Compare and book 4 Star hotels in Panama City, Panamá Province

Most hotels are fully refundable. Because flexibility matters.

Save an average of 15% on thousands of hotels with Expedia Rewards

Search over 2.9 million properties and 550 airlines worldwide

Find properties with these dates

Top Panama City 4 Star Hotels

Hotel La Compania, in the Unbound Collection by Hyatt
4.5 star property
9.8 out of 10, Exceptional, (125)
"I would love to come back here again for my next visit. Excellent hotel and building. Thank you."
The price is £285
includes taxes & fees
13 May - 14 May
Hotel La Compania, in the Unbound Collection by Hyatt
La Concordia Boutique Hotel
4.0 star property
9.6 out of 10, Exceptional, (118)
"Very comfortable beds but there was trouble with the AC. Also very loud disco nearby disturbed sleep until 2:30 AM."
The price is £142
includes taxes & fees
20 May - 21 May
La Concordia Boutique Hotel
Ramada Plaza By Wyndham Panama Punta Pacífica
4.0 star property
9.4 out of 10, Exceptional, (1012)
"Location and Breakfast!"
The price is £81
includes taxes & fees
26 May - 27 May
Ramada Plaza By Wyndham Panama Punta Pacífica
Save an average of 15% on thousands of hotels when you're signed in
Marriott Panama Hotel
4.0 star property
9.2 out of 10, Wonderful, (1002)
"The rooftop bar and pool where I was able to see the sunsetting and how peaceful and felt like it was my personal view. Marriott never disappoints!"
The price is £126
includes taxes & fees
26 May - 27 May
Marriott Panama Hotel
American Trade Hotel
4.5 star property
9.2 out of 10, Wonderful, (384)
"Very friendly and helpful staff "
The price is £227
includes taxes & fees
2 Jun - 3 Jun
American Trade Hotel
Gran Evenia Panama
4.5 star property
9.2 out of 10, Wonderful, (64)
"Nice"
The price is £96
includes taxes & fees
12 May - 13 May
Gran Evenia Panama
Central Hotel Panama Casco Viejo
4.0 star property
9.0 out of 10, Wonderful, (681)
"This hotel is perfectly located in the Old Town. It has a wonderful old world elegance about it, but modern in all respects. The staff very friendly and professional. From the front desk, to the drivers, to the restaurant staff. Breakfast buffet is totally worth it. We would definitely stay again."
The price is £262
includes taxes & fees
12 May - 13 May
Central Hotel Panama Casco Viejo
Residence Inn by Marriott Panama City
4.0 star property
9.0 out of 10, Wonderful, (319)
"Nos encantó, muy cómodas habitaciones, muy bien equipadas, todo funcionó muy bien, excelente trato, las encargadas de limpieza muy amables. Excelente ubicación, sin duda de ahora en adelante será nuestra mejor opción cuando viajemos a Panamá."
The price is £111
includes taxes & fees
1 Jun - 2 Jun
Residence Inn by Marriott Panama City
Best Western Plus Panama Zen Hotel
4.0 star property
9.0 out of 10, Wonderful, (665)
"Excellent Places "
The price is £69
includes taxes & fees
9 Jun - 10 Jun
Best Western Plus Panama Zen Hotel
Waymore Hotel Spa & Casino
4.0 star property
9.0 out of 10, Wonderful, (38)
"I had an EZ, quick, smiling early check out with Chantel & Laura. Thumbs up 👍 👌 for those 2 nice, professional 👍 ladies. "
The price is £83
includes taxes & fees
22 May - 23 May
Waymore Hotel Spa & Casino
Las Americas Golden Tower Panama
4.0 star property
8.8 out of 10, Excellent, (866)
"Very good location for our visit to Panama City. The room was very spacious and comfortable and the team was attentive."
The price is £107
includes taxes & fees
12 May - 13 May
Las Americas Golden Tower Panama
Novotel Panama City
4.0 star property
8.8 out of 10, Excellent, (1004)
"Food, site seeing etc "
The price is £74
includes taxes & fees
26 May - 27 May
Novotel Panama City
Holiday Inn Panama Distrito Financiero, an IHG Hotel
4.0 star property
8.8 out of 10, Excellent, (1003)
"Liked restaurant, Breakfast very good. Room & bathroom very good size and very clean. Big study table, safe, Iron. Best was big size room and bath. "
The price is £78
includes taxes & fees
17 May - 18 May
Holiday Inn Panama Distrito Financiero, an IHG Hotel
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
8.8 out of 10, Excellent, (1003)
"All good"
The price is £134
includes taxes & fees
24 May - 25 May
Courtyard by Marriott Panama Multiplaza Mall
The Westin Panama
4.0 star property
8.8 out of 10, Excellent, (218)
"Great business stay. "
The price is £181
includes taxes & fees
31 May - 1 Jun
The Westin Panama
Marriott Executive Apartments Panama City, Finisterre
4.0 star property
8.8 out of 10, Excellent, (508)
"The staff was very friendly and helpful. The property was safe and clean. It was in a very convenient location, only 3 blocks from a grocery store. Additionally, there are several food places within walking distance to the property, including easy access to the Metro line. I had stayed at this location during a previous trip and it will be my primary location for all future trips."
The price is £84
includes taxes & fees
7 Jun - 8 Jun
Marriott Executive Apartments Panama City, Finisterre
Courtyard by Marriott Panama Metromall
4.0 star property
8.8 out of 10, Excellent, (905)
"the accommodation is excelent"
The price is £174
includes taxes & fees
22 May - 23 May
Courtyard by Marriott Panama Metromall
Sortis Hotel, Spa & Casino, Autograph Collection
4.5 star property
8.6 out of 10, Excellent, (823)
"Property is extremely beautiful!!"
The price is £119
includes taxes & fees
24 May - 25 May
Sortis Hotel, Spa & Casino, Autograph Collection
InterContinental Miramar Panama, an IHG Hotel
4.0 star property
8.6 out of 10, Excellent, (393)
"Excelent option to stay iin Panama, close to every turist location and shopping areas"
The price is £151
includes taxes & fees
24 May - 25 May
InterContinental Miramar Panama, an IHG Hotel
Crowne Plaza Panama Airport, an IHG Hotel
4.0 star property
8.4 out of 10, Very good, (1853)
"An overall good experience"
The price is £100
includes taxes & fees
2 Jun - 3 Jun
Crowne Plaza Panama Airport, an IHG Hotel

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.