Title: Seneca Holiday Homes from £182: Search Holiday Homes in Seneca | Expedia.co.uk [Hotels in Seneca](https://expedia.co.uk/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Holiday Rentals in Seneca](https://expedia.co.uk/Seneca-Holiday-Rentals.d6548.Travel-Guide-HolidayRentals)[Flights to Seneca](https://expedia.co.uk/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Seneca Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Seneca.d6548.Car-Hire-Guide)[Seneca Holidays](https://expedia.co.uk/Seneca.d6548.Holidays-City-Breaks) ![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6548&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [22 May - 24 May](https://www.expedia.co.uk/Hotel-Search?regionId=6548&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [19 Jun - 21 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=6548&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [17 Jul - 19 Jul](https://www.expedia.co.uk/Hotel-Search?regionId=6548&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Seneca holiday homes ![Private kitchen](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/40d3b059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/1da4db10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/ec808a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/89ea8ad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clemson Cottage - 3.6 mi. to Memorial Stadium [](https://www.expedia.co.uk/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information) Seneca 10/10 Exceptional (16 reviews) "Seriously comfortable home, the beds and pillows all fantastic, nicely appointed in every way. Can’t wait to stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £287 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/e032590e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/518d0c67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/8a811318.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/9b29fdfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell [](https://www.expedia.co.uk/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information) Seneca 10/10 Exceptional (9 reviews) "We enjoyed our stay. Had everything we needed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane S. £388 includes taxes & fees 24 Apr - 25 Apr [](https://www.expedia.co.uk/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/0834ba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/c941d493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/51bdec15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/ab96edf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock [](https://www.expedia.co.uk/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information) Seneca 8.8/10 Excellent (5 reviews) "Everything was in great condition! Items provided were good quality. You can tell a lot of time and thought has been put into this property. We would love to stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alisa W. £217 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/436516e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/345ab4fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/077dae4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/ff2ee17b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Adventures \~ Peaceful Lakefront Home on Keowee \~ 7 Miles from Clemson! [](https://www.expedia.co.uk/Seneca-Hotels-New-Peaceful-Lakefront-Home-On-Keowee-Only-7-Miles-From-Clemson.h87552049.Hotel-Information) Seneca 9.8/10 Exceptional (59 reviews) "We had a beautiful stay over Thanksgiving in this very cozy lake house. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felicia L. £449 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Seneca-Hotels-New-Peaceful-Lakefront-Home-On-Keowee-Only-7-Miles-From-Clemson.h87552049.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/825f9309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/ce0e5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, stereo](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/735219a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/644a4539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger [](https://www.expedia.co.uk/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information) Serenity Bay 9.8/10 Exceptional (130 reviews) "Beautiful home, well furnished, very clean, easy TV" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alan £534 includes taxes & fees 27 Mar - 28 Mar [](https://www.expedia.co.uk/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/9e2b77c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/d1bcfdf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/651434b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/a5e27533.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson! [](https://www.expedia.co.uk/Seneca-Hotels-Renovated-Bungalow-1-Block-From-Downtown-Seneca-8-Miles-From-Clemson.h105769612.Hotel-Information) Downtown 10/10 Exceptional (16 reviews) "Great home base for a Clemson game. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen A. £247 includes taxes & fees 1 Apr - 2 Apr [](https://www.expedia.co.uk/Seneca-Hotels-Renovated-Bungalow-1-Block-From-Downtown-Seneca-8-Miles-From-Clemson.h105769612.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/7bfcd263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/fa054611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, ping pong](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/1692b12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/bf812e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson [](https://www.expedia.co.uk/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information) Seneca 10/10 Exceptional (6 reviews) "Great place with a lot close by" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aldor D. £243 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/fc891652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/f0fe695d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/98c8974f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/d37b415d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium [](https://www.expedia.co.uk/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information) Seneca 9.6/10 Exceptional (8 reviews) "Very accommodating host. Property is a great location and very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Craig F. £513 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information) ![4 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/41018e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/3ef9dbf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, printers](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/d0ce4a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/aad65738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Johnsons Cove - Lakefront Retreat With EV Charger [](https://www.expedia.co.uk/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger.h114843702.Hotel-Information) Seneca 10/10 Exceptional (1 review) "We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca G. £562 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger.h114843702.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/106000000/105170000/105164100/105164063/967698a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105170000/105164100/105164063/5507d727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/106000000/105170000/105164100/105164063/3b0074de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105170000/105164100/105164063/6daf97b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seneca lake house with private dock only 15 minutes from Clemson! [](https://www.expedia.co.uk/Seneca-Hotels-Seneca-Lake-House-With-Private-Dock-Only-15-Minutes-From-Clemson.h105164063.Hotel-Information) Seneca 9.8/10 Exceptional (10 reviews) "We had a great time at Seneca Lake House. We would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott M. £569 includes taxes & fees 26 Mar - 27 Mar [](https://www.expedia.co.uk/Seneca-Hotels-Seneca-Lake-House-With-Private-Dock-Only-15-Minutes-From-Clemson.h105164063.Hotel-Information) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/c027128d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/84d2a4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, video games, table football](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/1ece8b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/9e13146e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Big Golf House- 10 miles to Clemson [](https://www.expedia.co.uk/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information) Seneca 10/10 Exceptional (2 reviews) "Absolutely! Perfect space for our needs, so for accommodating for our family & pet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gennifer Q. £429 includes taxes & fees 14 Apr - 15 Apr [](https://www.expedia.co.uk/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/b866198b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/3e3661cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/c09b9ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/998168ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Retreat! Swim, Boat, Kayak & Relax on Dock Just Steps from the Water [](https://www.expedia.co.uk/Seneca-Hotels-LAKE-FRONT-RETREAT-Steps-Away-From-Swimming.h37012874.Hotel-Information) Seneca 10/10 Exceptional (82 reviews) "Nice location and functionality for family. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) T P. £683 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Seneca-Hotels-LAKE-FRONT-RETREAT-Steps-Away-From-Swimming.h37012874.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/124000000/123400000/123391800/123391761/c0c7aef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123400000/123391800/123391761/47499ce9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, offices](https://images.trvl-media.com/lodging/124000000/123400000/123391800/123391761/4dfb8425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, travel cot, free WiFi](https://images.trvl-media.com/lodging/124000000/123400000/123391800/123391761/46d429c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish | Pvt Baths | Minutes to Dining & Shopping [](https://www.expedia.co.uk/Anderson-Hotels-Cozy-2-Bedroom-2-Bath-House-In-Anderson.h123391761.Hotel-Information) Anderson £228 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Anderson-Hotels-Cozy-2-Bedroom-2-Bath-House-In-Anderson.h123391761.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/23dbb562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/7d94b763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/950291d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/101000000/100340000/100330600/100330565/d43b9274.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sunny Side Cottage: Cozy Stay by Anderson U! [](https://www.expedia.co.uk/Anderson-Hotels-Charming-Bungalow-One-Block-To-Anderson-University.h100330565.Hotel-Information) Anderson 9.8/10 Exceptional (23 reviews) "Great stay, home was well stocked with all the goodies that made the stay even more enjoyable!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin K. £312 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Anderson-Hotels-Charming-Bungalow-One-Block-To-Anderson-University.h100330565.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/110000000/109020000/109017200/109017166/c7f84bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109020000/109017200/109017166/4c2d4156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/110000000/109020000/109017200/109017166/56c83409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/110000000/109020000/109017200/109017166/eb6ed59e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson|LakeAccess|ParkPass|PizzaOven|YouTubeTV|King|SUPs|EV [](https://www.expedia.co.uk/Anderson-Hotels-ClemsonMarinaParkPassPizzaOvenKayaksFirePit.h109017166.Hotel-Information) Anderson 10/10 Exceptional (9 reviews) "Stefania was more than helpful! We will definitely book with her again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna S. £410 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Anderson-Hotels-ClemsonMarinaParkPassPizzaOvenKayaksFirePit.h109017166.Hotel-Information) ![Smart TV, fireplace, books, printers](https://images.trvl-media.com/lodging/94000000/93160000/93152800/93152735/81095175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books, printers](https://images.trvl-media.com/lodging/94000000/93160000/93152800/93152735/28fd8c1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/94000000/93160000/93152800/93152735/fc8eb4fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/94000000/93160000/93152800/93152735/22d8032f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Brick House At Currahee [](https://www.expedia.co.uk/Toccoa-Hotels-The-Brick-House-At-Currahee.h93152735.Hotel-Information) Toccoa 9.8/10 Exceptional (88 reviews) "My husband and I had a great stay! The house was fantastic and great for a weekend trip! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel M. £182 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Toccoa-Hotels-The-Brick-House-At-Currahee.h93152735.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/32000000/31980000/31971400/31971354/df323d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/32000000/31980000/31971400/31971354/8359739c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31980000/31971400/31971354/fcc50872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/32000000/31980000/31971400/31971354/5530e2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakehouse Retreat with dock, paddle boat, canoe & kayaks! Now have Gas Grill [](https://www.expedia.co.uk/Anderson-Hotels-Lakehouse-Retreat-With-Dock.h31971354.Hotel-Information) Anderson 10/10 Exceptional (187 reviews) "Hot tub was awesome, could watch the deer in the backyard with your coffee in your hand. Nice dock to fish from. Spacious house, open floor plan. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy [](https://www.expedia.co.uk/Anderson-Hotels-Lakehouse-Retreat-With-Dock.h31971354.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928424/a31ec2c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928424/64f187a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928424/b904fba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113930000/113928500/113928424/8905f49d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake front with dock & covered slip on Lake Hartwell. The Reese Retreat! [](https://www.expedia.co.uk/Westminster-Hotels-Lake-Front-With-Dock-Covered-Slip-On-Lake-Hartwell-The-Reese-Retreat.h113928424.Hotel-Information) Westminster 8.6/10 Excellent (8 reviews) "Awesome lake house. Hope to stay again in the future at some point!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) steven r. £251 includes taxes & fees 26 Mar - 27 Mar [](https://www.expedia.co.uk/Westminster-Hotels-Lake-Front-With-Dock-Covered-Slip-On-Lake-Hartwell-The-Reese-Retreat.h113928424.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/b7a1f289.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/df53fc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/7411cba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/830174bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Welcome To Downtown Pickens close to Clemson and Lake Keowee [](https://www.expedia.co.uk/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information) Pickens 9.8/10 Exceptional (33 reviews) "Great location, close to great restaurants and downtown. Beautiful area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom B. £191 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/0e18a612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/33804100.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/7923d847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/121000000/120650000/120648400/120648317/b3a97246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Black Bear Hideaway [](https://www.expedia.co.uk/Pickens-Hotels-Black-Bear-Hideaway.h120648317.Hotel-Information) Pickens 9.2/10 Wonderful (5 reviews) "Great location to hiking trails." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeromy S. £199 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Pickens-Hotels-Black-Bear-Hideaway.h120648317.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08®ionId=6548&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CABIN) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VACATION_HOME) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=COTTAGE) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APARTMENT) Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APART_HOTEL) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CONDO) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VILLA) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=HOUSE_BOAT) Chalets [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Private-Holiday-Homes.d6548-aaPrivateHolidayHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Private-Holiday-Homes.d6548-aaPrivateHolidayHomes.Travel-Guide-Accommodation) ## Top Seneca Hotel Reviews ![New to VRBO! Big water views, private dock, pool table, 15 min Clemson!](https://images.trvl-media.com/lodging/58000000/57950000/57941100/57941024/eb68ea9e_y.jpg) ### New to VRBO! Big water views, private dock, pool table, 15 min Clemson! 10/10 Excellent "We enjoyed our stay at your property very much.Everything was exceptionally clean and well taken care of. Thank you for quickly addressing the issue with the heat pump." [](https://expedia.co.uk/Anderson-Hotels-NEW-TO-Vrbo-Large.h57941024.Hotel-Information) ![Inn @ Clemson](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d_y.jpg) ### Inn @ Clemson 10/10 Excellent "All of the staff we encountered were extremely nice and helpful. The beds were very comfortable thoroughly enjoyed our stay." [](https://expedia.co.uk/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90_y.jpg) ### Lakeside Lodge Clemson 10/10 Excellent "The unit was terrific. Quiet and clean. only issue is daily train whistle nearby. Nice area with grrat restaurant in hotel. " [](https://expedia.co.uk/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Loved our time here! Staff was super sweet and helpful. Room was very nice and the bed very cozy. Room felt a little small but the bathroom was larger than expected, and again all nice and clean. No complaints! Great place to stay when in the area! Love the mission to help those differently abled, as well!!" [](https://expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Best Western Seneca-Clemson](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/eaa8fc9a_y.jpg) ### Best Western Seneca-Clemson 10/10 Excellent "Clean room! Great staff! " [](https://expedia.co.uk/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "I enjoyed my stay at the BW Plus. It's super convenient (I walked home from downtown one night - not a short walk but very manageable). The property was clean, the staff was VERY friendly, the room was more than adequate (I had 2 queens and it had a desk/chair and side chair with 'breakfast tray.' The bathroom was just fine. The breakfast area is HUGE and has all you need to get started in the morning, plus they have ping pong and ample seating for groups. I have already booked stays for the fall." [](https://expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Tru by Hilton Seneca Clemson](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283_y.jpg) ### Tru by Hilton Seneca Clemson 10/10 Excellent "Clean room, friendly staff. Great place to stay!" [](https://expedia.co.uk/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Fairfield Inn & Suites Seneca Clemson Univ Area ](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5_y.jpg) ### Fairfield Inn & Suites Seneca Clemson Univ Area 10/10 Excellent "Clean room freindly staff and convenient location to stores" [](https://expedia.co.uk/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!](https://images.trvl-media.com/lodging/34000000/33730000/33728200/33728167/7de7c272_y.jpg) ### 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly! 10/10 Excellent "The home was beautiful, the amenities fantastic, and we especially enjoyed the kayaks! The kitchen was also stocked with all the basics we needed which saved us from additional grocery expense for items we would only be using for a couple of days. The owner was also a delight to work with. Wonderful experience!" [](https://expedia.co.uk/Anderson-Hotels-Beautiful-43.h33728167.Hotel-Information) ## Find out more about Seneca ## Seneca Holiday Homes information | Number of reviews | 460 | | ----------------- | ----------------- | | Accommodation | 659 Holiday Homes | | Lowest Price | £182 | | Highest Price | £683 | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Apartments in Aiken ](https://www.expedia.co.uk/Aiken-Apartments.d6058112-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in Aiken ](https://www.expedia.co.uk/Aiken-Cabins.d6058112-aaCabins.Travel-Guide-Accommodation) - [Hotels near Anderson County Regional ](https://www.expedia.co.uk/Anderson-County-Regional-Airport-Hotels.0-aAND-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Anderson ](https://www.expedia.co.uk/Anderson-Hotels-Gay-Friendly-Hotel.0-0-d6058009-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Anderson ](https://www.expedia.co.uk/Anderson-Hotels-Historic-Hotel.0-0-d6058009-tHistoricHotel.Travel-Guide-Filter-Hotels) - 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