Search Spa Hotels in Missouri

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Missouri Accommodation: Most Popular Cities to Stay

Check availability on Missouri Spa Hotels

This weekend
Next weekend

Our top choices for Missouri hotels with a spa

The Elms Hotel & Spa, a Destination by Hyatt Hotel

The Elms Hotel & Spa, a Destination by Hyatt Hotel
4.0 star property
Excelsior Springs
8.8 out of 10, Excellent, (1,004 reviews)
  • cleanliness
    Immerse in a rejuvenating spa retreat with 17 treatment rooms, hot tubs, and beautiful garden views at this historic hotel.
"I love the hot tub, coffee shop, and restaurant/tavern areas."
United States
Nicholas
The price is £146
includes taxes & fees
4 Jun - 5 Jun
The Elms Hotel & Spa, a Destination by Hyatt Hotel

Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
4.0 star property
Lake Ozark
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Relax at this lakeside resort with four treatment rooms at Spa 54, featuring hot stone massages, hydrotherapy, and couples' services.
"All amenities were available except the pool due to the weather"
United States
Shantel
The price is £135
includes taxes & fees
10 May - 11 May
Camden on the Lake Resort & Spa

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
"I would definitely come back here to rest and recharge."
United States
Lynne
The price is £289
includes taxes & fees
7 May - 8 May
Four Seasons Hotel St Louis

Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks
3.0 star property
Osage Beach
8.4 out of 10, Very good, (1,001 reviews)
  • cleanliness
    Lakeside spa resort with golf course offers rejuvenating massages, body treatments, and poolside relaxation.
"The spa was extremely friendly and helpful."
United States
Rochelle
The price is £141
includes taxes & fees
11 May - 12 May
Margaritaville Lake Resort Lake of the Ozarks

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,003 reviews)
"We enjoyed several hours in the pool and hot tub."
United States
Robin D
The price is £124
includes taxes & fees
17 May - 18 May
Embassy Suites by Hilton St. Louis St. Charles

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (3,405 reviews)
"The pool and hot tubs were big hits for the kids"
United States
Eric
The price is £140
includes taxes & fees
21 May - 22 May
Drury Plaza Hotel St. Louis at the Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,053 reviews)
"Getting to room was like a corn maze and a pool would be nice, or hot tub."
United States
Mike
The price is £110
includes taxes & fees
25 May - 26 May
Hyatt Regency St. Louis at The Arch

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
Clayton
9.0 out of 10, Wonderful, (977 reviews)
"Pool clean."
United States
kathyrn
The price is £113
includes taxes & fees
10 May - 11 May
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1,003 reviews)
"Clean room nice whirl tub. Staff was very professional "
United States
Shane
The price is £107
includes taxes & fees
17 May - 18 May
Drury Inn & Suites St. Louis Arnold

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Maryland Heights
7.6 out of 10, Good, (1,009 reviews)
"The pool was clean and fun."
United States
Alissa
The price is £87
includes taxes & fees
13 May - 14 May
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Missouri Hotel Reviews

Explore a world of travel with Expedia