Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Our top choices for Seneca holiday homes
1. Peaceful 3-bedroom home 4 miles from Clemson.
Peaceful 3-bedroom home 4 miles from Clemson.Seneca
10.0 out of 10, Exceptional, (1 review)
"We were very comfortable for our stay and the property was everything we expected and more."
Justin K.
The price is £203
includes taxes & fees
11 Nov - 12 Nov
2. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and ClemsonSeneca
9.8 out of 10, Exceptional, (13 reviews)
"Easy check in, pet-friendly, great location!!"
Jason M.
The price is £271
includes taxes & fees
8 Nov - 9 Nov
3. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Walk to Boat Ramp Lake Keowee w/ Parking + FirepitSeneca
6.0 out of 10, (2 reviews)
"The house was immaculate and welcoming. It was well stocked with everything you could possibly need. We would definitely stay again."
Stacey W.
The price is £324
includes taxes & fees
9 Nov - 10 Nov
4. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!Downtown
10.0 out of 10, Exceptional, (23 reviews)
"This home was cozy and convenient. Communication was great; they are kind folks that enjoy what they do! We are grateful we could stay there!"
Krystine F.
The price is £273
includes taxes & fees
16 Nov - 17 Nov
5. Renovated 3BR near Lake Keowee & Clemson
Renovated 3BR near Lake Keowee & ClemsonSeneca
10.0 out of 10, Exceptional, (2 reviews)
"Fantastic location and really nicely done home. It was a perfect touch having a desk in one of the rooms to be able to get work done."
Brenda B.
The price is £261
includes taxes & fees
11 Nov - 12 Nov
6. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Lake Retreat- Mins to CU- Kayaks, Fire Pit, DockSeneca
8.4 out of 10, Very good, (8 reviews)
"Adorable and clean house! The yard is beautiful "
Diana H.
The price is £220
includes taxes & fees
8 Nov - 9 Nov
7. 8 Mi to Clemson: Peaceful Family Home w/ Yard
8 Mi to Clemson: Peaceful Family Home w/ YardSeneca
10.0 out of 10, Exceptional, (14 reviews)
"There for business. It’s a nice house in a good location and a great price"
James W.
8. Lakefront Retreat l Near Clemson, Hot Tub, Game Room, Kayaks, Private Dock
Lakefront Retreat l Near Clemson, Hot Tub, Game Room, Kayaks, Private DockSeneca
9.6 out of 10, Exceptional, (13 reviews)
"We had a great time at Seneca Lake House. We would definitely stay here again. "
Scott M.
The price is £610
includes taxes & fees
17 Nov - 18 Nov
9. The Big Golf House- 10 miles to Clemson
The Big Golf House- 10 miles to ClemsonSeneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
David E.
The price is £429
includes taxes & fees
11 Nov - 12 Nov
10. Waterfront 3br home on Lake Hartwell near Clemson
Waterfront 3br home on Lake Hartwell near ClemsonSeneca
9.8 out of 10, Exceptional, (19 reviews)
"We enjoyed our stay. Had everything we needed. "
Diane S.
The price is £368
includes taxes & fees
11 Nov - 12 Nov
11. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the StadiumSeneca
9.6 out of 10, Exceptional, (14 reviews)
"Everything was lovely."
Allison C.
The price is £486
includes taxes & fees
8 Nov - 9 Nov
12. Clemson Memorabilia House Frank Howard III’s Home
Clemson Memorabilia House Frank Howard III’s HomeClemson
8.6 out of 10, Excellent, (21 reviews)
"Great location!"
Libby S.
The price is £189
includes taxes & fees
9 Nov - 10 Nov
13. Modern and Spacious 2-floor Townhome Close to CU!
Modern and Spacious 2-floor Townhome Close to CU!Clemson
The price is £236
includes taxes & fees
7 Nov - 8 Nov
14. The Rustic Rectangle
The Rustic RectanglePendleton
10.0 out of 10, Exceptional, (13 reviews)
"Cozy, clean and quiet! Loved that we could have our dogs stay with us! "
Jennifer T.
The price is £167
includes taxes & fees
9 Nov - 10 Nov
15. Dream Weaver Cottage • Private Hot Tub • Fenced Yard • Pets Stay Free
Dream Weaver Cottage • Private Hot Tub • Fenced Yard • Pets Stay FreeWestminster
10.0 out of 10, Exceptional, (33 reviews)
"Loved this house for a quick get away. Everything you needed was there and more"
Anneli v.
The price is £235
includes taxes & fees
7 Dec - 8 Dec
17. Our Nest, a well loved quiet retreat in Foxwood Hills Resort near Lake Hartwell.
Our Nest, a well loved quiet retreat in Foxwood Hills Resort near Lake Hartwell.Westminster
9.8 out of 10, Exceptional, (10 reviews)
"Outstanding place and host. Will definitely stay here again. "
William H. J.
The price is £167
includes taxes & fees
1 Dec - 2 Dec
18. Lake Hartwell Covered Dock & Sunset Beach 3BD, 1BA
Lake Hartwell Covered Dock & Sunset Beach 3BD, 1BAFair Play
9.6 out of 10, Exceptional, (62 reviews)
"The cottage was very nice. Great view of the water. super easy walk to the water. Dock & kayaks were enjoyed. "
Steve A.
The price is £246
includes taxes & fees
7 Nov - 8 Nov
19. Clemson | Lakefront | HotTub | Sauna | Gym | SUPs
Clemson | Lakefront | HotTub | Sauna | Gym | SUPsTownville
The price is £489
includes taxes & fees
9 Nov - 10 Nov
20. Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski OptionWest Union
9.6 out of 10, Exceptional, (17 reviews)
"We had a great stay and all agreed it was an incredible week (ages 1-69.) The house was clean and well maintained, the amenities were terrific, very easy check in and check out, and we had great communication with the host. The lake view is beautiful and it is an easy walk down to the dock. One child said the place was better than Disney World."
Helen B.
The price is £878
includes taxes & fees
9 Nov - 10 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Seneca
Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.
Top reviews in Seneca
The Inn at Patrick Square
The Inn at Patrick SquareClemson
10/10 Excellent
Very nice hotel. Some small items were available for breakfast, unfortunately, the full service breakfast availability nearby was lacking. It did not open until 8 am (on a Friday).
Mark
