Title: All Hotels by La Quinta Inn & Suites in Upstate South Carolina - 2025 Updated Prices | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d6057939.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d6057939.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d6057939.Holidays-City-Breaks) ![Greenville - Spartanburg which includes views, tranquil scenes and mountains](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels by La Quinta Inn & Suites in Upstate South Carolina from £66 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [9 Oct - 10 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-10-09&endDate=2025-10-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6057939&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina La Quinta Inn & Suites Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking (1 King Bed) | Premium bedding, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/5fb93bc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/9b41a13e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/1999d91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Greenville Haywood Greenville 7.4/10 Good (1078) "Clean room, nice staff, and convenient location. " £66 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/92684d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast ](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/90c94920.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/904caca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. Greenville 7.6/10 Good (18) "Great place, service, amenities and price!" £74 includes taxes & fees 17 Oct - 18 Oct [](https://www.expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-23&endDate=2025-10-24®ionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-La-Quinta-Inn-Suites.0-0-d6057939--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-La-Quinta-Inn-Suites.0-0-d6057939--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Upstate South Carolina Hotel Reviews ![The Shepherd Hotel Downtown Clemson](//images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "The staff was very accommodating, the decor was beautiful and the room was comfortable. The roof deck was a great spot to relax during the day. It was a little loud at night, especially being on the 2nd floor directly below the bar. But overall it was a great stay." [](https://expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](//images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Nice quiet, clean room. Met our expectations." [](https://expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Baymont by Wyndham Greenville Woodruff Rd](//images.trvl-media.com/lodging/1000000/20000/12300/12266/e0489212_y.jpg) ### Baymont by Wyndham Greenville Woodruff Rd 10/10 Excellent "Yes!" [](https://expedia.co.uk/Greenville-Hotels-Baymont-By-Wyndham-Greenville-Woodruff-Rd.h12266.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "I enjoyed my stay here. It was very clean and cozy. I will make another stay here, if available for my next travel. Thank you! " [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](//images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Very nice property. I would stay there again." [](https://expedia.co.uk/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Very friendly. Great coffee and breakfast. Hotel was clean and convenient " [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Hyatt Place Greenville Downtown](//images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0_y.jpg) ### Hyatt Place Greenville Downtown 10/10 Excellent "Enjoyed our stay and conveniently located to Main Street and restaurants & entertainment." [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Woodspring Suites Greenville Airport](//images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/69b6f44b_y.jpg) ### Woodspring Suites Greenville Airport 10/10 Excellent "Very clean. Right off the interstate. Dog friendly. Only negative would be the pot smoke in the dog area. " [](https://expedia.co.uk/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Everything is super nice and clean" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in Greenville](https://www.expedia.co.uk/5Star-Greenville-Hotels.s50-0-d1388.Travel-Guide-Filter-Hotels) - [Hotels near Discovery Island Water Park](https://www.expedia.co.uk/Discovery-Island-Water-Park-Hotels.0-l553248621532656705-0.Travel-Guide-Filter-Hotels) - [Hotels near Donaldson Center](https://www.expedia.co.uk/Donaldson-Center-Airport-Hotels.0-aGDC-0.Travel-Guide-Filter-Hotels) - 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[Flights from Greenville](https://www.expedia.co.uk/lp/flights/1388/flights-from-greenville) - [Flights from Dunean](https://www.expedia.co.uk/lp/flights/553248634999354841/flights-from-dunean) - [Flights from Simpsonville](https://www.expedia.co.uk/lp/flights/6239/flights-from-simpsonville) - [Flights from Augusta (AGS) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/ags/gmu/augusta-to-greenville) - [Flights from Anderson (AND) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/and/gmu/anderson-to-greenville) - [Flights from Atlanta (ATL) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/atl/gmu/atlanta-to-greenville) - [Flights from Clemson (CEU) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/ceu/gdc/clemson-to-greenville) - [Flights from Washington (DCA) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/dca/gdc/washington-to-greenville) - [Flights from Detroit (DTW) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/dtw/gmu/detroit-to-greenville) - [Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/ewr/gmu/newark-liberty-intl-airport-to-greenville) - [Flights from Gaithersburg (GAI) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/gai/gmu/gaithersburg-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/grd/gmu/greenwood-to-greenville) - [Flights from Hagerstown (HGR) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/hgr/gmu/hagerstown-to-greenville) - [Flights from Hong Kong (HKG) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/hkg/gdc/hong-kong-to-greenville) - [Flights from Islip (ISP) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/isp/gmu/islip-to-greenville) - [Flights from Jacksonville (JAX) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/jax/gmu/jacksonville-to-greenville) - [Flights from Las Vegas (LAS) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/las/gmu/las-vegas-to-greenville) - [Flights from Los Angeles (LAX) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/lax/gmu/los-angeles-to-greenville) - [Flights from Pickens (LQK) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/lqk/gdc/pickens-to-greenville) - [Flights from Morgantown (MGW) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/mgw/gmu/morgantown-to-greenville) - [Flights from Dayton (MGY) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/mgy/gmu/dayton-to-greenville) - [Flights from Madison (MSN) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/msn/gdc/madison-to-greenville) - [Flights from New Orleans (MSY) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/msy/gmu/new-orleans-to-greenville) - [Flights from Paris (PAR) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/par/gdc/paris-to-greenville) - [Flights from Rocky Mount (RWI) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/rwi/gmu/rocky-mount-to-greenville) - [Flights from Louisville (SDF) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/sdf/gmu/louisville-to-greenville) - [Flights from St. Louis (STL) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/stl/gmu/st-louis-to-greenville) - [Flights from Taipei (TPE) to Greenville (GDC)](https://www.expedia.co.uk/lp/flights/tpe/gdc/taipei-to-greenville) - [Discovery Island Water Park](https://www.expedia.co.uk/Discovery-Island-Water-Park-Greenville.d553248621532656705.Attraction) - [Frankie's Fun Park](https://www.expedia.co.uk/Frankies-Fun-Park-Greenville.d553248621532656780.Attraction) - [Greenville Holidays](https://www.expedia.co.uk/Greenville.d1388.Holidays-City-Breaks) - [Visit Greenville](https://www.expedia.co.uk/Greenville.dx1388) - [Patewood Memorial Hospital](https://www.expedia.co.uk/Patewood-Memorial-Hospital-Greenville.d6130783.Attraction) - [Simpsonville Holidays](https://www.expedia.co.uk/Simpsonville.d6239.Holidays-City-Breaks) - [Warehouse Theatre](https://www.expedia.co.uk/Warehouse-Theatre-Greenville-Downtown.d553248621532656721.Attraction) - [Alamo Rent A Car Rental Cars in Greenville](https://www.expedia.co.uk/Alamo-Rent-A-Car-Car-Rentals-In-Greenville.d1388-c6.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Greenville](https://www.expedia.co.uk/Avis-Car-Rentals-In-Greenville.d1388-c41.Car-Rental-Guide-Suppliers) - [Car hire Greenville](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Greenville.d1388.Car-Hire-Guide) - [Car hire Simpsonville](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Simpsonville.d6239.Car-Hire-Guide) - [Enterprise Rental Cars in Greenville](https://www.expedia.co.uk/Enterprise-Car-Rentals-In-Greenville.d1388-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Greenville](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Greenville.d1388-c40.Car-Rental-Guide-Suppliers) - [Luxury Car Hire in Greenville](https://www.expedia.co.uk/Luxury-Car-Rentals-In-Greenville.d1388-tLuxury.Car-Rental-Guide-Class) - [Gantt Holiday Rentals](https://www.expedia.co.uk/Gantt-Holiday-Rentals.d553248634999376437.Travel-Guide-HolidayRentals) - [Greenville Holiday Rentals](https://www.expedia.co.uk/Greenville-Holiday-Rentals.d1388.Travel-Guide-HolidayRentals) - [Mauldin Holiday Rentals](https://www.expedia.co.uk/Mauldin-Holiday-Rentals.d183944.Travel-Guide-HolidayRentals) - [Things to do in Greenville](https://www.expedia.co.uk/Things-To-Do-In-Greenville.d1388.Travel-Guide-Activities) - [Things to do in Simpsonville](https://www.expedia.co.uk/Things-To-Do-In-Simpsonville.d6239.Travel-Guide-Activities) - [Book La Quinta Inn & Suites in Upstate South Carolina on Expedia.com](https://www.expedia.com/Upstate-South-Carolina-Hotels-La-Quinta-Inn-Suites.0-0-d6057939--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)