Find Spa Hotels in St. Louis, MO

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Check availability on St. Louis Spa Hotels

Our top choices for St. Louis hotels with a spa

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very good, (1,003 reviews)
  • cleanliness
    Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
The price is £151
includes taxes & fees
28 Apr - 29 Apr
Ameristar Casino Resort and Spa
Massages

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,757 reviews)
  • cleanliness
    Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
The price is £141
includes taxes & fees
19 Apr - 20 Apr
21C Museum Hotel St Louis
Couples treatment room(s), hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,005 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
The price is £407
includes taxes & fees
27 Apr - 28 Apr
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (563 reviews)
  • cleanliness
    Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
The price is £431
includes taxes & fees
3 May - 4 May
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in St. Louis

Pool
Hot tub

Find out more about St. Louis

Top St. Louis (and vicinity) attractions for a relaxing vacation

For travellers seeking an indulgent escape in the greater St. Louis area, the vibrant neighbourhood of Clayton is a splendid choice. This upscale district is home to an array of luxurious spa hotels where guests can unwind after exploring the city's highlights. Just a short drive away, the Missouri Botanical Garden offers a serene retreat with its stunning landscapes and tranquil Japanese Garden, perfect for a leisurely stroll. Art enthusiasts will appreciate a visit to the Saint Louis Art Museum, where world-class exhibits await amidst the picturesque setting of Forest Park, one of the largest urban parks in the United States. Families can enjoy a day of fun at the Saint Louis Zoo, known for its exceptional animal exhibits and free admission, providing a delightful experience for all ages. After a day of adventure, retreat to your spa hotel in Clayton, where attentive service and pampering treatments await, ensuring you feel rejuvenated and cared for. The combination of luxury accommodation and engaging local attractions makes Clayton an ideal base for a memorable family getaway.

Find the best hotels & resorts with spas in St. Louis (and vicinity)

For those seeking a rejuvenating escape in St. Louis, these hotels offer exceptional spa amenities that promise relaxation and pampering during your stay.

The Royal Sonesta Chase Park Plaza St. Louis

  • Why it's great for tailored spa getaway: The Royal Sonesta Chase Park Plaza St. Louis is a sophisticated choice for travellers seeking a relaxing getaway, with a wonderful review rating of 9.0. This hotel features spa treatment rooms, offering guests the chance to unwind with various treatments tailored to their needs.
  • Other amenities: Beyond spa services, guests can enjoy a health club, luxurious designer toiletries, and a poolside bar for refreshing drinks. This hotel also provides valet parking, a concierge service, and the option of self-parking. With nearby golf options and a beautiful balcony in select rooms, it’s an ideal choice for those wanting a mix of relaxation and leisure.
  • Neighborhood: Central West End
  • Nearby attractions: Forest Park - 0 km

21C Museum Hotel St Louis

  • Why it's great for tailored spa getaway: At 21C Museum Hotel St Louis, guests can enjoy a unique blend of art and relaxation, complemented by an excellent review rating of 9.0. The onsite spa features massage treatments and a steam room, ensuring guests can indulge in self-care after exploring the vibrant city.
  • Other amenities: The hotel also offers an indoor pool, accessible fitness centre, and luxurious deep soaking bathtubs in select rooms. Guests can take advantage of valet parking and daily housekeeping, while the chic decor and contemporary art installations throughout the hotel create a vibrant atmosphere that enhances the overall experience.
  • Neighborhood: Downtown West
  • Nearby attractions: City Museum - 0.5 km, Enterprise Center - 0.7 km, St. Louis Union Station - 0.7 km

DoubleTree by Hilton Hotel St. Louis - Chesterfield

  • Why it's great for tailored spa getaway: The DoubleTree by Hilton Hotel St. Louis - Chesterfield is a great option for relaxation seekers, a solid review rating of 8.6. The hotel features treatment rooms where guests can indulge in therapeutic treatments for a refreshing experience.
  • Other amenities: The hotel also offers an indoor pool, hot tub, and access to a health club, ensuring guests can maintain their wellness routines. Additional features include onsite shopping, billiards, and air conditioning for utmost comfort. Guests can also enjoy daily housekeeping, premium bedding, and the convenience of early check-in or late check-out.
  • Nearby attractions: Chesterfield Arts - 1.7 km, The J - Chesterfield Gym & Fitness Center - 2.4 km

Ameristar Casino Resort and Spa

  • Why it's great for tailored spa getaway: Ameristar Casino Resort and Spa is a fantastic destination for spa lovers with a popular review rating of 8.4. The hotel features a full-service spa offering a variety of body treatments and massages, ensuring guests leave feeling refreshed and revitalised.
  • Other amenities: Guests can also enjoy a private hot tub, a large outdoor pool, and convenient 24-hour fitness facilities. The resort includes luxurious suites, a snack bar, and a concierge service, enhancing the overall experience. Additionally, golf nearby and winery tours provide ample opportunities for leisure outside of the spa.
  • Nearby attractions: Historic Main Street - 1.1 km, Ameristar Casino St. Charles - 0 km, Lewis & Clark Boathouse and Nature Center - 1.1 km

Top St. Louis Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"Pool closed and game room closed the website said these amenities would be available 4/1/2026, I would not have booked with this Hotel if the correct information was disclosed on the website when I booked the rooms "
Tracy 3-night trip
Posted 3 hours ago
Clayton Plaza Hotel & Extended Stay

Frequently asked questions

Which hotels in St Louis offer the best spa experiences?
Some of the best spa experiences in St Louis can be found at the Four Seasons Hotel St Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, and 21C Museum Hotel St Louis.

The 5-star Four Seasons Hotel St Louis, with a 9.4 rating, offers an extensive spa experience with a wide array of treatments. Guests can enjoy body wraps, body scrubs, aromatherapy treatments, and various massages, alongside facial treatments and manicures and pedicures. The spa includes a hot tub and steam room, and there are dedicated couples' treatment rooms for shared relaxation.

The 4.5-star Ameristar Casino Resort and Spa, rated 8.4, provides a full-service spa focusing on a diverse treatment menu. This includes aromatherapy treatments, body scrubs, body treatments, and a selection of massages. Hydrotherapy treatments are also available, ensuring a complete wellness circuit.

The 5-star Ritz-Carlton, St. Louis, with a 9.2 rating, provides a serene spa environment with a focus on therapeutic treatments. Guests can choose from deep tissue massages, hot stone massages, body wraps, body scrubs, and aromatherapy treatments, alongside rejuvenating facial treatments.

The 4.5-star 21C Museum Hotel St Louis, with a 9.0 rating, features a spa with a steam room and an indoor pool, providing a tranquil space for relaxation. Massage services are available, and the hotel offers deep soaking bathtubs in rooms for private unwinding.
How much does a spa hotel in St Louis cost?
Enjoy staying in a spa hotel in St Louis, with plenty of hotels from £141 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.
Is it cheaper to book a spa hotel in St Louis with flights as part of a package deal?
Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect holiday package.
Are there hotels in St Louis that offer couples' spa treatments?
For couples seeking spa treatments in St Louis, the Four Seasons Hotel St Louis is an excellent recommendation.

This 5-star hotel, with a 9.4 rating, offers dedicated couples treatment rooms, providing a private and relaxing space for shared spa experiences. Its extensive spa menu includes a variety of body treatments such as wraps and scrubs, along with massages, facials, aromatherapy, and manicures and pedicures. Guests can also enjoy amenities like a hot tub and a steam room.
Which spa hotels in St Louis are near St. Louis, MO (STL-Lambert-St. Louis Intl.)?
For those seeking spa hotels near St. Louis, MO (STL-Lambert-St. Louis Intl.), the Marriott St. Louis Airport is a convenient choice.

This 4-star hotel, with an 8.0 rating, offers massage services, allowing guests to relax and rejuvenate without travelling far from the airport.
Are there any unique spa experiences available in St Louis?
Yes, St. Louis, Missouri offers several unique spa experiences, blending local inspiration with holistic and luxurious approaches.

The Ritz-Carlton, St. Louis features a signature massage experience that incorporates Missouri red granite, inspired by local volcanic rocks, combined with sweet orange to soothe muscles and calm the mind.

Above & Beyond Wellness Spa provides a holistic wellness approach with services such as therapeutic massages, custom facials, hydrotherapy, and innovative non-invasive treatments for muscle strengthening and pelvic health restoration.

Four Seasons Hotel St. Louis Spa offers an After Dark Experience, providing exclusive after-hours use of the spa, including an infrared sauna and private relaxation spaces, alongside luxury treatments with views of the Gateway Arch.

aRa Spa in nearby St. Charles is a large, 7,000-square-foot spa featuring a Swiss shower, hydro-pool, seasonal indoor/outdoor pools, and a state-of-the-art fitness centre.

Aquarius Wellness Centre offers unique spa packages combining signature massages, facials, reflexology, and warm stone massage, often paired with additional treats, and also provides treatments like Himalayan salt stone massage and Reiki healing.
How can I save on a spa hotel in St Louis with Expedia?
Members always get our best prices. Find our best St Louis spa hotel deals by joining One Key™, Expedia's free travel rewards program. As a member, you can unlock instant savings and member perks when you're logged in to your account. For a quick weekend retreat, discover last-minute offers.
Can I cancel my spa hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in St Louis for you.

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