Title: South Main Travel Guide: Best of South Main, Houston Travel 2026 | Expedia.co.uk [Hotels in South Main](https://expedia.co.uk/South-Main-Houston-Hotels.0-n553248635976386992-0.Travel-Guide-Filter-Hotels)[Flights to Houston](https://expedia.co.uk/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.co.uk/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[South Main Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Main.d553248635976386992.Car-Hire-Guide)[South Main Holidays](https://expedia.co.uk/South-Main.d553248635976386992.Holidays-City-Breaks) # South Main Travel Guide ## Houston ![Aerial view of Hermann park in Houston with Japanese Garden, zoo, Space Adventure playground](https://images.trvl-media.com/place/553248635976386992/633bd53d-8369-45ed-9507-93d6ecf02186.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Aerial view of Hermann park in Houston with Japanese Garden, zoo, Space Adventure playground](https://images.trvl-media.com/place/553248635976386992/633bd53d-8369-45ed-9507-93d6ecf02186.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![South Main](https://images.trvl-media.com/place/1503/2eeb9f80-ebf6-42ad-9574-1d77038420db.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit South Main Things to do Hotels Where to stay [Houston travel guide](https://expedia.co.uk/Houston.dx178265) --- ### Popular places to visit ![Texans Vs Bears ](https://images.trvl-media.com/place/1503/e9e0c365-cf4d-4e4b-b714-f9dd65c34baf.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### NRG Stadium Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area. [](https://expedia.co.uk/NRG-Stadium-Astrodome.d553248635929331916.Attraction) ![NFL Experience](https://images.trvl-media.com/place/1503/79f85336-9389-4f19-a086-bdba1925534e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### George R. Brown Convention Center During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the great live music and acclaimed art galleries in this vibrant area. [](https://expedia.co.uk/George-R-Brown-Convention-Center-Downtown-Houston.d501247.Attraction) ![www.alamy.com](https://images.trvl-media.com/place/501253/9f806038-e019-4ef0-8e59-8c564c0cb29c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### NASA Johnson Space Center After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event. [](https://expedia.co.uk/NASA-Johnson-Space-Center-Nassau-Bay.d501253.Attraction) ![Houston_MinuteMaidPark_6034772_1](https://images.trvl-media.com/place/6034772/6d7d1cbe-28b6-4078-86cd-2bb274c4f722.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Daikin Park Catch an event at Daikin Park during your trip to Houston. Experience the lively festivals and acclaimed theatre scene in this vibrant area. [](https://expedia.co.uk/Minute-Maid-Park-Houston.d6034772.Attraction) ![At the main entrance.](https://images.trvl-media.com/place/1503/00b4e1ca-e78a-46ba-93de-a793739a6117.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Toyota Center Catch an event at Toyota Center during your trip to Houston. Experience the entertainment choices and acclaimed art galleries in this vibrant area. [](https://expedia.co.uk/Toyota-Center-Downtown-Houston.d6082241.Attraction) ![Space Center Houston which includes interior views](https://images.trvl-media.com/place/6163111/0a492b74-6d09-47ca-8bcb-439f43fd5709.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Space Center Houston This iconic “mission control” was immortalized for its role in the first moon landing. [](https://expedia.co.uk/Space-Center-Houston-Nassau-Bay.d6163111.Attraction) ### Things to do ![The Official Houston City Tour](https://mediaim.expedia.com/localexpert/1341307/9a4763b5-bf47-4baf-83ab-9ef099515a0d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### NASA's Space Center Admission Plus Houston City Tour £80 per adult **92%** of travellers recommend [](https://expedia.co.uk/things-to-do/nasas-space-center-admission-plus-houston-city-tour.a1341307.activity-details) ![Houston: Houston Botanic Garden Entry Ticket](https://mediaim.expedia.com/localexpert/46150646/bfc34474-c86f-4151-a485-5cc63efe2aab.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston: Houston Botanic Garden Entry Ticket £9 per adult **80%** of travellers recommend [](https://expedia.co.uk/things-to-do/houston-houston-botanic-garden-entry-ticket.a46150646.activity-details) ![Astroville Tunnel Tour of Downtown Houston](https://mediaim.expedia.com/localexpert/1358845/93d97319-081a-4fec-9e57-9de4737dfee7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Astroville Tunnel Tour of Downtown Houston (Air-Conditioned) £18 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/astroville-tunnel-tour-of-downtown-houston-air-conditioned.a1358845.activity-details) ![Houston Museum of Natural Science: Cockrell Butterfly Center](https://mediaim.expedia.com/localexpert/44625315/13581a0d-ea47-46d7-8fcf-d3fc7aa4909c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Museum of Natural Science: Butterfly Center Ticket £11 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/houston-museum-of-natural-science-butterfly-center-ticket.a44625315.activity-details) ![Houston: Sloomoo Institute Entry Ticket](https://mediaim.expedia.com/localexpert/48181877/0194cadc-0356-4ecd-a787-6fed90663fc8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston: Sloomoo Institute Entry Ticket £24 per adult [](https://expedia.co.uk/things-to-do/houston-sloomoo-institute-entry-ticket.a48181877.activity-details) ![Houston: Holocaust Museum Houston Entry Ticket](https://mediaim.expedia.com/localexpert/47985204/cc6c178c-7c2f-47f0-8536-736f4d600e99.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston: Holocaust Museum Houston Entry Ticket £16 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/houston-holocaust-museum-houston-entry-ticket.a47985204.activity-details) [See all activities in Houston](https://expedia.co.uk/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities) --- ## Top hotels in South Main ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 5353 Westheimer Rd Houston TX £107 9 Mar - 10 Mar includes taxes & fees Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and the clean ... 8.2/10 Very Good! (3,337 reviews) Cleanliness Reviewed on 4 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F03%2F2026&endDate=10%2F03%2F2026&selected=20116&PinnedHotelID=20116&HadPinnedHotel=true®ionId=553248635976386992) ![Blossom Hotel Houston, Curio Collection by Hilton](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/db7ae93f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Blossom Hotel Houston, Curio Collection by Hilton 7118 Bertner Ave Houston TX £160 16 Feb - 17 Feb includes taxes & fees Stay at this spa hotel in Houston. Enjoy free Wi-Fi, a full-service spa and 2 bars/lounges. Our guests praise the pool and the helpful staff in their reviews. ... 9/10 Wonderful! (3,722 reviews) Great hotel! Reviewed on 7 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=16%2F02%2F2026&endDate=17%2F02%2F2026&selected=58985846&PinnedHotelID=58985846&HadPinnedHotel=true®ionId=553248635976386992) ![The Whitehall Houston](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Whitehall Houston 1700 Smith St Houston TX £123 15 Feb - 16 Feb includes taxes & fees Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ... 8.4/10 Very Good! (1,994 reviews) Staff was very welcoming and nice! My experience was lovely and I enjoyed a great view of outside! Everything I needed I had there, very organized. Reviewed on 1 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=15%2F02%2F2026&endDate=16%2F02%2F2026&selected=693655&PinnedHotelID=693655&HadPinnedHotel=true®ionId=553248635976386992) ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 15510 JFK Blvd Houston TX £61 9 Feb - 10 Feb includes taxes & fees Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ... 8.2/10 Very Good! (1,448 reviews) Very quiet Reviewed on 6 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F02%2F2026&endDate=10%2F02%2F2026&selected=165562&PinnedHotelID=165562&HadPinnedHotel=true®ionId=553248635976386992) ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Royal Sonesta Houston Galleria 2222 West Loop South Houston TX £115 13 Feb - 14 Feb includes taxes & fees Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ... 8.4/10 Very Good! (1,597 reviews) Great staff extremely helpful. Would love to stay there again. Reviewed on 4 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=878652&PinnedHotelID=878652&HadPinnedHotel=true®ionId=553248635976386992) ![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Club Quarters Hotel Downtown, Houston 1085 Rusk Street Houston TX £83 12 Feb - 13 Feb includes taxes & fees Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the helpful staff ... 8.4/10 Very Good! (4,057 reviews) Great staff! Only issue was the slow elevator Reviewed on 2 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=12%2F02%2F2026&endDate=13%2F02%2F2026&selected=1156923&PinnedHotelID=1156923&HadPinnedHotel=true®ionId=553248635976386992) [See all 6,614 properties in South Main](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=09%2F02%2F2026&endDate=10%2F02%2F2026®ionId=553248635976386992) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check South Main hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=2026-02-08&endDate=2026-02-09)[8 Feb - 9 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=2026-02-08&endDate=2026-02-09) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=2026-02-09&endDate=2026-02-10)[9 Feb - 10 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=2026-02-09&endDate=2026-02-10) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386992&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) --- ### Other neighbourhoods around South Main ![Whether or not you're a little bit country, Rodeo Houston is a BLAST!! Each spring you're able to grab some great BBQ, catch some live country music acts, and check out the good looking cowboys riding for 8 seconds of fame!! A Texas MUST DO!](https://images.trvl-media.com/place/1503/18186f36-2267-4279-b375-1bb94762cced.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Astrodome 4/5(1 area review) While you're in Astrodome, take in top sights like NRG Stadium or NRG Arena, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station. [](https://expedia.co.uk/Houston-Astrodome.dx553248635976007975) ![Aerial view of Herman Park near Medical center in downtown Houston, Texas](https://images.trvl-media.com/place/6143504/24718cb1-d944-454b-b1a9-0c611d76d414.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Texas Medical Center Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city. [](https://expedia.co.uk/Houston-Texas-Medical-Center.dx6143504) ![TMC](https://images.trvl-media.com/place/1503/58fd4720-60ea-4071-96b7-0d260c453508.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Museum District Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city. [](https://expedia.co.uk/Houston-Houston-Museum-District.dx6164045) ![TMC](https://images.trvl-media.com/place/1503/58fd4720-60ea-4071-96b7-0d260c453508.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### South Central Houston 3/5(1 area review) If you're spending time in South Central Houston, check out sights like Children's Museum of Houston or Houston Natural Science Museum and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station. [](https://expedia.co.uk/Houston-South-Central-Houston.dx553248635976476176) ![EyeEm Custom Shoots Q4 2018](https://images.trvl-media.com/place/3000663145/5fc14982-6419-4f20-a21b-2dee7a209053.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Montrose Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area. [](https://expedia.co.uk/Houston-Montrose.dx3000663145) ![Historic area of Houston.](https://images.trvl-media.com/place/1503/8a1d6680-853c-4601-8634-3ddc57cd8b28.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Greater Third Ward If you're spending time in Greater Third Ward, check out sights like Carl Lewis International Track and Field Complex or Fertitta Center and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station. [](https://expedia.co.uk/Houston-Greater-Third-Ward.dx553248635976008254) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # South Main Travel Guide ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app