Default HTG hotel image

Search Hotels in Murex Lakes, Sanibel

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
7 Aug - 9 Aug
Next weekend
14 Aug - 16 Aug

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Murex Lakes hotels

Property amenity

1. Island Inn

Island Inn
3.5 star property
West End, 0.5 mi from Murex Lakes
9.4 out of 10, Exceptional, (1,143 reviews)
"Great views, clean room, amazing beach and staff!!! Can't wait to come."
United States
Daniel
The price is £198
includes taxes & fees
23 Aug - 24 Aug
Island Inn
On the beach, white sand, snorkelling, surfing

2. Shalimar Beach Resort

Shalimar Beach Resort
3.5 star property
West End, 0.9 mi from Murex Lakes
9.8 out of 10, Exceptional, (75 reviews)
"Beautiful place! Would definitely stay again."
United States
Vickie
The price is £185
includes taxes & fees
30 Aug - 31 Aug
Shalimar Beach Resort
On the beach, sun-loungers, beach towels

3. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.3 mi from Murex Lakes
9.2 out of 10, Wonderful, (2,176 reviews)
"Beautiful beach, clean rooms, good service, excellent in house restaurant, Highly recommend!!"
United States
Nathan Paul
The price is £169
includes taxes & fees
16 Aug - 17 Aug
Sanibel Island Beach Resort
Deluxe Single Room | Living area | 55-inch Smart TV with cable channels, streaming services

4. The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 3.4 mi from Murex Lakes
9.8 out of 10, Exceptional, (62 reviews)
"Loved staying here, very clean"
United States
Liliana
The price is £129
includes taxes & fees
3 Sept - 4 Sept
The Anchor Inn
Garden

5. Kona Kai Motel

Kona Kai Motel
2.5 star property
Mid Island, 2.9 mi from Murex Lakes
9.0 out of 10, Wonderful, (1,005 reviews)
"Great place to stay and the staff was very helpful"
United States
Gregory John
The price is £137
includes taxes & fees
6 Aug - 7 Aug
Kona Kai Motel
Free daily buffet breakfast

6. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.8 mi from Murex Lakes
8.8 out of 10, Excellent, (1,008 reviews)
"Nice hotel, nice pool will go there again next time"
United States
Louis
The price is £74
includes taxes & fees
9 Aug - 10 Aug
Residence Inn by Marriott Fort Myers Sanibel
View from room

7. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
9.1 mi from Murex Lakes
8.2 out of 10, Very good, (1,289 reviews)
"Clean room, helpful staff an good breakfast"
United States
ALICIA
The price is £60
includes taxes & fees
17 Aug - 18 Aug
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Deluxe Suite (Second Floor Only) | Terrace/patio

8. Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
5 mi from Murex Lakes
9.6 out of 10, Exceptional, (162 reviews)
"Great little place. Could see the manatees from the dock. Super clean."
United States
Greg
The price is £149
includes taxes & fees
11 Aug - 12 Aug
Off the Charts Inn & Out Island Resort
Exterior

9. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
10.9 mi from Murex Lakes
9.2 out of 10, Wonderful, (1,008 reviews)
"Air conditioning is great, room is clean, staff is great, Breakfast is very good .."
United States
Lilia
The price is £72
includes taxes & fees
2 Sept - 3 Sept
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
View from property

10. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
6.8 mi from Murex Lakes
8.6 out of 10, Excellent, (1,010 reviews)
"The staff were amazing during our stay and it had beautiful view of the bay. Definitely a great stay!!"
United States
Sandra J
The price is £184
includes taxes & fees
17 Aug - 18 Aug
Marriott Sanibel Harbour Resort & Spa
2 outdoor pools

11. The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
9.1 mi from Murex Lakes
8.6 out of 10, Excellent, (1,745 reviews)
"great stay - only one nite, but was able to get there early and stay late.....worth the stop"
United States
james
The price is £102
includes taxes & fees
9 Aug - 10 Aug
The Lighthouse Resort Inn & Suites
Exterior

12. Sanibel Inn

Sanibel Inn
3.0 star property
East End, 3.9 mi from Murex Lakes
9.2 out of 10, Wonderful, (1,001 reviews)
"Gorgeous property! Beautiful, quiet beach. The room was huge and extremely clean. Wonderful place for families."
United States
Lisa
The price is £257
includes taxes & fees
2 Sept - 3 Sept
Sanibel Inn
Lobby

13. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
10.8 mi from Murex Lakes
8.8 out of 10, Excellent, (1,009 reviews)
"The friendliness of the staff and breakfast was great."
United States
Daveanand
The price is £67
includes taxes & fees
16 Aug - 17 Aug
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
Premium Cottage, Lanai, Garden View | Living area | Smart TV

14. Driftwood Inn

Driftwood Inn
4.0 star property
Mid Island, 3.4 mi from Murex Lakes
10.0 out of 10, Exceptional, (11 reviews)
"The cottage was well stocked with all we needed. It was also immaculate with a lovely garden. The beach was a 5 minute walk."
United States
Maureen
The price is £339
includes taxes & fees
4 Aug - 5 Aug
Driftwood Inn
Suite, 2 Bedrooms, Marina View | Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe

15. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
9.8 mi from Murex Lakes
9.0 out of 10, Wonderful, (1,002 reviews)
"Very nice hotel , beautiful location, lots of amenities"
United States
Marlies
The price is £146
includes taxes & fees
27 Aug - 28 Aug
The Westin Cape Coral Resort At Marina Village
Sun deck

16. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
9.7 mi from Murex Lakes
8.8 out of 10, Excellent, (1,003 reviews)
"Great room for the price and area"
United States
Desiree
The price is £73
includes taxes & fees
5 Aug - 6 Aug
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Exterior

17. THE Palmview AND Sandpiper Inns

THE Palmview AND Sandpiper Inns
3.5 star property
Mid Island, 3.4 mi from Murex Lakes
9.2 out of 10, Wonderful, (221 reviews)
"Horrible"
United States
Jailene
The price is £252
includes taxes & fees
15 Aug - 16 Aug
THE Palmview AND Sandpiper Inns
Floating Coconut Cottage Houseboat | Terrace/patio

18. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
10 mi from Murex Lakes
8.6 out of 10, Excellent, (1,002 reviews)
"Great place to stay"
United States
Rick
The price is £84
includes taxes & fees
11 Aug - 12 Aug
Latitude 26 Waterfront Resort & Marina
Grand Studio Suite, Kitchenette | Desk, laptop workspace, free WiFi, bed sheets

19. Lazy Cuckoo Inn

Lazy Cuckoo Inn
2.0 star property
10.4 mi from Murex Lakes
8.8 out of 10, Excellent, (295 reviews)
"Clean room, good location, easy check in instructions."
United States
Brooklyn
The price is £69
includes taxes & fees
6 Aug - 7 Aug
Lazy Cuckoo Inn
Exterior

20. Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 3 mi from Murex Lakes
8.6 out of 10, Excellent, (2,680 reviews)
"Clean room and beach view"
United States
Carla
The price is £354
includes taxes & fees
6 Aug - 7 Aug
Sundial Beach Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Murex Lakes

Find the best Murex Lakes areas for the activities you enjoy most.
A coastal scene with a lighthouse, beach, and ocean.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Dunes Golf and Tennis Club are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

A cyclist on a paved path alongside a road with cars, palm trees, and a liquor store sign.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Top Murex Lakes Hotel Reviews

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

10/10 Excellent
"Great hotel! Clean rooms, accommodates late arrivals!"
Bethany 1-night trip
Posted less than an hour ago
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Frequently asked questions

When is the best time to go to Murex Lakes?
The best time to visit Murex Lakes is during the dry season, from November to April, when the weather is consistently pleasant and ideal for outdoor activities.

During these months, the humidity is lower, and there's less chance of rain, making it great for exploring the natural beauty of the area. Temperatures are usually warm but comfortable, averaging around 20-25°C (68-77°F). This is an excellent time for couples looking to enjoy the region's scenic trails or water-based excursions without the discomfort of scorching heat or heavy downpours.

The shoulder months of May and October can also be good options, offering a balance of good weather and fewer crowds. While there's a slightly higher chance of rain or humidity, you'll often find better value on accommodation and a more relaxed pace.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Murex Lakes.
How much is the nightly rate at a Murex Lakes hotel?
Hotel prices in Murex Lakes often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia