Title: Hotels in Southern Minnesota - Best Southern Minnesota Hotels from £56 - Fully Refundable Options - Expedia.co.uk [Southern Minnesota Travel Guide](https://expedia.co.uk/Southern-Minnesota.dx6059950)[Holiday Rentals in Southern Minnesota](https://expedia.co.uk/Southern-Minnesota-Holiday-Rentals.d6059950.Travel-Guide-HolidayRentals)[Flights to Southern Minnesota](https://expedia.co.uk/Cheap-Flights-To-Southern-Minnesota.d6059950.Travel-Guide-Flights)[Southern Minnesota Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Minnesota.d6059950.Car-Hire-Guide)[Southern Minnesota Holidays](https://expedia.co.uk/Southern-Minnesota.d6059950.Holidays-City-Breaks) ![Lake Pepin & Mississippi River Scenic View](https://images.trvl-media.com/place/553248621532649642/b0facbcd-16cb-4461-946e-105f314f35fc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Southern Minnesota, MN from £56 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Southern Minnesota Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&amenities=SPA_ON_SITE) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&lodging=CABIN) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&amenities=POOL) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&amenities=PETS) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&travelerType=family_friendly) Resort [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&lodging=HOTEL_RESORT) Farm [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&lodging=AGRITOURISM) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&lodging=APARTMENT) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&amenities=WATER_PARK) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&lodging=COTTAGE) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Southern+Minnesota%2C+Minnesota%2C+United+States+of+America®ionId=6059950&latLong=44.057671%2C-94.013694&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&lodging=CONDO) ## Check prices for these dates Tonight [11 Dec - 12 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059950&startDate=2025-12-11&endDate=2025-12-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Dec - 13 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059950&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059950&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059950&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southern Minnesota hotels ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/86c17899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds | Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/f91e65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) Downtown Rochester 8.4/10 Very good (1821) Conveniently located just 5 minutes from Mayo Clinic, this historic hotel offers 2 restaurants including Lord Essex Tavern & Grill. Guests appreciate the helpful staff, clean accommodation, and peaceful atmosphere, plus easy access to Plummer Building. --- "Staff was friendly and helpful! Will continue to stay here while at the Mayo, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gayle £115 includes taxes & fees 17 Dec - 18 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | 1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/290eee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG [](https://www.expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) Downtown Rochester 8.8/10 Excellent (884) Located within walking distance of Mayo Clinic, this hotel offers quiet rooms and convenient access to Rochester Public Library. The on-site Crave restaurant serves American cuisine, while the rooftop terrace provides a serene escape after a busy day. --- "Great room and stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor £81 includes taxes & fees 26 Dec - 27 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Serves lunch, dinner and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/493f76e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3b0f1e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/8d7f7147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) Rochester 8.2/10 Very good (1130) This peaceful hotel offers an indoor pool and 24-hour fitness centre just 5 minutes from Mayo Clinic. Enjoy free breakfast and parking, plus convenient dining at Crooked Pint Ale House. Rooms include refrigerators and microwaves for added comfort. --- "Great location and value" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle £63 includes taxes & fees 26 Dec - 27 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/12906a03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children’s pool](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/f69df08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/dd818bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S [](https://www.expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) Rochester 7.2/10 Good (1018) Located within a 10-minute drive of Mayo Clinic, this Rochester hotel offers complimentary perks including daily buffet breakfast, Wi-Fi, and self parking. Guests can maintain routines at the fitness centre while enjoying clean, comfortable rooms praised by travellers. --- "Breakfast was good. The staff was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kjirsta £60 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/eabb718a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/3613a59b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/b1805314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG [](https://www.expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) Kutzky Park 9.4/10 Exceptional (956) Focused on well-being, this Rochester hotel is a 15-minute walk from Mayo Clinic campuses. Refresh in the indoor pool and hot tub, energise at the 24-hour fitness centre, or relax at the bar after exploring nearby Plummer Building. --- "Rooms are comfortable and staff was was so professional and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William £88 includes taxes & fees 13 Dec - 14 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/7b237c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/94989f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/8b35b717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/10494388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Suites [](https://www.expedia.co.uk/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) Rochester 9.0/10 Wonderful (688) Just 5 minutes from Mayo Clinic, this hotel offers a relaxing indoor pool and hot tub after a long day. Enjoy free breakfast, WiFi, and parking while the attentive staff ensures a stress-free stay near Kutzky Park Tennis Centre. --- "I always stay at this hotel , love it clean comfortable rooms, they gave us vouchers for 4 free meals for Thanksgiving dinner" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy [](https://www.expedia.co.uk/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/5b8e813f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/fdcb0eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/055a808d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/84800/84723/37e2c033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) Rochester 9.0/10 Wonderful (895) This quiet Rochester hotel offers a serene retreat with complimentary full breakfast and parking. Just minutes from Mayo Clinic campuses and convenient to area attractions. The 24-hour fitness centre and helpful staff enhance your stay. --- "Good breakfast..shuttle service is excellent..super nice staff.." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DALE K £54 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/Rochester-Hotels-Econo-Lodge-Mayo-Clinic-Area.h84723.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/937e22b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/63ec118a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/460000/455600/455558/28d8dcf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites Rochester South Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) Rochester 8.4/10 Very good (1003) Just a 10-minute drive from Mayo Clinic, this Rochester retreat features a relaxing hot tub, indoor pool, and fitness centre. Guests appreciate the peaceful atmosphere, helpful staff, and convenient perks like free breakfast, WiFi, and parking. --- "Clean room, fun staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £83 includes taxes & fees 6 Jan - 7 Jan 2026 [](https://www.expedia.co.uk/Rochester-Hotels-Country-Inn-Suites-By-Radisson.h455558.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/fce6cfb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/00ce891c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South [](https://www.expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) Rochester 9.4/10 Exceptional (309) This inviting hotel features a refreshing indoor pool and convenient fitness centre. Just 10 minutes from Mayo Clinic and Saint Marys Campus, it offers free breakfast, WiFi and parking. Staff receive high marks from travellers for their helpfulness. --- "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Abidemi £59 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/18000000/17870000/17860700/17860639/50cdb1ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/18000000/17870000/17860700/17860639/ed1e8ba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/18000000/17870000/17860700/17860639/6c26280a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/18000000/17870000/17860700/17860639/02a78b9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Winona [](https://www.expedia.co.uk/Winona-Hotels-AmericInn-By-Wyndham-Winona.h17860639.Hotel-Information) Winona 9.0/10 Wonderful (892) Experience comfort at this Mississippi River hotel with a rejuvenating hot tub and fitness centre. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby attractions like Remlinger Muscle Cars. The bar offers relaxing drinks after a day of adventures. --- "Nice time with clean accomodations and friendly staff. Will stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JEANETTE £89 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Winona-Hotels-AmericInn-By-Wyndham-Winona.h17860639.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/1213b471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/f4c0d6e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/c7a0b093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rochester Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) Downtown Rochester 9.6/10 Exceptional (543) Conveniently located near Mayo Clinic, this hotel offers 2 restaurants including rooftop dining, plus a rejuvenating spa and indoor pool. Guest rooms feature refrigerators and microwaves for added comfort during medical visits. --- "Very courteous staff, loved the valet guy!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jean £147 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) ![In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/1b6617d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/0c1d91fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/fdc1ffe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116600/116574/43d012a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information) Rochester 7.8/10 Good (1001) Located just a 10-minute drive from Mayo Clinic, this quiet hotel offers complimentary WiFi, parking, and daily on-the-go breakfast. Guests appreciate the helpful staff, safe surroundings, and convenient access to nearby restaurants and attractions. --- "Front staff are so kind and efficient. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda £53 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Microtel-Inn-Suites-By-Wyndham-Rochester-North-Mayo-Clinic.h116574.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/bde7ad17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/7b075080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/d3281bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/24e0abff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Rochester Mayo Clinic Area South [](https://www.expedia.co.uk/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) Rochester 9.6/10 Exceptional (246) Located 5 minutes from Mayo Clinic, this Rochester hotel offers a hot tub and 24-hour fitness centre. Guests love the helpful staff and clean rooms. Enjoy complimentary breakfast, WiFi, and parking while staying close to Apache Mall and Plummer House. --- "Very nice motel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jim £92 includes taxes & fees 20 Dec - 21 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/02cd0879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/222c4dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/bdf57892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys [](https://www.expedia.co.uk/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) Kutzky Park 8.6/10 Excellent (934) "Room was comfortable and convenient.Staff was exceptional.I will stay here when I am next in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel £81 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/f77375e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/a518fccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/10fbc765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brentwood Inn & Suites [](https://www.expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) Downtown Rochester 8.8/10 Excellent (1002) Convenient for medical visits, this hotel is just a 5-minute drive from Mayo Clinic and Saint Marys Campus. Guests love the comfortable beds, helpful staff, and daily continental breakfast served from 6-9 AM. Plummer Building and Shops University Square are located nearby. --- "Room was clean breakfast was good everybody was helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) james £97 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/w2998h3997x0y0-693a0036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/4b144b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/w3000h3995x0y0-7bb98679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) Historic Southwest 8.6/10 Excellent (1002) This quiet hotel offers convenience with an indoor pool and 24-hour fitness centre. A quick walk to Mayo Clinic and hospital, guests love the helpful staff and American cuisine at Twigs Tavern. Free breakfast, parking, and WiFi enhance your Rochester stay. --- "The room was clean, the staff was very friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kenneth £106 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/330000/327900/327884/b6211ad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Jetted Tub (Not Pet Friendly) | Blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/330000/327900/327884/22872847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LED TV](https://images.trvl-media.com/lodging/1000000/330000/327900/327884/f888460e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 indoor pools](https://images.trvl-media.com/lodging/1000000/330000/327900/327884/9d0d772d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Plaza Hotel & Suites Winona [](https://www.expedia.co.uk/Winona-Hotels-The-Plaza-Hotel-Suites-Winona.h327884.Hotel-Information) Winona 8.8/10 Excellent (1000) Tranquil retreat in Winona featuring 2 indoor pools and complimentary breakfast, wifi and parking. Enjoy American cuisine at River City Grill & Bar or unwind at the bar after exploring nearby Sugar Loaf attractions. Convenient location with in-room refrigerators and microwaves. --- "The pools were great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth £100 includes taxes & fees 17 Dec - 18 Dec [](https://www.expedia.co.uk/Winona-Hotels-The-Plaza-Hotel-Suites-Winona.h327884.Hotel-Information) ![Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2555x4y4-921fa2b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/ec5f8616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-014e984a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's [](https://www.expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) Rochester 8.2/10 Very good (785) Situated just minutes from Mayo Clinic, this Rochester hotel offers an indoor pool and hot tub for relaxation after appointments. Enjoy free breakfast, WiFi, and parking, plus American dining at Wildwood Sports Bar. Nearby shops and restaurants enhance the stay. --- "Great place to stay. Freindly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joel £81 includes taxes & fees 17 Dec - 18 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![2 indoor pools](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f8e4d672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f78e7c09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Med City Inn & Suites - Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) Kutzky Park 7.8/10 Good (1002) This family-friendly motel offers 2 indoor pools and a hot tub near Mayo Clinic. Enjoy free breakfast, parking, and WiFi, plus in-room refrigerators and microwaves. Guests love the quiet atmosphere, helpful staff, and proximity to restaurants and shopping. --- "Room was clean, great location, convenient to restaurant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sam £69 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Private kitchenette | Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/67759f7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/ad8fe2d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/43e42846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt House Rochester/Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) Downtown Rochester 9.2/10 Wonderful (1001) Enjoy your stay with an indoor pool, hot tub, and fitness centre at this convenient Rochester hotel. A complimentary shuttle, full breakfast, and in-room kitchenettes enhance your visit. The friendly staff provides exceptional service near Shops University Square. --- "Clean rooms, very friendly staff and was perfect for our stay, was a 5 to 10 minute walk to Mayo clinic. Great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim £111 includes taxes & fees 26 Dec - 27 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27®ionId=6059950&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Southern Minnesota, MN Showing deals for:**19 Dec - 21 Dec** ### Image gallery for The Towers At Kahler Grand Hotel ![Front of property](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/fe413203.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Towers At Kahler Grand Hotel Rochester **9.4/10**Exceptional (94 reviews) 10% off £710 for 2 nights, 1 room £355 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=16119557&adults=2) ### Image gallery for Home2 Suites By Hilton Owatonna ![Terrace/patio](https://images.trvl-media.com/lodging/103000000/102040000/102030600/102030502/1e503579.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Home2 Suites By Hilton Owatonna Owatonna **9.6/10**Exceptional (84 reviews) 20% off £196 for 2 nights, 1 room £98 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=102030502&adults=2) ### Image gallery for Comfort Suites and Conference Center ![Suite, Accessible | 1 bedroom, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/6000000/6000000/5992000/5991960/a61e0b69.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Comfort Suites and Conference Center Worthington **9.0/10**Wonderful (465 reviews) 20% off £229 for 2 nights, 1 room £115 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=5991960&adults=2) ### Image gallery for AmericInn by Wyndham Winona ![Exterior](https://images.trvl-media.com/lodging/18000000/17870000/17860700/17860639/50cdb1ef.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### AmericInn by Wyndham Winona Winona **9.0/10**Wonderful (892 reviews) 15% off £210 for 2 nights, 1 room £105 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=17860639&adults=2) ### Image gallery for Sleep Inn & Suites Marshall - University Area ![Lobby](https://images.trvl-media.com/lodging/8000000/7340000/7332200/7332128/c71126a3.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Sleep Inn & Suites Marshall - University Area Marshall **9.0/10**Wonderful (453 reviews) 20% off £179 for 2 nights, 1 room £90 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=7332128&adults=2) ### Image gallery for Residence Inn by Marriott Rochester Mayo Clinic Area South ![BBQ/picnic Area](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/bde7ad17.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Residence Inn by Marriott Rochester Mayo Clinic Area South Rochester **9.6/10**Exceptional (246 reviews) 10% off £187 for 2 nights, 1 room £94 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=90610605&adults=2) ### Image gallery for Root River Valley Cabin \~ Lanesboro, MN ![Exterior detail](https://images.trvl-media.com/lodging/28000000/27140000/27131000/27130984/6f8c0fe6.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Root River Valley Cabin \~ Lanesboro, MN Lanesboro **10/10**Exceptional (335 reviews) 6% off £363 for 2 nights, 1 cabin £182 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=27130984&adults=2) ### Image gallery for OYO Hotel Lamberton Hwy 14 ![Reception](https://images.trvl-media.com/lodging/40000000/39080000/39077000/39076929/9529cb0a.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### OYO Hotel Lamberton Hwy 14 Lamberton **8.4/10**Very good (128 reviews) 28% off £124 for 2 nights, 1 room £62 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=39076929&adults=2) ### Image gallery for Black Hammer Hus - A Norwegian experience ![Property grounds](https://images.trvl-media.com/lodging/89000000/88260000/88252500/88252498/56c62735.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Black Hammer Hus - A Norwegian experience Spring Grove **10/10**Exceptional (22 reviews) 6% off £546 for 2 nights, 1 room £273 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=88252498&adults=2) ### Image gallery for Lovely Two Bedroom Apartment Off Bike Trail ![Outdoor dining](https://images.trvl-media.com/lodging/71000000/70510000/70505200/70505181/8f05c6d5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Lovely Two Bedroom Apartment Off Bike Trail Cannon Falls **9.8/10**Exceptional (27 reviews) 7% off £213 for 2 nights, 1 home £106 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=70505181&adults=2) ### Image gallery for Bluffside cottage with gorgeous views ![Property grounds](https://images.trvl-media.com/lodging/96000000/95680000/95676300/95676238/0164dd91.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Bluffside cottage with gorgeous views Fountain City **10/10**Exceptional (36 reviews) 7% off £245 for 2 nights, 1 home £123 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=95676238&adults=2) ### Image gallery for Hotel Alexander ![Premium bedding, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107790000/107788100/107788065/395eb8b9.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Alexander Mankato **9.2/10**Wonderful (102 reviews) 15% off £186 for 2 nights, 1 room £93 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=107788065&adults=2) ### Image gallery for Vintage Lustron Home Piece of History ![Smart TV, books](https://images.trvl-media.com/lodging/102000000/101020000/101012600/101012563/w905h683x60y0-0a28dfb4.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Vintage Lustron Home Piece of History Minnesota City **10/10**Exceptional (27 reviews) 7% off £287 for 2 nights, 1 home £144 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=101012563&adults=2) ### Image gallery for Home2 Suites by Hilton Rochester Mayo Clinic Area ![Terrace/patio](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Home2 Suites by Hilton Rochester Mayo Clinic Area Rochester **9.6/10**Exceptional (879 reviews) 20% off £205 for 2 nights, 1 room £102 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=23512633&adults=2) ### Image gallery for Sleeps 15 Beautiful Home on 1.2 Acre lot Minutes from Lakes, boat dock & beach ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69830000/69824400/69824363/d4ff22da.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Sleeps 15 Beautiful Home on 1.2 Acre lot Minutes from Lakes, boat dock & beach Albert Lea **10/10**Exceptional (10 reviews) 6% off £1,087 for 2 nights, 1 home £544 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=69824363&adults=2) ### Image gallery for Brentwood Inn & Suites ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Brentwood Inn & Suites Rochester **8.8/10**Excellent (1,002 reviews) 10% off £193 for 2 nights, 1 room £97 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=10007613&adults=2) ### Image gallery for Quiet, comfortable bed & breakfast in a gorgeous rural setting! ![Terrace/patio](https://images.trvl-media.com/lodging/75000000/74220000/74214200/74214130/628ee909.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Quiet, comfortable bed & breakfast in a gorgeous rural setting! Spring Valley **10/10**Exceptional (96 reviews) 8% off £208 for 2 nights, 1 room £104 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=74214130&adults=2) ### Image gallery for Valley Cabin ![Exterior](https://images.trvl-media.com/lodging/89000000/88140000/88134300/88134280/w904h683x60y0-3cf0fc10.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Valley Cabin Spring Valley **9.2/10**Wonderful (7 reviews) 5% off £163 for 2 nights, 1 cabin £81 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=88134280&adults=2) ### Image gallery for The Wen Inn formerly Andor Wenneson ![Front of property](https://images.trvl-media.com/lodging/104000000/103980000/103979000/103978974/9c86c1be.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Wen Inn formerly Andor Wenneson Peterson **9.8/10**Exceptional (56 reviews) 11% off £192 for 2 nights, 1 room £96 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=103978974&adults=2) ### Image gallery for Grandstay Hotel And Suites Luverne ![Indoor pool](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637459/bdf22633.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Grandstay Hotel And Suites Luverne Luverne **9.2/10**Wonderful (738 reviews) 10% off £190 for 2 nights, 1 room £95 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=5637459&adults=2) ### Image gallery for Quality Inn Marshall near University ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24400/24325/d5eb1334.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Quality Inn Marshall near University Marshall **8.2/10**Very good (471 reviews) 20% off £137 for 2 nights, 1 room £68 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=24325&adults=2) ### Image gallery for Charming two bedroom on the corner, newly renovated with a sweet porch. ![Interior](https://images.trvl-media.com/lodging/93000000/92010000/92006100/92006011/0c80bdb1.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Charming two bedroom on the corner, newly renovated with a sweet porch. Albert Lea **10/10**Exceptional (11 reviews) 6% off £224 for 2 nights, 1 home £112 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=92006011&adults=2) ### Image gallery for Kahler Grand Hotel ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Kahler Grand Hotel Rochester **8.4/10**Very good (1,821 reviews) 10% off £231 for 2 nights, 1 room £115 per night includes taxes & fees [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=25516&adults=2) ### Image gallery for Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area Rochester **8.6/10**Excellent (1,002 reviews) Member Price available £227 for 2 nights, 1 room £114 per night includes taxes & fees [Sign in for Member Price ](https://www.expedia.co.uk/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2025-12-19%26endDate%3D2025-12-21%26selected%3D3556%26adults%3D2) [](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-19&endDate=2025-12-21&selected=3556&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouthern-Minnesota-Hotels.d6059950.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouthern-Minnesota-Hotels.d6059950.Travel-Guide-Hotels) ## Stay near popular Central United States attractions ### Mayo Civic Center 4.5/5 (411 reviews) Catch an event at Mayo Civic Center during your trip to Rochester. Attend a sporting event or simply visit the area's shops. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6126914) ### Mayo Clinic Health System Event Center 4.3/5 (131 reviews) Catch an event at Mayo Clinic Health System Event Center during your trip to Mankato. Discover the cafes and its entertainment venues while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6092519) ### Apache Mall 4.2/5 (584 reviews) During your visit to Rochester, you can find the perfect gifts to bring home at Apache Mall. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6188936) ### Welch Village Ski Area Hit the slopes in Welch with a visit to Welch Village Ski Area. Stroll along the area's riverfront or simply enjoy its cafes. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6092569) ### Rochester Recreation Center 3.8/5 (97 reviews) Catch an event at Rochester Recreation Center during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532649604) ### National Volleyball Center 3.8/5 (92 reviews) Catch an event at National Volleyball Center during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248633849529960) ### Laura Ingalls Wilder Museum 4.3/5 (15 reviews) You can spend time studying the exhibits at Laura Ingalls Wilder Museum in Walnut Grove. Take in the museums while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532649192) ### Shattuck-St. Mary's School 4.8/5 (28 reviews) Explore the campus of Shattuck-St. Mary's School during your trip to Faribault. Visit the shops in this family-friendly area or simply enjoy its cafes. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6127630) ## Learn more about Southern Minnesota Explore the family-friendly area of Southern Minnesota—an opera house, shopping and sights from Mount Kato Ski Area to Blakeslee Stadium. [See all hotels in Southern Minnesota](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27&adults=2®ionId=6059950) ![Lake Pepin & Mississippi River Scenic View](https://images.trvl-media.com/place/553248621532649642/b0facbcd-16cb-4461-946e-105f314f35fc.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Southern Minnesota Hotel Reviews ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 10/10 Excellent "Quiet , clean easy access." [](https://expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg) ### Hyatt House Rochester/Mayo Clinic Area 10/10 Excellent "Staff was friendly and helpful. Clean room." [](https://expedia.co.uk/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "I have stayed here a couple times in the past. The renovations are spot on. The cleanliness was superb. The staff were very friendly. The roll in shower and hearing impaired room worked out great for my health issues. It was an easy check in online. " [](https://expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Staff was friendly and helpful! Will continue to stay here while at the Mayo, " [](https://expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![The Berkman](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07_y.jpg) ### The Berkman 10/10 Excellent "Staff was great, as was the room." [](https://expedia.co.uk/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Yes " [](https://expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![St James Hotel, a Historic Hotel of America](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/c90b9231_y.jpg) ### St James Hotel, a Historic Hotel of America 10/10 Excellent "Lovely room, great restaurant on site, free parking, nice staff." [](https://expedia.co.uk/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 10/10 Excellent "I arrived late at night and the young man checking me in was most helpful and friendly (don't always see this at 11 pm!) Very clean and comfortable room, even including a selection of different thicknesses of pillows! (A bonus for those of us who don't like sleeping with our head a foot up in the air...) Excellent breakfast choices." [](https://expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 10/10 Excellent "Very clean and comfortable. Will definitely stay here again when I return to Rochester." [](https://expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ## More cheap stays in Southern Minnesota ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Med City Inn & Suites - Mayo Clinic Area 435 16th Ave Nw Rochester MN £69 14 Dec - 15 Dec includes taxes & fees 7.8/10 Good! (1,009 reviews) [](https://expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Country Inn & Suites by Radisson, Albert Lea - Austin](https://images.trvl-media.com/lodging/1000000/540000/538500/538443/b75bfa05_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Country Inn & Suites by Radisson, Albert Lea - Austin 2214 E Main St Albert Lea MN £69 5 Jan - 6 Jan 2026 includes taxes & fees 8.8/10 Excellent! (1,004 reviews) [](https://expedia.co.uk/Owatonna-Hotels-Country-Inn-Suites-By-Radisson.h538443.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Rochester-South 1755 S Broadway Rochester MN £71 4 Jan - 5 Jan 2026 includes taxes & fees 9/10 Wonderful! (1,008 reviews) [](https://expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![AmericInn by Wyndham Mankato Event Center](https://images.trvl-media.com/lodging/1000000/210000/200100/200058/5c1d8893_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### AmericInn by Wyndham Mankato Event Center 240 Stadium Road Mankato MN £71 15 Dec - 16 Dec includes taxes & fees 9/10 Wonderful! (1,005 reviews) [](https://expedia.co.uk/Mankato-Hotels-AmericInn-By-Wyndham-Mankato-Event-Center.h200058.Hotel-Information) ![Redwood Lodge](https://images.trvl-media.com/lodging/1000000/10000/2900/2849/2bbc5167_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Redwood Lodge 1382 E Bridge St Redwood Falls MN £88 7 Jan - 8 Jan 2026 includes taxes & fees 8.8/10 Excellent! (747 reviews) [](https://expedia.co.uk/Redwood-Falls-Hotels-Redwood-Lodge.h2849.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brentwood Inn & Suites 123 Fourth Ave. NW Rochester MN £97 14 Dec - 15 Dec includes taxes & fees 8.6/10 Excellent! (1,007 reviews) [](https://expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ## Hotels in Southern Minnesota with star rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 5 properties [](https://expedia.co.uk/4Star-Southern-Minnesota-Hotels.s40-0-d6059950.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 110 properties [](https://expedia.co.uk/3Star-Southern-Minnesota-Hotels.s30-0-d6059950.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 236 properties [](https://expedia.co.uk/2Star-Southern-Minnesota-Hotels.s20-0-d6059950.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### Where can I find the best nightlife in Southern Minnesota? > In cities like Rochester, you can find a selection of bars and pubs that create a welcoming environment for a relaxed evening out. The downtown area features a variety of options, including microbreweries and cocktail lounges, superb for enjoying a casual night with friends. > > > Mankato also offers some nightlife options, particularly along Riverfront Drive, where you can discover local bars and live music venues that often host events and performances. > > > For those seeking a lively atmosphere, the city of Winona has a quaint downtown area with an array of pubs and eateries that make for a delightful night out, especially during the warmer months when outdoor seating is available. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Southern Minnesota hotel booking with Expedia? ### How much is the nightly rate at a Southern Minnesota hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [2 Star Hotels in Southwest Minnesota ](https://www.expedia.co.uk/2Star-Southwest-Minnesota-Hotels.s20-0-d6233999.Travel-Guide-Filter-Hotels) - 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