Title: Holiday Rentals Seneca from £95: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Hotels in Seneca](https://expedia.co.uk/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Flights to Seneca](https://expedia.co.uk/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Seneca Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Seneca.d6548.Car-Hire-Guide)[Seneca Holidays](https://expedia.co.uk/Seneca.d6548.Holidays-City-Breaks) ![An overlooking view in Seneca, South Carolina](https://images.trvl-media.com/place/6548/dae46ccf-db63-4268-bbdf-1e7406fb8f30.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6548/dae46ccf-db63-4268-bbdf-1e7406fb8f30.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6548&startDate=2026-01-30&endDate=2026-02-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6548&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6548&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [8 May - 10 May](https://www.expedia.co.uk/Hotel-Search?regionId=6548&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Seneca holiday rentals ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/c4a9a8fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/2da98b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/53271cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/ec2a8fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) 9.8/10 Exceptional (54 reviews) "Excellent stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beonca £95 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/40d3b059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/89ea8ad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/ec808a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/1da4db10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Home in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information) 10/10 Exceptional (12 reviews) "Adorable and clean home convenient to Clemson’s campus. We enjoyed our stay and Tyler was an exceptional host! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mandy H. £290 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information) ![Smart TV, video games, ping pong](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/eea5ec7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/5e61ee35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/5f42512b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/c53fb178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-Lakeside-Clemson-Condo-With-4KSurround-SoundXboxCoffee-BarPrivate-Bathrooms.h97053582.Hotel-Information) 10/10 Exceptional (21 reviews) "Very nice accommodations and great location for stay in Clemson. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marisa G. £253 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Seneca-Hotels-Lakeside-Clemson-Condo-With-4KSurround-SoundXboxCoffee-BarPrivate-Bathrooms.h97053582.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/w1536h2048x0y0-6998e207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/ad885ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/405dd7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/c9812bb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information) £166 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/124000000/123610000/123600800/123600709/d615cc6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/124000000/123610000/123600800/123600709/1bfa4ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123610000/123600800/123600709/35d2628f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![WiFi, bed sheets](https://images.trvl-media.com/lodging/124000000/123610000/123600800/123600709/82296468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camping in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-So-Mushroom-Silver-Streak-Travel-Trailer.h123600709.Hotel-Information) £122 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Seneca-Hotels-So-Mushroom-Silver-Streak-Travel-Trailer.h123600709.Hotel-Information) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/c027128d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/5ddade10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/84d2a4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/9e13146e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Home in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information) 10/10 Exceptional (2 reviews) "Absolutely! Perfect space for our needs, so for accommodating for our family & pet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gennifer Q. £399 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/fc891652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/d33a6537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/d37b415d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/98c8974f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Home in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information) 9.6/10 Exceptional (8 reviews) "Owner was on point with contact prior to arrival and during stay. Check in was super easy and property was clean and decorated nicely. Everything that we needed was already at the house. There is a marina close by with restaurant also." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin J. £506 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/0834ba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/ab96edf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/c941d493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/51bdec15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Home in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information) 8.0/10 Very good (3 reviews) "Everything was in great condition! Items provided were good quality. You can tell a lot of time and thought has been put into this property. We would love to stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alisa W. £221 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/67979a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/c5a2afe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/4513793e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/424e1883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camping in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information) 10/10 Exceptional (12 reviews) "Very clean and comfortable - very close to Clemson and easy access. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jim A. £152 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/7bfcd263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/fa054611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/bf812e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/8d32bcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Home in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information) 10/10 Exceptional (5 reviews) "Great place with a lot close by" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aldor D. £234 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information) ![4 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/41018e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/3ef9dbf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/aad65738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, printers](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/d0ce4a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Home in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger-Family-And-Pet-Friendly.h114843702.Hotel-Information) 10/10 Exceptional (1 review) "We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca G. £591 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger-Family-And-Pet-Friendly.h114843702.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/825f9309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, stereo](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/735219a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/91ac5b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/ce0e5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Home in Serenity Bay [](https://www.expedia.co.uk/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information) 9.8/10 Exceptional (130 reviews) "A wonderful stay! The house offered many different spaces and the lake access/dock was perfect!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) stacy s. £461 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/107000000/106120000/106116600/106116530/8cc7e5ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106120000/106116600/106116530/dbdc80ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, stereo](https://images.trvl-media.com/lodging/107000000/106120000/106116600/106116530/061a9e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, Internet, bed sheets](https://images.trvl-media.com/lodging/107000000/106120000/106116600/106116530/9b67ec16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Home in Seneca [](https://www.expedia.co.uk/Seneca-Hotels-Lake-Keowee-Retreat-4BR-With-Hot-Tub-Dock.h106116530.Hotel-Information) 6.4/10 (5 reviews) "Main floor was clean but basement and loft, cleaners missed a lot. It was very dusty with lots of cobwebs. Cleaners have missed a lot of places over and over again. The downstairs deck was full of pollen and so dirty we couldn’t sit out there. Wish there was an umbrella on top deck- no shade or cover when rains. Wish there was somewhere to put suitcases but w no closet space and no dresser tops, suitcases were all over floors. Was just hoping for a cleaner space for what we paid. Overall it was... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristen F. £416 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Seneca-Hotels-Lake-Keowee-Retreat-4BR-With-Hot-Tub-Dock.h106116530.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/106000000/105490000/105489100/105489096/8bba3903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105490000/105489100/105489096/bd6f0d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105490000/105489100/105489096/d70b5cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, travel cot, free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105489100/105489096/5c7a4b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mobile Home in Westminster [](https://www.expedia.co.uk/Westminster-Hotels-Glamping-With-A-Partial-Lake-View.h105489096.Hotel-Information) 9.4/10 Exceptional (14 reviews) "The camper was very clean and the set up was very nice. Didn’t have a view of the lake, but all in all had a very nice stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott S. £164 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Westminster-Hotels-Glamping-With-A-Partial-Lake-View.h105489096.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/88000000/87140000/87136100/87136049/9e5b3cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87140000/87136100/87136049/28889e9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/88000000/87140000/87136100/87136049/24954e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/88000000/87140000/87136100/87136049/31949138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mobile Home in Pendleton [](https://www.expedia.co.uk/Pendleton-Hotels-The-Pendle-Tin.h87136049.Hotel-Information) 9.8/10 Exceptional (9 reviews) "Perfect for weekend getaway!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregg H. £142 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Pendleton-Hotels-The-Pendle-Tin.h87136049.Hotel-Information) ![Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/a4df93b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/b86441f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | 2 bedrooms, individually decorated, individually furnished](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/9cd5859a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 2 Bedrooms | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/0d77f138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Clemson [](https://www.expedia.co.uk/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information) 9.8/10 Exceptional (9 reviews) "We enjoyed our stay, it was the perfect size for our family of four. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley £178 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/0fa322d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, travel cot, WiFi](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/6ea9c430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/fcc5512f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99950000/99942200/99942155/43fd0878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Clemson [](https://www.expedia.co.uk/Clemson-Hotels-Ballgame-Bungalow.h99942155.Hotel-Information) 9.2/10 Wonderful (9 reviews) "We had a great stay in this clean and centrally located two bedroom place - including quick communication with the property managers when we had some problems with the WiFi! Loved the location, will absolutely visit again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Agatha L. £270 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Clemson-Hotels-Ballgame-Bungalow.h99942155.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/81000000/80020000/80018300/80018274/66bedfb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/81000000/80020000/80018300/80018274/6a9a51e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/81000000/80020000/80018300/80018274/b0a5a6fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/81000000/80020000/80018300/80018274/02c108b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Anderson [](https://www.expedia.co.uk/Anderson-Hotels-A-Frame-Cottage-W-Hot-Tub-On-Lake-Hartwell.h80018274.Hotel-Information) 9.8/10 Exceptional (82 reviews) "This house was perfect for our family for the weekend, very comfortable and peaceful. The house had everything we needed and more, and hot was very thoughtful and communicative. We enjoyed kayaking on the lake and hiking in the area, would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corrie H. £199 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Anderson-Hotels-A-Frame-Cottage-W-Hot-Tub-On-Lake-Hartwell.h80018274.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110820000/110812100/110812036/f95c7c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/111000000/110820000/110812100/110812036/3a781422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/111000000/110820000/110812100/110812036/5ca265fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110820000/110812100/110812036/2eb8978f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Townville [](https://www.expedia.co.uk/Townville-Hotels-Broyles-Landing-Cottage-At-Lake-Hartwell-SC.h110812036.Hotel-Information) 10/10 Exceptional (17 reviews) "Easy check in, the place was stocked with awesome snacks we werent expecting. The cots were very comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Damian D. £151 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Townville-Hotels-Broyles-Landing-Cottage-At-Lake-Hartwell-SC.h110812036.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-31&endDate=2026-02-01®ionId=6548&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-20&d2=2026-04-20&lodging=CABIN) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-20&d2=2026-04-20&lodging=APARTMENT) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-20&d2=2026-04-20&lodging=VACATION_HOME) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-20&d2=2026-04-20&lodging=COTTAGE) Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-20&d2=2026-04-20&lodging=APART_HOTEL) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-20&d2=2026-04-20&lodging=CONDO) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-20&d2=2026-04-20&lodging=VILLA) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-20&d2=2026-04-20&lodging=HOUSE_BOAT) Chalets [](https://www.expedia.co.uk/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-20&d2=2026-04-20&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Holiday-Rentals.d6548.Travel-Guide-HolidayRentals)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Holiday-Rentals.d6548.Travel-Guide-HolidayRentals) ## Top Seneca Hotel Reviews ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "We stayed at this hotel over the weekend to celebrate our anniversary, and it turned into one of the best hotel experiences we’ve ever had. My fiancée and I were looking for something special, and Jennifer suggested their decorated room for occasions like this. I trusted her recommendation, and I’m so glad I did. The moment we walked into the room, we were honestly amazed. It was beautifully decorated from top to bottom. The bed setup was perfect, the details were thoughtful, and the atmosphere felt romantic and relaxing. The jacuzzi tub inside the bedroom was the highlight. It made the whole experience feel extra special. We truly enjoyed every moment of our stay and created memories we’ll always remember. I would highly recommend this hotel to anyone celebrating a special occasion." [](https://expedia.co.uk/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Tru by Hilton Seneca Clemson](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8_y.jpg) ### Tru by Hilton Seneca Clemson 10/10 Excellent "The staff here are top tier! We had to be at a meet at the university by 6am and they made breakfast early so our kids could eat before the meet! Genuine care for their guest! Love it here! " [](https://expedia.co.uk/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "The staff especially stood out. The online check in and the front desk was an absolute breeze! I am pleased as all heck. The room was clean and is well laid out for me to work. I greatly appreciate it." [](https://expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.](https://images.trvl-media.com/lodging/58000000/57860000/57854500/57854431/90607bc4_y.jpg) ### 6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water. 10/10 Excellent "We had an amazing weekend! The house was comfortable and relaxing. The check-in and check-out process were very easy. " [](https://expedia.co.uk/Anderson-Hotels-Newly-Furnished-And-Renovated-Lake-House-Directly-On-Hartwell.h57854431.Hotel-Information) ![Quality Inn Seneca Clemson Area US-123](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg) ### Quality Inn Seneca Clemson Area US-123 10/10 Excellent "Hotel was clean, inside and out. Front desk staff was very kind and helpful. " [](https://expedia.co.uk/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub](https://images.trvl-media.com/lodging/62000000/61650000/61640700/61640625/6343a107_y.jpg) ### Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub 10/10 Excellent "Great well stocked house, comfortable beds, had everything we needed and more." [](https://expedia.co.uk/Seneca-Hotels-Beautiful-Waterfront-Home-On-A-Private-Cove-In-Lake-Keowee-W-Hot-Tub.h61640625.Hotel-Information) ![Hampton Inn & Suites Seneca-Clemson Area](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg) ### Hampton Inn & Suites Seneca-Clemson Area 10/10 Excellent "Check-in was fast and efficient. Our room was clean and spacious. Temperature control was great. Beds were comfy. The breakfast each morning was great, providing sources of protein and fruits as well as the typical continental selections, but they actually had a vat of grits that were just about the right thickness and consistency - just what a Southern boy needs!" [](https://expedia.co.uk/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789_y.jpg) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy 10/10 Excellent "Excellent stay." [](https://expedia.co.uk/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![ Enjoy one of our RV units son less of a headache for you this vacation!](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c0b82041_y.jpg) ### Enjoy one of our RV units son less of a headache for you this vacation! 10/10 Excellent "My partner and I stayed 5 nights and we enjoyed it so much. It's such a convenient place to reside for a get away. If you're looking for that "outback" feeling but want to be cozy; look no further. Communication was always qick with responses and was more than willing to help with anything we needed! We would definitely stay again." [](https://expedia.co.uk/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information) ## Find out more about Seneca **Everything you need to know about** **Seneca** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Seneca holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Seneca holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Seneca holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Seneca. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Seneca holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Seneca holiday rentals we have selected for you start as low as £95 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Seneca rentals** At Expedia, we put the best Seneca holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Seneca rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Seneca holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Seneca. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk - All accommodation types in Seneca ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold ](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District ](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals ](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - [Herefordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Herefordshire.d6046203.Holiday-Rental-Destinations) - [Essex Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Essex.d6046201.Holiday-Rental-Destinations) - [Cumbria Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cumbria.d6046194.Holiday-Rental-Destinations) - [Yorkshire Holiday Rentals ](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals) - [South Wales Holiday Rentals ](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals) - [North Wales Holiday Rentals ](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals) - [London Holiday Rentals ](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals) - [York Holiday Rentals ](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals) - [Blackpool Holiday Rentals ](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals) - [Isle of Wight Holiday Rentals ](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations) - [Scarborough Holiday Rentals ](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals) - [Edinburgh Holiday Rentals ](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals) - [Bath Holiday Rentals ](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals) - [Bournemouth Holiday Rentals ](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals) - [England Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations) - [Scotland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations) - [Cornwall Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations) - [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations) - [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations) - [Holiday Homes in Seneca ](https://expedia.co.uk/Seneca-Private-Holiday-Homes.d6548-aaPrivateHolidayHomes.Travel-Guide-Accommodation) ## Frequently asked questions ### Are there holiday rentals in Seneca? ### What are some of the best holiday rentals that Seneca has to offer? ### How many holiday rentals are there in Seneca? ### What’s there to see and do in Seneca? ### What’s a holiday rental in Seneca like? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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