Title: Panama Boutique Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy # Search Boutique Hotels in Panama - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Boutique-Hotel.0-0-d2897-tBoutiqueHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/25f99a393b969b3735c64d4b492225c8.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.co.uk/Bocas-Del-Toro-Hotels-Boutique-Hotel.0-0-d6023445-tBoutiqueHotel.Travel-Guide-Filter-Hotels) ## Check availability on Panama Boutique Hotels Tonight [12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-12&endDate=2026-01-13&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Jan - 14 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-13&endDate=2026-01-14&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2026-01-23&endDate=2026-01-25&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panama boutique hotels ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/570000/569200/569127/4bcbc857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/570000/569200/569127/28d0a992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/570000/569200/569127/a3d7a169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/570000/569200/569127/19652dba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### De Ville Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-De-Ville-Hotel.h569127.Hotel-Information) Bella Vista 8.2/10 Very good (562 reviews) "The first day the front desk attendant charged me $45 he said I did not have a reservation. I had to talk to someone else and I though I got my money back, it was a bad first impression. AC was not working properly, the small fridge was not working right and it tool a couple of days to get it replaced. They had a toaster connected to an electrical extension and the breaker will not stay on. I got ill and needed to come back before. I liked Panama, people very friendly, but I know I will never... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gerardo [](https://www.expedia.co.uk/Panama-City-Hotels-De-Ville-Hotel.h569127.Hotel-Information) ![Daily continental breakfast (USD 10 per person)](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/a55dea03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, Balcony | View from room](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/6995bb0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/b45845d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/bbcb2215.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gatto Blanco Party Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Gatto-Blanco-Party-Hotel.h6443494.Hotel-Information) Casco Viejo 6.2/10 (30 reviews) "Too noisy from bar above. They have installed noise doors on the 2nd floor to prevent the music from the bar to get to the rooms on that floor; however, on the first floor they don’t have them. Also, the patrons from the bar go up and down the stairs all night, shouting and laughing. Having those doors can make your guests visit more enjoyable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ernesto [](https://www.expedia.co.uk/Panama-City-Hotels-Gatto-Blanco-Party-Hotel.h6443494.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/7000000/6350000/6349300/6349280/04301af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/7000000/6350000/6349300/6349280/597c7a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/7000000/6350000/6349300/6349280/65cc8b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/7000000/6350000/6349300/6349280/da8af35d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Establos Boutique Resort- All Inclusive [](https://www.expedia.co.uk/Boquete-Hotels-Los-Establos-Boutique-Hotel-All-Inclusive.h6349280.Hotel-Information) Jaramillo 9.6/10 Exceptional (21 reviews) "Very beautiful and special place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) SVETLANA £434 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Boquete-Hotels-Los-Establos-Boutique-Hotel-All-Inclusive.h6349280.Hotel-Information) ![Presidential Suite, 1 Bedroom, Beach View | Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2120000/2113400/2113376/6acdb77f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ecotours](https://images.trvl-media.com/lodging/3000000/2120000/2113400/2113376/92525924.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2120000/2113400/2113376/w1170h2080x0y226-e13ad64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom, Beach View | Terrace/patio](https://images.trvl-media.com/lodging/3000000/2120000/2113400/2113376/0d1ce10d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Playa Tortuga Hotel Beach And Resort [](https://www.expedia.co.uk/Bocas-Del-Toro-Hotels-Playa-Tortuga-Hotel-Beach-And-Resort.h2113376.Hotel-Information) Bocas del Toro 7.6/10 Good (446 reviews) "Great spot friendly staff!!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) William [](https://www.expedia.co.uk/Bocas-Del-Toro-Hotels-Playa-Tortuga-Hotel-Beach-And-Resort.h2113376.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/86dd447e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Yoga](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/79b76059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) Bella Vista 9.4/10 Exceptional (1,002 reviews) "All was perfect for our Christmas vacation - staff food and rooms - would definitely stay here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) PROBIR MAYUR £160 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/5ba20b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/0f538272.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/a3824af3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/27481125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Casa Panamá [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Casa-Panama.h12091977.Hotel-Information) Casco Viejo 7.4/10 Good (603 reviews) "Location is absolutely amazing" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £57 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Casa-Panama.h12091977.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4070000/4061500/4061472/03c94141.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Twin Room-Terrace-Garden View | View from room](https://images.trvl-media.com/lodging/5000000/4070000/4061500/4061472/49b8b5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/5000000/4070000/4061500/4061472/41249dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4070000/4061500/4061472/02c606e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Haven and Spa - Health and Wellness Accommodation - Adults Only [](https://www.expedia.co.uk/Boquete-Hotels-The-Haven-And-Spa-Health-And-Wellness-Accommodation-Adults-Only.h4061472.Hotel-Information) Boquete 9.0/10 Wonderful (174 reviews) "Definitely a mountaintop heaven." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patrick [](https://www.expedia.co.uk/Boquete-Hotels-The-Haven-And-Spa-Health-And-Wellness-Accommodation-Adults-Only.h4061472.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5460000/5451800/5451750/21d9edb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5460000/5451800/5451750/af95f4fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | 1 bedroom, hypo-allergenic bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/6000000/5460000/5451800/5451750/1cdef7a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch served; international cuisine, al fresco dining ](https://images.trvl-media.com/lodging/6000000/5460000/5451800/5451750/05412b8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Saba Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-The-Saba-Hotel.h5451750.Hotel-Information) Bella Vista 8.2/10 Very good (420 reviews) "This property is in a good location. Good hotel for the price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Panama-City-Hotels-The-Saba-Hotel.h5451750.Hotel-Information) ![Lunch and dinner served, local cuisine](https://images.trvl-media.com/lodging/2000000/1790000/1784600/1784534/00c1fcb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Master) | Egyptian cotton sheets, in-room safe, individually decorated, desk](https://images.trvl-media.com/lodging/2000000/1790000/1784600/1784534/d3769484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1790000/1784600/1784534/0d793b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1790000/1784600/1784534/d55fc1e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverside Inn [](https://www.expedia.co.uk/Boquete-Hotels-The-Riverside-Inn.h1784534.Hotel-Information) Los Naranjos 9.6/10 Exceptional (112 reviews) "Staff was excellent, food was delicious, and room very comfy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carolina £186 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Boquete-Hotels-The-Riverside-Inn.h1784534.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/6bf7a38f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a76722fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a7b09037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Garden Area](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a69675a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Manrey Boutique Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Manrey-Boutique-Hotel.h4051305.Hotel-Information) Panama City 7.6/10 Good (255 reviews) "Hotel was closed when we arrived. Had not told us about the closure so we had to scramble to find another hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Panama-City-Hotels-Manrey-Boutique-Hotel.h4051305.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-26&endDate=2026-01-27®ionId=142&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Boutique-Hotel.0-0-d142-tBoutiqueHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Boutique-Hotel.0-0-d142-tBoutiqueHotel.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "The property was in a beautiful spot with a gorgeous of the ocean. The water recedes in the day but don’t worry it comes back by the morning. The food is good - good variety. One thing I will point out. Bring your insect repellant. There are microscopic insects (mosquitoes) that come out from 6pm-6am that you will not see or feel when they bite you until the next day when you start to itch the bites. After bite is also a must. Other than that we had the best time! " [](https://expedia.co.uk/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3837h2557x3y3-241f7e7d_y.jpg) ### Hyatt Regency Panama City 10/10 Excellent "excellent rooms, great and pleasurable staff, great main restaurant, good location, I used a rental car for 4 days and the valet parking service was great " [](https://expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Yes" [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Hotel bien ubicado, cerca a cinta costera. El hotel cuenta con personal amable y ocupado del bienestar de los huespedes. Areas comunes en muy buen estado. Cuenta con servicio de restaurante a precios adecuados" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Clean room" [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "The staff were very polite and helpful and the room was quite nice. Its my second trip to panama and my second time staying at the hotel. It will always be my place to stay" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "The room was very nice with wrap around windows to see the skyline. Beds comfortable, breakfast was very good." [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "5 🌟 " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Staff was very helpful. Shuttle was very convenient and on time Food was great and hotel was clean. Will stay again " [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)