South Main Holidays

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Your South Main Holiday

Immerse yourself in all this neighbourhood has to offer with a tailor-made South Main holiday package. However you picture yourself spending your days here, you'll find endless opportunities for fun, adventure and relaxation. When it's time to explore the sights, you'll find loads of popular attractions nearby including NRG Stadium, NRG Park and Main Street Theatre - Rice Village. Visit one, two or all during your trip to South Main. No matter what your dream South Main holiday looks like, you can make it a reality with Expedia.

Price found within the past 48 hours. Click for updated prices.
  • Front of property – evening/night
    Jun 28 - Jul 7

    The Residency Suites + Flight

    Houston
    9 nights
    2.0 star property
    9.0/10 - Wonderful (242 reviews)
    Return • London (LHR) - Houston (IAH)
    LHR - IAH • 1 stop IAH - LGW • 1 stop
    £1,443
    £1,249
    per traveller
    found 1 day ago
    The Residency Suites
  • Water park
    Jul 17 - Jul 24

    The Woodlands Resort, Curio Collection by Hilton + Flight

    Panther Creek
    6 nights
    4.0 star property
    9.0/10 - Wonderful (1,008 reviews)
    "Take mor money at checkout"
    Reviewed May 27, 2026
    Return • London (LGW) - Houston (IAH)
    LGW - IAH • 1 stop IAH - LGW • 1 stop
    £1,784
    £1,495
    per traveller
    found 1 day ago
    The Woodlands Resort, Curio Collection by Hilton
  • Lobby
    Jul 17 - Jul 24

    Kompose Residences Houston Cy-Fair + Flight

    Houston
    6 nights
    3.0 star property
    9.4/10 - Exceptional (553 reviews)
    "Good"
    Reviewed May 26, 2026
    Return • London (LGW) - Houston (IAH)
    LGW - IAH • 1 stop IAH - LGW • 1 stop
    £1,459
    £1,252
    per traveller
    found 1 day ago
    Kompose Residences Houston Cy-Fair
  • Lobby
    Jul 17 - Jul 24

    Blossom Hotel Houston, Curio Collection by Hilton + Flight

    Texas Medical Center
    6 nights
    4.0 star property
    9.0/10 - Wonderful (3,845 reviews)
    "No complaints, would stay here again!"
    Reviewed May 26, 2026
    Return • London (LGW) - Houston (IAH)
    LGW - IAH • 1 stop IAH - LGW • 1 stop
    £1,544
    £1,327
    per traveller
    found 1 day ago
    Blossom Hotel Houston, Curio Collection by Hilton
  • Exterior
    Jun 28 - Jul 7

    The Moran CITYCENTRE + Flight

    Memorial
    9 nights
    4.0 star property
    9.0/10 - Wonderful (1,042 reviews)
    "The hotel is centrally located in a shopping district and steps from many restaurants and theater. It definitely suited for a family with young children with a small playground to release some energy. Another great part of this hotel since its next to parking structure for all the amenities, there are ample parkings on the second and third floor, extra savings for the goodies. The only lesser part taken of this hotel was its age has definitely showed throughout. Overall, we had a great stay."
    Reviewed May 26, 2026
    Return • London (LHR) - Houston (IAH)
    LHR - IAH • 1 stop IAH - LGW • 1 stop
    £1,811
    £1,570
    per traveller
    found 1 day ago
    The Moran CITYCENTRE

Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most. Learn more about South Main
Downtown Houston

Downtown Houston

3 out of top 10 points of interest in this area
4/5(25 area reviews)

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

Find hotels in Downtown Houston

Top hotels in South Main

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
The price is £133 per night from 7 Jun to 8 Jun
£133
7 Jun - 8 Jun
includes taxes & fees
8.4/10 Very Good! (4,078 reviews)
"The staff was excellent and perfectly attentive to any and all needs. The property is not kept up well though. The hinges on doors in the bathroom are rusted. The toilet is sized for a toddler. The amenities are very outdated. You can’t even stream on the tv’s. The towels are not adult size."

Reviewed on 26 May 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
The price is £95 per night from 31 May to 1 Jun
£95
31 May - 1 Jun
includes taxes & fees
8.6/10 Excellent! (4,185 reviews)
"Staff was great. Nice, very friendly and helpful. The room was the size of a cruise cabin. It felt so small. The view from the inside out was awful. There was just another brick wall to look at. The room had no safe, no microwave or refrigerator. There was no ice machine around. The closet and bathroom ..."

Reviewed on 24 May 2026

Club Quarters Hotel Downtown, Houston
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is £210 per night from 28 May to 29 May
£210
28 May - 29 May
includes taxes & fees
9.2/10 Wonderful! (1,016 reviews)
"All of the staff were helpful and kind. The afternoon treats in the lobby in the afternoon and butler pantry on each floor in the morning were a nice touch. Complimentary shuttle was very convenient. Enjoyed the massage and facial at the massage, but the spa itself is fairly small. Hotel itself is ..."

Reviewed on 26 May 2026

Hotel Zaza Houston Museum District
See all 7,082 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a South Main travel package cost?
We make it simple to travel the world, with South Main travel packages starting from as low as . You'll have the flexibility to bundle your favourite hotels, airlines and car rental. For the ultimate escape, why not add a few tours and experiences to your travel itinerary?
If I'm not able to travel, can I cancel my South Main travel package?
It's difficult to predict what the future holds, so it's good to know that you can cancel or change your South Main travel package. If your booking was made in the last 24 hours, you may be eligible for a refund. If your booking is older, your hotel, airline or car rental company may charge a fee. Check our Customer Service Portal to find out more.
How do I get a cheap travel package to South Main?
Creating your own South Main travel package with Expedia is a simple way to save. We offer more than 550 airlines and 1,000,000 hotel options across the globe. With such an awesome range to pick from, you'll have no difficulty pulling together your perfect adventure.
Does Expedia offer Book Now, Pay Later South Main holidays?
Expedia has teamed up with online lender Klarna to make booking your next break easier on your wallet. Paying in instalments means you can spread the costs of your next adventure, leaving you with more cash to splash while you're travelling. Klarna has several payment plans to choose from, so you're sure to find something that fits your budget. Browse these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month works for you, Klarna can help. Paying in convenient monthly instalments will make your holiday dreams possible.
  • Pay in instalments holidays: Into the idea of paying down your holiday in multiple transactions? Then go for this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: Hitting the "book now" button is much easier with this option. Just put down a small deposit on your holiday and then start working on your travel itinerary.

Where should I stay in South Main?
Urban adventurers come from all over the world to experience Johnson Space Centre - NASA and Toyota Centre in South Main. Book a room close to these wonderful attractions to make sightseeing a breeze.
What are the top hotels in South Main?
Reserve a room at Doubletree By Hilton Houston Medical Centre Hotel And Suites. It's one of the neighbourhood's most in-demand hotels. Another top-rated option in South Main is The Whitehall Houston.
How far in advance should I book my South Main holiday?
It's tricky picking the perfect time for airfares, but we normally say the earlier, the better. Many international flights on Expedia become available to compare up to a year in advance. If you're booking late, fear not. Cheap prices occasionally appear just weeks before departure dates.
What does an Expedia South Main travel package include?
It comes down to what you want. If you're travelling solo, you might decide to bundle flights and hotels. Bringing the entire family to South Main? A travel package including hotels, rental cars and flights might suit you better. Expedia gives you the freedom and flexibility to tailor-make your travel package.
What should I know before booking a South Main travel package?
An Expedia travel package can be customized for your circumstances and is a great way to make your budget go further. What you include is up to you. Rental cars, hotels and flights — choose any combination that suits your plans.
Can I choose my airline with a South Main Expedia travel package?
Most definitely. Expedia has over 550 airline partners to select from globally. With such a huge range of choice, finding the ideal carrier to whisk you away to South Main won't be hard.

Popular places to visit

NRG Stadium

NRG Stadium

5/5(5 reviews)

Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

NRG Stadium
www.alamy.com

NASA Johnson Space Center

5/5(14 reviews)

After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.

NASA Johnson Space Center
HOUSTON, TX, USA - SEPTEMBER 10, 2018: The Robert R. Brown Convention Center is a massive 1,900,000 square foot building that's located in downtown Houston that holds plenty of conferences and events.

George R. Brown Convention Center

4/5(3 reviews)

During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the acclaimed art galleries and lively festivals in this vibrant area.

George R. Brown Convention Center

Things to do

Picture 3 for Activity Houston: Space Center Houston Admission Ticket

Houston: Space Center Houston Admission Ticket

£22
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
The Official Houston City Tour

NASA's Space Center & Official Houston City Tour with tickets

£80
per adult
92% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
Astroville Tunnel Tour of Downtown Houston

Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)

£18
per adult
100% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
See all activities in Houston

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.