Title: Panama Boutique Hotels, Mexico and Central America: Panama Hotel Guide | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Holiday Rentals in Panama](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing a beach, landscape views and tropical scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25691-Panama.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in Panama ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Hotels-Boutique-Hotel.0-0-d2897-tBoutiqueHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/25f99a393b969b3735c64d4b492225c8.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.co.uk/Bocas-Del-Toro-Hotels-Boutique-Hotel.0-0-d6023445-tBoutiqueHotel.Travel-Guide-Filter-Hotels) ## Check availability on Panama Boutique Hotels Tonight [9 Oct - 10 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-10-09&endDate=2025-10-10&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-10-10&endDate=2025-10-11&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=142&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panama Boutique Hotels ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/570000/569200/569127/4bcbc857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/569200/569127/01c921bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/570000/569200/569127/19652dba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/570000/569200/569127/cc2a9415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### De Ville Hotel Bella Vista 8.2/10 Very good (562) "The first day the front desk attendant charged me $45 he said I did not have a reservation. I had to talk to someone else and I though I got my money back, it was a bad first impression. AC was not working properly, the small fridge was not working right and it tool a couple of days to get it replaced. They had a toaster connected to an electrical extension and the breaker will not stay on. I got ill and needed to come back before. I liked Panama, people very friendly, but I know I will never... [](https://www.expedia.co.uk/Panama-City-Hotels-De-Ville-Hotel.h569127.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/b2f4f54b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, Balcony | View from room](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/2ea17901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/b45845d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/7000000/6450000/6443500/6443494/10e0f18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gatto Blanco Party Hotel Casco Viejo 6.2/10 (30) "Too noisy from bar above. They have installed noise doors on the 2nd floor to prevent the music from the bar to get to the rooms on that floor; however, on the first floor they don’t have them. Also, the patrons from the bar go up and down the stairs all night, shouting and laughing. Having those doors can make your guests visit more enjoyable." [](https://www.expedia.co.uk/Panama-City-Hotels-Gatto-Blanco-Party-Hotel.h6443494.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/7000000/6350000/6349300/6349280/04301af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Body treatments, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/7000000/6350000/6349300/6349280/1c8432b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/7000000/6350000/6349300/6349280/47bd15bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/7000000/6350000/6349300/6349280/778d687d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Establos Boutique Resort- All Inclusive Jaramillo 9.6/10 Exceptional (21) "Very beautiful and special place." £530 includes taxes & fees 1 Nov - 2 Nov [](https://www.expedia.co.uk/Boquete-Hotels-Los-Establos-Boutique-Hotel-All-Inclusive.h6349280.Hotel-Information) ![Presidential Suite, 1 Bedroom, Beach View | Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2120000/2113400/2113376/6acdb77f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom, Beach View | Living area | 32-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/3000000/2120000/2113400/2113376/46303350.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2120000/2113400/2113376/2dacf79c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sailing, kayaking, motor boating](https://images.trvl-media.com/lodging/3000000/2120000/2113400/2113376/55017729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Playa Tortuga Hotel Beach And Resort Bocas del Toro 7.6/10 Good (445) "Great spot friendly staff!!" [](https://www.expedia.co.uk/Bocas-Del-Toro-Hotels-Playa-Tortuga-Hotel-Beach-And-Resort.h2113376.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/c4347824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Classic, 1 King Bed, Non-Smoking | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8ec9f171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel Bella Vista 9.2/10 Wonderful (1005) "We had an amazing time, great hotel and great breakfast. " £151 includes taxes & fees 8 Nov - 9 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/6488c648.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/cc9dda07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/27481125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | Bathroom | Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/aceb9cf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Casa Panamá Casco Viejo 7.4/10 Good (573) "The Top Roof Music, the music is very loud in the rooms on the second floor." £50 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Casa-Panama.h12091977.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/5000000/4070000/4061500/4061472/97f64142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/5000000/4070000/4061500/4061472/f7548151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Twin Room-Terrace-Garden View | View from room](https://images.trvl-media.com/lodging/5000000/4070000/4061500/4061472/49b8b5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Room With Terrace - Parking Lot View | Terrace/patio](https://images.trvl-media.com/lodging/5000000/4070000/4061500/4061472/a35e1bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Haven and Spa - Health and Wellness Accommodation - Adults Only Boquete 9.0/10 Wonderful (174) [](https://www.expedia.co.uk/Boquete-Hotels-The-Haven-And-Spa-Health-And-Wellness-Accommodation-Adults-Only.h4061472.Hotel-Information) ![Standard Room, 2 Queen Beds | 1 bedroom, hypo-allergenic bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/6000000/5460000/5451800/5451750/1693e9ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5460000/5451800/5451750/c8e1bb28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/6000000/5460000/5451800/5451750/4f390dd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/6000000/5460000/5451800/5451750/7fe62689.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Saba Hotel Bella Vista 8.2/10 Very good (420) "This property is in a good location. Good hotel for the price." [](https://www.expedia.co.uk/Panama-City-Hotels-The-Saba-Hotel.h5451750.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1790000/1784600/1784534/a72ef925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1790000/1784600/1784534/1693c223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, local cuisine](https://images.trvl-media.com/lodging/2000000/1790000/1784600/1784534/00c1fcb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1790000/1784600/1784534/92287161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverside Inn Los Naranjos 9.6/10 Exceptional (111) "Our favorite hotel in Boquete. Great rooms, great service. Superb restaurant." £106 includes taxes & fees 22 Oct - 23 Oct [](https://www.expedia.co.uk/Boquete-Hotels-The-Riverside-Inn.h1784534.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/6bf7a38f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a76722fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a7b09037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Garden Area](https://images.trvl-media.com/lodging/5000000/4060000/4051400/4051305/a69675a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Manrey Boutique Hotel Panama City 7.6/10 Good (255) [](https://www.expedia.co.uk/Panama-City-Hotels-Manrey-Boutique-Hotel.h4051305.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-23&endDate=2025-10-24®ionId=142&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Boutique-Hotel.0-0-d142-tBoutiqueHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama-Boutique-Hotel.0-0-d142-tBoutiqueHotel.Hotel-Filter-Destinations) ## Top Panama Hotel Reviews ![Megapolis Hotel Panamá](//images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "Spacious and convenient " [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Principe Hotel and Suites](//images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Comfortable and affordable " [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Waymore Hotel Spa & Casino](//images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "I love this hotel, the breakfast is great, the hotel room spacious and clean. Having a Casino and night club right in your hotel is s super plus. The staff is very friendly snd helpful. The maid service is excellent and the room service team is always on point." [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "The experience was very beautiful from the room to the views at the pool. Customer service excellent and respectful and courteous. They made my birthday wonderful." [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](//images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "From greeting at the front, helpful checkin, great service in restaurants to pickup of our luggage when leaving, fabulous" [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Room service and bar food needs to improve" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Didn’t use the gym" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Novotel Panama City](//images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "Love the great stretch of restaurants nearby, within walkable distance" [](https://expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Marriott Panama Hotel](//images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Helpfull staff" [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)