Title: The Best Hotels in Murex Lakes, Sanibel - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in Sanibel](https://expedia.co.uk/Sanibel-Holiday-Rentals.d9791.Travel-Guide-HolidayRentals)[Flights to Sanibel](https://expedia.co.uk/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.co.uk/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Murex Lakes Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Murex-Lakes.d553248635976468770.Car-Hire-Guide)[Murex Lakes Holidays](https://expedia.co.uk/Murex-Lakes.d553248635976468770.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Murex Lakes, Sanibel - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976468770&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976468770&startDate=2025-12-20&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976468770&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976468770&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Murex Lakes hotels ![3 restaurants, breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/9bc89705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/bbf3ce91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite with Two Doubles, Beachfront, Balcony | Individually decorated, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/2e8856cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio with Two Doubles, Beachfront, Balcony | Individually decorated, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/3202bde7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort [](https://www.expedia.co.uk/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) 9.3 mi from Murex Lakes 9.0/10 Wonderful (1016) "Clean rooms, friendly staff, so much to do there and nearby " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa R £134 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/3bf7e12d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, stovetop](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/01114515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/35ad9ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Suite Two Queen Beds | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/74c618a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Fort Myers - Cape Coral [](https://www.expedia.co.uk/Fort-Myers-Hotels-Woodspring-Suites-Fort-Myers-Cape-Coral.h103186827.Hotel-Information) 18.1 mi from Murex Lakes 7.2/10 Good (146) "For the price, the sheets were clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dairon £62 includes taxes & fees 20 Dec - 21 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Woodspring-Suites-Fort-Myers-Cape-Coral.h103186827.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/2c59b397.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/8bc2b39a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/3dc7bcd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Kayaking](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/94b7632c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Boutique Resort - Fort Myers Beach [](https://www.expedia.co.uk/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) 9.7 mi from Murex Lakes 8.8/10 Excellent (1001) "Great Place to Stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JUDY £95 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/a69cd385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/798de6a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/bd66e5bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/9ecc1017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG [](https://www.expedia.co.uk/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) 10.9 mi from Murex Lakes 9.4/10 Exceptional (1001) "Great rooms, good staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dedan £95 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/ece913ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/432e75cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/ef17c48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/e00a9bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Fort Myers Sanibel [](https://www.expedia.co.uk/Fort-Myers-Hotels-Residence-Inn-By-Marriott-Fort-Myers-Sanibel.h2625745.Hotel-Information) 8.8 mi from Murex Lakes 8.6/10 Excellent (1000) "The property was clean and the breakfast was excellent the staff was friendly and convenient to Sanibel Island" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) robert £86 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Residence-Inn-By-Marriott-Fort-Myers-Sanibel.h2625745.Hotel-Information) ![On the beach, sun-loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/f97bdde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Balcony (Gulf View) | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/f85ea0c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/aa9b23b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Island Beach Resort [](https://www.expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) Mid Island, 3.3 mi from Murex Lakes 9.2/10 Wonderful (1471) "Great place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £211 includes taxes & fees 20 Dec - 21 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/81b75b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/4e67b64f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/1a5de0b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/51a7dbde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral [](https://www.expedia.co.uk/Fort-Myers-Hotels-Fairfield-Inn-Suites-By-Marriott-Ft-MyersCape-Coral.h129295.Hotel-Information) 16 mi from Murex Lakes 8.6/10 Excellent (784) "Clean room and very nice staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £72 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Fairfield-Inn-Suites-By-Marriott-Ft-MyersCape-Coral.h129295.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/8dde6ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/dbfba1a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast (USD 15.95 per person)](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/fc5edcf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7 AM to 10 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/aaa8a4ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Ft Myers [](https://www.expedia.co.uk/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) 15.9 mi from Murex Lakes 8.8/10 Excellent (1009) "Great amenities, pool and spa, clean room, beautiful lobby and good on site restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aleksandar £88 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) ![Deluxe King Studio Waterfront | Water view](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/3722fead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe King Studio Waterfront | Premium bedding, pillow-top beds, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/cf6a8265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/057db752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/27000000/26920000/26914900/26914841/9079647e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Boutique Resort - Bonita Springs [](https://www.expedia.co.uk/Naples-Hotels-Latitude-26-Waterfront-Boutique-Resort.h26914841.Hotel-Information) 18.1 mi from Murex Lakes 8.8/10 Excellent (703) "Super location charming place, a total hidden gem!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jay [](https://www.expedia.co.uk/Naples-Hotels-Latitude-26-Waterfront-Boutique-Resort.h26914841.Hotel-Information) ![1 King Bed Suite w/ Efficiency Non Smoking | Premium bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/8f464d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed Suite w/ Efficiency Non Smoking | Premium bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/a487c18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/2c8820e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/5a136bee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Fort Myers Cape Coral [](https://www.expedia.co.uk/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers.h24286.Hotel-Information) 17.8 mi from Murex Lakes 7.6/10 Good (199) "Microwave made an explosion when tried to use it. The rest amazing" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alain £67 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers.h24286.Hotel-Information) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/d9487eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 2 Double Beds | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/7b4338be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 1 Queen Bed, Canal View | Living area | 50-inch TV with cable channels](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/4926d47c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served, al fresco dining ](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/68929405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lighthouse Resort Inn & Suites [](https://www.expedia.co.uk/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) 9.1 mi from Murex Lakes 8.6/10 Excellent (1569) "Great resort fun bar beautiful pool walkable area variety of restaurants and clean beach" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika £123 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Suite, 2 Bedrooms, Marina View | Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/39448802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Turkish bath/hammam, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/75a0f7eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/5f3015ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/8d0c7323.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Cape Coral Resort At Marina Village [](https://www.expedia.co.uk/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) 9.8 mi from Murex Lakes 9.0/10 Wonderful (1000) "Excellent stay over Thanksgiving holiday!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole £150 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![Outdoor pool, pool cabanas (surcharge), pool loungers](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/09777b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bars/lounges, beach bar](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/2c146761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun deck](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/46216370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/6aafbca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Beach Resort Fort Myers [](https://www.expedia.co.uk/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) 9.1 mi from Murex Lakes 9.0/10 Wonderful (1711) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra Sue £175 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/faba246e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/79444c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/cda8d432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1640000/1632700/1632691/1d6edbc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dolphin Key Resort [](https://www.expedia.co.uk/Fort-Myers-Hotels-Dolphin-Key-Resort.h1632691.Hotel-Information) 13.1 mi from Murex Lakes 8.8/10 Excellent (1208) "Nice room, helpful staff, nice heated pool, bar/restaurant on site has good prices and live entertainment most nights. Overall, a fun place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacob £83 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Dolphin-Key-Resort.h1632691.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/33000000/32030000/32023200/32023111/77436b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/33000000/32030000/32023200/32023111/6da633dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dock](https://images.trvl-media.com/lodging/33000000/32030000/32023200/32023111/8e8f56b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dolphin Tiny Home | Individually decorated, individually furnished, soundproofing, free WiFi](https://images.trvl-media.com/lodging/33000000/32030000/32023200/32023111/ae280548.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Matlacha Tiny Village [](https://www.expedia.co.uk/Fort-Myers-Hotels-Matlacha-Tiny-Village.h32023111.Hotel-Information) 13.6 mi from Murex Lakes 8.8/10 Excellent (268) "Very nice place with all necesary accommodations for a Pleasant stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) isabel £153 includes taxes & fees 20 Dec - 21 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Matlacha-Tiny-Village.h32023111.Hotel-Information) ![Classic Studio (Alligator) | Living area](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/7a5f7b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Studio (Butterfly) | Living area](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/9324697f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio (Parrot) | Living area](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/0d877650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Studio (Alligator) | Free WiFi](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/d5cdd3c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TriLuxe Inn & Studios [](https://www.expedia.co.uk/Fort-Myers-Hotels-TriLuxe-Inn-Studios.h112934495.Hotel-Information) 10.8 mi from Murex Lakes 8.2/10 Very good (17) "Everything was great, will definitely be coming back" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ruben £74 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-TriLuxe-Inn-Studios.h112934495.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/6f7b31fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/a68b2adb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/4358355b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12400/12375/d5eaf81c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Fort Myers at Bell Tower Shops [](https://www.expedia.co.uk/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) 16.5 mi from Murex Lakes 8.8/10 Excellent (1000) "Very nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley £106 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/Fort-Myers-Hotels-Doubletree-By-Hilton-Fort-Myers-At-Bell-Tower-Shops.h12375.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/7dc3b2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/a5e914cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/89400c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/1ba88bdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Ft. Myers [](https://www.expedia.co.uk/Fort-Myers-Hotels-Americas-Best-Value-Inn-Ft-Myers.h16889.Hotel-Information) 17.1 mi from Murex Lakes 7.6/10 Good (1122) "Loved it. The staff was great rooms were clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Austin £57 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Americas-Best-Value-Inn-Ft-Myers.h16889.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/6b04a862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/4f598667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/dd5699df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/8f32b7a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway [](https://www.expedia.co.uk/Fort-Myers-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Ft-Myers-Sanibel-Gateway.h11134.Hotel-Information) 9.1 mi from Murex Lakes 8.0/10 Very good (1002) "Nice staff, clean and convenient. Will stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Josephine £91 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Ft-Myers-Sanibel-Gateway.h11134.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/4900/4809/5633e2c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo | 1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/4900/4809/71f6e520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/1000000/10000/4900/4809/a04fe75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo | Living area | Flat-screen TV, DVD player, pay films](https://images.trvl-media.com/lodging/1000000/10000/4900/4809/d8cab195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pointe Estero Beach Resort [](https://www.expedia.co.uk/Fort-Myers-Hotels-Pointe-Estero-Beach-Resort.h4809.Hotel-Information) 12.2 mi from Murex Lakes 9.2/10 Wonderful (1002) "Could not beat the ocean view!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) BETH £383 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/Fort-Myers-Hotels-Pointe-Estero-Beach-Resort.h4809.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03®ionId=553248635976468770&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Murex Lakes Find the best Murex Lakes areas for the activities you enjoy most. - West End - Mid Island - East End - Beachview Country Club Estates - Sanctuary ![Fort Myers featuring a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31797-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography ![Fort Myers which includes signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31796-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography ![Fort Myers which includes island views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31793-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Dave Meardon Photography ![Fort Myers which includes a pebble beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31789-Sanibel-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Dave Meardon Photography ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/427000/427051-Sanibel-Captiva-Island.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Sanibel Captiva Chamber of Commerce/Dave Meardon Photography [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=977664051587067904) ![West End map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:egs%60DlmrtNyjAco%40Xei%40tyAkvB_%40evB%7EfCyvG%7ExAqa%40jfC%7BAyAzo%40mFpn%40o%7D%40ncDg_%40nw%40euAn%7DAyoA%7CsCagBftA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=rYtfIojIXwdhtd9RgwR7P6VGoPQ=) ### West End If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=977664051587067904) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496800-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496794-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496797-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496795-sanibel-historical-museum-and-village.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496033-southwest-coast-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=977663677668896768) ![Mid Island map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ivk%60Dfj%7EsNoU%7Bk%40sk%40m%5EsTlS_%5DeYmi%40%7B%5CiBiQvJ%7BUd%5B%7Be%40zP_e%40fTgRbLkPpq%40lLdi%40MnQEdb%40b%7E%40%7EWzn%40hZphArFzb%40b%40h%5DefC%60B&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=VxGJcF1rdvQCDBU5UqL_Xs8Jsy8=) ### Mid Island If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=977663677668896768) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/495000/495910-south-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496810-sanibel.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496815-sanibel.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496813-sanibel.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496031-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=977663465835589632) ![East End map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wkl%60DbmvsNsq%40kLxBsM%7EBFpByDtDqR%7D%40_DNoZaBqNm%40aNViE%7D%40uKyFcOVqExFeGpE%60A%7CDpDlFpN%7EYjj%40nOt_%40zc%40%60aAk%7B%40X&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hlweUqTn_teHrd_l720zC5CKvf4=) ### East End While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=977663465835589632) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496031-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496033-southwest-coast-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496099-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496100-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496067-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976658737) ![Beachview Country Club Estates map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_xi%60DnhzsN%7DF%7BKm%40qJo%60%40WcFgQsIGkFm%5BlPuInCdJrU%3Fh%40cBhAh%40vCwAve%40%7CjAuVF&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=01bhKNjFz-Z_Q0nxmzzaWzGMm0I=) ### Beachview Country Club Estates While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976658737) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976469368) ![Sanctuary map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Dct%60DjfqtNcl%40iNz%40%7D%5Ef%5DeBxrAodAbBcLfV%7DAbCzGkT%60OqDlf%40wIpR%7BHnXyHlIcf%40fByCzK&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=poR-ON5_hQI0xWhU_gQlcmdLxUw=) ### Sanctuary While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976469368) ## Top Murex Lakes Hotel Reviews ![DiamondHead Beach Resort](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "Clean rooms..Staff wonderfull..Food wonderful Mike in Maintenance went out of his way to help bring our groceries to our suite..Will be back next December " [](https://expedia.co.uk/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "Pink Shell was amazing. The room was awesome. The beach and pool were great. The food was wonderful. All in all this resort was perfect for our anniversary and we will definitely be back. " [](https://expedia.co.uk/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/81b75b6a_y.jpg) ### Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral 10/10 Excellent "EVERYTHING And EVERYONE were just wonderful. " [](https://expedia.co.uk/Fort-Myers-Hotels-Fairfield-Inn-Suites-By-Marriott-Ft-MyersCape-Coral.h129295.Hotel-Information) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Everything perfect" [](https://expedia.co.uk/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Great place." [](https://expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Matanzas Inn Bayside Resort and Marina](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/fc463bf9_y.jpg) ### Matanzas Inn Bayside Resort and Marina 10/10 Excellent "Will stay at your place again. Exceeded all of our expectations. Thank you Doug and Christine." [](https://expedia.co.uk/Fort-Myers-Hotels-Matanzas-Inn-Bayside-Resort-And-Marina.h2665085.Hotel-Information) ![Hyatt Vacation Club at Coconut Cove, Bonita Springs](https://images.trvl-media.com/lodging/1000000/1000000/991200/991114/fedffc57_y.jpg) ### Hyatt Vacation Club at Coconut Cove, Bonita Springs 10/10 Excellent "We books a 2 bedroom for our stay. The room was spectacular ! The deep soaker tub was a nice surprise we booked our stay about 2 months out and for 199 a night you can’t beat this place . The only small downside is that the main pool areas which is huge and includes a lazy river, closes at sundown. But definitely a 5 star stay." [](https://expedia.co.uk/Bonita-Springs-Hotels-Hyatt-Vacation-Club-At-Coconut-Cove.h991114.Hotel-Information) ![The Lighthouse Resort Inn & Suites](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3_y.jpg) ### The Lighthouse Resort Inn & Suites 10/10 Excellent "Great resort fun bar beautiful pool walkable area variety of restaurants and clean beach" [](https://expedia.co.uk/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/8158a459_y.jpg) ### Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway 10/10 Excellent "The breakfasts were phenomenal! Room was clean, shower was nice, friendly staff and bed really comfy!" [](https://expedia.co.uk/Fort-Myers-Beach-Hotels-Hampton-Inn-Suites-Fort-Myers-BeachSanibel-Gateway.h551886.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Murex Lakes hotel booking with Expedia? ### How much is the nightly rate at a Murex Lakes hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [3 Star Hotels in Sanibel ](https://www.expedia.co.uk/3Star-Sanibel-Hotels.s30-0-d9791.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Sanibel Captiva Island ](https://www.expedia.co.uk/4Star-Sanibel-Captiva-Island-Hotels.s40-0-d6326115.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Sanibel ](https://www.expedia.co.uk/4Star-Sanibel-Hotels.s40-0-d9791.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Sanibel Captiva Island ](https://www.expedia.co.uk/5Star-Sanibel-Captiva-Island-Hotels.s50-0-d6326115.Travel-Guide-Filter-Hotels) - [Hotels near Alison Hagerup Beach Park ](https://www.expedia.co.uk/Alison-Hagerup-Beach-Park-Hotels.0-l6182809-0.Travel-Guide-Filter-Hotels) - 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