Title: TOP Luxury Hotels in Cuba, MO for 2026 - Cuba Upscale Hotels | Expedia.co.uk [Hotels in Cuba](https://expedia.co.uk/Cuba-Hotels.d6499.Travel-Guide-Hotels)[Holiday Rentals in Cuba](https://expedia.co.uk/Cuba-Holiday-Rentals.d6499.Travel-Guide-HolidayRentals)[Flights to Cuba](https://expedia.co.uk/Cheap-Flights-To-Cuba.d6499.Travel-Guide-Flights)[Cuba Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Cuba.d6499.Car-Hire-Guide)[Cuba Holidays](https://expedia.co.uk/Cuba.d6499.Holidays-City-Breaks) ![Historic Route 66 sign.](https://images.trvl-media.com/place/6499/69136be6-ea26-4baa-ae61-87a02ca57354.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Cuba, MO - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Cuba Luxury Hotels Tonight [1 Dec - 2 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6499&startDate=2025-12-01&endDate=2025-12-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [2 Dec - 3 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6499&startDate=2025-12-02&endDate=2025-12-03&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6499&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6499&startDate=2025-12-12&endDate=2025-12-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Cuba Luxury Hotels ![In-room safe, desk, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/870000/861500/861493/e99f99fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking | In-room safe, desk, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/870000/861500/861493/23d9f385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/870000/861500/861493/943aa2e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/870000/861500/861493/b608d22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Cuba Cuba 8.8/10 Excellent (984) "Great place to stay if floating river." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise £69 includes taxes & fees 10 Dec - 11 Dec [](https://www.expedia.co.uk/Rolla-Hotels-Super-8-By-Wyndham-Cuba.h861493.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=6499&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_BF_PROMO_6499) ## Find out more about Cuba ### Cubaand its attractions for luxury travelers Cuba, Missouri, offers several charming points of interest that cater to discerning travellers seeking a luxurious experience. Begin your exploration at the iconic Route 66 mural, where you can snap photos in front of vibrant, eye-catching art that celebrates the historic highway. Following this, indulge in a visit to the local wineries, such as the nearby St. James Winery, where you can enjoy exclusive tastings and vineyard tours, experiencing the rich flavours of regional wines in an elegant setting. For those who appreciate craftsmanship, the Cuba Antique Mall features an extensive collection of antiques and vintage items, perfect for finding unique treasures while enjoying a sophisticated shopping atmosphere. Nature enthusiasts can venture to the picturesque Meramec River, where you can enjoy a serene afternoon of kayaking or fishing, surrounded by stunning landscapes, all while staying in spacious lodges that offer modern amenities. Finally, unwind at one of the upscale hotels located near the downtown area, providing convenient access to these attractions while ensuring a pampered stay with attentive service and luxurious comforts. ## Top Cuba Hotel Reviews ![Greenlight Inn & Suites](https://images.trvl-media.com/lodging/1000000/20000/18300/18239/ad4ef74b_y.jpg) ### Greenlight Inn & Suites 10/10 Excellent "Close to free way. " [](https://expedia.co.uk/Rolla-Hotels-Greenstay-Hotel-Suites.h18239.Hotel-Information) ![Days Inn by Wyndham Rolla](https://images.trvl-media.com/lodging/1000000/50000/40300/40279/1759c9c5_y.jpg) ### Days Inn by Wyndham Rolla 10/10 Excellent "Yes great " [](https://expedia.co.uk/Rolla-Hotels-Days-Inn-By-Wyndham-Rolla.h40279.Hotel-Information) ![Super 8 by Wyndham Cuba](https://images.trvl-media.com/lodging/1000000/870000/861500/861493/e99f99fb_y.jpg) ### Super 8 by Wyndham Cuba 10/10 Excellent "Wonderful stay. Great room. Very clean. Very nice staff!" [](https://expedia.co.uk/Rolla-Hotels-Super-8-By-Wyndham-Cuba.h861493.Hotel-Information) ## Frequently asked questions ### Which area of Cuba is best to stay in for luxury hotels? > The best area to stay in Cuba, Missouri, for luxury hotels is along the historic Route 66 corridor, particularly around the main thoroughfare of East Washington Street. > > > > This area is the heart of Cuba's visitor experience, known for its iconic murals and easy access to local points of interest. It's where you'll find a selection of the town's more established hotels and dining options, offering convenience and a higher standard of amenities. The street is lined with various businesses and provides a straightforward route through the town. > > > > Couples looking for a comfortable and convenient stay will find this area particularly suitable. Hotels here often feature enhanced services and facilities, making it easy to relax after a day of exploring the town's murals or the nearby Meramec River. Many establishments offer premium rooms and attentive service, ensuring a pleasant and stress-free trip. > > > > For solo travellers, staying along East Washington Street provides excellent accessibility to local eateries and shops, all within a manageable distance. ### How much does a luxury hotel in Cuba cost? > Luxury hotel prices in Cuba vary, but you can find a great deal from £69 on Expedia. To find the best prices on luxury stays, be flexible with your dates—typically, off-peak and mid-week stays are cheaper. Sort your search results by "Price: low to high" to see our lowest rates. ### What luxury activities and experiences are there in Cuba? > The best area to stay in Cuba, Missouri, for luxury activities and experiences is typically near the historic Route 66 corridor, particularly around the central part of town where many of its famous murals and local businesses are located. > > > > This area is the heart of Cuba, known for its collection of outdoor murals that depict local history and culture, earning it the title "Route 66 Mural City." You'll find many of these murals along the main thoroughfare, historic Route 66 itself (also known as West Washington Street or Highway 66), and its intersecting streets like Franklin Street. The layout is quite walkable, especially for exploring the murals and local shops. > > > > For couples looking for a relaxed and enriching experience, staying close to the historic Route 66 corridor is ideal. You can easily spend an afternoon strolling along the streets, admiring the famous murals like the "Bette Davis" mural or the "Wagon Wheel Motel" mural, and popping into local antique shops or small eateries. ### How can I save on a luxury hotel in Cuba with Expedia? > There are plenty of ways to save on a luxury hotel in Cuba. Join [One Key™](https://www.expedia.co.uk/welcome-one-key), our free travel rewards programme, to unlock Member Prices across a range of hotels. Typically, booking in advance will help you save on hotel bookings. If you're feeling spontaneous, be sure to check for last-minute deals. ### Is it cheaper to book a luxury Cuba hotel and flights as a package? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package. ### Can I cancel my luxury hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right luxury hotel in Cuba for you. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Bourbon Hotels](https://www.expedia.co.uk/Bourbon-Hotels.d6351832.Travel-Guide-Hotels) - [All-Inclusive Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-All-Inclusive-Hotel.0-0-d227-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Beach Resorts & in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Beach-Hotels.0-0-d227-tBeachHotels.Hotel-Filter-Destinations) - [Boutique Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Boutique-Hotel.0-0-d227-tBoutiqueHotel.Hotel-Filter-Destinations) - [Cheap Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Budget-Hotels.0-0-d227-tBudgetHotels.Hotel-Filter-Destinations) - [Casino Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Casino-Hotel.0-0-d227-tCasinoHotel.Hotel-Filter-Destinations) - 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