Title: All Hotels by Motel 6 in Upstate South Carolina - 2026 Updated Prices | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![Almost every site in this campground is on the lake. Oddly, the entrance gate is locked every night at 10pm. But the trees and lake are beautiful! Peaceful and fullnof birds!](https://images.trvl-media.com/place/144669/e945b35d-16b4-408c-818b-68622e164446.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by RVLuckyorWhat # Search Hotels by Motel 6 in Upstate South Carolina from £41 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-11&endDate=2026-01-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-12&endDate=2026-01-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina Motel 6 ![Fridge, microwave, freezer](https://images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/af5363f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/d0cbf5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/b40fcbc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/c8858fa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Greenville, SC [](https://www.expedia.co.uk/Greenville-Hotels-Motel-6-Greenville.h1107497.Hotel-Information) Greenville 5.2/10 (736 reviews) "Wonderful staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna £41 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Greenville-Hotels-Motel-6-Greenville.h1107497.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36830000/36824600/36824597/6f7f191d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36830000/36824600/36824597/60a1e95b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/37000000/36830000/36824600/36824597/61de02d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/37000000/36830000/36824600/36824597/ca766313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Greenville, SC - I-85 Near Downtown [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Motel-6-Greenville.h36824597.Hotel-Information) Greenville 7.0/10 Good (371 reviews) "I always get what i need from the front desk nice people" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kyerrah £46 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Motel-6-Greenville.h36824597.Hotel-Information) ![Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/104000000/103060000/103059200/103059155/38900136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103060000/103059200/103059155/b09ac693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, towels, soap, toilet paper](https://images.trvl-media.com/lodging/104000000/103060000/103059200/103059155/c27c9604.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/104000000/103060000/103059200/103059155/dca35443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Spartanburg, Sc – Northwest / Business 85 [](https://www.expedia.co.uk/Spartanburg-Hotels-Motel-6-Spartanburg.h103059155.Hotel-Information) Spartanburg 7.2/10 Good (73 reviews) "Old building. Not well kept. Piles of dog poop everywhere. Holes in the sheets. It was basic shelter. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roger £64 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Spartanburg-Hotels-Motel-6-Spartanburg.h103059155.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/085635e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/0200d1b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/837914fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/c5eede06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Simpsonville, SC - Greenville [](https://www.expedia.co.uk/Simpsonville-Hotels-Motel-6-Simpsonville.h328810.Hotel-Information) Simpsonville 7.4/10 Good (358 reviews) "Helpful and nice staff, convenient location off the interstate. Decent room for the price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin £57 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Simpsonville-Hotels-Motel-6-Simpsonville.h328810.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-25&endDate=2026-01-26®ionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Motel-6.0-0-d6057939--bMotel6.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Motel-6.0-0-d6057939--bMotel6.Travel-Guide-Filter-Hotels) ## Top Upstate South Carolina Hotel Reviews ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Room was ckean, staff was friendy, breakfast was great, and hotel was quiet." [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Great" [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "It was wonderful, staff was very nice" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "Awesome " [](https://expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Clean and Comfortable" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "The staff especially stood out. The online check in and the front desk was an absolute breeze! I am pleased as all heck. The room was clean and is well laid out for me to work. I greatly appreciate it." [](https://expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Staff was really nice " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Breakfast is extra" [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg) ### ECHO Suites Extended Stay by Wyndham Spartanburg 10/10 Excellent "Yes" [](https://expedia.co.uk/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ## Explore a world of travel with Expedia - 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