South Main Holidays from £821

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Your South Main Holiday

Immerse yourself in all this neighbourhood has to offer with a tailor-made South Main holiday package. However you picture yourself spending your days here, you'll find endless opportunities for fun, adventure and relaxation. When it's time to explore the sights, you'll find loads of popular attractions nearby including NRG Stadium, NRG Park and Main Street Theatre - Rice Village. Visit one, two or all during your trip to South Main. No matter what your dream South Main holiday looks like, you can make it a reality with Expedia.

Price found within the past 48 hours. Click for updated prices.
Tx Home Group- Houston

Tx Home Group- Houston

Northside
£821
per person
21 Oct - 28 Oct
found 1 hour ago
Return direct flight included
London (LON) to Houston (IAH)
No reviews
Experience a First Class Stay - 2 BDRM

Experience a First Class Stay - 2 BDRM

£1,026
per person
21 Oct - 28 Oct
found 1 hour ago
Return direct flight included
London (LON) to Houston (IAH)
8/10 Very good! (5 reviews)
This people have water that smells like poop. Sewage water is what they use for water. Remnants of trash, sticky nastiness in drawers, air vents falling off ceilings. Random kids belts found? Candy stuck to floor? Trash wasn’t even taken out. Mind you I have kids that found these things as well. Oh and don’t even try and ask for them to refund you for their disgusting rental. They will give you the run around and then IGNORE YOU. Awful establishment and these people NEED TO BE SHUTDOWN.

Reviewed on 11 Mar 2022

Landing Apartments Humble near Bordersville

Landing Apartments Humble near Bordersville

£981
per person
21 Oct - 28 Oct
found 1 hour ago
Return direct flight included
London (LON) to Houston (IAH)
No reviews
Staybridge Suites Houston - Humble Beltway 8 E by IHG

Staybridge Suites Houston - Humble Beltway 8 E by IHG

£893
per person
21 Oct - 28 Oct
found 1 hour ago
Return direct flight included
London (LON) to Houston (IAH)
9.4/10 Exceptional! (403 reviews)
Looks brand new, clean, very friendly staff.

Reviewed on 3 Sept 2026

Houston Marriott North

Houston Marriott North

Northside
£915
per person
21 Oct - 28 Oct
found 1 hour ago
Return direct flight included
London (LON) to Houston (IAH)
8.4/10 Very good! (1,007 reviews)

Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most. Learn more about South Main
A city square with tall buildings, trees, and green lights.

Downtown Houston

3 out of top 10 points of interest in this area

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

Find hotels in Downtown Houston
A person walking in front of a building with a brick facade and three arched windows.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.

Find hotels in The Galleria
A cityscape with a park, a river, and a large building with a red roof.

Texas Medical Center

1 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Find hotels in Texas Medical Center
A colorful mural on a building, a street with outdoor seating, and a van parked on the side.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area.

Find hotels in Montrose
A cityscape with modern skyscrapers and a parking lot filled with cars.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Find hotels in Houston Central Business District

Top hotels in South Main

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
£99
11 Sept - 12 Sept
includes taxes & fees
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
£222
6 Sept - 7 Sept
includes taxes & fees
9.2/10 Wonderful! (1,001 reviews)
"My stay was exceptional well! Will return."

Reviewed on 3 Sept 2026

Hotel Zaza Houston Museum District
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
£76
7 Sept - 8 Sept
includes taxes & fees
Club Quarters Hotel Downtown, Houston
See all 7,430 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays
Golf Holidays
Golf Holidays
Luxury Holidays
Luxury Holidays
gay friendly holidays
LGBTQ+ Holidays
LGBTQ+ Holidays
Romantic Holidays
Romantic Holidays
Ski Holidays
Ski Holidays
Pet Friendly Holidays
Pet Friendly Holidays
Holiday in Month
Where to go when
Where to go when

Frequently asked questions

How much does a South Main travel package cost?
We make it simple to travel the world, with South Main travel packages starting from as low as £821. You'll have the flexibility to bundle your favourite hotels, airlines and car rental. For the ultimate escape, why not add a few tours and experiences to your travel itinerary?
If I'm not able to travel, can I cancel my South Main travel package?
It's difficult to predict what the future holds, so it's good to know that you can cancel or change your South Main travel package. If your booking was made in the last 24 hours, you may be eligible for a refund. If your booking is older, your hotel, airline or car rental company may charge a fee. Check our Customer Service Portal to find out more.
How do I get a cheap travel package to South Main?
Creating your own South Main travel package with Expedia is a simple way to save. We offer more than 550 airlines and 1,000,000 hotel options across the globe. With such an awesome range to pick from, you'll have no difficulty pulling together your perfect adventure.
Does Expedia offer Book Now, Pay Later South Main holidays?
Expedia has teamed up with online lender Klarna to make booking your next break easier on your wallet. Paying in instalments means you can spread the costs of your next adventure, leaving you with more cash to splash while you're travelling. Klarna has several payment plans to choose from, so you're sure to find something that fits your budget. Browse these flexible payment options:
  • Pay monthly holidays: If paying bite-sized amounts each month works for you, Klarna can help. Paying in convenient monthly instalments will make your holiday dreams possible.
  • Pay in instalments holidays: Into the idea of paying down your holiday in multiple transactions? Then go for this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: Hitting the "book now" button is much easier with this option. Just put down a small deposit on your holiday and then start working on your travel itinerary.
Where should I stay in South Main?
Urban adventurers come from all over the world to experience Johnson Space Centre - NASA and Toyota Centre in South Main. Book a room close to these wonderful attractions to make sightseeing a breeze.
What are the top hotels in South Main?
Reserve a room at Doubletree By Hilton Houston Medical Centre Hotel And Suites. It's one of the neighbourhood's most in-demand hotels. Another top-rated option in South Main is The Whitehall Houston.
How far in advance should I book my South Main holiday?
It's tricky picking the perfect time for airfares, but we normally say the earlier, the better. Many international flights on Expedia become available to compare up to a year in advance. If you're booking late, fear not. Cheap prices occasionally appear just weeks before departure dates.
What does an Expedia South Main travel package include?
It comes down to what you want. If you're travelling solo, you might decide to bundle flights and hotels. Bringing the entire family to South Main? A travel package including hotels, rental cars and flights might suit you better. Expedia gives you the freedom and flexibility to tailor-make your travel package.
What should I know before booking a South Main travel package?
An Expedia travel package can be customized for your circumstances and is a great way to make your budget go further. What you include is up to you. Rental cars, hotels and flights — choose any combination that suits your plans.
Can I choose my airline with a South Main Expedia travel package?
Most definitely. Expedia has over 550 airline partners to select from globally. With such a huge range of choice, finding the ideal carrier to whisk you away to South Main won't be hard.

Things to do

Picture 3 for Activity Houston: Space Center Houston Admission Ticket

Houston: Space Center Houston Admission Ticket

£22
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
Houston: Guided City Tour by an Open-Top Double Decker Bus

Houston: Guided City Tour by an Open-Top Double Decker Bus

£29
per adult
98% of travellers recommend
Houston: Guided City Tour by an Open-Top Double Decker Bus
HOP ON- HOP OFF

Houston's Official City & Mural Tour!

£29
per adult
88% of travellers recommend
Houston's Official City & Mural Tour!
See all activities in Houston

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.