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Our top choices for Mayo Clinic hotels

Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic AreaDowntown Rochester, 0.2 mi from Mayo Clinic
9.6 out of 10, Exceptional, (601 reviews)
The price is £154
includes taxes & fees
5 Jun - 6 Jun

TownePlace Suites by Marriott Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic AreaKutzky Park, 0.2 mi from Mayo Clinic
9.6 out of 10, Exceptional, (525 reviews)
The price is £109
includes taxes & fees
5 Jun - 6 Jun

The Berkman
The BerkmanFolwell, 0.9 mi from Mayo Clinic
9.6 out of 10, Exceptional, (414 reviews)
The price is £153
includes taxes & fees
25 May - 26 May

EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHGKutzky Park, 0.6 mi from Mayo Clinic
9.4 out of 10, Exceptional, (1,004 reviews)
The price is £111
includes taxes & fees
7 Jun - 8 Jun

The Towers At Kahler Grand Hotel
The Towers At Kahler Grand HotelDowntown Rochester, < 0.1 mi from Mayo Clinic
9.4 out of 10, Exceptional, (101 reviews)
The price is £283
includes taxes & fees
25 May - 26 May

Home2 Suites by Hilton Rochester Mayo Clinic Area
Home2 Suites by Hilton Rochester Mayo Clinic Area1.6 mi from Mayo Clinic
9.6 out of 10, Exceptional, (964 reviews)
The price is £101
includes taxes & fees
14 Jun - 15 Jun

Residence Inn by Marriott Rochester Mayo Clinic Area South
Residence Inn by Marriott Rochester Mayo Clinic Area South1.5 mi from Mayo Clinic
9.6 out of 10, Exceptional, (283 reviews)
The price is £118
includes taxes & fees
24 May - 25 May

Staybridge Suites Rochester - Mayo Clinic Area by IHG
Staybridge Suites Rochester - Mayo Clinic Area by IHGKutzky Park, 0.6 mi from Mayo Clinic
9.4 out of 10, Exceptional, (468 reviews)
The price is £125
includes taxes & fees
24 May - 25 May

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. MarysKutzky Park, 1.1 mi from Mayo Clinic
9.4 out of 10, Exceptional, (705 reviews)
The price is £98
includes taxes & fees
22 May - 23 May

Broadway Plaza, Trademark Collection by Wyndham
Broadway Plaza, Trademark Collection by WyndhamDowntown Rochester, 0.2 mi from Mayo Clinic
9.2 out of 10, Wonderful, (177 reviews)
The price is £131
includes taxes & fees
31 May - 1 Jun

Candlewood Suites Rochester Mayo Clinic Area by IHG
Candlewood Suites Rochester Mayo Clinic Area by IHG1.6 mi from Mayo Clinic
9.4 out of 10, Exceptional, (493 reviews)
The price is £80
includes taxes & fees
4 Jun - 5 Jun

Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic AreaDowntown Rochester, 0.3 mi from Mayo Clinic
9.0 out of 10, Wonderful, (1,005 reviews)
The price is £119
includes taxes & fees
31 May - 1 Jun

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint MarysKutzky Park, 0.9 mi from Mayo Clinic
9.2 out of 10, Wonderful, (513 reviews)
The price is £110
includes taxes & fees
22 May - 23 May

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Courtyard by Marriott Rochester Mayo Clinic Area/Saint MarysKutzky Park, 0.9 mi from Mayo Clinic
9.2 out of 10, Wonderful, (797 reviews)
The price is £93
includes taxes & fees
30 May - 31 May

Brentwood Inn & Suites
Brentwood Inn & SuitesDowntown Rochester, 0.2 mi from Mayo Clinic
8.8 out of 10, Excellent, (1,000 reviews)
The price is £96
includes taxes & fees
24 May - 25 May

Aspen Suites
Aspen Suites0.8 mi from Mayo Clinic
9.0 out of 10, Wonderful, (838 reviews)
The price is £121
includes taxes & fees
28 May - 29 May

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHGDowntown Rochester, 0.2 mi from Mayo Clinic
8.8 out of 10, Excellent, (1,000 reviews)
The price is £96
includes taxes & fees
26 May - 27 May

Hilton Garden Inn Rochester Downtown, MN
Hilton Garden Inn Rochester Downtown, MNDowntown Rochester, 0.2 mi from Mayo Clinic
8.8 out of 10, Excellent, (906 reviews)
The price is £105
includes taxes & fees
6 Jun - 7 Jun

Hampton Inn Rochester-South
Hampton Inn Rochester-South1.8 mi from Mayo Clinic
9.0 out of 10, Wonderful, (1,007 reviews)
The price is £87
includes taxes & fees
14 Jun - 15 Jun

Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic Area1.9 mi from Mayo Clinic
9.0 out of 10, Wonderful, (979 reviews)
The price is £61
includes taxes & fees
14 Jun - 15 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Mayo Clinic
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Hilton Rochester Mayo Clinic Area | 9.6 Exceptional 601 reviews | View | ||||||
![]() TownePlace Suites by Marriott Rochester Mayo Clinic Area | 9.6 Exceptional 525 reviews | View | ||||||
![]() The Berkman | 9.6 Exceptional 414 reviews | View | ||||||
![]() EVEN Hotel Rochester - Mayo Clinic Area by IHG | 9.4 Exceptional 1,004 reviews | View | ||||||
![]() The Towers At Kahler Grand Hotel | 9.4 Exceptional 101 reviews | View |
Top Mayo Clinic Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic
8/10 Good
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