South Main Travel Guide

Houston

A city skyline with modern buildings and a park with a lake.
A modern urban street with a metro train, buildings, and a clear blue sky.

Things to do

Picture 3 for Activity Houston: Space Center Houston Admission Ticket

Houston: Space Center Houston Admission Ticket

£22
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
Houston: Guided City Tour by an Open-Top Double Decker Bus

Houston: Guided City Tour by an Open-Top Double Decker Bus

£30
per adult
98% of travellers recommend
Houston: Guided City Tour by an Open-Top Double Decker Bus
HOP ON- HOP OFF

Houston's Official City & Mural Tour!

£30
per adult
88% of travellers recommend
Houston's Official City & Mural Tour!
Houston Buffalo Bayou Park Cistern History Tour

Houston Buffalo Bayou Park Cistern History Tour

£11
per adult
Houston Buffalo Bayou Park Cistern History Tour
Artechouse Houston Ticket

Artechouse Houston Ticket

£22
per adult
Artechouse Houston Ticket
Houston: Sloomoo Institute Entry Ticket

Houston: Sloomoo Institute Entry Ticket

£26
per adult
100% of travellers recommend
Houston: Sloomoo Institute Entry Ticket
See all activities in Houston

Top hotels in South Main

Wyndham Houston at Reliant Park & Medical Center

Wyndham Houston at Reliant Park & Medical Center

3.5 out of 5
8686 Kirby Drive Houston TX
The price is £107 per night from 6 Nov to 7 Nov
£107
6 Nov - 7 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, a 24-hour fitness centre and on-site spa services. Our guests praise the helpful staff and ...
Wyndham Houston at Reliant Park & Medical Center
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
The price is £80 per night from 10 Nov to 11 Nov
£80
10 Nov - 11 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the helpful staff ...
Club Quarters Hotel Downtown, Houston
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
The price is £120 per night from 29 Nov to 30 Nov
£120
29 Nov - 30 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
8.6/10 Excellent! (2,474 reviews)
"5 stars"

Reviewed on 29 Oct 2026

The Whitehall Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
The price is £100 per night from 24 Nov to 25 Nov
£100
24 Nov - 25 Nov
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and the clean ...
8.4/10 Very good! (4,660 reviews)
"Great service!!"

Reviewed on 30 Oct 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
The price is £113 per night from 23 Nov to 24 Nov
£113
23 Nov - 24 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
8.8/10 Excellent! (2,391 reviews)
"Excellent service great room once area"

Reviewed on 30 Oct 2026

The Royal Sonesta Houston Galleria
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
The price is £68 per night from 29 Nov to 30 Nov
£68
29 Nov - 30 Nov
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
8.6/10 Excellent! (2,225 reviews)
"Came into town for a concert and had a great experience! Staff were very friendly and accommodating! Thank you!"

Reviewed on 30 Oct 2026

Hilton Houston Plaza/Medical Center
See all 7,528 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

A city skyline with modern skyscrapers and a river flowing through a park.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

South Main Travel Guide

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