Title: Missouri Spa Hotels, United States of America: Missouri Hotel Guide | Expedia.co.uk [Missouri Travel Guide](https://expedia.co.uk/Missouri.dx227)[Missouri Hotels](https://expedia.co.uk/Destinations-In-Missouri.d227.Hotel-Destinations)[Holiday Rentals in Missouri](https://expedia.co.uk/Destinations-In-Missouri.d227.Holiday-Rental-Destinations)[Missouri Flights](https://expedia.co.uk/Destinations-In-Missouri.d227.Flight-Destinations)[Missouri Car Hire](https://expedia.co.uk/Destinations-In-Missouri.d227.Car-Hire-Destinations)[Missouri Holidays](https://expedia.co.uk/Missouri.d227.Holidays-City-Breaks) ![Meeting of the Waters Fountain featuring a fountain](https://images.trvl-media.com/place/553248621555612576/69db9636-3749-4b96-a948-2ec092fa369d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Spa Hotels in Missouri - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Missouri Accommodation: Most Popular Cities to Stay ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/478000/478466-Saint-Louis.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### St. Louis [](https://expedia.co.uk/St-Louis-Hotels-Spa-Hotels.0-0-d178309-tSpaHotels.Travel-Guide-Filter-Hotels) ![Missouri State Capitol which includes an administrative building, a fountain and heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/257000/257633-Missouri.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Columbia [](https://expedia.co.uk/Columbia-Hotels-Spa-Hotels.0-0-d901-tSpaHotels.Travel-Guide-Filter-Hotels) ## Check availability on Missouri Spa Hotels Tonight [21 Dec - 22 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=227&startDate=2025-12-21&endDate=2025-12-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Dec - 23 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=227&startDate=2025-12-22&endDate=2025-12-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=227&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=227&startDate=2026-01-02&endDate=2026-01-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Missouri hotels with a spa ![Couples treatment room(s), hot tub, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/120000/119400/119325/2e8a9867.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), hot tub, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/120000/119400/119325/b28e1733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/120000/119400/119325/449627c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/119400/119325/2b74a611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Elms Hotel & Spa, a Destination by Hyatt Hotel [](https://www.expedia.co.uk/Kansas-City-Hotels-The-Elms-Hotel-Spa.h119325.Hotel-Information) Excelsior Springs 8.6/10 Excellent (1002) "Wonderful spa! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £133 includes taxes & fees 19 Jan - 20 Jan 2026 [](https://www.expedia.co.uk/Kansas-City-Hotels-The-Elms-Hotel-Spa.h119325.Hotel-Information) ![Couples treatment room(s), body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/7d41cdab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine ](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/926b808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite (Two Double Beds) | Terrace/patio](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/1773a780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa [](https://www.expedia.co.uk/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) Lake Ozark 9.0/10 Wonderful (1001) "Awesome staff, great food and service!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori [](https://www.expedia.co.uk/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Couples treatment room(s), hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/56a41562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/5b370fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/941b0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/89e020ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel St Louis [](https://www.expedia.co.uk/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) Downtown St. Louis 9.4/10 Exceptional (1001) "Everything exceeded my expectations from the welcoming staff to the luxuriously appointed room, to the 4 feet deep bathtub in which to soak my cares away--it was a total dream come true. I would come back in a heartbeat at this home away from home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynne £363 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout curtains, iron/ironing board, travel cot, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/83344a11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/e7bd5e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/a7d33a02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Lake Resort Lake of the Ozarks [](https://www.expedia.co.uk/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) Osage Beach 8.4/10 Very good (1000) "My family and I had a wonderful time staying at this resort. The staff were very welcoming and helpful, and the rooms and facilities were all great. We really enjoyed our stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amos £104 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/2000000/1140000/1131200/1131105/68f4810e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1140000/1131200/1131105/5f685c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1140000/1131200/1131105/d87b50c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/2000000/1140000/1131200/1131105/69484ccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton St. Louis St. Charles [](https://www.expedia.co.uk/St-Louis-Hotels-Embassy-Suites-St-Louis-St-Charles.h1131105.Hotel-Information) St. Charles 8.8/10 Excellent (1014) "I Loved it I would definitely stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roberta £105 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Embassy-Suites-St-Louis-St-Charles.h1131105.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/78b2a688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/56fc52a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/3c6c1cf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/e2ffcacf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel St. Louis at the Arch [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) Downtown St. Louis 9.4/10 Exceptional (3283) "Our stay was very enjoyable. Location was great and kids loved the indoor pool!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christy £118 includes taxes & fees 26 Dec - 27 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/3721d666.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/e4de4f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/ea805e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency St. Louis at The Arch [](https://www.expedia.co.uk/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) Downtown St. Louis 8.4/10 Very good (4030) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn £87 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/1000000/20000/17600/17599/ff4ffddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17600/17599/e1c9e824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17600/17599/8ba6c79d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/20000/17600/17599/a029e58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Clayton/St. Louis-Galleria Area [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-Suites-ClaytonSt-Louis-Galleria-Area.h17599.Hotel-Information) Clayton 9.0/10 Wonderful (915) "Clean room, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patrick George £100 includes taxes & fees 19 Jan - 20 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-Suites-ClaytonSt-Louis-Galleria-Area.h17599.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/a7778b87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/3ac9f95d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/876246e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/b11945d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Arnold [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Arnold.h3861101.Hotel-Information) Arnold 9.6/10 Exceptional (1000) "Clean room, comfortable bed, free breakfast, dinner and drinks every night! We had a great stay, will definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacqueline £106 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Arnold.h3861101.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/ad47a940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/b1e08b2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/b4171890.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/b614d7da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West [](https://www.expedia.co.uk/St-Louis-Hotels-Homewood-Suites-By-Hilton-St-Louis-Riverport-Airport-West.h1658956.Hotel-Information) Maryland Heights 7.4/10 Good (1009) "Spacious suite, friendly staff. Check in was easy and everything looked clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan £56 includes taxes & fees 6 Jan - 7 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-Homewood-Suites-By-Hilton-St-Louis-Riverport-Airport-West.h1658956.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-04&endDate=2026-01-05®ionId=227&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Missouri-Spa-Hotels.0-0-d227-tSpaHotels.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Missouri-Spa-Hotels.0-0-d227-tSpaHotels.Hotel-Filter-Destinations) ## Top Missouri Hotel Reviews ![Thousand Hills Resort Hotel](https://images.trvl-media.com/lodging/91000000/90270000/90264500/90264487/7df41ed5_y.jpg) ### Thousand Hills Resort Hotel 10/10 Excellent "the room was clean." [](https://expedia.co.uk/Branson-Hotels-Thousand-Hills-Resort-Hotel.h90264487.Hotel-Information) ![Stoney Creek Hotel Kansas City - Independence](https://images.trvl-media.com/lodging/10000000/9730000/9724700/9724606/261f0ada_y.jpg) ### Stoney Creek Hotel Kansas City - Independence 10/10 Excellent "Great place for us to stay with two dogs, lots of food and options around. Good grounds for the dogs, and nice staff. Would stay here again " [](https://expedia.co.uk/Kansas-City-Hotels-Stoney-Creek-Hotel-Kansas-City-Independence.h9724606.Hotel-Information) ![Orangewood Inn & Suites Kansas City Airport](https://images.trvl-media.com/lodging/1000000/10000/8600/8523/f51a002b_y.jpg) ### Orangewood Inn & Suites Kansas City Airport 10/10 Excellent "Very nice and clean. " [](https://expedia.co.uk/Kansas-City-Hotels-SureStay-Plus-Hotel-By-Best-Western-Kansas-City-Airport.h8523.Hotel-Information) ![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/78b2a688_y.jpg) ### Drury Plaza Hotel St. Louis at the Arch 10/10 Excellent "All is perfect except room cleanse " [](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) ![Chateau On The Lake Resort Spa and Convention Center](https://images.trvl-media.com/lodging/1000000/60000/58200/58161/b48c4676_y.jpg) ### Chateau On The Lake Resort Spa and Convention Center 10/10 Excellent "From the time we drove up until we left everyone was awesome. This was our first time staying here however it will not be our last. Daniel the bellman/valet guy was the best!!! " [](https://expedia.co.uk/Branson-Hotels-Chateau-On-The-Lake-Resort-Spa-And-Convention-Center.h58161.Hotel-Information) ![The Stone Castle Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/130000/120200/120196/7690740a_y.jpg) ### The Stone Castle Hotel & Conference Center 10/10 Excellent "Good breakfast Clean room" [](https://expedia.co.uk/Branson-Hotels-The-Stone-Castle-Hotel-Conference-Center.h120196.Hotel-Information) ![Hyatt Vacation Club at The Lodges at Timber Ridge, Branson](https://images.trvl-media.com/lodging/3000000/2380000/2370700/2370647/db84b0fa_y.jpg) ### Hyatt Vacation Club at The Lodges at Timber Ridge, Branson 10/10 Excellent "Room clean. Staff responsive to needs. " [](https://expedia.co.uk/Branson-Hotels-Lodges-At-Timber-Ridge-By-Welk-Resorts.h2370647.Hotel-Information) ![Ameristar Casino Hotel Kansas City](https://images.trvl-media.com/lodging/1000000/50000/41600/41546/ad53926e_y.jpg) ### Ameristar Casino Hotel Kansas City 10/10 Excellent "The lady at the front desk was very friendly and courteous." [](https://expedia.co.uk/Kansas-City-Hotels-Ameristar-Casino-Hotel-Kansas-City.h41546.Hotel-Information) ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 10/10 Excellent "Good " [](https://expedia.co.uk/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [Apache Flats Hotels ](https://www.expedia.co.uk/Apache-Flats-Hotels.d553248635975850469.Travel-Guide-Hotels) - [Ashland Hotels ](https://www.expedia.co.uk/Ashland-Hotels.d3000421361.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Boonville ](https://www.expedia.co.uk/Boonville-Hotels-Gay-Friendly-Hotel.0-0-d6775-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Buckingham Estates ](https://www.expedia.co.uk/Buckingham-Estates-Camdenton-Hotels-Gay-Friendly-Hotel.0-n553248635976481574-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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