Seneca Holidays from £755

Book a Hotel + Flight or Car together to unlock savings

Photo by Deidree DeHart

  • Plan, book, travel with confidence

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    Better together

    Save up to £335 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Packages with flights are ATOL protected

Top Seneca Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Midtown Suites-Greenville

Midtown Suites-Greenville

2.5 out of 5
per person
5 Oct - 9 Oct
found 14 hours ago
Return direct flight included
London (LON) to Greenville (GSP)
8/10 Very Good! (1,006 reviews)
This place was in the middle of renovation. But the people were very nice and the room was clean. Stayed for 4 nights would stay again.

Reviewed on 13 Jul 2025

The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
per person
5 Oct - 9 Oct
found 14 hours ago
Return direct flight included
London (LON) to Greenville (GSP)
9.8/10 Exceptional! (723 reviews)
Love this place! Second time staying here and would definitely come back again.

Reviewed on 11 Jul 2025

Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca
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Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and Keowee Key Golf Course.

Find hotels in Pine Ridge Point

Seneca Essential Information

Language
English
Currency
U.S dollars
Population
8,300
Max Temp Winter
10ºC
Max Temp Summer
32ºC

Top hotels in Seneca

Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is £91 per night from 15 Jul to 16 Jul
£91
15 Jul - 16 Jul
includes taxes & fees
9/10 Wonderful! (938 reviews)
"Very spacious. Great location. Walk to shopping and dining."

Reviewed on 10 Jul 2025

Lakeside Lodge Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 out of 5
800 BYPASS 123, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is £105 per night from 15 Jul to 16 Jul
£105
15 Jul - 16 Jul
includes taxes & fees
9.4/10 Exceptional! (172 reviews)
"Liked the view of the lake and the large breakfast area. Breakfast was excellent."

Reviewed on 11 Jul 2025

Fairfield Inn & Suites Seneca Clemson Univ Area
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is £99 per night from 20 Jul to 21 Jul
£99
20 Jul - 21 Jul
includes taxes & fees
9.2/10 Wonderful! (608 reviews)
"convenient to our needs"

Reviewed on 30 Jun 2025

Hampton Inn & Suites Seneca-Clemson Area
See all 1,588 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Holidays

All Inclusive Holidays

Beach Holidays

Beach Holidays

Family Friendly Holidays

Family Friendly Holidays

Frequently asked questions

Why should I book my Seneca holiday with Expedia?
Choose Expedia to plan your next adventure simply and all in one convenient place. Our insider tip for scoring an unbeatable deal on a Seneca retreat? Bundle your accommodation, flights and/or car hire into a package holiday. Then add some fun tours and activities. Many bookings also come with flexible cancellation policies, so there's no need to stress if you have to switch up your travel plans. Round-the-clock help with changing and cancelling your trip is available via our Customer Service Portal link.
When is the best time of year to holiday in Seneca?
Love sightseeing but don't like big crowds? Plan your Seneca escape for September, October and December. Typically, it's a lot quieter than it is in February, June and July. Plan your getaway to Seneca according to what type of holiday you're looking for. January is the coolest month, when daytime temperatures average 5ºC. In July, the warmest month, you can expect averages of 26ºC during the day.
What is the top hotel for my holiday in Seneca?
Best Western Seneca-Clemson sets the scene for an unforgettable getaway in Seneca, offering all the amenities you'll need and more.
How do I get a cheap holiday to Seneca?
Creating your own Seneca holiday with Expedia is a smart way to save. We offer more than 400 air carriers and 321,000 hotels around the globe. With such a fantastic range to choose from, you'll have no hassles creating your dream escape. Learn more about how you can save money on your holiday when you combine your hotel and flight bookings with Expedia.
Do I need a visa for my Seneca holiday?
Visa requirements for Seneca vary based on your nationality and purpose of your visit. Be sure to check official government websites to determine if you need a visa for your trip. They'll also give you the most up-to-date information, including details about application procedures or any supporting documentation that might be necessary. Enquire about your visa requirements well ahead of time to ensure a hassle-free travel experience. Also check to see that your passport has at least six months validity from your return date.
What should I wear on my Seneca holiday?
First, think about the types of activities you'll be doing during your Seneca trip and travel with pieces that you can mix and match. For fashion inspiration or even information on dress codes, look up a few style blogs or relevant social media accounts. Daytime temperatures during January, Seneca's coolest month, are around 5ºC. July marks this destination's warmest month when the average daily temperature reaches 26ºC. Our top tip? Take the guesswork out of what to pack and check the weather forecast.
What does an Expedia Seneca holiday include?
Expedia has all you need to plan your Seneca trip, but how your package is structured is entirely up to you. Pick from any combination of flights, hotels and hire cars. Looking for some tours or experiences to keep you on the move? Once you've made your booking, you can add them on too. No matter your style or budget, there's a package to suit your needs. Private holiday homes and apartments are a couple of popular property types in Seneca. No matter your holiday style or group size, you can rely on Expedia for the flexibility and freedom to customise your next big adventure.
Does Expedia offer Book Now, Pay Later Seneca holidays?
Your bank balance shouldn't stop you from escaping on holiday, so Expedia has devised a solution to help. Now that we've formed a partnership with online lender Klarna, it's easier than ever to book a fabulous getaway without exhausting your savings. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your escape. Check out these flexible payment options:

  • Pay monthly holidays: Klarna offers convenient monthly payment plans that work for all budgets, so you can have that well-deserved holiday now.
  • No-deposit holidays: Clicking on the "book now" button is easier with this plan. With no upfront fee for your holiday, you can Book Now, Pay Later and start packing your bags.

Can I choose my airline with a Seneca Expedia holiday?
Expedia offers access to more than 400 partner airlines worldwide, so you sure can! Simply pick the carrier you want and create the perfect Seneca escape.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.