Title: Panama Gay-Friendly Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing a beach, landscape views and tropical scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25691-Panama.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Gay-Friendly Hotels in Panama - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Gay-Friendly-Hotel.0-0-d2897-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/1d8a91c9ba3e2729b384542dbcd5f2f4.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Colon [](https://expedia.co.uk/Colon-Hotels-Gay-Friendly-Hotel.0-0-d601867-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/2/504facaece8a8de4b5e66a51bfdb8196.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### El Valle de Anton [](https://expedia.co.uk/El-Valle-De-Anton-Hotels-Gay-Friendly-Hotel.0-0-d6053180-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/b0242759ce82d4f0d6f5123d7c510e46.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Rio Hato [](https://expedia.co.uk/Rio-Hato-Hotels-Gay-Friendly-Hotel.0-0-d6246042-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/2/574fdc356550d0576f79446242a4959c.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Los Naranjos [](https://expedia.co.uk/Los-Naranjos-Hotels-Gay-Friendly-Hotel.0-0-d553248623140007074-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/25f99a393b969b3735c64d4b492225c8.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.co.uk/Bocas-Del-Toro-Hotels-Gay-Friendly-Hotel.0-0-d6023445-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/e5351721da1afb1df3e5fd26652899ae.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### David [](https://expedia.co.uk/David-Hotels-Gay-Friendly-Hotel.0-0-d500195-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) ## Check availability on Panama Gay-Friendly Hotels Tonight [1 Nov - 2 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-11-01&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Tomorrow [2 Nov - 3 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Next weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) In two weeks [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) ## Top Panama Gay-Friendly Hotels ![2 bars/lounges, gastropub](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/f3b8e5d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/c5a4778b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/f3db3ea4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/a60edef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Urban Hotel Bella Vista 8.8/10 Excellent (1053) "The room was very comfortable and clean. Great restaurants and service. I would stay here again " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Kelli £64 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16®ionId=142&adults=2&travelerType=lgbtq_welcoming&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Gay-Friendly-Hotel.0-0-d142-tGayFriendlyHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Gay-Friendly-Hotel.0-0-d142-tGayFriendlyHotel.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Plaza Paitilla Inn Hotel](//images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "Clean room, excelent breakfast, good driver for the transportation, excellent staff, very kind" [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Principe Hotel and Suites](//images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Excellent service " [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Central Hotel Panama Casco Viejo](//images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg) ### Central Hotel Panama Casco Viejo 10/10 Excellent "Staffs were wonderful." [](https://expedia.co.uk/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "It was a nice property" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![The Westin Playa Bonita Panama](//images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/f767a768_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "We had an amazing family vacation. Especial mention for very exceptional people such as Franklin who is the best taxi driver and tour guy that you can get and Maria, who provides a personalized customer service in the buffet. They made our vacation unforgettable. They definitely upgrade any experience. " [](https://expedia.co.uk/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Megapolis Hotel Panamá](//images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "Na" [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The place was clean n always fresh , definitely my place to go whenever I come back to Panama. Love every bit of my stay " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "The rooms were amazing " [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Arcadia Condo Suites](//images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534_y.jpg) ### Arcadia Condo Suites 10/10 Excellent "The property was excellent the safe was very helpful I gave the staff 5 star but overall I would stay there 10 time over again " [](https://expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information)