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Check prices for these dates

This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

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Our top choices for Murex Lakes hotels

A beach with a view of the ocean and a sunset.

1. Island Inn

Island Inn
3.5 star property
West End, 0.5 mi from Murex Lakes
9.4 out of 10, Exceptional, (1,156 reviews)
"Great location"
United States
Nicole
The price is £169
includes taxes & fees
29 Sept - 30 Sept
Island Inn
A wooden boardwalk leading to a beach with clear skies and calm waters.

2. Shalimar Beach Resort

Shalimar Beach Resort
3.5 star property
West End, 0.9 mi from Murex Lakes
9.8 out of 10, Exceptional, (98 reviews)
"This hotel was absolutely wonderful. I will book here again."
United States
PATRICIA
The price is £187
includes taxes & fees
27 Sept - 28 Sept
Shalimar Beach Resort
A beach with a variety of seashells and pebbles.

3. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.3 mi from Murex Lakes
9.2 out of 10, Wonderful, (2,315 reviews)
"We had a great time, location was perfect"
United States
Jill
The price is £170
includes taxes & fees
4 Oct - 5 Oct
Sanibel Island Beach Resort
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

4. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.8 mi from Murex Lakes
8.8 out of 10, Excellent, (1,008 reviews)
"The hotel was in a great location, very clean and had great breakfast options."
United States
jennifer
The price is £72
includes taxes & fees
24 Sept - 25 Sept
Residence Inn by Marriott Fort Myers Sanibel
A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

5. Casa Ybel Resort

Casa Ybel Resort
2.5 star property
Ybel, 1.9 mi from Murex Lakes
8.8 out of 10, Excellent, (432 reviews)
"Loved the large, condo-size rooms. Loved our ocean view and wait staff at pool was great. I would definitely stay there again."
United States
Karen Elizabeth
The price is £212
includes taxes & fees
27 Sept - 28 Sept
Casa Ybel Resort

6. The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 3.4 mi from Murex Lakes
9.8 out of 10, Exceptional, (72 reviews)
"10/10would stay here again"
United States
Jamie
The price is £131
includes taxes & fees
27 Sept - 28 Sept
The Anchor Inn
A pathway flanked by palm trees and wooden buildings with thatched roofs.

7. Kona Kai Motel

Kona Kai Motel
2.5 star property
Mid Island, 2.9 mi from Murex Lakes
9.0 out of 10, Wonderful, (1,001 reviews)
"Good location"
United States
Presley
The price is £138
includes taxes & fees
24 Sept - 25 Sept
Kona Kai Motel
A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

8. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
9.7 mi from Murex Lakes
9.0 out of 10, Wonderful, (1,000 reviews)
"Perfect hotel"
United States
Ana
The price is £69
includes taxes & fees
24 Sept - 25 Sept
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

9. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
9.1 mi from Murex Lakes
8.2 out of 10, Very good, (1,355 reviews)
"Perfect stay"
United States
Jorge
The price is £59
includes taxes & fees
29 Sept - 30 Sept
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

10. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
10.9 mi from Murex Lakes
9.2 out of 10, Wonderful, (1,003 reviews)
"Very clean and comfortable hotel! Great breakfast too!"
United States
Gigette
The price is £79
includes taxes & fees
22 Oct - 23 Oct
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

11. Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
5 mi from Murex Lakes
9.6 out of 10, Exceptional, (164 reviews)
"Very comfortable and convenient location!"
United States
Lisa
The price is £137
includes taxes & fees
24 Sept - 25 Sept
Off the Charts Inn & Out Island Resort
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

12. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
10.8 mi from Murex Lakes
8.8 out of 10, Excellent, (1,010 reviews)
"This was close to our destination and always clean and friendly folks."
United States
Brandon
The price is £64
includes taxes & fees
29 Sept - 30 Sept
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
An outdoor seating area with wicker chairs and a central table, surrounded by lush greenery and palm trees.

13. THE Palmview AND Sandpiper Inns

THE Palmview AND Sandpiper Inns
3.5 star property
Mid Island, 3.4 mi from Murex Lakes
9.2 out of 10, Wonderful, (225 reviews)
"Quaint beautiful place we enjoyed our stay very much"
United States
JACQUELINE
The price is £165
includes taxes & fees
12 Oct - 13 Oct
THE Palmview AND Sandpiper Inns
A spacious living room with a grey sofa, striped armchair, and a woven coffee table. Large windows offer a view of a tropical garden.

14. Driftwood Inn

Driftwood Inn
4.0 star property
Mid Island, 3.4 mi from Murex Lakes
10.0 out of 10, Exceptional, (11 reviews)
"This was our second stay at Driftwood Inn and we enjoyed it as much this time as the last! Property is immaculately cleaned, comfortable and has everything we need. The beach is a short walk away and the included cart, umbrellas and beach chairs make it easy to enjoy your time relaxing in the sun. Highly recommend this property for your beach time!"
United States
Heather
The price is £351
includes taxes & fees
29 Sept - 30 Sept
Driftwood Inn
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

15. The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
9.1 mi from Murex Lakes
8.6 out of 10, Excellent, (1,792 reviews)
"Very close to the Beach. Pool is nice and bar is outstanding"
United States
Sherrie
The price is £91
includes taxes & fees
30 Sept - 1 Oct
The Lighthouse Resort Inn & Suites
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

16. Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
8.8 mi from Murex Lakes
9.4 out of 10, Exceptional, (1,006 reviews)
"Very nice place for short stay. If you like a quiet environment, this is your best choice."
United States
selma
The price is £166
includes taxes & fees
24 Sept - 25 Sept
Best Western Plus Beach Resort
A balcony with a wicker sofa, a yellow table, and a potted plant.

17. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
10 mi from Murex Lakes
8.6 out of 10, Excellent, (1,002 reviews)
"Definitely would stay again"
United States
Sebastian
The price is £81
includes taxes & fees
24 Sept - 25 Sept
Latitude 26 Waterfront Resort & Marina
A beach view with rows of empty wine glasses lined up on a balcony.

18. Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
9.3 mi from Murex Lakes
8.8 out of 10, Excellent, (2,042 reviews)
"Great place to stay!!"
United States
ROBERT
The price is £106
includes taxes & fees
30 Sept - 1 Oct
Lani Kai Beachfront Resort
A pool area with lounge chairs and umbrellas, a beach with umbrellas and lounge chairs, and palm trees.

19. Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 3 mi from Murex Lakes
8.6 out of 10, Excellent, (2,701 reviews)
"Excellent place for children"
United States
Jaime E
The price is £332
includes taxes & fees
24 Sept - 25 Sept
Sundial Beach Resort & Spa
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

20. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
6.8 mi from Murex Lakes
8.6 out of 10, Excellent, (1,003 reviews)
"Very clean resort; nice that beach chairs and umbrella available; good location"
United States
Charles
The price is £212
includes taxes & fees
6 Oct - 7 Oct
Marriott Sanibel Harbour Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Murex Lakes

Find the best Murex Lakes areas for the activities you enjoy most.
A coastal scene with a lighthouse, beach, and ocean.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

A street lined with palm trees and a sign for Periwinkle Place Shops.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

A beach with clear turquoise water, a sandy shore, and a weathered driftwood structure.

Gulf Shores

When in Gulf Shores, you can plan a visit to Bowman's Beach and J. N. Ding Darling National Wildlife Refuge, some noteworthy sights in the nearby area.

Top Murex Lakes Hotel Reviews

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

10/10 Excellent
"We had a great time!"
Giovanni 2-night trip
Posted 2 hours ago
The Lighthouse Resort Inn & Suites

Frequently asked questions

When is the best time to go to Murex Lakes?
The best time to visit Murex Lakes is during the dry season, from November to April, when the weather is consistently pleasant and ideal for outdoor activities.

During these months, the humidity is lower, and there's less chance of rain, making it great for exploring the natural beauty of the area. Temperatures are usually warm but comfortable, averaging around 20-25°C (68-77°F). This is an excellent time for couples looking to enjoy the region's scenic trails or water-based excursions without the discomfort of scorching heat or heavy downpours.

The shoulder months of May and October can also be good options, offering a balance of good weather and fewer crowds. While there's a slightly higher chance of rain or humidity, you'll often find better value on accommodation and a more relaxed pace.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Murex Lakes.
How much is the nightly rate at a Murex Lakes hotel?
Hotel prices in Murex Lakes often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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