A paved pathway lined with tropical plants and palm trees, leading to a gazebo and a fountain.

Search Adults Only Resorts & Hotels in Sanibel

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on Sanibel Adults Only Resorts & Hotels

Tonight
23 Sept - 24 Sept
Tomorrow
24 Sept - 25 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct
No exact matches found, but these alternatives could be just right

Recommended hotels in Sanibel

1. Sanibel Island Beach Resort

Sanibel Island Beach Resort
Mid Island
United States
Jill
£170
includes taxes & fees
4 Oct - 5 Oct
Sanibel Island Beach Resort

2. The Anchor Inn

The Anchor Inn
Mid Island
United States
Jamie
£131
includes taxes & fees
27 Sept - 28 Sept
The Anchor Inn

3. Sanibel Island condo - Close to the beach - Colony Inn 01

Sanibel Island condo - Close to the beach - Colony Inn 01
East End
United States
Christopher A.
£223
includes taxes & fees
27 Sept - 28 Sept
Sanibel Island condo - Close to the beach - Colony Inn 01

4. Sanibel Inn

Sanibel Inn
East End
United States
William
£300
includes taxes & fees
28 Sept - 29 Sept
Sanibel Inn

5. Kona Kai Motel

Kona Kai Motel
Mid Island
United States
Presley
£138
includes taxes & fees
24 Sept - 25 Sept
Kona Kai Motel

6. THE Palmview AND Sandpiper Inns

THE Palmview AND Sandpiper Inns
Mid Island
United States
JACQUELINE
£165
includes taxes & fees
12 Oct - 13 Oct
THE Palmview AND Sandpiper Inns

7. Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!

Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!
East End
United States
Stephen
£236
includes taxes & fees
24 Sept - 25 Sept
Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!

8. Anchor Inn & Cottage - King Pondview Room

Anchor Inn & Cottage - King Pondview Room
Mid Island
United States
Nicole K.
£119
includes taxes & fees
27 Sept - 28 Sept
Anchor Inn & Cottage - King Pondview Room

9. Newly remodeled Parakeet cottage! Walking distance to beach, restaurants, shops!

Newly remodeled Parakeet cottage! Walking distance to beach, restaurants, shops!
East End
United States
Eric W.
£236
includes taxes & fees
24 Sept - 25 Sept
Newly remodeled Parakeet cottage! Walking distance to beach, restaurants, shops!

10. The Lovebird-sleeps 3! Great value on Sanibel-walk to dining, shops and Historic East End Lighthouse

The Lovebird-sleeps 3! Great value on Sanibel-walk to dining, shops and Historic East End Lighthouse
East End
United States
Trina S.
£266
includes taxes & fees
24 Sept - 25 Sept
The Lovebird-sleeps 3! Great value on Sanibel-walk to dining, shops and Historic East End Lighthouse
View all properties

Find out more about Sanibel

Discover top Sanibel attractions

Sanibel, Florida, is a paradise of unique experiences perfect for discerning travellers. Begin your adventure at the J.N. "Ding" Darling National Wildlife Refuge, where you can explore lush mangroves and spot diverse wildlife, including manatees and alligators, from the comfort of your own kayak. After a morning of nature immersion, head to the renowned Sanibel Island Lighthouse, a historic landmark offering picturesque views of the Gulf and the chance to enjoy a quiet beach picnic. For families, the Bailey-Matthews National Shell Museum is a must-visit, showcasing the stunning variety of shells found on the island, with engaging exhibits that will captivate children and adults alike. Don’t miss the opportunity to indulge in fresh seafood at local eateries like The Bubble Room, where you can enjoy a meal surrounded by eclectic decor and mouth-watering desserts. For accommodation, consider staying in the tranquil area of West Gulf Drive, where beachfront hotels offer direct access to sandy shores and breathtaking sunsets. Here, you can unwind in luxury while enjoying attentive service that caters to your every need, making your stay as relaxing as the island itself.

Find the best adults only resorts & hotels in Sanibel

For those seeking a tranquil escape free from the bustle of family-friendly environments, Sanibel, Florida, offers hotels that cater exclusively to adult guests. Here are two top choices for a serene getaway.Sunshine Island Inn

  • Why it's great for an adults only getaway: Sunshine Island Inn is an idyllic retreat for adult travellers looking for a peaceful escape, an impressive guest review rating of 9.0. This charming hotel offers exclusive adults-only amenities, ensuring a tranquil environment where guests can unwind. With a delightful outdoor pool and a sandy beach just a short walk away, it’s perfect for those wanting to relax in the sun without distractions.
  • Other amenities: The inn features comfortable rooms equipped with kitchenettes, including an oven, microwave, and refrigerator, ideal for preparing light meals during your stay. Guests can enjoy the outdoor space with beach towels and umbrellas provided for a day by the water. Additional conveniences include free self-parking, air conditioning, and a patio area for enjoying peaceful evenings under the stars.
  • Nearby attractions: Sanibel Island Southern Beach - 1.2 km, Sanibel Moorings Botanical Gardens - 0.6 km, Periwinkle Way - 1.7 km

Top Sanibel Hotel Reviews

Frequently asked questions

How much do adults-only hotels in Sanibel cost?
Costs for an adults-only hotel in Sanibel may change due to, among other things, the star rating and amenities provided by the hotel. Whatever your budget, you'll discover a grown-up getaway where you'll be able to breathe easy and relax with Expedia.

Explore a world of travel with Expedia