A calm lake with mountains in the background.

Search Holiday Rentals in Seneca

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Seneca holiday rentals

1. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (103 reviews)
"Me and my family had a great time"
United States
Nirumol
The price is £108
includes taxes & fees
20 Sept - 21 Sept
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2. Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
10.0 out of 10, Exceptional, (3 reviews)
"The property was very clean and well maintained. The living space is large and the bathroom quite large as well. It was perfect for our needs. It is close to everything in the area. Jim was extremely helpful and super quick with his responses to our questions."
United States
Peter M.
The price is £166
includes taxes & fees
15 Sept - 16 Sept
Cozy Clemson TIny House Cabin

3. The Nest Above - Sparrow Suite

The Nest Above - Sparrow Suite
Downtown
10.0 out of 10, Exceptional, (1 review)
"Charming stay in the downtown area. Walking distance to restaurants and events on Ramcat Alley. We enjoyed our stay and wipp stay again on our next trip to the upstate."
United States
Deborah R.
The Nest Above - Sparrow Suite

4. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.8 out of 10, Exceptional, (12 reviews)
"Easy check in, pet-friendly, great location!!"
United States
Jason M.
The price is £287
includes taxes & fees
17 Sept - 18 Sept
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

5. Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Seneca
10.0 out of 10, Exceptional, (1 review)
"Beautiful home, no complaints."
United States
Brenda
The price is £242
includes taxes & fees
13 Sept - 14 Sept
Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

6. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (22 reviews)
"Great host! We had a great experience during our stay. "
United States
David E.
The price is £286
includes taxes & fees
14 Sept - 15 Sept
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

7. Carolina Cottage Retreat-12 Minutes from Clemson University

Carolina Cottage Retreat-12 Minutes from Clemson University
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"We were very pleased with our stay. Four bedrooms was perfect for us. The little coffee bar was an enjoyable perk!"
United States
Karen S.
The price is £241
includes taxes & fees
22 Sept - 23 Sept
Carolina Cottage Retreat-12 Minutes from Clemson University

8. Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
9.8 out of 10, Exceptional, (15 reviews)
"We enjoyed our stay. Had everything we needed. "
United States
Diane S.
The price is £390
includes taxes & fees
13 Sept - 14 Sept
Waterfront 3br home on Lake Hartwell near Clemson

9. Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (15 reviews)
"Perfect pet friendly spot to enjoy a weekend getaway! Quiet campground, homey vibe, and awesome location!"
United States
Josie G.
The price is £151
includes taxes & fees
14 Sept - 15 Sept
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

10. Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Fantastic location and really nicely done home. It was a perfect touch having a desk in one of the rooms to be able to get work done."
United States
Brenda B.
The price is £284
includes taxes & fees
23 Sept - 24 Sept
Renovated 3BR near Lake Keowee & Clemson

11. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Seneca
9.6 out of 10, Exceptional, (11 reviews)
"Everything was lovely."
United States
Allison C.
The price is £518
includes taxes & fees
14 Sept - 15 Sept
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

12. Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit

Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit
3.0 star property
Seneca
The price is £580
includes taxes & fees
27 Sept - 28 Sept
Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit

13. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Seneca
The price is £322
includes taxes & fees
22 Sept - 23 Sept
Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

14. The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
United States
David E.
The price is £459
includes taxes & fees
23 Sept - 24 Sept
The Big Golf House- 10 miles to Clemson

15. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Seneca
8.0 out of 10, Very good, (7 reviews)
"Adorable and clean house! The yard is beautiful "
United States
Diana H.
The price is £215
includes taxes & fees
27 Sept - 28 Sept
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

16. Johnsons Cove - Lakefront Retreat With EV Charger

Johnsons Cove - Lakefront Retreat With EV Charger
Seneca
10.0 out of 10, Exceptional, (1 review)
"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."
United States
Rebecca G.
The price is £559
includes taxes & fees
14 Sept - 15 Sept
Johnsons Cove - Lakefront Retreat With EV Charger

17. Iroquois Crossroads - 10 min from Clemson & lakes

Iroquois Crossroads - 10 min from Clemson & lakes
Seneca
The price is £264
includes taxes & fees
23 Sept - 24 Sept
Iroquois Crossroads - 10 min from Clemson & lakes

18. Peaceful 3-bedroom home 4 miles from Clemson.

Peaceful 3-bedroom home 4 miles from Clemson.
Seneca
The price is £220
includes taxes & fees
15 Sept - 16 Sept
Peaceful 3-bedroom home 4 miles from Clemson.

19. Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson

Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson
Seneca
10.0 out of 10, Exceptional, (24 reviews)
"Great home and host"
United States
Anonymous traveller
The price is £1,063
includes taxes & fees
13 Sept - 14 Sept
Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Seneca Hotel Reviews

Find out more about Seneca

Everything you need to know about Seneca holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Seneca holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Seneca holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Seneca holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Seneca. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Seneca holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Seneca holiday rentals we have selected for you start as low as £108 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Seneca rentals

At Expedia, we put the best Seneca holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Seneca rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Seneca holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Seneca. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there holiday rentals in Seneca?

Yes, there are holiday rentals in Seneca close to Blue Ridge Arts Center, or you can select a more secluded option if you're looking for a relaxing stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffee shops.

What are some of the best holiday rentals that Seneca has to offer?

4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!: This highly rated holiday home rental in Seneca is located on a lake, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade/games room. Some other homes for rent in Seneca include Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock and New to VRBO! Big water views, private dock, pool table, 15 min Clemson!.

How many holiday rentals are there in Seneca?

Choose from 218 Expedia holiday rentals in Seneca for a memorable holiday.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Keowee Reservoir and Lake Keowee are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Lake Hartwell are other places worth a visit.

What’s a holiday rental in Seneca like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Seneca. Holiday rentals offer extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about a sanitised environment, a holiday rental can offer a sense of seclusion away from public hotel lifts and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is an attractive choice for family trips.