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£302 Cheap Flights from Columbus (CMH) to St. Louis (STL)

View £302 flight on Wed, 16 Sept 2026Opens in a new window

Popular airlines from Port Columbus International Airport (CMH) to Lambert-St. Louis International Airport (STL)

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Cheap Flights from Columbus (CMH) to St. Louis (STL)

Prices were available within the past 7 days and start at £302 for one-way flights and £657 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Alaska Airlines
Thu, 20 Aug - Mon, 24 Aug
CMH
Columbus
STL
St. Louis
£657 Return, found 3 days ago
£657
Return
found 3 days ago
Select Alaska Airlines flight, departing Thu, 20 Aug from Columbus to St. Louis, returning Mon, 24 Aug, priced at £657 found 3 days ago
Alaska Airlines
Thu, 20 Aug - Mon, 24 Aug
CMH
Columbus
STL
St. Louis
£775 Return, found 3 days ago
£775
Return
found 3 days ago
Select Alaska Airlines flight, departing Thu, 20 Aug from Columbus to St. Louis, returning Mon, 24 Aug, priced at £775 found 3 days ago
Alaska Airlines
Mon, 14 Sept - Mon, 21 Sept
CMH
Columbus
STL
St. Louis
£783 Return, found 2 days ago
£783
Return
found 2 days ago
Select Alaska Airlines flight, departing Mon, 14 Sept from Columbus to St. Louis, returning Mon, 21 Sept, priced at £783 found 2 days ago
Alaska Airlines
Thu, 20 Aug - Mon, 24 Aug
CMH
Columbus
STL
St. Louis
£792 Return, found 3 days ago
£792
Return
found 3 days ago
Select Alaska Airlines flight, departing Thu, 20 Aug from Columbus to St. Louis, returning Mon, 24 Aug, priced at £792 found 3 days ago
Alaska Airlines
Mon, 14 Sept - Mon, 21 Sept
CMH
Columbus
STL
St. Louis
£896 Return, found 2 days ago
£896
Return
found 2 days ago
Select Alaska Airlines flight, departing Mon, 14 Sept from Columbus to St. Louis, returning Mon, 21 Sept, priced at £896 found 2 days ago
Alaska Airlines
Thu, 20 Aug - Mon, 24 Aug
CMH
Columbus
STL
St. Louis
£898 Return, found 3 days ago
£898
Return
found 3 days ago
Select Alaska Airlines flight, departing Thu, 20 Aug from Columbus to St. Louis, returning Mon, 24 Aug, priced at £898 found 3 days ago
Alaska Airlines
Thu, 20 Aug - Mon, 24 Aug
CMH
Columbus
STL
St. Louis
£903 Return, found 3 days ago
£903
Return
found 3 days ago
Select Alaska Airlines flight, departing Thu, 20 Aug from Columbus to St. Louis, returning Mon, 24 Aug, priced at £903 found 3 days ago
Alaska Airlines
Mon, 14 Sept - Mon, 21 Sept
CMH
Columbus
STL
St. Louis
£919 Return, found 2 days ago
£919
Return
found 2 days ago
Select Alaska Airlines flight, departing Mon, 14 Sept from Columbus to St. Louis, returning Mon, 21 Sept, priced at £919 found 2 days ago
Alaska Airlines
Thu, 20 Aug - Mon, 24 Aug
CMH
Columbus
STL
St. Louis
£966 Return, found 3 days ago
£966
Return
found 3 days ago
Select Alaska Airlines flight, departing Thu, 20 Aug from Columbus to St. Louis, returning Mon, 24 Aug, priced at £966 found 3 days ago
Alaska Airlines
Thu, 20 Aug - Mon, 24 Aug
CMH
Columbus
STL
St. Louis
£970 Return, found 3 days ago
£970
Return
found 3 days ago
Select Alaska Airlines flight, departing Thu, 20 Aug from Columbus to St. Louis, returning Mon, 24 Aug, priced at £970 found 3 days ago

Frequently asked questions

How much does a flight from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
You can find one-way and return flights from CMH to STL with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when CMH to STL ticket fares go up or down.
What is the cheapest month to fly from Columbus, OH (CMH) to St. Louis, MO (STL)?
The cheapest months to fly from Columbus, OH (CMH) to St. Louis, MO (STL) are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Columbus, OH (CMH) to St. Louis, MO (STL)?
Enter CMH to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Thurgood Marshall (BWI), starting from around £138. Louis Intl.), with tickets starting from around £152 for flights that can be booked for departure within the next year. Southwest Airlines is one of the cheapest airlines offering nonstop return flights from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Southwest Airlines also offers one of the cheapest connecting return flights on this route, with a layover in Baltimore Washington Intl. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best airline to fly with from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will differ from traveler to traveler. If you like to fly early, Southwest Airlines offers early morning flights. If price is the most important factor, Southwest Airlines typically offers the lowest fares. Southwest Airlines offers the most daily flights from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Columbus, OH (CMH) to St. Louis, MO (STL)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
You'll find around 2 nonstop flights per day from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.). For even more choices, look at flights that include layovers, as there are approximately 89 connecting flights per day. Some common connection points include O'Hare Intl. (ORD), Hartsfield-Jackson Atlanta Intl. (ATL), and Midway Intl. (MDW).
What is the earliest flight from Columbus, OH (CMH) to St. Louis, MO (STL)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from Columbus, OH (CMH) to St. Louis, MO (STL). To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
You'll find the most flights from John Glenn Columbus Intl. (CMH) to Lambert-St. Louis Intl. (STL) on a Friday, with around 63 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Southwest Airlines, American Airlines, and United. Fridays offer notably more flight options compared to other days of the week, making it a popular choice for travellers.
What are the most popular departure times for flights from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The most popular departure times for flights from John Glenn Columbus Intl. (CMH) to Lambert-St. Louis Intl. (STL) are in the early morning, between 6am and 9am. Many major carriers, including Southwest Airlines, American Airlines and Delta, offer flights during this window. Many travellers prefer these times as it allows for an early start to their day in St. Louis.
How long does it take to fly from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Flying nonstop from CMH to STL takes around 1 hour 30 minutes, with the route covering approximately 658 kilometers. Flights with a layover typically take 5 hours longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Yes, you can fly business class or first class between CMH and STL. You can fly business class with Frontier Airlines and Delta.First class cabins are available on Alaska Airlines, Delta, United, and American Airlines.
How do I earn miles on a Columbus, OH (CMH) to St. Louis, MO (STL) flight with Expedia?
It's easy to earn miles on a Columbus, OH (CMH) to St. Louis, MO (STL) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
Is it cheaper to buy a plane ticket from Columbus, OH (CMH) to St. Louis, MO (STL) at the last minute?
Typically, booking a last minute flight from Columbus, OH (CMH) to St. Louis, MO (STL) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Columbus, OH (CMH) to St. Louis, MO (STL) flight and hotel package?
Securing a Columbus, OH (CMH) to St. Louis, MO (STL) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your Columbus, OH (CMH-John Glenn Columbus Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

0
Origin airport
John Glenn Columbus Intl.
Destination airport
Lambert-St. Louis Intl.
Return price
£656
Distance
654 km

Book with confidence

Compare flights from Columbus to St. Louis easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Columbus to St. Louis. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Lambert-St. Louis Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from John Glenn Columbus Intl. to Lambert-St. Louis Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from John Glenn Columbus Intl. (CMH) to Lambert-St. Louis Intl. (STL)

The easiest way to view the best deals on flights from Columbus to St. Louis today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from John Glenn Columbus Intl. to Lambert-St. Louis Intl. start at just £657 and range up to £970.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Columbus and St. Louis
  • booking your flight during August, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Columbus to St. Louis flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from John Glenn Columbus Intl. to Lambert-St. Louis Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Columbus to St. Louis easily and book with confidence

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*Available to Expedia members.