Compare and book 5 Star hotels in St. Louis, Missouri

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Top St. Louis 5 Star Hotels

Our top choices for St. Louis 5-star hotels

The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (546)
"Room was very spacious. The property was immaculate and the service was attentive without be over bearing."
The price is £448
includes taxes & fees
21 Sept - 22 Sept
The Ritz-Carlton, St. Louis
Four Seasons Hotel St Louis
Rooftop bar

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1004)
"We’ve stayed at this hotel several times and keep coming back. Great hotel staff and property. "
The price is £368
includes taxes & fees
2 Sept - 3 Sept
Four Seasons Hotel St Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Louis.
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road, St. Louis, MO
The price is £110 per night from 28 Sept to 29 Sept
£110
28 Sept - 29 Sept
includes taxes & fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What are the best 5-star hotels in St. Louis?
Treat yourself to a luxurious stay at Four Seasons Hotel St Louis. This is among the top 5-star hotels in St. Louis based on Expedia customer reviews. From its guest services to its well-appointed rooms and prime location, you can rely on the highest standard of excellence.
How much does it cost to stay in a 5-star hotel in St. Louis?
You'll find many different pricing options for a 5-star hotel in St. Louis on Expedia. The amount you pay will depend on your travel dates, trip length and other factors. Compare available accommodation for your desired dates and use our pricing and other filters to lock in the ideal high-end stay.

  • Search for the lowest price per night from £109

What makes a hotel 5 stars in St. Louis?
From gourmet dining venues and 24/7 fitness centres to pools and the finest bedding, the 5-star experience in St. Louis is all about indulgence and comfort. But it takes more than just upscale perks to earn a 5-star rating. Accommodation must also deliver remarkable guest-focused services like in-room massage treatments, on-site dry cleaning and laundry and a nightly turn-down service.