.Hotel-Information) Casco Viejo 6.2/10 (30) "Too noisy from bar above. They have installed noise doors on the 2nd floor to prevent the music from the bar to get to the rooms on that floor; however, on the first floor they don’t have them. Also, the patrons from the bar go up and down the stairs all night, shouting and laughing. Having those doors can make your guests visit more enjoyable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ernesto [](https://www.expedia.co.uk/Panama-City-Hotels-Gatto-Blanco-Party-Hotel.h6443494.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-10&endDate=2026-01-11®ionId=142&adults=2&location_highlights_explore=winery&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Winery-Hotels.0-0-d142-tWineryHotels.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Winery-Hotels.0-0-d142-tWineryHotels.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "I will definitely be back ! " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Novotel Panama City](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "Bien ubicado bien servicio " [](https://expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Yes" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3837h2557x3y3-241f7e7d_y.jpg) ### Hyatt Regency Panama City 10/10 Excellent "Amazing!!! " [](https://expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "All" [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "Great hotel in Panama for both short and long stays, with super friendly, warm, and helpful staff who bring a lot of positive energy to the experience, and the colorful design makes the place feel lively and welcoming. I ended up here unexpectedly after getting stuck in Panama due to visa issues, and I was really lucky to find a hotel that recognized my VIP status, checked me in very early in the morning, and supported me when I needed it. Communication was easy since most of the staff speak some English, breakfast offered a nice mix of local and international options, and overall service was excellent. There’s still some room for improvement in room maintenance (like a few lights not working and the desk chair needing replacement), but the room itself was very spacious with great city views." [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "Will kept hotel. Great for the price. " [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "staff and food are amazing " [](https://expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Room was very nice, staff couldn't be friendlier, they were super nice 👍 " [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information)