Title: The Best Hotels in South Main, Houston - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in Houston](https://expedia.co.uk/Houston-Holiday-Rentals.d178265.Travel-Guide-HolidayRentals)[Flights to Houston](https://expedia.co.uk/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.co.uk/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[South Main Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Main.d553248635976386992.Car-Hire-Guide)[South Main Holidays](https://expedia.co.uk/South-Main.d553248635976386992.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/1503/2eeb9f80-ebf6-42ad-9574-1d77038420db.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/1503/2eeb9f80-ebf6-42ad-9574-1d77038420db.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [21 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976386992&startDate=2026-03-21&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Mar - 23 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976386992&startDate=2026-03-22&endDate=2026-03-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976386992&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976386992&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for South Main hotels ![Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/99a71929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 6:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/e04a9b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/63833027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/83265e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston near NRG Park/Medical Center [](https://www.expedia.co.uk/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) South Main 7.0/10 Good (1,251 reviews) "Property was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judson £83 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) ![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/3aca26b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/d2464018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/d9fe05fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/ba5d9607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Houston near Medical Center- NRG Stadium [](https://www.expedia.co.uk/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information) South Main 8.6/10 Excellent (1,000 reviews) "Great location if you’re headed to NRG, room was very clean. Good for an overnight " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daisy £86 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/168bdeac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/14da1a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/b0f701b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/2693cb6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Houston Medical Center by IHG [](https://www.expedia.co.uk/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information) South Main 7.4/10 Good (842 reviews) "Room was clean. It had a musty smell though. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ryan £81 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/eca4a935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/6b2e094a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/dec1e7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/d00107cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate Houston near NRG Park/Medical Center [](https://www.expedia.co.uk/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) South Main 6.6/10 (1,004 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy £69 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) ![Hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/2ae57d48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/258cd217.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/23f0ff28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/63621dad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites NRG Park - Medical Center [](https://www.expedia.co.uk/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information) South Main 6.6/10 (1,006 reviews) "Courteous staff, clean room, quite property" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier £57 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/122000000/121340000/121330700/121330601/c04d8428.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-parking](https://images.trvl-media.com/lodging/122000000/121340000/121330700/121330601/95726c8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/122000000/121340000/121330700/121330601/db3915f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/122000000/121340000/121330700/121330601/c40792da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Royale [](https://www.expedia.co.uk/Houston-Hotels-Hotel-Royale.h121330601.Hotel-Information) 13 mi from South Main 9.2/10 Wonderful (17 reviews) "Hotel is new and clean. Linens and trash were taken care of daily. Close to plenty of food options. Would stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Antonette £66 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hotel-Royale.h121330601.Hotel-Information) ![Luxury Room, 1 King Bed, Hot Tub | Desk, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/102000000/101210000/101203300/101203252/b5392b0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/102000000/101210000/101203300/101203252/6ec98869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Kitchen | Private kitchen | Coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/102000000/101210000/101203300/101203252/f8a22a91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/102000000/101210000/101203300/101203252/df3e4437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palace Inn Blue Edgebrook [](https://www.expedia.co.uk/Houston-Hotels-Palace-Inn-Edgebrook.h101203252.Hotel-Information) 10.4 mi from South Main 9.4/10 Exceptional (159 reviews) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bella £81 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/Houston-Hotels-Palace-Inn-Edgebrook.h101203252.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/23d019da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible, Kitchenette | Desk, laptop workspace, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/20cc111f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Kitchenette | Desk, laptop workspace, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/f6dc1d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115560000/115550700/115550694/w5760h3835x0y5-d6cf0bc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Pearland/Houston Medical Center Hotel [](https://www.expedia.co.uk/Houston-Hotels-Best-Western-Plus-PearlandHouston-Medical-Center-Hotel.h115550694.Hotel-Information) Southeast Houston, 6.4 mi from South Main 9.2/10 Wonderful (179 reviews) "Yes very great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lloyd £78 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Houston-Hotels-Best-Western-Plus-PearlandHouston-Medical-Center-Hotel.h115550694.Hotel-Information) ![Deluxe Single Room | Premium bedding, memory-foam beds, desk, laptop workspace](https://images.trvl-media.com/lodging/119000000/118960000/118953800/118953774/7ac8e629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/119000000/118960000/118953800/118953774/c87c3750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, stovetop](https://images.trvl-media.com/lodging/119000000/118960000/118953800/118953774/20aba4b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/119000000/118960000/118953800/118953774/2f9835ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crystal Inn - NorthWest - 290 [](https://www.expedia.co.uk/Houston-Hotels-Crystal-Inn-Northwest-290.h118953774.Hotel-Information) 15.4 mi from South Main 9.8/10 Exceptional (40 reviews) "The best hotel I’ve been in excellent rooms perfect customer service rooms are phenomenal" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £92 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Houston-Hotels-Crystal-Inn-Northwest-290.h118953774.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2950000/2947700/2947665/cb23644d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2950000/2947700/2947665/8fc78f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2950000/2947700/2947665/999ea0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2950000/2947700/2947665/d3d99628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites - Houston Space Center by IHG [](https://www.expedia.co.uk/Houston-Hotels-Holiday-Inn-Express-Hotel-Suites-Houston-Space-Center.h2947665.Hotel-Information) 19.1 mi from South Main 9.0/10 Wonderful (1,003 reviews) "Hotel is near the mall and super clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isaiah £78 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Houston-Hotels-Holiday-Inn-Express-Hotel-Suites-Houston-Space-Center.h2947665.Hotel-Information) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/2eb6fd4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/c643ab34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/de58e552.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/6d4b85c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Houston Hobby Airport [](https://www.expedia.co.uk/Houston-Hotels-Doubletree-By-Hilton-Houston-Hobby-Airport.h5886.Hotel-Information) Southeast Houston, 9 mi from South Main 8.8/10 Excellent (1,001 reviews) "Great food at the bar. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Markus £94 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Doubletree-By-Hilton-Houston-Hobby-Airport.h5886.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/10000/900/809/72a26fde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/809/155edea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/809/aa98f077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/809/d8b67d1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston North [](https://www.expedia.co.uk/Houston-Hotels-Hilton-Houston-North.h809.Hotel-Information) 19 mi from South Main 8.2/10 Very good (1,000 reviews) "Very convenient location, clean, and staff was exceptional " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shatoria £99 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hilton-Houston-North.h809.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/414e86df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Accessible, Non Smoking | Iron/ironing board, free cots/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/32c69422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/379e6bf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/dea49ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Houston-Bush Intercontinental Aprt [](https://www.expedia.co.uk/Houston-Hotels-Hampton-Inn-Suites-Houston-Bush-Intercontinental-Airport.h1558836.Hotel-Information) 19.7 mi from South Main 8.8/10 Excellent (1,805 reviews) "Nice places to stay while waiting for our next flight" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Patricia £83 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hampton-Inn-Suites-Houston-Bush-Intercontinental-Airport.h1558836.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/66da1da6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/d7eb1518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/d46bbef9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/ba58a987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Houston Intercontinental Airport [](https://www.expedia.co.uk/Houston-Hotels-Courtyard-By-Marriott-Houston-Intercontinental-Airport.h19716268.Hotel-Information) 19.8 mi from South Main 9.0/10 Wonderful (1,181 reviews) "Enjoyed my stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chelsea Renee £104 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Courtyard-By-Marriott-Houston-Intercontinental-Airport.h19716268.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/88ce8c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/b5ee10d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/a403ab12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/2b2d8506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Houston Webster NASA [](https://www.expedia.co.uk/Houston-Hotels-Tru-By-Hilton-Houston-Webster-NASA.h27293821.Hotel-Information) 19.1 mi from South Main 9.0/10 Wonderful (1,000 reviews) "Clean room, comfortable feeling, great staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £71 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Houston-Hotels-Tru-By-Hilton-Houston-Webster-NASA.h27293821.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/91000000/90620000/90610800/90610782/70356f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/91000000/90620000/90610800/90610782/78d368ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/91000000/90620000/90610800/90610782/92a37ac8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/91000000/90620000/90610800/90610782/fd82b197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moxy Houston Downtown [](https://www.expedia.co.uk/Houston-Hotels-Moxy-Houston-Downtown.h90610782.Hotel-Information) Downtown Houston, 7 mi from South Main 8.8/10 Excellent (830 reviews) "Great location wonderful staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lakira £88 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Houston-Hotels-Moxy-Houston-Downtown.h90610782.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803627/0f35fe96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803627/0bf939fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803627/251ff6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803627/e6f9d919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Manvel Inn & Suites [](https://www.expedia.co.uk/Houston-Hotels-Best-Western-Plus-Manvel-Inn-Suites.h2803627.Hotel-Information) 14.1 mi from South Main 8.8/10 Excellent (768 reviews) "This location has a gym, hot tub, and pool. The staff are all very courteous and helpful. The room was exceptionally clean and comfortable. I will definitely visit this location again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £67 includes taxes & fees 14 Apr - 15 Apr [](https://www.expedia.co.uk/Houston-Hotels-Best-Western-Plus-Manvel-Inn-Suites.h2803627.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/69d373fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/112034c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/1da2c869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/8f9922e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Houston Intercontinental Arprt [](https://www.expedia.co.uk/Houston-Hotels-SpringHill-Suites-By-Marriott-Houston-Intercontinental-Arprt.h2964240.Hotel-Information) 19.8 mi from South Main 9.0/10 Wonderful (1,688 reviews) "wonderful stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stepfan £96 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Houston-Hotels-SpringHill-Suites-By-Marriott-Houston-Intercontinental-Arprt.h2964240.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/1eac58c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/4382ed41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking (1 King Bed) | Pillow-top beds, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/74c0e598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/8055f36e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South [](https://www.expedia.co.uk/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) 19.4 mi from South Main 8.2/10 Very good (1,677 reviews) "The staff was very helpful and made our stay enjoyable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cynthia £75 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ![Deluxe Single Room | Egyptian cotton sheets, premium bedding, pillow-top beds, desk](https://images.trvl-media.com/lodging/67000000/66130000/66121500/66121415/f9cecbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio | Egyptian cotton sheets, premium bedding, pillow-top beds, desk](https://images.trvl-media.com/lodging/67000000/66130000/66121500/66121415/01b111fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/67000000/66130000/66121500/66121415/ff532cda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/67000000/66130000/66121500/66121415/56c13400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palace Inn Blue Houston East Beltway 8 [](https://www.expedia.co.uk/Houston-Hotels-Palace-Inn-Blue.h66121415.Hotel-Information) Northeast Houston, 18.3 mi from South Main 9.0/10 Wonderful (377 reviews) "Second time staying at this hotel, very friendly staff and clean rooms. Close to the highway, restaurants and movie theater. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KENDRA £60 includes taxes & fees 24 Mar - 25 Mar [](https://www.expedia.co.uk/Houston-Hotels-Palace-Inn-Blue.h66121415.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-04&endDate=2026-04-05®ionId=553248635976386992&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels in South Main | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/3aca26b9.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Comfort Suites Houston near Medical Center- NRG Stadium | 2.5 star property | 8.6Excellent1,000 reviews | View | | | | | | | ![Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/99a71929.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Wyndham Houston near NRG Park/Medical Center | 3.5 star property | 7.0Good1,251 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/eca4a935.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Wingate Houston near NRG Park/Medical Center | 3.0 star property | 6.61,004 reviews | View | | | | | | | ![Hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/2ae57d48.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Quality Inn & Suites NRG Park - Medical Center | 2.5 star property | 6.61,006 reviews | View | | | | | | | ![Room](https://images.trvl-media.com/lodging/67000000/66560000/66554500/66554439/b935cb64.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Comfort Suites Near Texas Medical Center - NRG Stadium | 2.0 star property | 9.0Wonderful6 reviews | View | | | | | | ## Where to stay in South Main Find the best South Main areas for the activities you enjoy most. - Downtown Houston - The Galleria - Texas Medical Center - Montrose - Houston Central Business District ![Discovery Green featuring a high-rise building, a city and modern architecture](https://images.trvl-media.com/place/6082195/049c767c-aaa6-4a9c-ab7c-f4f17738afe2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Discovery Green showing modern architecture, a statue or sculpture and a high-rise building](https://images.trvl-media.com/place/6082195/6ee9c9ee-bc48-42bc-9c01-25b7163f2747.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Downtown Houston](https://images.trvl-media.com/place/800037/395bdab2-12a2-4f67-b5a2-0b8cee2c2c25.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Discovery Green featuring a lake or waterhole, a city and general coastal views](https://images.trvl-media.com/place/6082195/4bd45ef8-0041-4650-831a-e7478d133781.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Downtown City skyline, Houston, Texas](https://images.trvl-media.com/place/800037/5bc4f60e-a044-46f6-9a66-5479f226f969.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=800037) ![Downtown Houston map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:s%7CrtDz%7BbeQiQ_%40eEcBgCkDuQ%7D_%40m%5EeQ%7EMi%5DoAePiLi%60%40m%40%7DTlCsl%40pNj%5CxWzUxS%60Bv%7CAhmAcg%40ncAuI%60DmZx%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=WgKNf3zxiTWREKGzy8I1t3uy5Hs=) ### Downtown Houston Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=800037) ![](https://images.trvl-media.com/place/1503/0217fd49-897c-449e-859a-75246b8b4bf4.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Man at the famous Water Wall in Houston, Texas USA](https://images.trvl-media.com/place/501263/0678cf84-c367-4c94-a162-d3e16a0367a7.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://images.trvl-media.com/place/1503/74063676-d386-4e8f-903b-ba92036d4671.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![335625583](https://images.trvl-media.com/place/501263/827e0b96-1ecf-46c5-8ef9-bfafad9f20c8.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![This place is just fun. It's a wall. There's water. A water wall. Simply put. But a great photographic opportunity awaits you here. :)](https://images.trvl-media.com/place/501263/437bb5de-d0f8-44fe-9b46-a3423f90d658.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Ryan Coleman [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=501263) ![The Galleria map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7DxptDn%7DteQ_AcXqKr%40mHsB%7BXT%5DgYeZY%3F%7D%60%40jGi%40rA_HxCyFTuIpzAsBbBt%7D%40fw%40%60NdA%7Ce%40szAdB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5e77b0krOIeDwBK5_jkO84swezY=) ### The Galleria Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=501263) ![Houston_TexasChildrensHospital_553248635389801905_9](https://images.trvl-media.com/place/553248635389801905/db4dee74-4310-41e3-8220-625d7fc800e9.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Aerial view of Herman Park near Medical center in downtown Houston, Texas](https://images.trvl-media.com/place/6143504/24718cb1-d944-454b-b1a9-0c611d76d414.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![hospitals in Texas Medical Center (world's largest medical center) treat 5 million patients annually in Houston, Texas, USA](https://images.trvl-media.com/place/6143504/2194e278-8ccf-4490-998a-b81db8545ca5.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Aerial view of Hermann park in Houston with Japanese Garden, zoo](https://images.trvl-media.com/place/6143504/f45257e8-ab2c-4d2e-9332-ef0898a9cb17.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![A panoramic view of Houston looking north towards downtown from the Medical Center](https://images.trvl-media.com/place/6143504/c73ed1e7-7fb9-4043-bf7a-2bc432a181fe.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6143504) ![Texas Medical Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wbftD%7C%60keQyBu%40u%5DkXgZySqC%7EG%7DEnG%7DQrDyAw%60%40aa%40gYrCsKe%5BcW%7CM_UbGi%40%60LmLjQmE%5DmPvB%60%40vEoQhGyJnDgKjKlC%7DDbTqAUq%40lDrYtHbGdd%40nKsDlOe%40bW%60Oj%40d_%40%7BFd%40%3FdRmCpA%3FdAtC%7CDL%60_%40eF%3F%7B%40uFiDf%40AqAwBB%7BC%60Ae%40yCm%40OlBhOjId%60%40hAnC&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=-txg4h32BKxrIPBjQzTWKWRnz0I=) ### Texas Medical Center Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6143504) ![Menil Collection featuring interior views](https://images.trvl-media.com/place/501254/bff0be25-5004-4dd7-b091-e3184d4d7f12.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Menil Collection featuring a park](https://images.trvl-media.com/place/501254/2e965ee3-7128-42cc-9c18-1f8ee066e9f4.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Outside of the Rothko Chapel is this sculpture, Broken Obelisk, and a reflection pool dedicated to Dr. Martin Luther King Jr.](https://images.trvl-media.com/place/1503/3d060ea0-9c57-4b5f-bd73-84e2bff8169b.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Andre Bosch ![Menil Collection which includes interior views](https://images.trvl-media.com/place/501254/4c3a6826-4792-4ff6-ba26-be27d8706a5e.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Menil Collection which includes art and interior views](https://images.trvl-media.com/place/501254/7707889a-989d-4895-ac5c-70a3b84145a6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=3000663145) ![Montrose map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wiptDf%7CieQmBWy%7E%40R%7BAe%40qByG_CiCwQJiG%60%40X%7BBoAyGIeOwDsLe%40qDh%40uJ%7D%40sCSsDuCkJJyE%60AsGLaMnD%7DQBcLreAQGwItTKI_MvFAb%40a%40rNdApW%40nf%40l%5D%60BlBnFpdBf%40tTElUyoA%5C&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=FA9GMjOoslAVD7SwHDyMnspJbfU=) ### Montrose Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=3000663145) ![Taken in front of apartments. #UrbanJungle](https://images.trvl-media.com/place/1503/b1e32f8c-3377-4c55-8c1f-1f9a80624bb0.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by George Zimzores ![Clear day! ](https://images.trvl-media.com/place/1503/227b8013-3274-4731-8a5d-74b65b80b557.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by George Zimzores ![Colorful City Hall! #StunningStructures ](https://images.trvl-media.com/place/1503/9d5606a3-0766-4416-8505-23e00c107526.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by George Zimzores ![Colorful City Hall! #StunningStructures ](https://images.trvl-media.com/place/1503/cd4f4b25-4a7b-4c1f-b2aa-61bab18a9737.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by George Zimzores ![Discovery Green featuring a garden, a city and a skyscraper](https://images.trvl-media.com/place/6082195/57060e4c-1ad9-4377-ba47-d89adc8382eb.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976473213) ![Houston Central Business District map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wfqtD%7EuceQsXeRk%60Ayr%40x%7E%40_jBp%7D%40zp%40qMrVh%5BfUcp%40fqA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=l24t0KYtEnk7l4YWZTxkpNv3bu8=) ### Houston Central Business District If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976473213) ## Top South Main Hotel Reviews ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/109ddc6c_y.jpg) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 10/10 Excellent "Clean room, parking was a bit expensive and the pass that was given did not work " [](https://expedia.co.uk/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/5506d9bf_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "Good stay" [](https://expedia.co.uk/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Holiday Inn Houston Downtown by IHG](https://images.trvl-media.com/lodging/9000000/8170000/8168200/8168134/50a1a294_y.jpg) ### Holiday Inn Houston Downtown by IHG 10/10 Excellent "Traveled with my spouse. It was a 10 minute walk to the Toyota Center. Hotel was very clean. " [](https://expedia.co.uk/Houston-Hotels-Holiday-Inn-Houston-Downtown.h8168134.Hotel-Information) ![Wyndham Houston near NRG Park/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/99a71929_y.jpg) ### Wyndham Houston near NRG Park/Medical Center 8/10 Good "Need more people working " [](https://expedia.co.uk/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) ![Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/70000/64200/64160/4623efea_y.jpg) ### Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham 8/10 Good "We liked the convenient location and loved the hot breakfast options like eggs, biscuits and gravy, sausage, and pancakes. The pool was open but cold since it's partially outdoors and partially covered. The hot tub was nice. Appreciated the exercise facility. Our first room smelled like weed and we were able to change right away to another one. There were some guests smoking it in the parking lot even though the hotel claims to be 100% smoke free. Overall had a great stay." [](https://expedia.co.uk/Houston-Hotels-Heritage-Inn-Suites-HoustonSugar-Land.h64160.Hotel-Information) ![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/28100/28060/ab7edfb2_y.jpg) ### Crowne Plaza Houston Med Ctr-Galleria Area by IHG 8/10 Good "Good location " [](https://expedia.co.uk/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information) ![Hyatt Regency Houston West](https://images.trvl-media.com/lodging/1000000/20000/12400/12378/a637c95a_y.jpg) ### Hyatt Regency Houston West 10/10 Excellent "Beautiful property, great for business travel!" [](https://expedia.co.uk/Houston-Hotels-Hyatt-Regency-Houston-West.h12378.Hotel-Information) ![Hyatt Regency Houston/Galleria](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/9a708987_y.jpg) ### Hyatt Regency Houston/Galleria 6/10 Okay "Check I was easy. Room was dirty, bathroom had what looked to be fecal on the floor, bad odor in room, stains on floor and night stand. The cafe, asked for three coffee’s they just forgot to make the other two and walked off. So the only feature that was great was location from HLSR. " [](https://expedia.co.uk/Houston-Hotels-Hyatt-Regency-HoustonGalleria.h10620692.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/1eac58c8_y.jpg) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 2/10 Terrible "We had just checked in and there was a small roach in the bathroom. Hallway was filled with smoke. Elevator was filthy with words engraved in the walls in the elevator. Told receptionist he changed our room but when we got to the room there was gnats on the door as well as a stale old smell in the room. Cancelled stay and had to find somewhere else to stay at 1:30 a.m." [](https://expedia.co.uk/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ## Frequently asked questions ### What are the best hotels in South Main that travellers recommend? > The 3.5-star Wyndham Houston near NRG Park/Medical Center, with a 7.2 rating, is often praised by guests for its amazing staff, comfortable beds, and clean, big rooms. It also features an outdoor pool with sun loungers and is conveniently located close to NRG Astrodome (0.9 km), NRG Park (0.7 km), and NRG Arena (0.8 km). > > > The 3-star Wingate Houston near NRG Park/Medical Center is another great option. Guests frequently highlight the friendly and extremely polite staff, the free continental breakfast, and the comfortable, clean rooms. It is very close to NRG Astrodome (0.7 km), NRG Park (0.5 km), and NRG Arena (0.7 km). > > > The Quality Inn & Suites NRG Park - Medical Center is top for its excellent customer service and hospitality, along with clean rooms and a convenient location. This hotel offers free to-go breakfast and some rooms feature a balcony. It is situated near NRG Astrodome (1.0 km), NRG Park (0.8 km), and NRG Arena (0.9 km). > > > Finally, the Comfort Suites Houston near Medical Centre- NRG Stadium, with an excellent 8.6 rating, is known for its friendly and helpful staff, comfortable and clean rooms, and a great complimentary full breakfast. It also provides fitness facilities and is conveniently located near NRG Astrodome (1.0 km), NRG Park (0.8 km), and NRG Arena (1.4 km). ### What are the best family hotels in South Main? > The 3-star Wingate Houston near NRG Park/Medical Center is a great option, located just 0.5 km from NRG Park. Guests appreciate the friendly and extremely polite staff, as well as the free and good breakfast. The comfortable and clean rooms with good beds contribute to a pleasant stay, and it also features a pool for family enjoyment. > > > Another excellent choice is the 3.5-star Wyndham Houston near NRG Park/Medical Center, rated 7.2\. Situated only 0.7 km from NRG Park, this hotel offers child-friendly window design and free cribs, making it suitable for families with young children. Guests frequently mention the great and amazing staff, the superb location, and the clean, big rooms with comfortable beds. > > > The Comfort Suites Houston near Medical Centre- NRG Stadium, with an 8.6 rating, is also highly recommended. This hotel is conveniently located 0.8 km from NRG Park and features child-friendly window design. Guests consistently praise the comfortable and clean rooms, the friendly and helpful staff, and the great breakfast. ### What are the top pet-friendly hotels in South Main? > The 3-star Wingate Houston near NRG Park/Medical Center is a great option, allowing dogs and other pets. Guests frequently highlight the friendly and polite staff, the comfortable and clean rooms, and the good complimentary breakfast. It is conveniently located near NRG Park, NRG Astrodome, and NRG Arena. > > > Another excellent choice is the 3.5-star Wyndham Houston near NRG Park/Medical Center, which permits pets. This hotel, rated 7.2, is praised for its great and amazing staff, superb location, and clean, big rooms with comfortable beds. It offers free WiFi and is also close to NRG Park, NRG Astrodome, and NRG Arena. > > > The Candlewood Suites Houston Medical Center by IHG also permits pets and has a review rating of 7.4\. This hotel provides free WiFi and free self-parking. It is situated near NRG Park, NRG Astrodome, and NRG Arena. > > > Finally, the Quality Inn & Suites NRG Park - Medical Center welcomes pets. This hotel offers free breakfast, including a to-go option, free self-parking, and a complimentary area shuttle. Guests often compliment the excellent and clean rooms, the convenient location, and the excellent customer service and hospitality. It is also very close to NRG Park, NRG Astrodome, and NRG Arena. ### What are the most romantic hotels in South Main for couples? > The Quality Inn & Suites NRG Park - Medical Center offers suites that provide extra space and comfort. Guests have consistently praised the excellent and clean rooms, as well as the convenient location of the hotel. It provides complimentary breakfast and free toiletries, adding to the convenience of your stay. The hotel also offers free self-parking and a free area shuttle, making it easy to explore the surroundings. With NRG Astrodome just 1.0 km away and NRG Arena 0.9 km away, there's plenty to see and do nearby. ### What are the best hotels in South Main near NRG Park? > The 3.5-star Wyndham Houston near NRG Park/Medical Center, with a rating of 7.2, boasts a superb location, being just 0.7 km from NRG Park. Guests frequently praise the amazing staff, the clean and spacious rooms, and the comfortable beds. It also offers child-friendly window designs and free cribs, making it a great choice for those travelling with children. > > > Another highly-rated option is the 3-star Wingate Houston near NRG Park/Medical Center. While its rating is not provided, it is consistently praised for its good location, just 0.5 km from NRG Park. This hotel offers a pool, connecting rooms, and complimentary continental breakfast, which guests often describe as good. The staff are noted for being friendly and extremely polite, and the rooms are comfortable and clean. ### When is the best time to go to South Main? > These seasons offer pleasant weather, with comfortable temperatures that are ideal for exploring the area's outdoor attractions and walking around. Spring brings blooming flowers and a refreshing atmosphere, while autumn provides cooler temperatures and often clear skies, superb for enjoying the local parks and open-air markets. > > > For those planning a romantic getaway, spring is particularly lovely. The milder weather allows for leisurely strolls along the riverwalk and enjoying al fresco dining without the intense summer heat. The natural beauty of the area is at its peak, creating a beautiful backdrop for couples. > > > Families travelling with children might find autumn more appealing. The slightly cooler temperatures are more comfortable for kids, especially when visiting attractions like the local nature centres or attending outdoor festivals. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a South Main hotel booking with Expedia? ### How much is the nightly rate at a South Main hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [4 Star Hotels in Southwest Houston ](https://www.expedia.co.uk/4Star-Southwest-Houston-Hotels.s40-0-d6189441.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Southwest Houston ](https://www.expedia.co.uk/5Star-Southwest-Houston-Hotels.s50-0-d6189441.Travel-Guide-Filter-Hotels) - [5 Star Hotels in The Galleria ](https://www.expedia.co.uk/5Star-The-Galleria-Houston-Hotels.s50-n501263-0.Travel-Guide-Filter-Hotels) - [Astrodome Hotels ](https://www.expedia.co.uk/Astrodome-Houston-Hotels.0-n553248635976007975-0.Travel-Guide-Filter-Hotels) - 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