Title: TOP Adults Only Resorts & Hotels in Sanibel, FL for 2025 | Expedia.co.uk [Sanibel Travel Guide](https://expedia.co.uk/Sanibel.dx9791)[Hotels in Sanibel](https://expedia.co.uk/Sanibel-Hotels.d9791.Travel-Guide-Hotels)[Holiday Rentals in Sanibel](https://expedia.co.uk/Sanibel-Holiday-Rentals.d9791.Travel-Guide-HolidayRentals)[Flights to Sanibel](https://expedia.co.uk/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.co.uk/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Sanibel Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Sanibel.d9791.Car-Hire-Guide)[Sanibel Holidays](https://expedia.co.uk/Sanibel.d9791.Holidays-City-Breaks) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/495000/495976-southwest-coast-florida.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Adults Only Resorts & Hotels in Sanibel ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Sanibel Adults Only Resorts & Hotels Tonight [5 Oct - 6 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=9791&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [6 Oct - 7 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=9791&startDate=2025-10-06&endDate=2025-10-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=9791&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=9791&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Sanibel Adults Only Resorts & Hotels We don't have any properties that match your exact search [See all properties in Sanibel](https://expedia.co.uk/Hotel-Search?startDate=2025-10-19&endDate=2025-10-20®ionId=9791&adults=2) ## Recommended hotels in Sanibel ![Property amenity](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/w2868h1920x12y0-118022ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/6a1456e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking (Upgrade) | Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/3b030475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/54b129e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Fort Myers East I-75 Fort Myers 9.6/10 Exceptional (282) "Would definitely stay here again. Staff was very friendly. " £55 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Fort-Myers-Hotels-Comfort-Suites.h109299203.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99320000/99317000/99316921/w2868h1920x12y0-d01c6578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Suite, Multiple Beds, Non Smoking | 1 bedroom, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/100000000/99320000/99317000/99316921/8abf7fae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99320000/99317000/99316921/0715c46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/100000000/99320000/99317000/99316921/512e2c13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Fort Myers East I-75 Fort Myers 9.6/10 Exceptional (165) "Great location (for what I needed to do), clean rooms, quiet area. " £77 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Fort-Myers-Hotels-Mainstay-Suites-Fort-Myers.h99316921.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/49000000/48990000/48980100/48980077/98e32444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/49000000/48990000/48980100/48980077/2da48eb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/49000000/48990000/48980100/48980077/5658994c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/49000000/48990000/48980100/48980077/e26fbeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Fort Myers Airport by IHG Daniels Corridor 9.6/10 Exceptional (1002) "Great place to stay." £77 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Fort-Myers-Southeast.h48980077.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8080000/8078500/8078470/af9b7573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/9000000/8080000/8078500/8078470/53376a30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Balcony (Eff 1-5, 2-2, 2-5, 3-5, 3-1, 1-2H/C) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/9000000/8080000/8078500/8078470/c7cabc5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Room, Balcony (Room 1-1) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/9000000/8080000/8078500/8078470/4b2edb1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kona Kai Motel Sanibel 9.0/10 Wonderful (931) "This a a beautiful location. Quite a unique experience for a hotel, and absolutely somewhere I'll be back. Not pet friendly, but thats okay. The whole setup is just the perfect island vacation location. I literally cannot say enough good stuff about this hotel." £135 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Sanibel-Hotels-Kona-Kai-Motel.h8078470.Hotel-Information) ![Luxury Suite, Sea View | Beach/ocean view](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/57dffb5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gulfview Studio | Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/8530c714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Sea View | Balcony view](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/1fdb20ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Sea View | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/2000000/1510000/1509800/1509747/e943aa9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Island Inn Sanibel 9.4/10 Exceptional (1110) "A great place to enjoy the beach. Beautiful sunsets, We will definitely be back to Island Inn. Thanks for a great vacation!!!" £181 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Fort-Myers-Hotels-Island-Inn.h1509747.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/38000000/37780000/37773900/37773827/f4d4a2d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37780000/37773900/37773827/7d50ec16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/38000000/37780000/37773900/37773827/23aec13d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37780000/37773900/37773827/03073880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coastal Chic Cottage "Sandpiper" minutes to the beach! Free bikes Tradewinds 9.0/10 Wonderful (23) "Loved our stay at the cottage. It was a perfect getaway for 2. Short walk to a quiet beach. Convenient to restaurants and Ding Darling.We will be back!" £301 includes taxes & fees 10 Oct - 11 Oct [](https://www.expedia.co.uk/Sanibel-Hotels-Coastal-Chic-Cottage-Sandpiper-Minutes-To-The-Beach-Free-Bikes-JULY-SAVINGS.h37773827.Hotel-Information) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/54000000/53880000/53878700/53878673/b1b22c4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/54000000/53880000/53878700/53878673/37b438ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/54000000/53880000/53878700/53878673/f00a123e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/54000000/53880000/53878700/53878673/c2c3a477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Newly remodeled Parakeet cottage! Walking distance to beach, restaurants, shops! Sanibel 9.2/10 Wonderful (68) "Lovely and clean little place. They have bikes you can use to get around. The island has a great bike/walking trail. " £245 includes taxes & fees 11 Oct - 12 Oct [](https://www.expedia.co.uk/Sanibel-Hotels-Newly-Remodeled-Parakeet-Cottage-Walking-Distance-To-Beach.h53878673.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun-loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/6b3a0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/2ab8abc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/aa9b23b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Island Beach Resort Sanibel 9.0/10 Wonderful (1325) "Excellent stay great staff and excellent location. " £168 includes taxes & fees 27 Oct - 28 Oct [](https://www.expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9780000/9773200/9773153/dd452d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 1 Bedroom, Kitchen (Captain's Cottage) | Living area | 50-inch flat-screen TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/10000000/9780000/9773200/9773153/1ae03dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach nearby, white sand, sun-loungers, beach umbrellas](https://images.trvl-media.com/lodging/10000000/9780000/9773200/9773153/b9b045b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/10000000/9780000/9773200/9773153/5025e743.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tarpon Tale Inn Sanibel 9.6/10 Exceptional (390) "This is the ideal spot for a beach vacation. The property is convenient, clean, and full of amenities like free bicycles. Owner was a very gracious host. Thoroughly recommend!" £189 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Fort-Myers-Hotels-Tarpon-Tale-Inn.h9773153.Hotel-Information) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37780000/37774200/37774142/16efd129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37780000/37774200/37774142/bc44f5f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37780000/37774200/37774142/5676ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/38000000/37780000/37774200/37774142/6c071a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel-Style on the East End! Walk to restaurants and the lighthouse. NEW! Sanibel 9.6/10 Exceptional (46) "Proximity to things to do on the island was great!" £230 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Sanibel-Hotels-Sanibel-Style-On-The-East-End-Walk-To-Restaurants.h37774142.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-19&endDate=2025-10-20®ionId=9791&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Sanibel ### Discover top Sanibel attractions Sanibel, Florida, is a paradise of unique experiences perfect for discerning travellers. Begin your adventure at the J.N. "Ding" Darling National Wildlife Refuge, where you can explore lush mangroves and spot diverse wildlife, including manatees and alligators, from the comfort of your own kayak. After a morning of nature immersion, head to the renowned Sanibel Island Lighthouse, a historic landmark offering picturesque views of the Gulf and the chance to enjoy a quiet beach picnic. For families, the Bailey-Matthews National Shell Museum is a must-visit, showcasing the stunning variety of shells found on the island, with engaging exhibits that will captivate children and adults alike. Don’t miss the opportunity to indulge in fresh seafood at local eateries like The Bubble Room, where you can enjoy a meal surrounded by eclectic decor and mouth-watering desserts. For accommodation, consider staying in the tranquil area of West Gulf Drive, where beachfront hotels offer direct access to sandy shores and breathtaking sunsets. Here, you can unwind in luxury while enjoying attentive service that caters to your every need, making your stay as relaxing as the island itself. ### Find the best adults only resorts & hotels in Sanibel For those seeking a tranquil escape free from the bustle of family-friendly environments, Sanibel, Florida, offers hotels that cater exclusively to adult guests. Here are two top choices for a serene getaway. [Sunshine Island Inn](https://www.expedia.co.uk/Fort-Myers-Hotels-Sunshine-Island-Inn.h9059583.Hotel-Information) - **Why it's great for an adults only getaway:** Sunshine Island Inn is an idyllic retreat for adult travellers looking for a peaceful escape, an impressive guest review rating of 9.0. This charming hotel offers exclusive adults-only amenities, ensuring a tranquil environment where guests can unwind. With a delightful outdoor pool and a sandy beach just a short walk away, it’s perfect for those wanting to relax in the sun without distractions. - **Other amenities:** The inn features comfortable rooms equipped with kitchenettes, including an oven, microwave, and refrigerator, ideal for preparing light meals during your stay. Guests can enjoy the outdoor space with beach towels and umbrellas provided for a day by the water. Additional conveniences include free self-parking, air conditioning, and a patio area for enjoying peaceful evenings under the stars. - **Nearby attractions:** Sanibel Island Southern Beach - 1.2 km, Sanibel Moorings Botanical Gardens - 0.6 km, Periwinkle Way - 1.7 km ## Top Sanibel Hotel Reviews ## Frequently asked questions ### How much do adults-only hotels in Sanibel cost? > Costs for an adults-only hotel in Sanibel may change due to, among other things, the star rating and amenities provided by the hotel. 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