South Main Travel Guide
Houston
Visit South Main
Things to do
Houston: Space Center Houston Admission Ticket
£22
per adult
92% of travellers recommend
Houston: Guided City Tour by an Open-Top Double Decker Bus
£30
per adult
98% of travellers recommend
Houston's Official City & Mural Tour!
£30
per adult
88% of travellers recommend
Houston Buffalo Bayou Park Cistern History Tour
£11
per adult
Houston: Sloomoo Institute Entry Ticket
£26
per adult
100% of travellers recommend
Top hotels in South Main
Wyndham Houston at Reliant Park & Medical Center
8686 Kirby Drive Houston TX
The price is £108 per night from 5 Nov to 6 Nov
£108
5 Nov - 6 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, a 24-hour fitness centre and on-site spa services. Our guests praise the helpful staff and ...
Club Quarters Hotel Downtown, Houston
1085 Rusk Street Houston TX
The price is £80 per night from 8 Nov to 9 Nov
£80
8 Nov - 9 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the helpful staff ...
8.6/10 Excellent! (4,560 reviews)
"Perfect location as the bus that serves both airports is just outside, a 5 min walk to join the Tour bus for NASA. Plenty of good bars and restaurants nearby."
Reviewed on 29 Oct 2026
The Whitehall Houston
1700 Smith St Houston TX
The price is £120 per night from 29 Nov to 30 Nov
£120
29 Nov - 30 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
8.6/10 Excellent! (2,487 reviews)
"5 stars"
Reviewed on 29 Oct 2026
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
5353 Westheimer Rd Houston TX
The price is £101 per night from 28 Nov to 29 Nov
£101
28 Nov - 29 Nov
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and the clean ...
The Royal Sonesta Houston Galleria
2222 West Loop South Houston TX
The price is £113 per night from 22 Nov to 23 Nov
£113
22 Nov - 23 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
8.8/10 Excellent! (2,389 reviews)
"The room and breakfast was great but I’m early riser need coffee to wake up so I had some issues with the coffee machine broken we called few times to fix only by the last day before checking out they took care of the issue bit upsetting and we called few times the hotel shuttle that it was offered ..."
Reviewed on 29 Oct 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
The price is £68 per night from 29 Nov to 30 Nov
£68
29 Nov - 30 Nov
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
8.6/10 Excellent! (2,224 reviews)
"Great hotel. My room was very clean. Bar/restaurant on site with reasonable prices. Front staff is very friendly and very accommodating. They have a breakfast buffet for I think $16-19. Starbucks coffee on site."
Reviewed on 29 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Main
Find the best South Main areas for the activities you enjoy most.
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
