£444 Cheap Flights from Manchester (MAN) to St. Louis (STL)

View £444 flight on Tue, 29 Dec 2026Opens in a new window

Popular airlines from Manchester Airport (MAN) to Lambert-St. Louis International Airport (STL)

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Cheap Flights from Manchester (MAN) to St. Louis (STL)

Prices were available within the past 7 days and start at £444 for one-way flights and £692 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Tue, 15 Sept - Wed, 23 Sept
MAN
Manchester
STL
St. Louis
£692 Return, found 7 hours ago
£692
Return
found 7 hours ago
Select British Airways flight, departing Tue, 15 Sept from Manchester to St. Louis, returning Wed, 23 Sept, priced at £692 found 7 hours ago
British Airways
Wed, 28 Oct - Sun, 8 Nov
MAN
Manchester
STL
St. Louis
£693 Return, found 1 day ago
£693
Return
found 1 day ago
Select British Airways flight, departing Wed, 28 Oct from Manchester to St. Louis, returning Sun, 8 Nov, priced at £693 found 1 day ago
British Airways
Tue, 8 Sept - Wed, 16 Sept
MAN
Manchester
STL
St. Louis
£695 Return, found 7 hours ago
£695
Return
found 7 hours ago
Select British Airways flight, departing Tue, 8 Sept from Manchester to St. Louis, returning Wed, 16 Sept, priced at £695 found 7 hours ago
British Airways
Tue, 15 Sept - Wed, 23 Sept
MAN
Manchester
STL
St. Louis
£695 Return, found 7 hours ago
£695
Return
found 7 hours ago
Select British Airways flight, departing Tue, 15 Sept from Manchester to St. Louis, returning Wed, 23 Sept, priced at £695 found 7 hours ago
American Airlines
Tue, 8 Sept - Wed, 16 Sept
MAN
Manchester
STL
St. Louis
£697 Return, found 7 hours ago
£697
Return
found 7 hours ago
Select American Airlines flight, departing Tue, 8 Sept from Manchester to St. Louis, returning Wed, 16 Sept, priced at £697 found 7 hours ago
American Airlines
Wed, 28 Oct - Sun, 8 Nov
MAN
Manchester
STL
St. Louis
£698 Return, found 1 day ago
£698
Return
found 1 day ago
Select American Airlines flight, departing Wed, 28 Oct from Manchester to St. Louis, returning Sun, 8 Nov, priced at £698 found 1 day ago
American Airlines
Wed, 28 Oct - Sun, 8 Nov
MAN
Manchester
STL
St. Louis
£699 Return, found 1 day ago
£699
Return
found 1 day ago
Select American Airlines flight, departing Wed, 28 Oct from Manchester to St. Louis, returning Sun, 8 Nov, priced at £699 found 1 day ago
KLM
Tue, 3 Nov - Tue, 10 Nov
MAN
Manchester
STL
St. Louis
£721 Return, found 6 days ago
£721
Return
found 6 days ago
Select KLM flight, departing Tue, 3 Nov from Manchester to St. Louis, returning Tue, 10 Nov, priced at £721 found 6 days ago
Air France
Tue, 3 Nov - Tue, 10 Nov
MAN
Manchester
STL
St. Louis
£721 Return, found 6 days ago
£721
Return
found 6 days ago
Select Air France flight, departing Tue, 3 Nov from Manchester to St. Louis, returning Tue, 10 Nov, priced at £721 found 6 days ago
Virgin Atlantic
Wed, 11 Nov - Mon, 16 Nov
MAN
Manchester
STL
St. Louis
£724 Return, found 1 day ago
£724
Return
found 1 day ago
Select Virgin Atlantic flight, departing Wed, 11 Nov from Manchester to St. Louis, returning Mon, 16 Nov, priced at £724 found 1 day ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city centre is 20 minutes. Flights from £963
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city centre20 min
Flights from £963

Frequently asked questions

How much does a flight from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
One-way flights typically cost between £724 and £4,089 and return flights often range between £724 and £4,089. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
How do I find cheap flights from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
There are approximately 41 connecting flights per day from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.). Some common connection points include (DUB), Heathrow (LHR), and Schiphol (AMS).
What is the earliest flight from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The earliest flight from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) (STL) typically departs at approximately 5:35 AM local time, operated by KLM and Delta. This is a seasonal service active in June. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
You'll typically find the most flights from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) on a Tuesday, with around 44 flights available. This gives you a good selection of options for your journey. Major airlines on this route include British Airways, KLM, and Lufthansa. Flight schedules are consistent throughout the week.
What are the most popular departure times for flights from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The most popular departure times for flights from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) (STL) are in the early morning, from 6am to 9am. About 38% of passengers prefer this time. Many major carriers, including British Airways, American Airlines and Lufthansa, offer flights during this window. This timing works well because it allows you to start your journey early and arrive at your destination with plenty of time left in the day.
How long does it take to fly from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Flights from MAN to STL with one stop typically take around 13 hours 20 minutes, covering approximately 4,065 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Select the "Business class" and "First class" filters when looking for MAN to STL flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?
It's easy to earn miles on a Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for St. Louis from MAN (MAN)?
From MAN (MAN), you can fly into Lambert-St. Louis Intl. (STL) to reach St. Louis. Some flights may connect through major hubs like Heathrow (LHR), Frankfurt Intl. (FRA), Schiphol (AMS) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?
Typically, booking a last minute flight from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?
Securing a Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your Manchester (MAN) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Manchester
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, British Airways, Brussels Airlines, Delta, Finnair, Iberia, KLM, Lufthansa, Scandinavian Airlines, Turkish Airlines, United, Virgin Atlantic
Return price
£691
Distance
6502 km

Book with confidence

Compare flights from Manchester to St. Louis easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Manchester to St. Louis. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Lambert-St. Louis Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Manchester to Lambert-St. Louis Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Manchester (MAN) to Lambert-St. Louis Intl. (STL)

The easiest way to view the best deals on flights from Manchester to St. Louis today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Manchester to Lambert-St. Louis Intl. start at just £692 and range up to £724.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Manchester and St. Louis
  • booking your flight during September, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Manchester to St. Louis flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Manchester to Lambert-St. Louis Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Manchester to St. Louis easily and book with confidence

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*Available to Expedia members.