A bench, a bicycle, and a lake surrounded by trees.

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Check availability on Upstate South Carolina Luxury Hotels

Tonight
19 Oct - 20 Oct
Tomorrow
20 Oct - 21 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Upstate South Carolina luxury hotels

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
An outdoor patio with wicker furniture, a round table, and a fountain.

1. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
£158
includes taxes & fees
30 Oct - 31 Oct
The Shepherd Hotel Downtown Clemson
A white, two-story house with a front porch, surrounded by trees and shrubs.
A dining area with round tables, black chairs, and white tablecloths.
A two-story building with a white exterior, a front door, and a balcony.
A bedroom with two beds, a TV, and a fireplace.

2. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
Pendleton
£76
includes taxes & fees
20 Oct - 21 Oct
Liberty Hall Bed and Breakfast
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

3. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
£125
includes taxes & fees
17 Nov - 18 Nov
The Abernathy of Clemson
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A restaurant with a stone fireplace, hanging crystal chandelier, and multiple dining tables set with white tablecloths and wine glasses.
A bar with a large window view of mountains and a chandelier.
A swimming pool with lounge chairs and a building with balconies.

4. Hotel Domestique

Hotel Domestique
Travelers Rest
£346
includes taxes & fees
25 Oct - 26 Oct
Hotel Domestique
A swimming pool with lounge chairs and umbrellas, surrounded by brick buildings with large windows.
A spacious living room with a large window, a dining area with a wooden table and chairs, a sofa, and a small side table.
A modern kitchen with white cabinets, stainless steel appliances, and a wooden ceiling.
An indoor climbing wall with various colored holds and a wooden structure.

5. Spacious Sanctuary | Near DT Action

Spacious Sanctuary | Near DT Action
Greenville
£207
includes taxes & fees
25 Oct - 26 Oct
Spacious Sanctuary | Near DT Action
Exterior
Terrace/patio
Dining
Interior

6. Bed & Breakfast on Tiffany Hill

Bed & Breakfast on Tiffany Hill
Mills River
£234
includes taxes & fees
16 Nov - 17 Nov
Bed & Breakfast on Tiffany Hill
A hotel room with a bed, a desk, a television, and a ceiling fan.
A large, multi-story building with a stone facade, situated in a valley surrounded by autumn-colored trees.
A rustic water wheel in a forested area with autumn foliage.
A waterfall cascading over rocks surrounded by dense green foliage.

7. Bright's Creek Lodge - King Room- Near Tryon and TIEC & Hendersonville

Bright's Creek Lodge - King Room- Near Tryon and TIEC & Hendersonville
Mill Spring
£198
includes taxes & fees
25 Oct - 26 Oct
Bright's Creek Lodge - King Room- Near Tryon and TIEC & Hendersonville
A bedroom with a bed, a sofa, a dresser, and a ceiling fan.
A spacious room with hardwood flooring, a fireplace, a dining table, and a large window with a view.
A porch with two wicker chairs and a small table, a green door, and a window with a view of the backyard.
A two-story house with a front porch, a driveway, and a well-maintained lawn.

8. Opal and West House

Opal and West House
Shelby
£157
includes taxes & fees
1 Nov - 2 Nov
Opal and West House
Interior
Room
Private kitchen
Room

9. ~Cree’s Retreat in the Heart of Brevard~

~Cree’s Retreat in the Heart of Brevard~
Brevard
£159
includes taxes & fees
9 Nov - 10 Nov
~Cree’s Retreat in the Heart of Brevard~
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Top Upstate South Carolina Hotel Reviews

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

10/10 Excellent
"Clean room and great front desk staff. We didn't get to use any of the facilities as we were in town for a concert and arrived late, but the hotel was great. Will definitely stay here again. The price was very reasonable, too."
Mary 1-night trip
Posted 2 hours ago
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"Everything about our stay was great; the staff was very accommodating, and the facilities were top-notch. The breakfast was the best continental breakfast that I have experienced and I will definitely use Embassy if in Greenville area again."
Matthew 1-night trip
Posted 5 hours ago
Embassy Suites Greenville Golf Resort & Conference Center
Hilton Greenville

Hilton Greenville

8/10 Good
"I enjoy my vacation at the Hilton. Although the rooms were clean but dated. And I appreciated the security of having the room key to access the elevator it saw so what annoying when your hands were full to get the elevator to go to the floor you were on. Staff was friendly. and I didn’t check out any of the amenities, but I do know they were available."
Bevelyn 2-night trip
Posted 11 hours ago
Hilton Greenville
Hyatt Regency Greenville

Hyatt Regency Greenville

10/10 Excellent
"It was really clean and nice"
Vinutha 2-night trip
Posted 2 days ago
Hyatt Regency Greenville

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