Sanibel adults only hotels from £71

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Top Adults only hotels in Sanibel

Comfort Suites Fort Myers East I-75
2.5 out of 5
9455 Old Luckett Drive, Building A, Fort Myers, FL
The price is £77 per night from 5 Aug to 6 Aug
£77
5 Aug - 6 Aug
includes taxes & fees
9.6/10 Exceptional! (237 reviews)
"My experience here was a 10/10.."

Reviewed on 28 Jul 2025

Comfort Suites Fort Myers East I-75
Tarpon Tale Inn
3 out of 5
367 Periwinkle Way, Sanibel, FL
9.6/10 Exceptional! (388 reviews)
"Tarpon Tale Inn is a hidden treasure! If you want a quiet getaway on Sanibel Island with quick access to the beach, a private patio and grill, access to bicycles, an outdoor hot/cold shower, a shell washing station, and beach chairs/umbrella/wagon - this is it! The owner, Joe, has an eye for detail ..."

Reviewed on 19 Jul 2025

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Tarpon Tale Inn
Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!
Sanibel, FL
The price is £203 per night from 7 Aug to 8 Aug
£203
7 Aug - 8 Aug
includes taxes & fees
9.6/10 Exceptional! (44 reviews)
"We have always loved our stay here! Very clean and charming. And Sanibel is lovely! We will be back, for sure!"

Reviewed on 16 Jul 2025

Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!
Luxury Villa "Lighthouse" Across from the Beach
Sanibel, FL
The price is £364 per night from 1 Sept to 2 Sept
£364
1 Sept - 2 Sept
includes taxes & fees
9.6/10 Exceptional! (32 reviews)
Rudolph family
"We had a great time while in Sanibel. The property was very nice and close to our beloved beach."

Reviewed on 10 Jul 2025

Luxury Villa "Lighthouse" Across from the Beach
Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 out of 5
14567 GLOBAL PARKWAY, Fort Myers, FL
The price is £73 per night from 31 Aug to 1 Sept
£73
31 Aug - 1 Sept
includes taxes & fees
9.4/10 Exceptional! (988 reviews)
"I had a last-minute flight cancellation and needed a convenient place to stay near the airport. After some searching, I came across this hidden gem! The hotel was clean, quiet, and welcoming, with a friendly and helpful staff. One of the standout features was the airport shuttle service, which starts ..."

Reviewed on 28 Jul 2025

Holiday Inn Express & Suites Fort Myers Airport by IHG
Island Inn
3.5 out of 5
3111 W Gulf Dr, Sanibel, FL
The price is £194 per night from 11 Aug to 12 Aug
£194
11 Aug - 12 Aug
includes taxes & fees
9.4/10 Exceptional! (1,085 reviews)
"We stayed in a room with an absolutely breathtaking view, the perfect way to start and end each day with the sound of the ocean. The front desk service at check-in and check-out was fantastic – friendly, welcoming, and efficient. The beach is spectacular – peaceful, clean, and ideal for relaxing ..."

Reviewed on 28 Jul 2025

Island Inn
La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.
3 out of 5
28600 Trails Edge Blvd, Bonita Springs, FL
The price is £71 per night from 23 Aug to 24 Aug
£71
23 Aug - 24 Aug
includes taxes & fees
9/10 Wonderful! (1,108 reviews)
"The suite was comfortable and spacios."

Reviewed on 3 Aug 2025

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.
Newly remodeled Parakeet cottage! Walking distance to beach, restaurants, shops!
Sanibel, FL
The price is £206 per night from 9 Aug to 10 Aug
£206
9 Aug - 10 Aug
includes taxes & fees
9/10 Wonderful! (63 reviews)
Great Communication
"Sweet liitle efficiency cottage. Excellent air conditioning. I was really impressed with how responsive they are when asking questions about visitor parking and such. Bikes were awesome and location was great. If we come back to Sanibel we will stay at Parrot nest again."

Reviewed on 5 Jul 2025

Newly remodeled Parakeet cottage! Walking distance to beach, restaurants, shops!
Sanibel Island Beach Resort
3 out of 5
1231 Middle Gulf Dr, Sanibel, FL
The price is £207 per night from 25 Aug to 26 Aug
£207
25 Aug - 26 Aug
includes taxes & fees
9/10 Wonderful! (1,245 reviews)
"Loved location on beach and pool. Very clean nice restaurant on site. Didn't like pool closed too early."

Reviewed on 1 Aug 2025

Sanibel Island Beach Resort
Sanibel Siesta on the Beach
2 out of 5
1246 Fulgur Street, Sanibel, FL
The price is £588 per night from 5 Aug to 6 Aug
£588
5 Aug - 6 Aug
includes taxes & fees
Sanibel Siesta on the Beach
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find Romantic Hotels in Sanibel

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

1451 Middle Gulf Drive, Sanibel, FL
The price is £373 per night from 5 Aug to 6 Aug
£373
5 Aug - 6 Aug
includes taxes & fees
8.6/10 Excellent! (2,572 reviews)

Frequently Asked Questions

How can I find the best adults only resorts in Sanibel?

The best adults only resort for you is deeply personal. First off, decide what you want from your dream holiday, then use our filters to bring it to life. Find resorts with hot tubs, spas and incredible views, then check out the reviews to see how other guests enjoyed their stay.

How much does a Sanibel adults-only hotel cost?

With Expedia, you can find adults only hotels from £71 to per night. Prices and availability are subject to change. Additional terms may apply.

How can I find an adults only all-inclusive holiday in Sanibel?

It’s simple. Just select the all-inclusive filter to find the best resorts where you can eat, drink and holiday to your heart’s content.

What can I expect from Sanibel 5-star all-inclusive adults only hotels?

Luxury comes as standard in the 5-star resorts of Sanibel. Step into spotless surroundings, stellar service and all the amenities your heart desires, from spas and pools to casinos and cocktail bars.

Why should I book a Sanibel adults only hotel with entertainment?

When you book an adult only hotel with entertainment, pack your bags to get dolled up for the very best of comedy, cabaret, music, magic and much more – all just steps from your room.

How can I find the best deals on adults only resorts in Sanibel?

To find amazing deals in Sanibel and for a quieter experience, book your holiday in . The more flexible you can be with your dates, the better your chances are of getting a fantastic wallet-friendly deal. You can always check out our latest cheap deals for a little inspiration.

Do adults only hotels in Sanibel offer free cancellation?

Some adults only hotels here offer free cancellation. Some don’t. It’s always best to check before you book. You can filter by free cancellation and pay later options to find resorts with that extra flexibility you want.

Why should I book my adults only resort in Sanibel with Expedia?

At Expedia, we put everything you need to book your dream trip in one place. With a vast selection of incredible adult only accommodation at your fingertips, all that’s left to do is set your sights on what’s right for you.