Title: Panama Gay-Friendly Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Gay-Friendly-Hotel.0-0-d2897-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Adobe](https://images.trvl-media.com/place/6023445/756687f1-f5d2-4c5e-80bf-e3d7aa95a03c.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.co.uk/Bocas-Del-Toro-Hotels-Gay-Friendly-Hotel.0-0-d6023445-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Idyllic Sunset at Playa Blanca, Panama](https://images.trvl-media.com/place/6246042/058a4e01-e481-4197-9791-26c53b4ee917.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Rio Hato [](https://expedia.co.uk/Rio-Hato-Hotels-Gay-Friendly-Hotel.0-0-d6246042-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Sunrise with a view at Volcán Barú in Panama](https://images.trvl-media.com/place/500194/a9fdba1c-ad36-4683-90ac-2cdb584e103b.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Boquete [](https://expedia.co.uk/Boquete-Hotels-Gay-Friendly-Hotel.0-0-d500194-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Colon [](https://expedia.co.uk/Colon-Hotels-Gay-Friendly-Hotel.0-0-d601867-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Traditional dances of the state of Veracruz Mexico, typical clothes.](https://images.trvl-media.com/place/6360124/8b5bd5dc-d1e8-4f62-8efa-6c53ea07e013.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Veracruz [](https://expedia.co.uk/Veracruz-Hotels-Gay-Friendly-Hotel.0-0-d6360124-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Flowering plant on meadow in golden light of sunset on the hillside of El Valle de Anton with mountain tops in background](https://images.trvl-media.com/place/6053180/2dca6365-7ad6-4f68-9dc1-9fa32bb57eda.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### El Valle de Anton [](https://expedia.co.uk/El-Valle-De-Anton-Hotels-Gay-Friendly-Hotel.0-0-d6053180-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![Adobe](https://images.trvl-media.com/place/6053184/fef85501-8014-492d-aede-9500c1e1b289.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Tocumen [](https://expedia.co.uk/Tocumen-Hotels-Gay-Friendly-Hotel.0-0-d6053184-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ## Check availability on Panama Gay-Friendly Hotels Tonight [1 Feb - 2 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-01&endDate=2026-02-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Tomorrow [2 Feb - 3 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-02&endDate=2026-02-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Next weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) In two weeks [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) ## Our top choices for Panama LGBT-friendly hotels ![2 bars/lounges, gastropub](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/f3b8e5d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine ](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/6db7ada6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/d27e0b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, gastropub](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/8e100c2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Urban Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) Bella Vista 8.8/10 Excellent (1,051 reviews) "Clean spacious room and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie £68 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-15&endDate=2026-02-16®ionId=142&adults=2&travelerType=lgbtq_welcoming&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Gay-Friendly-Hotel.0-0-d142-tGayFriendlyHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Gay-Friendly-Hotel.0-0-d142-tGayFriendlyHotel.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Always great value for the price!" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/68ce59ee_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Nice stuff. Very welcoming and cheerful people. Clean. Closhopping centers " [](https://expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The first room was clean but the window has moisture in between the panel so you can’t see outside. The next day I told the front desk and they rectified it by moving us to a different room with no hustle " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "The room was very comfortable, air-condition worked great. " [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "The location was terrific making it easy to catch an Uber to pretty much anywhere you wanted to go. Pool & fitness area were as expected & the room was comfortable. We were here for 4 nights. Loved that it was attached to the mall." [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Room was clean and check in was quick. Literally right next to the airport so it is perfect for a layover " [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Room was great, excellent view, clean and spacious." [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "They stay were extremely courteous to us. A little delayed check in but we were able to store our luggage and use their facilities. El Panama is one of my favorite places to stay… so many memories here. " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3837h2557x3y3-241f7e7d_y.jpg) ### Hyatt Regency Panama City 10/10 Excellent "room was lovely, staff was excellent" [](https://expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information)