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Our top choices for Seneca holiday rentals

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (69 reviews)
"Excellent stay."
United States
Beonca
The price is £113
includes taxes & fees
28 Apr - 29 Apr
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
The price is £164
includes taxes & fees
26 Apr - 27 Apr
Cozy Clemson TIny House Cabin

8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
3.0 star property
Seneca
10.0 out of 10, Exceptional, (1 review)
"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."
United States
Jason
8 Mi to Clemson: Peaceful Family Home w/ Yard

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (12 reviews)
"Very clean and comfortable - very close to Clemson and easy access. "
United States
Jim A.
The price is £150
includes taxes & fees
27 Apr - 28 Apr
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

bedroom available in my house in lovely Seneca. 5 miles from Clemson University

bedroom available in my house in lovely Seneca. 5 miles from Clemson University
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Rooms were clean and host was accommodating. Room to park my boat and was able to bring my dog!"
United States
Matthew A.
The price is £66
includes taxes & fees
30 Apr - 1 May
bedroom available in my house in lovely Seneca. 5 miles from Clemson University

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
Seneca
10.0 out of 10, Exceptional, (22 reviews)
"Very nice accommodations and great location for stay in Clemson. "
United States
Marisa G.
The price is £304
includes taxes & fees
4 May - 5 May
Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
10.0 out of 10, Exceptional, (9 reviews)
"We enjoyed our stay. Had everything we needed. "
United States
Diane S.
The price is £393
includes taxes & fees
24 Apr - 25 Apr
Waterfront 3br home on Lake Hartwell near Clemson

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (17 reviews)
"Great home base for a Clemson game. "
United States
Karen A.
The price is £230
includes taxes & fees
26 Apr - 27 Apr
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Seneca
The price is £232
includes taxes & fees
26 Apr - 27 Apr
Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Seneca
7.8 out of 10, Good, (6 reviews)
"Everything was in great condition! Items provided were good quality. You can tell a lot of time and thought has been put into this property. We would love to stay again. "
United States
Alisa W.
The price is £348
includes taxes & fees
23 May - 24 May
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Carolina Cottage Retreat-12 Minutes from Clemson University

Carolina Cottage Retreat-12 Minutes from Clemson University
Seneca
Carolina Cottage Retreat-12 Minutes from Clemson University

Close to Mountains, Clemson, Asheville, Marina & Best Lake in the Carolinas

Close to Mountains, Clemson, Asheville, Marina & Best Lake in the Carolinas
Seneca
9.0 out of 10, Wonderful, (62 reviews)
"Great location well stocked kitchen ,kayak paddle board pink pong fuse ball"
United States
Walter B.
The price is £547
includes taxes & fees
3 May - 4 May
Close to Mountains, Clemson, Asheville, Marina & Best Lake in the Carolinas

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
Serenity Bay
9.8 out of 10, Exceptional, (130 reviews)
"Beautiful home, well furnished, very clean, easy TV"
United States
Alan
The price is £551
includes taxes & fees
24 Apr - 25 Apr
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Absolutely! Perfect space for our needs, so for accommodating for our family & pet. "
United States
Gennifer Q.
The price is £391
includes taxes & fees
26 Apr - 27 Apr
The Big Golf House- 10 miles to Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.6 out of 10, Exceptional, (8 reviews)
"Great place with a lot close by"
United States
Aldor D.
The price is £283
includes taxes & fees
26 Apr - 27 Apr
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Seneca
9.4 out of 10, Exceptional, (9 reviews)
"Very accommodating host. Property is a great location and very clean. "
United States
Craig F.
The price is £512
includes taxes & fees
27 Apr - 28 Apr
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Johnsons Cove - Lakefront Retreat With EV Charger

Johnsons Cove - Lakefront Retreat With EV Charger
Seneca
10.0 out of 10, Exceptional, (1 review)
"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."
United States
Rebecca G.
Johnsons Cove - Lakefront Retreat With EV Charger

The Pendle-Tin

The Pendle-Tin
Pendleton
9.8 out of 10, Exceptional, (10 reviews)
"Property was cute, cozy and perfect for our short 2 night stay! Clean and distance to campus was great! "
United States
Cindy L.
The price is £157
includes taxes & fees
4 May - 5 May
The Pendle-Tin

Glamping with a partial lake view, 30 minutes to Clemson University

Glamping with a partial lake view, 30 minutes to Clemson University
Westminster
9.4 out of 10, Exceptional, (14 reviews)
"The camper was very clean and the set up was very nice. Didn’t have a view of the lake, but all in all had a very nice stay. "
United States
Scott S.
The price is £163
includes taxes & fees
27 Apr - 28 Apr
Glamping with a partial lake view, 30 minutes to Clemson University

Lake Hartwell Rental w/Dock

Lake Hartwell Rental w/Dock
Fair Play
10.0 out of 10, Exceptional, (56 reviews)
"Michelle and the crew were awesome. I’d recommend staying there to anyone!"
United States
Christopher L.
The price is £279
includes taxes & fees
26 Apr - 27 Apr
Lake Hartwell Rental w/Dock
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Find out more about Seneca

Everything you need to know about Seneca holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Seneca holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Seneca holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Seneca holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Seneca. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Seneca holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Seneca holiday rentals we have selected for you start as low as £66 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Seneca rentals

At Expedia, we put the best Seneca holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Seneca rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Seneca holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Seneca. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there holiday rentals in Seneca?

Yes, there are holiday rentals in Seneca close to Blue Ridge Arts Center, or you can select a more secluded option if you're looking for a relaxing stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffee shops.

What are some of the best holiday rentals that Seneca has to offer?

Charming and Entertaining Lake House Retreat for Large Groups!: This highly rated holiday home rental in Seneca offers 1 hot tub, a BBQ and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a stovetop and a microwave. Some other homes for rent in Seneca include Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock and 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!.

How many holiday rentals are there in Seneca?

Choose from 207 Expedia holiday rentals in Seneca for a memorable holiday.

What’s there to see and do in Seneca?

Cultural attractions include Oconee Community Theatre and The Gauntlet, whereas Lake Keowee and Lake Hartwell are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Oconee County Library Seneca Branch are other places worth a visit.

What’s a holiday rental in Seneca like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Seneca. Holiday rentals offer extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about a sanitised environment, a holiday rental can offer a sense of seclusion away from public hotel lifts and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is an attractive choice for family trips.