A calm lake with a row of canoes on the shore and a single canoe on the water.

Find Spa Hotels in Southern Minnesota, MN

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Check availability on Southern Minnesota Spa Hotels

Tonight
3 Sept - 4 Sept
Tomorrow
4 Sept - 5 Sept
This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

Our top choices for Southern Minnesota hotels with a spa

1. Treasure Island Resort & Casino

Treasure Island Resort & Casino
Welch
£74
includes taxes & fees
7 Sept - 8 Sept
Treasure Island Resort & Casino

2. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
Rochester
  • Rejuvenating spa retreats with daily treatments, hot tub relaxation, and attentive staff await at this hotel.
£66
includes taxes & fees
6 Sept - 7 Sept
AmericInn by Wyndham Rochester Near Mayo Clinic

3. St James Hotel, a Historic Hotel of America

St James Hotel, a Historic Hotel of America
Red Wing
  • Rejuvenate at this historic riverside hotel where the full-service spa offers massages and facials for ultimate relaxation.
£143
includes taxes & fees
6 Sept - 7 Sept
St James Hotel, a Historic Hotel of America

4. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
Downtown Rochester
  • Soothing spa treatments and daily wellness rituals await at this city centre Rochester retreat with an indoor pool and hot tub.
£153
includes taxes & fees
18 Sept - 19 Sept
Hilton Rochester Mayo Clinic Area

5. Grandstay Hotel and Suites

Grandstay Hotel and Suites
Waseca
  • Rejuvenate at this hotel's full-service spa with an indoor pool and hot tub for a peaceful wellness retreat.
£87
includes taxes & fees
10 Sept - 11 Sept
Grandstay Hotel and Suites

6. Round Barn Farm B & B Event Center

Round Barn Farm B & B Event Center
Red Wing
  • Relax in a charming bed & breakfast with private hot tubs and deep-tissue massages, surrounded by a peaceful garden setting.
£183
includes taxes & fees
7 Sept - 8 Sept
Round Barn Farm B & B Event Center

7. Mystic Lake Casino Hotel

Mystic Lake Casino Hotel
Prior Lake
  • Revitalise in this serene lakeside resort with 3 spa treatment rooms and a blissful steam room for wellness seekers.
£111
includes taxes & fees
7 Sept - 8 Sept
Mystic Lake Casino Hotel

8. Grand Falls Casino & Golf Resort

Grand Falls Casino & Golf Resort
Larchwood
  • Rejuvenate in a luxury spa sanctuary with 12 treatment rooms and a serene golf course setting for total relaxation.
£120
includes taxes & fees
7 Sept - 8 Sept
Grand Falls Casino & Golf Resort

9. Rodeway Inn Milford

Rodeway Inn Milford
Milford
  • Unwind at this serene retreat with a full-service spa, hot tub, and indoor pool, offering a peaceful escape near West Okoboji Lake.
£78
includes taxes & fees
7 Sept - 8 Sept
Rodeway Inn Milford

10. Omni Viking Lakes Hotel

Omni Viking Lakes Hotel
Eagan
  • Indulge in rejuvenating wellness treatments at this upscale hotel with seven spa rooms and an indoor pool near TCO Performance Centre.
£147
includes taxes & fees
4 Sept - 5 Sept
Omni Viking Lakes Hotel
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Choose what matters most at spa hotels in Southern Minnesota

Pool
Breakfast included
Hot tub
4 stars
5 stars

Spa hotels with hot tubs in Southern Minnesota

Treasure Island Resort & Casino

Treasure Island Resort & Casino
Welch
£74
includes taxes & fees
7 Sept - 8 Sept
Treasure Island Resort & Casino

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
Rochester
£66
includes taxes & fees
6 Sept - 7 Sept
AmericInn by Wyndham Rochester Near Mayo Clinic

Grandstay Hotel and Suites

Grandstay Hotel and Suites
Waseca
£87
includes taxes & fees
10 Sept - 11 Sept
Grandstay Hotel and Suites

Round Barn Farm B & B Event Center

Round Barn Farm B & B Event Center
Red Wing
£183
includes taxes & fees
7 Sept - 8 Sept
Round Barn Farm B & B Event Center

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
Downtown Rochester
£153
includes taxes & fees
18 Sept - 19 Sept
Hilton Rochester Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find out more about Southern Minnesota

Top Southern Minnesota attractions for a relaxing vacation

Southern Minnesota is a hidden gem for travellers seeking a rejuvenating stay at spa hotels. Start your adventure in the vibrant city of Rochester, home to the renowned Mayo Clinic and the stunning Quarry Hill Nature Center, where you can unwind amidst serene landscapes and native wildlife trails. Not far from Rochester, the picturesque Root River State Trail beckons outdoor enthusiasts with its scenic biking and hiking options, allowing for invigorating days spent in nature. For a unique experience, explore the historic charm of Lanesboro, often referred to as the 'Bed and Breakfast Capital of Minnesota', where you can indulge in local culinary delights before retreating to your luxurious spa hotel. The stunning views along the Mississippi River in Winona offer a perfect backdrop for relaxation, particularly after a day of exploring the local wineries and artisan shops. Southern Minnesota boasts several spa hotels that provide exceptional services, attentive staff, and a focus on quality, ensuring a pampered experience that leaves you feeling revitalised. Whether you choose to stay in Rochester or one of the nearby towns, the combination of stunning natural beauty and top accommodations makes for an unforgettable escape.

Top Southern Minnesota Hotel Reviews

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

8/10 Good
"It’s a very long walk to the elevator and its hard to find. If using the shuttle, be sure to plan to be riding for an hour after too."
Crystal 2-night trip
Posted 7 hours ago
Med City Inn & Suites - Mayo Clinic Area
St James Hotel, a Historic Hotel of America

St James Hotel, a Historic Hotel of America

8/10 Good
"Hotel was clean and the staff very friendly. however, there was no refrigerator and the bathroom was small and somewhat outdated"
Maribeth 2-night trip
Posted 8 hours ago
St James Hotel, a Historic Hotel of America
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent
"We had a single queen room. It was modern but a little tight for 2 suitcases. The lobby and check-in desks are on the 2nd floor which wasn't immediately clear to us when we arrived. The location is a 7-15 minute walk for many Mayo appointments. Parking was $16/day but very convenient if added during check-in. Based on my experience this is the same price you'd pay at any other garages downtown. Had a gym. No pool. There was a nice looking restaurant right off of the lobby where you could order meals and room service from."
Jessica 2-night trip
Posted 13 hours ago
Hotel Indigo Rochester – Mayo Clinic Area by IHG
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good
"Check out was very confusing. It took about a half hour and I am still not sure if the billing was correct. Food was fine."
Robert 3-night trip
Posted 6 days ago
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

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