Title: 21C Museum Hotel St Louis Reviews, Deals & Photos 2026 - Expedia.co.uk [See all properties](http://www.expedia.co.uk/Hotel-Search?regionId=3284&destination=St.+Louis%2C+Missouri%2C+United+States+of+America&selected=89164592&adults=2&children=&sort=RECOMMENDED&useRewards=false&semdtl=&userIntent=&vip=false) # 21C Museum Hotel St Louis Contemporary art meets comfort at this downtown St. Louis hotel where travelers can unwind after exploring nearby Busch Stadium and other iconic attractions ## Photo gallery for 21C Museum Hotel St Louis ![Restaurant - 21C Museum Hotel St Louis (St. Louis)](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bd7064dc.jpg?impolicy=resizecrop&rw=598&ra=fit) ![Massages - 21C Museum Hotel St Louis (St. Louis)](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/80c5fbe4.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Bar (on property) - 21C Museum Hotel St Louis (St. Louis)](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/b74ccff9.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Exterior - 21C Museum Hotel St Louis (St. Louis)](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/15dd97ac.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Exterior - 21C Museum Hotel St Louis (St. Louis)](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bedc886c.jpg?impolicy=resizecrop&rw=297&ra=fit) - Overview - Rooms - Location - Policies 21C Museum Hotel St Louis stands in the heart of the city, offering travelers a refined experience with its indoor pool and fitness center. Guests can book a massage at the spa, play billiards at the bar, or start their day with a cooked-to-order breakfast at the coffee shop. ## Reviews 9.0 Wonderful ## Popular amenities - Pet-friendly - Free Wi-Fi - Air-conditioning £116 includes taxes & fees 5 Apr - 6 Apr ## Check prices for these days [Tonight ](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-15&endDate=2026-03-16&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-15&endDate=2026-03-16&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=-1&adults=2) [Tomorrow ](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=-1&adults=2) [This weekend ](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-20&endDate=2026-03-22&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-20&endDate=2026-03-22&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=-1&adults=2) [Next weekend ](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-27&endDate=2026-03-29&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=-1&adults=2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-27&endDate=2026-03-29&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=-1&adults=2) ## Room options All rooms 1 bed 2 beds Showing 10 of 10 rooms ### View all photos for Deluxe Room, 1 King Bed ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/990b5ba3.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Deluxe Room, 1 King Bed 9.0 Wonderful 92 reviews ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Separate bedroom Bathrobes Hairdryer - 309 sq ft - 1 bedroom - Sleeps 2 - 1 King Bed ### View all photos for Luxury Double Room, 2 Queen Beds ![Luxury Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/a28c5617.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Luxury Double Room, 2 Queen Beds 9.4 Exceptional 29 reviews ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Separate bedroom Bathrobes Private bathroom - 423 sq ft - 1 bedroom - Sleeps 4 - 2 Queen Beds ### View all photos for Room (Bunk Bed) ![Room (Bunk Bed) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/7d5056ab.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Room (Bunk Bed) 8.0 Very good 6 reviews ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Bathrobes Hairdryer Private bathroom - 237 sq ft - Sleeps 2 - 1 Single Bunk Bed ### View all photos for Loft, 2 Queen Beds ![Loft, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/639a96f7.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Loft, 2 Queen Beds 8.0 Very good 1 review ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Bathrobes Hairdryer Private bathroom - 431 sq ft - Sleeps 4 - 2 Queen Beds ### View all photos for Deluxe Room, Accessible (Accessible) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/990b5ba3.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Deluxe Room, Accessible (Accessible) ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Bathrobes Hairdryer Private bathroom - 269 sq ft - Sleeps 2 - 1 King Bed ### View all photos for Suite, 1 King Bed (21C) ![Suite, 1 King Bed (21C) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/65fd749e.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Suite, 1 King Bed (21C) ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Separate bath and shower Deep-soaking bath Hairdryer - 1119 sq ft - Sleeps 2 - 1 King Bed ### View all photos for Suite, 1 King Bed (Library) ![Suite, 1 King Bed (Library) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/b3a754e0.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Suite, 1 King Bed (Library) ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Bathrobes Hairdryer Private bathroom - City view - 732 sq ft - Sleeps 2 - 1 King Bed ### View all photos for Luxury Suite, 1 King Bed ![Luxury Suite, 1 King Bed | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/5e154bdf.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Luxury Suite, 1 King Bed 10.0 Exceptional 1 review ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Separate bath and shower Deep-soaking bath Hairdryer - 549 sq ft - Sleeps 2 - 1 King Bed ### View all photos for Deluxe Room, 1 Double Bed, Accessible ![Deluxe Room, 1 Double Bed, Accessible | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/86bd05ab.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Deluxe Room, 1 Double Bed, Accessible ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Bathrobes Hairdryer Private bathroom - 388 sq ft - Sleeps 4 - 1 Double Bed ### View all photos for Deluxe Suite, 1 Double Bed, Accessible ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/990b5ba3.jpg?impolicy=fcrop&w=1200&h=800&quality=medium) ### Deluxe Suite, 1 Double Bed, Accessible ### Highlights Soundproofed Air conditioning Heating Flat-screen TV Blackout curtains Bathrobes Hairdryer Private bathroom - 517 sq ft - Sleeps 2 - 1 Double Bed ## You may also like Ad ![Reception](https://a.travel-assets.com/media/meso_cm/PAPI/Images/lodging/1000000/50000/42200/42122/aadfb5be_b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham Fenton - Pool - Hot tub - Breakfast included - Pet-friendly 8.0 Very good 1,131 reviews £78 includes taxes & fees 16 Mar - 17 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information?chkin=2026-3-16&chkout=2026-3-17&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) Ad ![5 restaurants, breakfast, lunch, dinner served; American cuisine ](https://a.travel-assets.com/media/meso_cm/PAPI/Images/lodging/7000000/6460000/6456500/6456459/0daeb760_b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### River City Casino & Hotel St. Louis - Parking included - Restaurant - Air-conditioning - Gym 9.0 Wonderful 1,493 reviews £87 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information?chkin=2026-3-31&chkout=2026-4-1&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) Ad ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://a.travel-assets.com/media/meso_cm/PAPI/Images/lodging/1000000/50000/40200/40102/c27d1380_b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Wingate by Wyndham St. Louis/Fenton Route 66 Fenton - Pool - Breakfast included - Pet-friendly - Parking included 8.0 Very good 1,156 reviews £69 includes taxes & fees 16 Mar - 17 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Fenton.h40102.Hotel-Information?chkin=2026-3-16&chkout=2026-3-17&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) Ad ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/7000000/6330000/6321800/6321776/c23a522b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Holiday Inn Express & Suites St Louis Airport by IHG Woodson Terrace - Breakfast included - Free airport shuttle - Parking included - Free Wi-Fi 8.6 Excellent 1,001 reviews £110 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Louis-Airport.h6321776.Hotel-Information?chkin=2026-3-29&chkout=2026-3-30&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) Ad ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/16000000/15050000/15041300/15041234/f837c869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Holiday Inn Express Troy by IHG Troy - Pool - Breakfast included - Parking included - Free Wi-Fi 9.4 Exceptional 742 reviews £104 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-Troy.h15041234.Hotel-Information?chkin=2026-4-5&chkout=2026-4-6&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) Ad ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/4ee0764e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Super 8 by Wyndham Troy IL/St. Louis Area Troy - Pool - Breakfast included - Pet-friendly - Parking included 8.0 Very good 1,005 reviews £57 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Super-8-By-Wyndham-Troy-ILSt-Louis-Area.h1090603.Hotel-Information?chkin=2026-3-22&chkout=2026-3-23&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) Ad ![Exterior](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/d38dcff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Holiday Inn Express & Suites Wentzville St Louis West by IHG Wentzville - Pool - Breakfast included - Pet-friendly - Parking included 9.4 Exceptional 877 reviews £125 includes taxes & fees 19 Mar - 20 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-Suites-Wentzville-St-Louis-West.h35848753.Hotel-Information?chkin=2026-3-19&chkout=2026-3-20&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) Ad ![Exterior](https://images.trvl-media.com/lodging/43000000/42200000/42192300/42192228/48a8d8cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Holiday Inn Express & Suites St Peters by IHG St. Peters - Pool - Breakfast included - Parking included - Free Wi-Fi 9.4 Exceptional 396 reviews £101 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Peters.h42192228.Hotel-Information?chkin=2026-3-29&chkout=2026-3-30&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) Ad ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74300/74268/3bf59143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Holiday Inn Express & Suites St. Louis West - Fenton by IHG Fenton - Pool - Breakfast included - Pet-friendly - Free Wi-Fi 8.8 Excellent 1,000 reviews £93 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Louis-West-Fenton.h74268.Hotel-Information?chkin=2026-3-22&chkout=2026-3-23&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) Ad ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/3e0ca2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) #### Holiday Inn Express St. Louis West - O'Fallon by IHG O'Fallon - Pool - Breakfast included - Parking included - Free Wi-Fi 8.6 Excellent 881 reviews £78 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-West-OFallon.h1206489.Hotel-Information?chkin=2026-3-22&chkout=2026-3-23&rm1=a2®ionId=178309&destination=St. Louis (and vicinity)&destType=MARKET&latLong=38.62812,-90.20744&searchId=bb44863b-97da-4dbd-ab36-261a69aed111&top_cur=GBP) ![Mod logo](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Sign in to view eligible discounts and perks. More rewards for more adventures! [Sign in](https://www.expedia.co.uk/login?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSt-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information)[Sign up, it's free](https://www.expedia.co.uk/signup?enable_registration=true&uurl=e3id%3Dredr%26rurl%3D%2FSt-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ## About the area Located in St. Louis, 21C Museum Hotel St Louis is in the city centre. St. Louis Union Station and Gateway Arch are notable landmarks, and the area's natural beauty can be seen at Mississippi River and Forest Park. Check out an event or a game at Enterprise Center, and consider making time for St. Louis Zoo, a top attraction not to be missed. [Visit our St. Louis travel guide](https://www.expedia.co.uk/St-Louis.dx178309) ![Map](https://maps.googleapis.com/maps/api/staticmap?&size=660x330&map_id=3b266eb50d2997c6&zoom=13&markers=icon:https%3A%2F%2Fa.travel-assets.com%2Ftravel-assets-manager%2Feg-maps%2Fproperty.png%7C38.63157%2C-90.20252&channel=expedia-HotelInformation&maptype=roadmap&scale=1&key=AIzaSyCYjQus5kCufOpSj932jFoR_AJiL9yiwOw&signature=q-Y2GipZDMjipVzFokc9jlXBr3o=) 1528 Locust street, St. Louis, MO, 63103 ### What's nearby - ![Washington Avenue Historic District](https://images.trvl-media.com/place/6219551/4ada606a-cc8f-4451-9010-293cace04a6b.jpg?impolicy=resizecrop&rw=115.61&rh=65.03&ra=fit&q=high) Washington Avenue Historic District 2 min walk \- 0.1 miles - ![City Museum as well as a small group of people](https://images.trvl-media.com/place/6069375/57b1a16e-1a67-4ba3-95f8-f81a4136719b.jpg?impolicy=resizecrop&rw=115.61&rh=65.03&ra=fit&q=high) City Museum 5 min walk \- 0.3 miles - ![Union Station, St. Louis, MO](https://images.trvl-media.com/place/502868/8704491b-9324-4c56-89ed-94a638702313.jpg?impolicy=resizecrop&rw=115.61&rh=65.03&ra=fit&q=high) St. Louis Union Station 8 min walk \- 0.4 miles - ![Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.](https://images.trvl-media.com/place/502873/da730472-6151-40a1-b074-013a6c50d0f4.jpg?impolicy=resizecrop&rw=115.61&rh=65.03&ra=fit&q=high) Enterprise Center 8 min walk \- 0.5 miles - St. Louis Aquarium at Union Station 11 min walk \- 0.6 miles ### Getting around - 8th and Pine Station 13 min walk - St. Louis Gateway Station 14 min walk - Lambert-St. Louis International Airport (STL) 24 min drive ### Restaurants - Imo's Pizza Headquarters & Retail Store 7 min walk - Budweiser Kiel Club 6 min walk - Rosalita's Cantina 6 min walk - White Knight Diner 4 min walk - Blood & Sand 2 min walk ## About this property ### 21C Museum Hotel St Louis Luxury hotel near Enterprise Center Located close to St. Louis Union Station and Busch Stadium, 21C Museum Hotel St Louis provides a coffee shop/cafe, dry cleaning/laundry services and a bar. Treat yourself to a massage or other spa services. In addition to a gym and a business centre, guests can connect to free in-room WiFi. You'll also enjoy the following perks during your stay: - An indoor pool - Cooked-to-order breakfast (surcharge), valet parking (surcharge) and a lift - A vending machine, concierge services and a banquet hall - ATM/banking services, a 24-hour front desk and meeting rooms - Guest reviews say great things about the dining options, pool and helpful staff Room features All 104 rooms include comforts such as laptop-friendly workspaces and air conditioning, as well as perks such as free WiFi and desk chairs. Guest reviews highly rate the cleanliness rooms at the property. More amenities include: - Free toiletries and hairdryers - Flat-screen TVs with premium channels - Wardrobes/cupboards, heating and daily housekeeping ### Awards and affiliations Eco-certified property This property participates in Green Key Global – a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy. ## Similar properties ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/c1e52387.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Hyatt Regency St. Louis at The Arch Downtown St. Louis - Pet-friendly - Free Wi-Fi - Restaurant - Air-conditioning 8.4 Very good 3,994 reviews £151 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-23&endDate=2026-03-24&selected=14877&PinnedHotelID=14877&HadPinnedHotel=true®ionId=-1&adults=2) ![Property amenity](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/e43b9580.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Drury Plaza Hotel St. Louis at the Arch Downtown St. Louis - Pool - Hot tub - Breakfast included - Pet-friendly 9.4 Exceptional 3,352 reviews £133 includes taxes & fees 16 Mar - 17 Mar [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17&selected=546271&PinnedHotelID=546271&HadPinnedHotel=true®ionId=-1&adults=2) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/3056142b.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Near Union Station Downtown West - Pool - Hot tub - Breakfast included - Pet-friendly 8.8 Excellent 1,871 reviews £94 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06&selected=26572&PinnedHotelID=26572&HadPinnedHotel=true®ionId=-1&adults=2) ![Indoor pool, a heated pool, open 10:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/5c61cbf8.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Clayton Plaza Hotel & Extended Stay Clayton - Pool - Breakfast included - Pet-friendly - Free Wi-Fi 8.8 Excellent 3,120 reviews £87 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-22&endDate=2026-03-23&selected=18144&PinnedHotelID=18144&HadPinnedHotel=true®ionId=-1&adults=2) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton Grand Center - Pet-friendly - Free Wi-Fi - Restaurant - Air-conditioning 8.8 Excellent 1,053 reviews £116 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-29&endDate=2026-03-30&selected=27616925&PinnedHotelID=27616925&HadPinnedHotel=true®ionId=-1&adults=2) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8800/8738/171d52f3.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### St. Louis Union Station Hotel, Curio Collection by Hilton Downtown West - Pool - Pet-friendly - Free Wi-Fi - Restaurant 8.6 Excellent 1,001 reviews £173 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-22&endDate=2026-03-23&selected=8738&PinnedHotelID=8738&HadPinnedHotel=true®ionId=-1&adults=2) ![Exterior](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/82c4c752.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Live by Loews - St.Louis Downtown St. Louis - Pet-friendly - Free Wi-Fi - Restaurant - Air-conditioning 9.4 Exceptional 1,124 reviews £134 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06&selected=39161277&PinnedHotelID=39161277&HadPinnedHotel=true®ionId=-1&adults=2) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/470000/460400/460354/665259c4.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### The Westin St. Louis Downtown St. Louis - Pet-friendly - Restaurant - Air-conditioning - Breakfast available 8.6 Excellent 1,003 reviews £119 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06&selected=460354&PinnedHotelID=460354&HadPinnedHotel=true®ionId=-1&adults=2) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Union Station Downtown West - Pool - Hot tub - Breakfast included - Pet-friendly 9.4 Exceptional 1,346 reviews £122 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06&selected=37651&PinnedHotelID=37651&HadPinnedHotel=true®ionId=-1&adults=2) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel Downtown St. Louis - Pet-friendly - Free Wi-Fi - Restaurant - Air-conditioning 8.8 Excellent 1,262 reviews £120 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-22&endDate=2026-03-23&selected=8131949&PinnedHotelID=8131949&HadPinnedHotel=true®ionId=-1&adults=2) [Compare similar properties](/Hotel-Search?startDate=2026-03-29&endDate=2026-03-30&selected=89164592&PinnedHotelID=89164592&HadPinnedHotel=true®ionId=-1&adults=2&comparePropertyIds=89164592,14877,546271,26572,18144) ## Property amenities ### Internet - Available in all rooms: Free WiFi - Available in some public areas: Free WiFi ### Parking and transport - Valet parking on site (USD 50 per day; includes in/out privileges) - Limited on-site valet parking ### Food and drink - Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person - A bar/lounge - A coffee shop/cafe - A restaurant ### Things to do - Billiards/pool table - Gym - Indoor pool - Steam room ### Family friendly - Indoor pool - Soundproofed rooms ### Conveniences - 24-hour front desk - ATM - Luggage storage - Vending machine ### Guest services - Change of bedsheets (on request) - Change of towels on request - Concierge services - Dry cleaning/laundry service - Housekeeping (daily) ### Business services - Business centre - Meeting rooms ### Spa - Massage - Spa services ### Accessibility - If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking. - Area rugs in room - Braille/raised signage - Grab bar in shower (89 centimetre high) - Handrails in stairways (91 centimetre high) - Lever door handles - Lift (107 centimetre wide door) - Magnifying mirror - Pool hoist on site - Stair-free path to entrance - Thin carpet in room - Tile flooring in room - Visual fire alarm - Well-lit path to entrance - Wheelchair accessible (may have limitations) - Wheelchair-accessible gym - Wheelchair-accessible lounge - Wheelchair-accessible path of travel - Wheelchair-accessible pool - Wheelchair-accessible public bathroom - Wheelchair-accessible registration desk (91 centimetre high) - Wheelchair-accessible restaurant - Wheelchair-accessible spa - Wheelchairs on site ### More - Banquet hall - Biodegradable coffee stirrers available - Biodegradable drinking straws available - No plastic coffee stirrers - No plastic drinking straws - No plastic soft drink bottles - No plastic water bottles - Reusable cups - Reusable tableware - Smoke-free property ## Room amenities ### Bedroom - Bedsheets provided - Blackout drapes ### Bathroom - Dressing gowns - Free toiletries - Hair dryer - Shampoo - Soap - Toilet paper - Toothbrush and toothpaste (on request) - Towels provided ### Entertainment - Flat-screen TV with premium digital channels ### Food and drink - Espresso maker - Free bottled water - Limited room service ### More - Air conditioning - Desk - Desk chair - Heating - Iron/ironing board - Laptop workspace - Phone - Safe - Soundproofed rooms ## Policies ### Check-in Check-in start time: 4:00 PM; check-in end time: 11:00 AM Late check-in subject to availability Minimum check-in age - 21 ### Check-out Check-out before 11:00 AM ### Special check-in instructions Front desk staff will greet guests on arrival at the property Information provided by the property may be translated using automated translation tools ### Access methods Staffed front desk ### Pets Pets are allowed for an extra charge of USD 100 per accommodation, per stay Service animals are welcome, and are exempt from fees Welcoming dogs only ### Children and extra beds Children are welcome Rollaway/extra beds are not available. Cots (infant beds) are not available ### Payment types at the property ## Important information ### Fees You'll be asked to pay the following charges at the property. Fees may include applicable taxes: - Service fee: USD 5 per accommodation, per stay We have included all charges provided to us by the property. ### Optional extras - Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person - Valet parking fee: USD 50 per day (in/out privileges) - Pet fee: USD 100 per accommodation, per stay - Service animals are exempt from fees The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change. ### You need to know This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. Extra-person charges may apply and vary depending on property policy Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed This property accepts credit cards; cash is not accepted Safety features at this property include a fire extinguisher, a smoke detector and outdoor lighting If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with UK consumer law, property booking services are not subject to the right of withdrawal. ### We should mention Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly) ### Property is also known as 21C Museum Hotel St Louis 21c Museum St Louis St Louis 21C Museum Hotel St Louis Hotel 21C Museum Hotel St Louis St. Louis 21C Museum Hotel St Louis Hotel St. Louis 21C Museum Hotel St Louis (Opening Spring 2023) ## Frequently asked questions ### Does 21C Museum Hotel St Louis have a pool? ### How much does it cost to stay at 21C Museum Hotel St Louis ? ### Is 21C Museum Hotel St Louis pet-friendly? ### How much is parking at 21C Museum Hotel St Louis ? ### What time is check-in at 21C Museum Hotel St Louis ? ### What time is check-out at 21C Museum Hotel St Louis ? ### Where is 21C Museum Hotel St Louis located? ## Have a question? Beta Get instant answers with AI powered search of property information and reviews. Ask a question ## Reviews ## 21C Museum Hotel St Louis Reviews 9.0 ### Wonderful All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.[More information](https://www.expedia.co.uk/lp/b/content-guidelines) ### 9.2 Cleanliness ### 9.2 Amenities ### 9.0 Staff & service ### 9.4 Property conditions & facilities 10 - Excellent 1,188 8 - Good 254 6 - Okay 115 4 - Poor 49 2 - Terrible 60 ## Reviews ### 10/10 Excellent #### Dimitre 18 Jan 2026 Liked: Cleanliness, amenities, property conditions & facilities Great hotel! Art, food and drinks were fantastic ##### Dimitre Stayed 1 night in Jan 2026 ### 10/10 Excellent #### Diana 8 Feb 2026 Liked: Cleanliness, property conditions & facilities Room was clean stuff was friendly and everyone was super nice ##### Diana Stayed 2 nights in Feb 2026 ### 10/10 Excellent #### Juanita 18 Jan 2026 Liked: Cleanliness, amenities, property conditions & facilities The rooms were nice and clean. Staff was friendly. ##### Juanita Stayed 1 night in Jan 2026 ### 8/10 Good #### Mikel 18 Jan 2026 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Great Location, great atmosphere. Drinks and food on the floor level, beautiful artwork is on display. ##### Mikel Stayed 1 night in Jan 2026 ### 10/10 Excellent #### Jennifer 18 Jan 2026 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Cool hotel to stay at near enterprise center. Had fun with the penguins and liked the activities in the hotel (museum, pool table, shuffleboard) ##### Jennifer Stayed 1 night in Jan 2026 ### 10/10 Excellent #### Meredith 3 Feb 2026 Liked: Cleanliness, amenities, property conditions & facilities Hotel was very quiet and staff helpful and courteous. The coffee shop was great for coffee and breakfast and the rooms were clean with hot water and great water pressure. The only thing I would change was the mattress - bed was very firm, kind of felt like lying on a table. Gallery was a fun feature and next time I'm in STL I will be back! ##### Meredith Stayed 1 night in Jan 2026 ### 10/10 Excellent #### Sharon 16 Dec 2025 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Hotel was comfortable, clean and unique. All staff was wonderful ##### Sharon Stayed 3 nights in Dec 2025 ### 10/10 Excellent #### London 7 Dec 2025 Liked: Cleanliness, amenities, property conditions & facilities Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. ##### London Stayed 1 night in Nov 2025 ### 10/10 Excellent #### Hannah 10 Nov 2025 Liked: Staff & service, amenities Disliked: Cleanliness Great room, good staff and amenities. ##### Hannah Stayed 1 night in Nov 2025 ### 10/10 Excellent #### Theresa 10 Nov 2025 Liked: Cleanliness, staff & service, amenities Clean, quiet and the staff was great! ##### Theresa Stayed 2 nights in Nov 2025 ### 10/10 Excellent #### Jemma 3 Nov 2025 Liked: Cleanliness, staff & service, property conditions & facilities, room comfort The food was great, the room was clean and the staff were so nice and accommodating ##### Jemma Stayed 1 night in Oct 2025 ### 10/10 Excellent #### Barbara 7 Dec 2025 Liked: Cleanliness, amenities, property conditions & facilities The room was spotless and the details were beautiful. The hotel was a really fun experience! ##### Barbara Stayed 1 night in Oct 2025 ### 10/10 Excellent #### Cory 7 Dec 2025 Liked: Cleanliness, amenities, property conditions & facilities Very clean nice place. Staff was very nice and helpful ##### Cory Stayed 2 nights in Dec 2025 ### 10/10 Excellent #### Chris 17 Nov 2025 Liked: Cleanliness, amenities, property conditions & facilities Great staff and clean room ##### Chris Stayed 2 nights in Nov 2025 ### 10/10 Excellent #### Aisha 3 Jan 2026 Liked: Cleanliness, amenities, property conditions & facilities I really enjoyed my stay. My room was clean and the amenities were amazing. The gym was modern and up to date. The pool and hot tub were perfect and I even took a moment to get in the sauna. I haven't been that relaxed in a long time. ##### Aisha Stayed 2 nights in Dec 2025 ### 10/10 Excellent #### Douglas 22 Dec 2025 Liked: Cleanliness, amenities, property conditions & facilities The entire hotel was fantastic. Beautifully decorated, so much to see. The art gallery was fantastic, the servers at the bar were friendly and phenomenal and just made for a great evening. The food was fantastic. Every inch of the building was well styled and the room was fantastic. Can’t wait to go back! Highly recommend. ##### Douglas Stayed 1 night in Dec 2025 ### 10/10 Excellent #### Christopher 16 Nov 2025 Liked: Cleanliness, staff & service, amenities Beautiful venue; comfortable room; clean; good location. ##### Christopher Stayed 2 nights in Nov 2025 ### 10/10 Excellent #### Jenifer 2 Dec 2025 Liked: Cleanliness, amenities, property conditions & facilities Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area. ##### Jenifer Stayed 1 night in Nov 2025 ### 10/10 Excellent #### Frank 30 Nov 2025 Liked: Cleanliness, amenities, property conditions & facilities Awesome hotel. One of the best I've stayed in. However, they need a good chef in both the bar/restaurant and the cafe. Other than the food, it was great. ##### Frank Stayed 3 nights in Nov 2025 ### 10/10 Excellent #### Sheyanne 9 Nov 2025 Liked: Cleanliness, property conditions & facilities Staff was amazing ##### Sheyanne Stayed 1 night in Oct 2025 ### 10/10 Excellent #### Kristin 14 Nov 2025 Liked: Cleanliness, amenities, property conditions & facilities Clean rooms, amazing art and unique everything! ##### Kristin Stayed 1 night in Nov 2025 ### 10/10 Excellent #### Benjamin 30 Aug 2025 Liked: Cleanliness, staff & service, amenities, property conditions & facilities Amazing pool, great food and drink options, terrific staff. ##### Benjamin Stayed 1 night in Aug 2025 ### 10/10 Excellent #### Laura 29 Nov 2025 Liked: Cleanliness, staff & service, amenities Clean room. Yummy dinner. Beautiful artwork. ##### Laura Stayed 1 night in Nov 2025 ### 8/10 Good #### Julie 13 Jan 2026 Liked: Cleanliness, amenities, property conditions & facilities This hotel is so unique and everyone was so nice! Loved my room (Room 709) however on 2 dates (January 6 and 10), my room was not serviced at all. My towels were still in a pile on the floor when I came back at night. I still had extras so it was okay, but just surprised me. I loved all of the amenities and the bed was very comfortable. Idol Wolf was incredible! Food was so delicious!! Loved going to Good Press in the morning too! The Black Walnut Latte was so good! ##### Julie Stayed 7 nights in Jan 2026 ### 10/10 Excellent #### Megan 12 Nov 2025 Liked: Cleanliness, property conditions & facilities, room comfort Incredible lofted ceilings - detailed and thoughtful way to engage with a relaxing and business experience. ##### Megan Stayed 3 nights in Nov 2025 ### Expedia's Latest Trends ### Hotels > - [Private Indoor Pool & Basketball Court Retreat with Arcade Games, Sleeps 50, Free Tickets & Views](https://www.expedia.co.uk/Branson-Hotels-12-Bdrm-Lake-Home-Private-Indoor-Pool-Basketball-Court-Staycation.h41914917.Hotel-Information) > - [Aparthotels Portsmouth](https://www.expedia.co.uk/Portsmouth-Apart-Hotels.d6057414-aaApartHotels.Travel-Guide-Accommodation) > - [Clayton Plaza Hotel & Extended Stay](https://www.expedia.co.uk/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) > - [Hilton Pennywell St. Louis at the Arch](https://www.expedia.co.uk/St-Louis-Hotels-Hilton-St-Louis-Downtown-At-The-Arch.h1152198.Hotel-Information) > - [Hotels in Hayes](https://www.expedia.co.uk/Hayes-Hotels.d10517.Travel-Guide-Hotels) > - [The West End Hotel King bed by Cortex, Forest Park & BJC](https://www.expedia.co.uk/St-Louis-Hotels-The-West-End-King-Bed-By-Cortex.h107221350.Hotel-Information) > - [Elegant 2700 Sq Ft True Log Cabin-Private Hot Tub-Game Room-Pool Table-Best View Near Big Cedar](https://www.expedia.co.uk/Branson-Hotels-Luxury-2700-Sq-Ft-Log-Cabin-W-Private-Hot-Tub-Game-Room-Pool-Table-Best-View.h33681549.Hotel-Information) > - [5 Star Hotels in Tenby](https://www.expedia.co.uk/5Star-Tenby-Hotels.s50-0-d182887.Travel-Guide-Filter-Hotels) > - [Hotel Saint Louis, Autograph Collection](https://www.expedia.co.uk/St-Louis-Hotels-Hotel-Saint-Louis.h27478599.Hotel-Information) > - [Pet-Friendly Hotels in Crawley](https://www.expedia.co.uk/Crawley-Hotels-Pet-Friendly-Hotel.0-0-d4612-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) > - [Hilton Promenade at Branson Landing](https://www.expedia.co.uk/Branson-Hotels-Hilton-Promenade-At-Branson-Landing.h1497923.Hotel-Information) > - [Hotels near Cave Hill Country Park](https://www.expedia.co.uk/Cave-Hill-Country-Park-Hotels.0-l6083457-0.Travel-Guide-Filter-Hotels) > - [Hyatt Vacation Club at The Lodges at Timber Ridge, Branson](https://www.expedia.co.uk/Branson-Hotels-Lodges-At-Timber-Ridge-By-Welk-Resorts.h2370647.Hotel-Information) > - [Best Western Coach House](https://www.expedia.co.uk/Springfield-Hotels-Best-Western-Plus-Coach-House.h6441.Hotel-Information) > - [Wander Inn](https://www.expedia.co.uk/Branson-Hotels-Dockers-Inn.h856254.Hotel-Information) > - [Hotels in Kingsbury](https://www.expedia.co.uk/Kingsbury-Hotels.d6232870.Travel-Guide-Hotels) > - [The Ritz-Carlton, St. Louis](https://www.expedia.co.uk/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information) ### Flights > - [Flights from Tremblay-en-France (CDG) to Faaa (PPT)](https://www.expedia.co.uk/lp/flights/cdg/ppt/paris-to-papeete) > - [Flights from Doncaster (DSA) to Málaga (AGP)](https://www.expedia.co.uk/lp/flights/dsa/agp/doncaster-to-malaga) > - [Flights from London (LON-All Airports) to Medellín (MDE-José María Córdova Intl.)](https://www.expedia.co.uk/lp/flights/lon/mde/london-to-medellin) ### Cars ### Packages > - [Avondale Flea Market](https://www.expedia.co.uk/Avondale-Flea-Market-Harare.d553248635998020060.Attraction) > - [Iceland](https://www.expedia.co.uk/lp/theme-holidays/romantic-holidays/79/Iceland) > - [Villamartin Holidays](https://www.expedia.co.uk/Villamartin.d6048180.Holidays-City-Breaks) ### General > - [Visit Darragh Cross](https://www.expedia.co.uk/Darragh-Cross.dx553248635939575620) ---