While San Polo offers a unique Venetian experience, Cannaregio and Castello are two neighbourhoods that share some similar characteristics.
Cannaregio, located to the north of San Polo, is one of Venice's largest and most residential districts. It's known for its authentic Venetian feel, with a mix of quiet canals, local shops, and a good selection of traditional restaurants. The northern part of Cannaregio, particularly around the Fondamenta della Misericordia and Rio della Sensa, has a pleasant atmosphere with many cicchetti bars.
This area is particularly good for travellers who appreciate a more local experience, away from the busiest tourist crowds, yet still want good access to the rest of Venice. It's well-connected by Vaporetto lines, and the Santa Lucia train station is also located here, making arrivals and departures convenient.
Castello, to the east of San Polo, is another extensive and diverse district. While it includes the bustling area around St. Mark's Square, its eastern parts offer a much calmer, more residential environment. Here you'll find charming squares like Campo San Giovanni e Paolo and the expansive gardens of the Giardini della Biennale, providing ample green space – a rarity in Venice.
Castello is a good choice for those seeking a tranquil base with plenty of space to wander, while still being within walking distance of major attractions.