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Visitors to this part of Northeast Missouri will be rubbing shoulders with approximately 320,000 local residents.
You'll find this destination some 110 miles from Jefferson City, the state capital of Missouri. It's also roughly 20 miles from Smithton.
The Gateway Arch is of course, a world-famous attraction.
Give the kids a break from sightseeing and enjoy some quality time together at Grants Farm and Six Flags St. Louis. The Magic House - St. Louis Children's Museum and Alligator Creek Aquatic Center are also worth visiting if the little ones aren't too worn out.
St. Louis Children's Aquarium will teach your kids about the significance of marine life conservation.
You and your kids will have a blast seeing the rare and exotic animals at the St. Louis Zoo. Be sure to ask the staff about hands-on activities and where to find the zoo's most popular inhabitants.
Spend the afternoon with beer freaks from all around the world at the Anheuser-Busch Brewery, a renowned institution here. Take a close look at the equipment to find out what makes the beer here so tasty.
Delight in a great day out with your buddies at the Chandler Hill Vineyards, the Yellow Farmhouse Winery or the Sugar Creek Winery. Meet the cellar masters, try out the latest vintage and then buy a few bottles for the road.
Whether you want to put on your poker face or just get a taste of the lively sights and sounds, the Hollywood Casino and the Ameristar Casino St. Charles are not to be missed. If you need more high-stakes thrills, why not head onwards to the Lumiere Place Casino and the River City Casino?
Botanical displays impressive trees and sinuous garden paths await green thumbs at the Missouri Botanical Gardens and Arboretum and the Sophia M. Sachs Butterfly House.
For fresh air and relaxation, grab something for lunch and find a shady nook at one of the area's pleasant urban parks, such as Laumeier Sculpture Park and O'Fallon Park. Jefferson National Expansion Memorial Park and Citygarden are two more excellent places to while away the day and catch up on some reading.
Get in the know about St. Louis by collecting some pamphlets and chatting to the workers at Weldon Spring Site Interpretive Center and Dennis and Judith Jones Visitor and Education Center.
Switch your phone to silent and give yourself a break from the stresses of the modern world at August A. Busch Memorial Conservation Area and Lone Elk Park. Babler State Park and Route 66 State Park are also popular among nature lovers.
Broaden your perspectives with a trip to one of the area's wonderfully curated cultural spaces. The City Museum and the Museum of Transportation offer a range of displays and collections that are bound to keep you captivated. Another two to consider are the St. Louis Car Museum and the Historic Aircraft Restoration Museum.
See intriguing artifacts and learn about scientific breakthroughs at the St. Louis Science Center.
Add to your appreciation of the artistic process, and perhaps even find something to take back home at one of the various gallery spaces. Start off your tour of this creative paradise by stopping in at the St. Louis Art Museum and the Pulitzer Foundation for the Arts. The Componere Gallery and the Contemporary Art Museum St. Louis are also well worth your time if you can squeeze them in.
Even if you were never a history nerd, you can still enjoy reflecting on the past at the Missouri History Museum and the Arnold Historical Society & Museum.
Discover the region's past with a trip to the 9-11 Memorial or the Lindenwood University, just two of the preserved historic sites here. More tales from a bygone era await at the Faust Park and Old Courthouse.
Eads Bridge and Old Chain of Rocks Bridge are impressive historic structures that will survive well into the future.
Whether you think of yourself as spiritual or not, you're sure to enjoy a trip to Cathedral Basilica of St. Louis and Shrine of St. Joseph. If you'd be interested to look at a couple more religious sites, have a walk about Old Cathedral of St. Louis of France and St. Alphonsus Liguori Catholic Church.
Once you've ticked off all the major points of interest in and around St. Louis, take the time to visit a couple of its lesser-known sights. Westport Plaza and the Central Public Library could be up your alley. Also, think about seeing the Center of Creative Arts and the St. Louis Walk of Fame if you have the time.
This 18-story Hyatt Regency hotel is 4 blocks from Busch Stadium and within a mile of Edward Jones Dome, Scottrade Center, Laclede's Landing, and the America's Center.
Situated near the airport, this hotel is 1.4 mi (2.3 km) from Hollywood Casino Amphitheatre and within 9 mi (15 km) of Lindenwood University and Family Arena. Gateway Arch and Scottrade Center are also within 25 mi (40 km).
Situated in Fenton, this motel is 1.3 mi (2.1 km) from LIFECHURCH and within 6 mi (10 km) of Laumeier Sculpture Park and Powder Valley Conservation Nature Center. Magic House - St. Louis Children's Museum and Frank Lloyd Wright House in Ebsworth Park are also within 6 mi (10 km).
This downtown St. Louis hotel connects to Lumiere Place Casino; Laclede's Landing and the Edward Jones Dome are 3 blocks away.
Situated in Washington Park, this motel is within 6 mi (10 km) of Katherine Dunham Museum, Dome at America’s Center, and Cahokia Mounds State Historic Site. Gateway International Raceway and Malcolm Martin Memorial Park are also within 6 mi (10 km).
This historic 13-story St. Louis hotel is 1 block from Scottrade/Peabody Opera House Complex, 3 blocks from Union Station, and 5 blocks from Busch Stadium. The Gateway Arch is 1 mile away.
Situated in the business district, this hotel is within 9 mi (15 km) of St. Louis Car Museum, Hollywood Casino Amphitheatre, and Sophia M. Sachs Butterfly House. St. Louis Zoo and Six Flags St. Louis are also within 32 mi (52 km).
Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse and Busch Stadium. Gateway Arch and Dome at America’s Center are also within 15 minutes.