Title: TOP Luxury Hotels in Southern Minnesota, MN for 2026 - Southern Minnesota Upscale Hotels | Expedia.co.uk [Southern Minnesota Travel Guide](https://expedia.co.uk/Southern-Minnesota.dx6059950)[Hotels in Southern Minnesota](https://expedia.co.uk/Southern-Minnesota-Hotels.d6059950.Travel-Guide-Hotels)[Holiday Rentals in Southern Minnesota](https://expedia.co.uk/Southern-Minnesota-Holiday-Rentals.d6059950.Travel-Guide-HolidayRentals)[Flights to Southern Minnesota](https://expedia.co.uk/Cheap-Flights-To-Southern-Minnesota.d6059950.Travel-Guide-Flights)[Southern Minnesota Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Minnesota.d6059950.Car-Hire-Guide)[Southern Minnesota Holidays](https://expedia.co.uk/Southern-Minnesota.d6059950.Holidays-City-Breaks) ![Lake Pepin & Mississippi River Scenic View](https://images.trvl-media.com/place/553248621532649642/b0facbcd-16cb-4461-946e-105f314f35fc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Southern Minnesota, MN - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Minnesota Luxury Hotels Tonight [21 Dec - 22 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059950&startDate=2025-12-21&endDate=2025-12-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [22 Dec - 23 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059950&startDate=2025-12-22&endDate=2025-12-23&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6059950&startDate=2025-12-26&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059950&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Southern Minnesota luxury hotels ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms | Living area | TV, pay films](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/45535621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds | Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/f91e65d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) Downtown Rochester 8.4/10 Very good (1836) "It was just perfect!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shannon £115 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/480000/471600/471550/c539222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/480000/471600/471550/39a14f28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/480000/471600/471550/0fa2acf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/471600/471550/13696772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Blue Earth [](https://www.expedia.co.uk/Fairmont-Hotels-AmericInn-By-Wyndham-Blue-Earth.h471550.Hotel-Information) Blue Earth 7.8/10 Good (461) "Clean room, comfortable bed, great staff friendly & accomodating" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy £71 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Fairmont-Hotels-AmericInn-By-Wyndham-Blue-Earth.h471550.Hotel-Information) ![2 indoor pools](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Arcade](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/ced48756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f78e7c09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Med City Inn & Suites - Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) Kutzky Park 7.8/10 Good (1005) "Room was clean, great location, convenient to restaurant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sam £65 includes taxes & fees 13 Jan - 14 Jan 2026 [](https://www.expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/f7403b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/0269a226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/416983a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/9f9116a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Northfield [](https://www.expedia.co.uk/Owatonna-Hotels-AmericInn-By-Wyndham-Northfield.h8145327.Hotel-Information) Northfield 8.2/10 Very good (622) "Staff was courteous." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara £83 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Owatonna-Hotels-AmericInn-By-Wyndham-Northfield.h8145327.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855300/855258/71230855.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855300/855258/5b2b2f4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed with Sofa bed, Non Smoking (kitchenette) | In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/1000000/860000/855300/855258/4ed2f878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855300/855258/2ce5782f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Jackson MN [](https://www.expedia.co.uk/Worthington-Hotels-Super-8-By-Wyndham-Jackson-MN.h855258.Hotel-Information) Jackson 8.0/10 Very good (602) "The staff was very helpful, the building is well kept, rooms were clean and spacious. I would stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel £65 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Worthington-Hotels-Super-8-By-Wyndham-Jackson-MN.h855258.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/f9d660c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/70737bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, designer toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/c00e3044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/c50d2d73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coratel Inn & Suites By Jasper Northfield [](https://www.expedia.co.uk/Owatonna-Hotels-Coratel-Inn-Suites-Northfield.h459757.Hotel-Information) Northfield 6.2/10 (657) "Clean room comfortable stay and comfortable bed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla £49 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Owatonna-Hotels-Coratel-Inn-Suites-Northfield.h459757.Hotel-Information) ![Room, 2 Queen Beds | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/053999c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/5e158908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Inn and Suites - Mayo Clinic Area [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) Downtown Rochester 8.0/10 Very good (1522) "We liked the overall general welcoming atmosphere, clean room, friendly staff, large breakfast room and swimming pool." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ruthena £109 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/a518fccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/10fbc765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/f77375e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brentwood Inn & Suites [](https://www.expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) Downtown Rochester 8.8/10 Excellent (1006) "Convenient, clean location and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kaushika £97 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/046c7ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/45a7c6c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/ceaab958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/95539a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Winona [](https://www.expedia.co.uk/Winona-Hotels-Days-Inn-By-Wyndham-Winona.h25338.Hotel-Information) Winona 7.8/10 Good (1001) "Comfortable bed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bridget £49 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Winona-Hotels-Days-Inn-By-Wyndham-Winona.h25338.Hotel-Information) ![Standard Room, 1 Queen Bed, Non Smoking | Blackout curtains, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/c82aecae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/2bd6f3e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/c992fc57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/32e69416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Regency Inn & Suites [](https://www.expedia.co.uk/Owatonna-Hotels-Regency-Inn-Suites.h43416.Hotel-Information) Faribault 7.4/10 Good (627) "Clean room, very helpful front desk staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £63 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/Owatonna-Hotels-Regency-Inn-Suites.h43416.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-04&endDate=2026-01-05®ionId=6059950&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southern Minnesota ### Southern Minnesotaand its attractions for luxury travelers Southern Minnesota is a hidden gem for luxury travellers seeking a blend of natural beauty and refined experiences. Start your journey in Rochester, home to the exquisite Mayo Clinic and the nearby serene Quarry Hill Nature Center, where you can explore scenic trails and enjoy peaceful picnics amidst lush landscapes. For a taste of culture, visit the historic city of Mankato, where the vibrant arts scene and local wineries offer delightful tastings and events, perfect for indulging your palate. The picturesque scenery of the Minnesota River Valley invites guests to enjoy scenic boat tours or private wine tastings at local vineyards, providing a splendid way to unwind. Nature lovers can also immerse themselves in the breathtaking vistas of the bluff country in and around Winona, where luxury lodgings allow you to wake up to stunning river views. For an unforgettable stay, consider the luxurious hotels in Rochester, which offer top amenities and exceptional service, ensuring every aspect of your visit is pampered and tailored to your preferences. ## Top Southern Minnesota Hotel Reviews ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Great place to stay downtown. " [](https://expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Aspen Select](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5_y.jpg) ### Aspen Select 10/10 Excellent "Great location for hospital stay" [](https://expedia.co.uk/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Convenient for my business putposes." [](https://expedia.co.uk/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg) ### Brentwood Inn & Suites 10/10 Excellent "Convenient, clean location and friendly staff" [](https://expedia.co.uk/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "It was an amazing stay. Shuttle to the hospital saved parking headaches. " [](https://expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Clean, comfortable, and having the enclosed walkway to go from the hotel to Mayo was fantastic, especially with it being winter. " [](https://expedia.co.uk/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Hilton Garden Inn Rochester Downtown, MN](https://images.trvl-media.com/lodging/1000000/220000/214700/214679/67ee8968_y.jpg) ### Hilton Garden Inn Rochester Downtown, MN 10/10 Excellent "Clean room. " [](https://expedia.co.uk/Rochester-Hotels-Hilton-Garden-Inn-Rochester-Downtown.h214679.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 10/10 Excellent "Scrambled eggs, sausage, hard boiled eggs, fresh fruit, muffins, bagels nd more" [](https://expedia.co.uk/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 10/10 Excellent "Quiet , clean easy access." [](https://expedia.co.uk/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [2 Star Hotels in Southwest Minnesota ](https://www.expedia.co.uk/2Star-Southwest-Minnesota-Hotels.s20-0-d6233999.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Darfur ](https://www.expedia.co.uk/5Star-Darfur-Hotels.s50-0-d3000348838.Travel-Guide-Filter-Hotels) - [Bingham Lake Hotels ](https://www.expedia.co.uk/Bingham-Lake-Hotels.d553248634983429808.Travel-Guide-Hotels) - [Hotels with Indoor Pools in Bloomington ](https://www.expedia.co.uk/Bloomington-Hotels-Hotels-With-Indoor-Pools.0-0-d6287-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Bloomington ](https://www.expedia.co.uk/Bloomington-Hotels-Luxury-Hotel.0-0-d6287-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Bloomington ](https://www.expedia.co.uk/Bloomington-Hotels-Pet-Friendly-Hotel.0-0-d6287-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - 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