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Top 10 Southern Minnesota hotels and places to stay

Our top choices for Southern Minnesota hotels

Kahler Grand Hotel

3.0 star property
8.2 out of 10, Very good, (1532)
"The location is excellent."
Kahler Grand Hotel

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3.0 star property
7.2 out of 10, Good, (1002)
"Loved the kid area in the pool"
The price is £61
includes taxes & fees
25 Aug - 26 Aug
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

AmericInn by Wyndham Rochester Near Mayo Clinic

3.0 star property
8.0 out of 10, Very good, (991)
"It was in a good location near the downtown."
The price is £64
includes taxes & fees
28 Aug - 29 Aug
AmericInn by Wyndham Rochester Near Mayo Clinic

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
9.4 out of 10, Exceptional, (874)
"Excellent and very clean property, beds were amazing "
The price is £103
includes taxes & fees
31 Aug - 1 Sept
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Aspen Suites

3.0 star property
9.0 out of 10, Wonderful, (643)
"Convenient and nice hotel. "
Aspen Suites

The Plaza Hotel & Suites Winona

3.0 star property
8.8 out of 10, Excellent, (1005)
"Overall great location and restaurant connection to the hotel Pool is amazing "
The price is £132
includes taxes & fees
26 Aug - 27 Aug
The Plaza Hotel & Suites Winona

AmericInn by Wyndham Lake City

2.5 star property
9.0 out of 10, Wonderful, (581)
"I love the location and the view. "
The price is £94
includes taxes & fees
14 Sept - 15 Sept
AmericInn by Wyndham Lake City

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
8.8 out of 10, Excellent, (814)
"Great place, staff was friendly. Beds were comfortable. Would stay again. "
The price is £68
includes taxes & fees
12 Sept - 13 Sept
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 star property
8.2 out of 10, Very good, (703)
"Love the location and price"
The price is £76
includes taxes & fees
25 Aug - 26 Aug
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Ramada by Wyndham Albert Lea

3.0 star property
7.4 out of 10, Good, (1002)
"Quiet, clean, great staff"
The price is £60
includes taxes & fees
7 Sept - 8 Sept
Ramada by Wyndham Albert Lea

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3.0 star property
8.4 out of 10, Very good, (1004)
"All staff so friendly and helpful. Twigs restaurant is great."
The price is £105
includes taxes & fees
26 Aug - 27 Aug
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Country Inn & Suites Rochester South Mayo Clinic

3.0 star property
8.4 out of 10, Very good, (1001)
"Nice and quiet neighborhood, but still conveniently located to wherever you need to go."
The price is £68
includes taxes & fees
14 Sept - 15 Sept
Country Inn & Suites Rochester South Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

2.0 star property
8.0 out of 10, Very good, (1003)
"I liked the quietness, cleanliness, and the breakfasts. The bus stop is ever so close. I was happy to see Mayo Clinic is within walking distance.l enjoyed my stay."
The price is £56
includes taxes & fees
5 Sept - 6 Sept
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Mankato

2.0 star property
7.8 out of 10, Good, (1003)
"Very nice hotel"
The price is £51
includes taxes & fees
31 Aug - 1 Sept
Microtel Inn & Suites by Wyndham Mankato

AmericInn by Wyndham Winona

2.5 star property
9.0 out of 10, Wonderful, (834)
"Looks new or newly renovated, nice property, very clean rooms, great breakfast."
The price is £105
includes taxes & fees
7 Sept - 8 Sept
AmericInn by Wyndham Winona

St James Hotel, a Historic Hotel of America

3.5 star property
9.2 out of 10, Wonderful, (1000)
"A historic hotel ! "
The price is £136
includes taxes & fees
25 Aug - 26 Aug
St James Hotel, a Historic Hotel of America

Med City Inn & Suites - Mayo Clinic Area

2.5 star property
8.0 out of 10, Very good, (1004)
"Nice place to stay "
The price is £68
includes taxes & fees
25 Aug - 26 Aug
Med City Inn & Suites - Mayo Clinic Area

Holiday Inn Express Rochester South - Mayo Area by IHG

2.5 star property
8.8 out of 10, Excellent, (1005)
"Great staff and nice clean convenient hotel "
The price is £72
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express Rochester South - Mayo Area by IHG

Aspen Select

3.5 star property
8.4 out of 10, Very good, (1002)
"great receptionist ! "
The price is £112
includes taxes & fees
3 Sept - 4 Sept
Aspen Select

Country Inn & Suites by Radisson, Rochester, MN

2.5 star property
7.6 out of 10, Good, (1003)
"Friendly staff and great rate "
The price is £58
includes taxes & fees
31 Aug - 1 Sept
Country Inn & Suites by Radisson, Rochester, MN
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southern Minnesota, MN

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Accommodation near Southern Minnesota attractions

Learn more about Southern Minnesota

Explore the family-friendly area of Southern Minnesota—an opera house, shopping and sights from Mount Kato Ski Area to Blakeslee Stadium.

Rochester showing skyline and a city
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Top Southern Minnesota Hotel Reviews

Frequently asked questions

Where can I find the best nightlife in Southern Minnesota?
Southern Minnesota is a charming region known for its friendly atmosphere and natural beauty, but the nightlife scene is more subdued compared to larger cities.

In cities like Rochester, you can find a selection of bars and pubs that create a welcoming environment for a relaxed evening out. The downtown area features a variety of options, including microbreweries and cocktail lounges, superb for enjoying a casual night with friends.

Mankato also offers some nightlife options, particularly along Riverfront Drive, where you can discover local bars and live music venues that often host events and performances.

For those seeking a lively atmosphere, the city of Winona has a quaint downtown area with an array of pubs and eateries that make for a delightful night out, especially during the warmer months when outdoor seating is available.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Southern Minnesota hotel for you.
How can I save on a Southern Minnesota hotel booking with Expedia?
Before booking your Southern Minnesota hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia.
How much is the nightly rate at a Southern Minnesota hotel?
Prices for hotels in Southern Minnesota often vary, but you can find a great deal from £57 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.