Gateway Arch in St. Louis Missouri, America, USA.

£141 Cheap Flights from San Francisco (SFO) to St. Louis (STL)

View £141 flight on Wed, 8 Jul 2026Opens in a new window

Popular airlines from San Francisco International Airport (SFO) to Lambert-St. Louis International Airport (STL)

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Cheap Flights from San Francisco (SFO) to St. Louis (STL)

Prices were available within the past 7 days and start at £141 for one-way flights and £359 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Alaska Airlines
Wed, 22 Jul - Tue, 28 Jul
SFO
San Francisco
STL
St. Louis
£359 Return, found 2 days ago
£359
Return
found 2 days ago
Select Alaska Airlines flight, departing Wed, 22 Jul from San Francisco to St. Louis, returning Tue, 28 Jul, priced at £359 found 2 days ago
Alaska Airlines
Fri, 10 Jul - Tue, 14 Jul
SFO
San Francisco
STL
St. Louis
£359 Return, found 2 days ago
£359
Return
found 2 days ago
Select Alaska Airlines flight, departing Fri, 10 Jul from San Francisco to St. Louis, returning Tue, 14 Jul, priced at £359 found 2 days ago
Alaska Airlines
Fri, 10 Jul - Tue, 14 Jul
SFO
San Francisco
STL
St. Louis
£361 Return, found 2 days ago
£361
Return
found 2 days ago
Select Alaska Airlines flight, departing Fri, 10 Jul from San Francisco to St. Louis, returning Tue, 14 Jul, priced at £361 found 2 days ago
Alaska Airlines
Thu, 6 Aug - Wed, 12 Aug
SFO
San Francisco
STL
St. Louis
£370 Return, found 5 days ago
£370
Return
found 5 days ago
Select Alaska Airlines flight, departing Thu, 6 Aug from San Francisco to St. Louis, returning Wed, 12 Aug, priced at £370 found 5 days ago
Alaska Airlines
Thu, 24 Sept - Sun, 27 Sept
SFO
San Francisco
STL
St. Louis
£374 Return, found 5 days ago
£374
Return
found 5 days ago
Select Alaska Airlines flight, departing Thu, 24 Sept from San Francisco to St. Louis, returning Sun, 27 Sept, priced at £374 found 5 days ago
Alaska Airlines
Fri, 28 Aug - Tue, 1 Sept
SFO
San Francisco
STL
St. Louis
£386 Return, found 6 days ago
£386
Return
found 6 days ago
Select Alaska Airlines flight, departing Fri, 28 Aug from San Francisco to St. Louis, returning Tue, 1 Sept, priced at £386 found 6 days ago
Delta
Fri, 9 Oct - Mon, 12 Oct
SFO
San Francisco
STL
St. Louis
£391 Return, just found
£391
Return
just found
Select Delta flight, departing Fri, 9 Oct from San Francisco to St. Louis, returning Mon, 12 Oct, priced at £391 just found
Alaska Airlines
Thu, 6 Aug - Wed, 12 Aug
SFO
San Francisco
STL
St. Louis
£398 Return, found 5 days ago
£398
Return
found 5 days ago
Select Alaska Airlines flight, departing Thu, 6 Aug from San Francisco to St. Louis, returning Wed, 12 Aug, priced at £398 found 5 days ago
United
Fri, 9 Oct - Mon, 12 Oct
SFO
San Francisco
STL
St. Louis
£421 Return, just found
£421
Return
just found
Select United flight, departing Fri, 9 Oct from San Francisco to St. Louis, returning Mon, 12 Oct, priced at £421 just found
American Airlines
Fri, 9 Oct - Mon, 12 Oct
SFO
San Francisco
STL
St. Louis
£645 Return, just found
£645
Return
just found
Select American Airlines flight, departing Fri, 9 Oct from San Francisco to St. Louis, returning Mon, 12 Oct, priced at £645 just found

Frequently asked questions

How much does a flight from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
One-way flights typically cost between $447 and $1,571 and return flights often range between $447 and $1,571. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
September is typically the cheapest month to fly from San Francisco International Airport (SFO) to Lambert-St. Louis International Airport (STL), with average round-trip fares around 886 CAD. This is about 18% lower than the average price throughout the year. September often sees lower prices as the summer travel rush ends and before the holiday season begins, leading to reduced demand. April and October are also good months to find deals on this route.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Enter SFO to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best airline to fly with from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will differ from traveler to traveler. If you like to fly early, UA offers early morning flights. If price is the most important factor, WN typically offers the lowest fares. WN offers the most daily flights from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Based on booking data from the past year, the cheapest months to fly from San Francisco International Airport (SFO) to Lambert-St. Louis International Airport (STL) are typically September and October, with average round-trip flights around 886 CAD. While these months offer great value, the most popular times to travel are April and July, meaning you'll find plenty of flight options during those periods. If you're looking for the best balance of price and availability, consider booking during the shoulder seasons around these popular times.*Prices based on flights available on Expedia in the last year.
How many flights per day from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
When flying from San Francisco International (SFO) to Lambert-St. Louis International (STL), you'll find approximately 2 nonstop flights per day. For even more choice, look at flights that include layovers, as there are around 150 connecting flights daily. Some common connection points include O'Hare Intl. (ORD), Los Angeles Intl. (LAX), and Seattle - Tacoma Intl. (SEA).
What is the earliest flight from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The earliest flight from San Francisco International Airport (SFO) to Lambert-St. Louis International Airport (STL) typically departs at approximately 12:05 AM local time, operated by Delta. This is a seasonal service active in May. An early departure like this can help maximize your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
You'll find the most flights from San Francisco Intl. (SFO) to Lambert-St. Louis Intl. (STL) on a Monday, with around 93 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Alaska Airlines, United Airlines, and Southwest Airlines.
What are the most popular departure times for flights from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The most popular departure times for flights from San Francisco International Airport (SFO) to Lambert-St. Louis International Airport (STL) are in the early morning, from 6am to 9am. About 21% of passengers prefer this time. Many major carriers, including American Airlines, United Airlines and Southwest Airlines, offer flights during this window. This timing works well for travelers who want to arrive in St. Louis early in the day, giving you more time to settle in or start your activities.
How long does it take to fly from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Flying nonstop from SFO to STL takes around 4 hours, with the route covering approximately 1,732 miles. Flights with a layover typically take 3 hours 20 minutes longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Select the "Business class" and "First class" filters when looking for SFO to STL flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?
It's easy to earn miles on a San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for St. Louis from San Francisco Intl. (SFO)?
If you're planning to travel to St. Louis from San Francisco Intl. (SFO), you can fly into Lambert-St. Louis Intl. (STL) Some flights may connect through major hubs like Harry Reid Intl. (LAS), Los Angeles Intl. (LAX), San Diego Intl. (SAN) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?
Typically, booking a last minute flight from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?
Securing a San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your San Francisco, CA (SFO-San Francisco Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
San Francisco Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Alaska Airlines
Return price
£358
Distance
2771 km
Average flight time
6 hours 43 mins

Book with confidence

Compare flights from San Francisco to St. Louis easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from San Francisco to St. Louis. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Lambert-St. Louis Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from San Francisco Intl. to Lambert-St. Louis Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from San Francisco Intl. (SFO) to Lambert-St. Louis Intl. (STL)

The easiest way to view the best deals on flights from San Francisco to St. Louis today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from San Francisco Intl. to Lambert-St. Louis Intl. start at just £359 and range up to £645.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near San Francisco and St. Louis
  • booking your flight during July, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your San Francisco to St. Louis flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from San Francisco Intl. to Lambert-St. Louis Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from San Francisco to St. Louis easily and book with confidence

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*Available to Expedia members.