The Best Hotels Closest to Mayo Clinic in Rochester - 2026 Updated Prices

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Our top choices for Mayo Clinic hotels

A swimming pool with a glass ceiling, a neon sign for the KAFFLER HOTEL, and a view of the city skyline at dusk.

A bar area with a long counter, multiple bar stools, and a television mounted above the bar.

A banquet hall with round tables, chairs, chandeliers, and a fireplace.

A hotel entrance with a modern design, large windows, and a sign indicating it's a Grand Hotel.

1. Kahler Grand Hotel

Downtown Rochester, < 0.1 mi from Mayo Clinic

Located just moments from Mayo Clinic, this hotel provides a fitness centre and shopping options. Recent reviews highlight its ideal location for medical appointments.

£125

includes taxes & fees

3 Oct - 4 Oct

A poolside area with wicker chairs and potted plants, a tiled floor, and a clear view of the pool.

A hotel room with a sofa, two beds, a large window, and a framed artwork on the wall.

A restaurant with a bar area, wooden chairs, and a stone wall.

A modern building with large windows and a parking lot.

2. Kahler Inn and Suites - Mayo Clinic Area

Downtown Rochester, 0.1 mi from Mayo Clinic

This hotel is immediately next to Mayo Clinic, offering spacious rooms with separate living areas and a fitness centre. Enjoy a complimentary self-serve breakfast and nearby dining options.

£119

includes taxes & fees

24 Oct - 25 Oct

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.

An outdoor dining area with wooden beams, tables, and chairs.

A reception desk with a modern design, featuring a wooden panel and a wall adorned with framed botanical artwork.

3. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester, 0.2 mi from Mayo Clinic

This hotel is a brief walk from Mayo Clinic, offering comfortable flats with separate living rooms. Many visitors appreciate its proximity to city centre dining and the Civic Center.

£93

includes taxes & fees

23 Oct - 24 Oct

A modern living room with a flat-screen TV, a fireplace, comfortable seating, and a large window with a city view.

A modern indoor swimming pool with seating areas and a city view.

A spacious lobby with modern furniture, a spiral staircase, and large windows offering views of the outdoors.

A modern hotel lobby with a curved staircase, seating areas, and large windows.

4. Hilton Rochester Mayo Clinic Area

Downtown Rochester, 0.2 mi from Mayo Clinic

Located a brief walk from Mayo Clinic, this hotel provides a separate living room and a fitness centre. Many dining options and the civic centre are also nearby.

£157

includes taxes & fees

17 Oct - 18 Oct

A coffee shop interior with a wooden counter, menu boards, and seating area.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

A hotel room with a bed, bedside table, and a window with curtains.

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 0.2 mi from Mayo Clinic

This hotel is an easy walk from Mayo Clinic, making it ideal for business travellers. Enjoy connecting rooms and complimentary breakfast close to local dining options.

£120

includes taxes & fees

17 Oct - 18 Oct

A modern indoor patio with a fire feature, seating, and large windows.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.6 mi from Mayo Clinic

This hotel is a quick ride from Mayo Clinic and boasts spacious suites with separate living rooms. Guests appreciate the nearby dining options and fitness centre.

£117

includes taxes & fees

23 Oct - 24 Oct

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern indoor pool area with lounge chairs and a pool.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern bar area with seating and a counter.

7. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 0.3 mi from Mayo Clinic

This hotel sits just around the corner from Mayo Clinic, offering a separate living room and free breakfast. Numerous dining options are within easy walking distance.

£103

includes taxes & fees

17 Oct - 18 Oct

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

A reception area with a curved counter, ceiling lights, and a potted plant.

8. Brentwood Inn & Suites

Downtown Rochester, 0.2 mi from Mayo Clinic

This hotel is a brief walk from Mayo Clinic, providing spacious rooms with separate living areas and complimentary breakfast. Nearby dining options enhance your stay.

£82

includes taxes & fees

3 Oct - 4 Oct

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A reception area with two counters, a patterned wall, and a wooden floor.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

A hotel room with a blue sofa, a wooden bench, a small table with a lamp, a painting of a flower, and a kitchenette in the background.

9. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 0.2 mi from Mayo Clinic

This hotel is a pleasant stroll from Mayo Clinic, offering spacious suites with separate living rooms and a fitness centre. Enjoy easy access to nearby restaurants via a skywalk.

£99

includes taxes & fees

23 Oct - 24 Oct

A modern building with large glass windows and indoor plants.

A modern living room with a beige leather sofa, two wooden coffee tables, and a large window with sheer curtains.

A clean, well-lit food service area with a 'Market To Go!' sign, refrigerated display cases, and a variety of packaged goods.

A modern hotel lobby with a large dining table, wicker chairs, a sofa, and a hanging green plant.

10. Marriott Rochester Mayo Clinic

Downtown Rochester, 0.1 mi from Mayo Clinic

A short walk from Mayo Clinic, this hotel includes a fitness centre and offers free rollaway beds. Nearby, you'll find a variety of restaurants and bars to explore.

£174

includes taxes & fees

17 Oct - 18 Oct

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A restaurant interior with wooden tables, chairs, and a stone wall.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

A garden with a water feature, rocks, and yellow umbrellas.

11. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 0.4 mi from Mayo Clinic

This hotel is a brief walk from Mayo Clinic, providing spacious suites with separate living rooms and a fitness centre. Enjoy complimentary breakfast and nearby dining options.

£94

includes taxes & fees

3 Oct - 4 Oct

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

A modern interior with a large dining table, sofas, and a kitchen area.

12. The Berkman

Folwell, 0.9 mi from Mayo Clinic

A brief ride from Mayo Clinic, this aparthotel provides a separate living room and sofa bed for extra comfort. Guests commend its prime location and nearby dining options.

£137

includes taxes & fees

4 Oct - 5 Oct

An outdoor terrace with tables and chairs, a large umbrella, and a view of a modern building with string lights.

A modern hotel room with a fireplace, a sofa, a TV, and a large window with curtains.

A hotel reception area with a curved reception desk, a refrigerator stocked with snacks, a vending machine, and a large abstract painting on the wall.

13. Residence Inn by Marriott Rochester Mayo Clinic Area

Downtown Rochester, 0.2 mi from Mayo Clinic

This hotel is right beside Mayo Clinic, offering a separate living room and complimentary breakfast. Recent visitors highlight its convenient access to local dining options.

£147

includes taxes & fees

23 Oct - 24 Oct

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

A modern bar area with a long counter, bar stools, and a television screen mounted on the wall.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

14. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.6 mi from Mayo Clinic

This hotel is an easy walk from Mayo Clinic and provides a separate living room, breakfast, and a fitness centre. Many restaurants and bars are nearby, catering to all tastes.

£95

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a wooden ceiling, clear blue water, and seating areas around the pool.

A coffee station with a coffee machine, cups, and a Bigelow tea display.

A wooden wardrobe with a television on top, a small black appliance, and a chair.

A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.

15. Med City Inn & Suites - Mayo Clinic Area

Kutzky Park, 1 mi from Mayo Clinic

This hotel is a quick ride from Mayo Clinic, offering a complimentary breakfast and a fitness centre. Recent reviews highlight its convenience for medical visitors and nearby dining options.

£62

includes taxes & fees

3 Oct - 4 Oct

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

A hotel room with a kitchenette, a dining area with striped chairs, a sofa, a TV, and a window with curtains.

A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.

An outdoor patio area with brick walls, a large arched window, and outdoor seating.

16. Aspen Suites

0.8 mi from Mayo Clinic

This hotel is a quick ride from Mayo Clinic and offers spacious rooms with separate living areas. Enjoy complimentary breakfast and a well-equipped fitness centre nearby dining options.

£123

includes taxes & fees

3 Oct - 4 Oct

A lobby with leather chairs, a reception desk, a TV, and a coffee station.

An outdoor patio with tables and chairs, a sign for Aspen Suites, and a building in the background.

A restaurant with tables and chairs, a trash bin, a coffee machine, and a television displaying a sports game.

A hotel with a modern building featuring a prominent sign, a covered entrance, and a parking area.

17. Aspen Select

Kutzky Park, 0.8 mi from Mayo Clinic

This hotel is a brief ride from Mayo Clinic, offering a separate living room and connecting rooms. Recent reviews highlight the clean, comfortable spaces and complimentary breakfast.

£115

includes taxes & fees

31 Oct - 1 Nov

A modern hotel lobby with multiple seating areas, including a central dining table with chairs, a bar area, and a seating section with cushioned chairs.

A hotel reception desk with a modern design, a clock, and a digital screen.

A modern hotel room with a large bed, two bedside tables, and built-in lighting.

A modern conference room with a long table, multiple chairs, and a wooden partition.

18. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kutzky Park, 0.7 mi from Mayo Clinic

This hotel is a brief ride from Mayo Clinic, offering clean, comfortable rooms and a fitness centre. Enjoy a complimentary breakfast before exploring nearby restaurants and bars.

£97

includes taxes & fees

17 Oct - 18 Oct

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

A conference room with multiple tables and chairs, ceiling fans, and artwork on the walls.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.

19. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 0.9 mi from Mayo Clinic

This hotel is a brief ride from Mayo Clinic. Spacious, clean rooms promise comfort, complemented by a fitness centre and complimentary breakfast. Enjoy nearby restaurants and bars.

£113

includes taxes & fees

15 Oct - 16 Oct

View all properties

Compare popular hotels close to Mayo Clinic

Property	Property class	Guest rating
The Berkman	9.6 Exceptional 445 reviews	View
Hilton Rochester Mayo Clinic Area	9.6 Exceptional 647 reviews	View
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys	9.2 Wonderful 804 reviews	View
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys	9.2 Wonderful 538 reviews	View
Broadway Plaza, Trademark Collection by Wyndham	9.2 Wonderful 183 reviews	View

Top Mayo Clinic Hotel Reviews

Kahler Grand Hotel

10/10 Excellent

"This is a grand hotel - stately, convenient and a delightful place to stay. Loved the walkable "subway" connecting the hotel to restaurants and Mayo Clinic. Enjoyed the Architecture and history of the Plummer Bldg."

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"It was very convenient for my Mayo appointment. The shuttle worked out great and the drivers were very friendly and helpful. Breakfast was amazing and ready very early. Food was also excellent at Twigs. We ordered room service since we got there late and had an early appointment. Would definitely stay here again."

AmericInn by Wyndham Rochester Near Mayo Clinic

8/10 Good

"When I tried to call the motels etc by Rochester Mayo. I’d always get Expedia. And we got to go a day early and we still got charged. I thought they had breakfast but my husband said they didn’t. He took our disabled son there.had a nice kitchen nice room pretty clean. Nice staff. Wish it had tubs for adults."

Aspen Select

10/10 Excellent

"access to the property"

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Love this hotel! Within close proximity to Mayo Clinic. Very clean, comfortable beds and great amenities. Our number one go to when we stay in Rochester."

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good

"Overall it was a good stay. Pros: this hotel has the underground tunnel connected to the hospital so it was easy walking over, expecially since there is massive construction going on right there. Hotel was clean, staff was wonderful, breakfast was a good variety and good. Rooms were quiet, never heard any of the construction! A detail I may have missed or it wasn’t added in the description was if you parked in there ramp it was 17 dollars a night. Cons: defiantly needs some updating, but biggest con was the room we had was definitely not handicap accessible at all for the bathroom. Being “connect” to the hospital and the amount of the elderly I would think it would have something there. Toilet was so low almost ment for a child, and extremely tiny room, no grab bars, and step in shower/tub. I would stay here again, most definitely but not if I had elderly with me again"

Brentwood Inn & Suites

10/10 Excellent

"Staff was very helpful and kind. Desk chair worn and could use a replacement-normally would not care but was working remote while there. Wi-Fi great"

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

10/10 Excellent

"Had great help from staff."

TownePlace Suites by Marriott Rochester Mayo Clinic Area

8/10 Good

"Lovely spot and spaces. Rooms large and more than adequate, Only negative was that the rooms smelled a little "moldy.""

Frequently asked questions

What are the top-rated hotels near Mayo Clinic?

Discovering the top-rated hotels near Mayo Clinic ensures a comfortable and convenient stay during your visit to Rochester, Minnesota.Home2 Suites by Hilton Rochester Mayo Clinic AreaHome2 Suites by Hilton Rochester Mayo Clinic Area is a welcoming 3-star hotel located just 4.5 km from Mayo Clinic, rated 9.6 by travellers. Guests appreciate the modern amenities, including a kitchenette with a dishwasher and microwave, as well as a cozy sofa bed. The hotel features complimentary daily breakfast and an accessible indoor pool, making it a perfect choice for those seeking a relaxed atmosphere. With additional perks like Egyptian cotton sheets and a fitness centre, this hotel ensures comfort and convenience for every traveler.Residence Inn by Marriott Rochester Mayo Clinic Area SouthResidence Inn by Marriott Rochester Mayo Clinic Area South is another excellent option, situated 4.5 km from Mayo Clinic and a review rating of 9.6. This 3-star hotel offers spacious rooms with full kitchens and a convenient wet bar, ideal for longer stays. Guests can enjoy a complimentary breakfast and take advantage of the indoor pool and hot tub. The fitness centre is accessible 24 hours, ensuring travellers can maintain their routine while away from home.Fairfield Inn & Suites Rochester Mayo Clinic Area/St. MarysFairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys is perfectly located just 2.4 km from Mayo Clinic, earning an impressive review rating of 9.6. This hotel features comfortable suites and an inviting atmosphere, complete with an indoor pool and a rooftop garden for relaxation. Guests can enjoy complimentary breakfast and easy access to an onsite tennis court, making it a great choice for those looking to stay active during their visit.

What hotels are within walking distance to Mayo Clinic?

Discover the convenience of top-rated hotels within walking distance to Mayo Clinic, perfect for travellers seeking comfort and accessibility.Hilton Rochester Mayo Clinic AreaHilton Rochester Mayo Clinic Area is a welcoming 3.5-star hotel located just a 6-minute walk from Mayo Clinic, with an impressive review rating of 9.6. This hotel features an indoor pool, a full-service spa offering massages and aromatherapy treatments, and a fitness centre open 24 hours. Guests can also enjoy relaxing moments in the hot tub and steam room, making it an excellent choice for relaxation after a day at the clinic.TownePlace Suites by Marriott Rochester Mayo Clinic AreaTownePlace Suites by Marriott Rochester Mayo Clinic Area is a cozy 3-star hotel that is only a 5-minute stroll from Mayo Clinic, rated 9.6 by travellers. It offers a complimentary buffet breakfast and 24-hour fitness facilities. Guests appreciate the rooftop garden and the convenience of in-room kitchens, perfect for those looking to prepare their own meals. The hotel also provides free area shuttle services, adding to its overall convenience for travellers.Staybridge Suites Rochester - Mayo Clinic Area by IHGStaybridge Suites Rochester - Mayo Clinic Area by IHG is a comfortable 3-star hotel located a 12-minute walk from Mayo Clinic, with a solid review rating of 9.4. This hotel features an indoor pool and a hot tub, along with spacious suites equipped with kitchens and premium bedding. Guests can enjoy a complimentary breakfast daily and take advantage of the free area shuttle service, making it an ideal base for those visiting the clinic.

How much is a hotel near Mayo Clinic?

Staying near Mayo Clinic is a treat, with plenty of hotels from £43 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during weekends or around public holidays.

What are the most popular family-friendly hotels near Mayo Clinic?

For families visiting Mayo Clinic, finding the perfect family-friendly hotel is essential for a comfortable stay. Here are some of the top-rated options that cater to families.Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaLocated just an 8-minute walk from Mayo Clinic, the Centerstone Plaza Hotel Soldiers Field is a family-friendly haven with a review rating of 8.4 and a 3-star rating. This hotel features an indoor pool with a children's area, free daily breakfast, and kitchens in select rooms, perfect for families. Guests will appreciate the comfortable accommodations and easy access to the clinic.Med City Inn & Suites - Mayo Clinic AreaMed City Inn & Suites offers an inviting atmosphere just 2.1 km from Mayo Clinic, perfect for families. With a great traveler rating score of 8.0, this hotel features a fantastic waterslide and a children's pool to keep the little ones entertained. Guests can also enjoy complimentary breakfast, a kitchenette in the rooms, and a game room designed for family fun, ensuring a memorable stay.Kahler Grand HotelJust a 3-minute walk from Mayo Clinic, Kahler Grand Hotel is an ideal family-friendly choice with a review rating of 8.2 and a 3-star rating. Families will enjoy amenities like free cribs, connecting rooms, and a children's menu at the on-site restaurant. With its indoor pool and convenient location, travellers can easily balance relaxation and access to the clinic.

What are the best affordable hotels near Mayo Clinic?

Finding a budget-friendly hotel near Mayo Clinic can enhance your stay and provide peace of mind during your visit. Here are some top-rated options that offer great amenities without breaking the bank.Home2 Suites by Hilton Rochester Mayo Clinic AreaHome2 Suites by Hilton Rochester Mayo Clinic Area is a 3-star hotel located just 4.5 km from Mayo Clinic, with an impressive review rating of 9.6. This family-friendly hotel features complimentary breakfast daily, including a buffet on weekends, and offers a variety of amenities such as a fitness centre, free WiFi, and a kitchenette in each suite. Guests can also enjoy the convenience of free area shuttle service and on-site grocery shopping service.Residence Inn by Marriott Rochester Mayo Clinic Area SouthResidence Inn by Marriott Rochester Mayo Clinic Area South is another excellent 3-star option, situated 4.5 km from Mayo Clinic with a stellar review rating of 9.6. Ideal for families, this hotel features a complimentary continental breakfast and an indoor pool perfect for relaxation. Guests will appreciate the fully equipped kitchens in the suites, free WiFi, and accessible fitness facilities to maintain their routine while traveling.Fairfield Inn & Suites Rochester Mayo Clinic Area/St. MarysFairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys stands out with a prime location just 2.4 km from Mayo Clinic and a popular review rating of 9.6. This family-friendly hotel offers free breakfast options and access to an indoor pool, making it a great choice for leisure and relaxation. Additional amenities include free parking, WiFi, and a fitness centre, ensuring travellers have all they need for a comfortable stay.

Are there any hotels with pools close to Mayo Clinic?

If you're looking for hotels with pools near Mayo Clinic, Rochester offers some great options that cater to travellers seeking relaxation and comfort during their stay.Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area is located only 8 minutes from Mayo Clinic and has an excellent review rating of 8.4. This hotel offers an indoor pool with features for children and accessibility options. Guests can also take advantage of free buffet breakfast, 24-hour fitness facilities, and easy access to nearby golf courses and historical sites.Best Western Rochester Hotel Mayo Clinic Area/St. Mary'sBest Western Rochester Hotel Mayo Clinic Area/St. Mary's is conveniently located just 3.5 km from Mayo Clinic, making it an ideal choice for travellers. With an impressive review rating of 8.2, this hotel features an indoor pool complete with a waterslide and children's area—perfect for families. Guests can also enjoy free breakfast, a hot tub, and easy access to local golf courses.Kahler Inn and Suites - Mayo Clinic AreaKahler Inn and Suites - Mayo Clinic Area is just a 3-minute walk from Mayo Clinic and boasts a great traveler rating score of 7.8. This family-friendly hotel features an indoor pool with accessibility options, making it suitable for everyone. Guests can enjoy amenities like a kitchenette in the rooms, free breakfast, and covered parking, ensuring a comfortable stay.

What are the best pet-friendly hotels near Mayo Clinic?

For travellers seeking pet-friendly accommodations near the Mayo Clinic, these top-rated hotels offer welcoming stays for both you and your furry friend.Residence Inn by Marriott Rochester Mayo Clinic Area SouthResidence Inn by Marriott stands out with an impressive 9.6 travellers' rating and is located 4.5 km from the Mayo Clinic. This 3-star hotel allows both dogs and cats, making it a perfect choice for travellers with pets. Guests will appreciate the complimentary breakfast, an indoor pool, and a fitness centre. Additional features include a fully equipped kitchen in every suite and convenient parking options.Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaCenterstone Plaza Hotel Soldiers Field is just an 8-minute walk from the Mayo Clinic and has a welcoming atmosphere for pets, earning a review rating of 8.4. This 3-star hotel features an indoor pool, free buffet breakfast, and a fitness centre. Guests can also enjoy nearby golf, a terrace, and family-friendly amenities such as cribs and kid-friendly meals.Med City Inn & Suites - Mayo Clinic AreaMed City Inn & Suites is a cozy and inviting option just 2.1 km from the Mayo Clinic, with a solid review rating of 8.0. This pet-friendly hotel welcomes dogs and offers essential amenities like free breakfast, an indoor pool, and a hot tub, ensuring a comfortable stay. Guests can also enjoy a fitness centre, kitchenette options, and complimentary toiletries.

Can I book a fully refundable hotel close to Mayo Clinic?

Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Mayo Clinic", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.

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Search Hotels Near Mayo Clinic, Rochester

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Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mayo Clinic hotels

1. Kahler Grand Hotel

2. Kahler Inn and Suites - Mayo Clinic Area

3. Hotel Indigo Rochester – Mayo Clinic Area by IHG

4. Hilton Rochester Mayo Clinic Area

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

7. Hyatt House Rochester/Mayo Clinic Area

8. Brentwood Inn & Suites

9. Hilton Garden Inn Rochester Downtown, MN

10. Marriott Rochester Mayo Clinic

11. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

12. The Berkman

13. Residence Inn by Marriott Rochester Mayo Clinic Area

14. Staybridge Suites Rochester - Mayo Clinic Area by IHG

15. Med City Inn & Suites - Mayo Clinic Area

16. Aspen Suites

17. Aspen Select

18. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

19. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Compare popular hotels close to Mayo Clinic

Top Mayo Clinic Hotel Reviews

Kahler Grand Hotel

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

AmericInn by Wyndham Rochester Near Mayo Clinic

Aspen Select

EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kahler Inn and Suites - Mayo Clinic Area

Brentwood Inn & Suites

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Frequently asked questions

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