Photo by Cindy Keese

Search Holiday Homes in Seneca

    price find illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Next weekend
11 Jul - 13 Jul
In two weeks
18 Jul - 20 Jul
In one month
1 Aug - 3 Aug
In two months
29 Aug - 31 Aug

Browse Select Seneca Holiday Homes

4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
Property grounds

4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.

9.8 out of 10, Exceptional, (351)
"Everything I wrote in my previous reviews is still accurate."
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
Close to Lake Hartwell, Clemson, and Anderson
Smart TV

Close to Lake Hartwell, Clemson, and Anderson

10.0 out of 10, Exceptional, (51)
"Quick visit to the upstate from Charleston to visit our Clemson student. Love the location, very clean, updated and quiet. We hope to visit again soon. "
Close to Lake Hartwell, Clemson, and Anderson
Lake Jocassee ~ Easy Lake Access ~ Loved By Our Guests ~ Pet Friendly
Dining

Lake Jocassee ~ Easy Lake Access ~ Loved By Our Guests ~ Pet Friendly

9.8 out of 10, Exceptional, (86)
"This charming house was the perfect getaway for our trip! Plenty of room for our two trucks and trailers, clean and cozy with all the things we needed. Clear instructions for checking in and out. Minutes from the boat ramp at Devils Fork State Park!"
Lake Jocassee ~ Easy Lake Access ~ Loved By Our Guests ~ Pet Friendly
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water
Dining

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water

9.8 out of 10, Exceptional, (148)
"We had a great time at this house. Nice quite location, excellent dock in deep water for boating and fishing. Close to town but not a lot of traffic. "
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water
Lakehouse Retreat with dock, paddle boat, canoe & kayaks! Now have Gas Grill
Terrace/patio

Lakehouse Retreat with dock, paddle boat, canoe & kayaks! Now have Gas Grill

10.0 out of 10, Exceptional, (172)
"Had a great time on the dock each night "
Lakehouse Retreat with dock, paddle boat, canoe & kayaks! Now have Gas Grill
Gameday Getaway! - Less than 2 miles from Death Valley!
Terrace/patio

Gameday Getaway! - Less than 2 miles from Death Valley!

2.0 star property
10.0 out of 10, Exceptional, (5)
"Looking forward to potentially staying again; a great option for families. Well put together spaces and accommodations. Property manager was available and easy to communicate with when we did have some questions. Had we not needed to contact them, the information they sent us would have otherwise been more than sufficient.Thank you!"
Gameday Getaway! - Less than 2 miles from Death Valley!
Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.
Exterior

Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.

10.0 out of 10, Exceptional, (20)
"Overall fantastic experience! Great location and property manager was amazing with communication."
Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.
NEW!Lakefront retreat with huge dock, private cove. Perfect for Clemson Football
Outdoor dining

NEW!Lakefront retreat with huge dock, private cove. Perfect for Clemson Football

10.0 out of 10, Exceptional, (23)
"Such a great house, it has everything that you need, super clean and the Hosts are such an amazing people! We highly recommend this place!"
NEW!Lakefront retreat with huge dock, private cove. Perfect for Clemson Football
LAKEFRONT Retreat! <br>Escape To Lake Hartwell in this lakeside cottage!
Fridge, microwave, oven, stovetop

LAKEFRONT Retreat! <br>Escape To Lake Hartwell in this lakeside cottage!

10.0 out of 10, Exceptional, (44)
"Clean, comfy, quiet"
LAKEFRONT Retreat! <br>Escape To Lake Hartwell in this lakeside cottage!
Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson.
Outdoor pool, a heated pool

Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson.

9.4 out of 10, Exceptional, (66)
"Spacious Pool was great"
Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson.
Lakefront Westminster Retreat w/ Boat Dock!
Fridge, microwave, stovetop, dishwasher

Lakefront Westminster Retreat w/ Boat Dock!

9.0 out of 10, Wonderful, (8)
"Loved our weekend at the lake. The house was perfect, had everything we needed. LOVE the screened in back porch. The water was amazing. Would definitely stay here again!"
Lakefront Westminster Retreat w/ Boat Dock!
Tranquil Lakefront Setting near Clemson SC with Private, Covered Dock
Property grounds

Tranquil Lakefront Setting near Clemson SC with Private, Covered Dock

9.8 out of 10, Exceptional, (76)
"This trip marked our second stay at this property. We love its location and the tranquil setting on the lake. If you are looking for a modest home complete with all of the necessities to make for a relaxing weekend, this property is for you."
Tranquil Lakefront Setting near Clemson SC with Private, Covered Dock
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Property grounds

Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!

10.0 out of 10, Exceptional, (51)
"We had a small group for a relaxing weekend away for my nieces sweet 16. They really enjoyed the kayaks and wild life around the property. We all enjoyed the peaceful area and the ability to have safe family and friend time. I will definitely be back for another relaxing getaway. "
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Serene LAKEFRONT Retreat ON Lake Keowee near Clemson, SC
Fridge, microwave, oven, stovetop

Serene LAKEFRONT Retreat ON Lake Keowee near Clemson, SC

10.0 out of 10, Exceptional, (84)
"We stayed for our son’s Clemson graduation. Everything about our stay was excellent…It is a beautiful spot for a getaway! Our hosts' kindness and hospitality were wonderful! Thank you!"
Serene LAKEFRONT Retreat ON Lake Keowee near Clemson, SC
Perfect Summer get away! Charming 4 bedroom lake front home.
Exterior

Perfect Summer get away! Charming 4 bedroom lake front home.

10.0 out of 10, Exceptional, (23)
"Clean, stocked loved it will definitely stay again if we are in the area again!"
Perfect Summer get away! Charming 4 bedroom lake front home.
Lakefront Keowee Home w/ Dock, 14 Mi to Clemson
Interior

Lakefront Keowee Home w/ Dock, 14 Mi to Clemson

10.0 out of 10, Exceptional, (65)
"Good communication with host, easy checkout instructions, convenient area less 10 minutes from a lot of restaurants and Great Lake access. Great views of lake from all the porches. Just a really good experience ."
Lakefront Keowee Home w/ Dock, 14 Mi to Clemson
NEWLY RENOVATED DECK! Private lakefront home minutes from Clemson; private dock
Property grounds

NEWLY RENOVATED DECK! Private lakefront home minutes from Clemson; private dock

9.6 out of 10, Exceptional, (80)
"The property met all expectations. Loved the screened in porch."
NEWLY RENOVATED DECK! Private lakefront home minutes from Clemson; private dock
Incredible 10 BR home with pool
Property grounds

Incredible 10 BR home with pool

9.4 out of 10, Exceptional, (3)
"We used this location for a staff off site 2 day meeting. The rooms were fantastic, the outdoor space amazing and the little living spaces for smaller meetings worked well. I think we will definitely use this house again. The property management people were very responsive. Beautiful house!"
Incredible 10 BR home with pool
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Property grounds

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock

9.6 out of 10, Exceptional, (166)
"Beautiful spot at the end of a quiet road with water access. Cozy property that could accomodate a large family. Very comfortable and relaxing"
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Large home with Mountain Views & 20 min from town
Terrace/patio

Large home with Mountain Views & 20 min from town

9.8 out of 10, Exceptional, (41)
"We really enjoyed ourselves. Perfect setting for a large family to all get together with plenty of room. The amenities were more then adequate. We would love to stay there again!"
Large home with Mountain Views & 20 min from town
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free