A paved pathway lined with tropical plants and palm trees, leading to a gazebo and a fountain.

Search Boutique Hotels in Sanibel

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on Sanibel Boutique Hotels

Tonight
16 Sept - 17 Sept
Tomorrow
17 Sept - 18 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept
No exact matches found, but these alternatives could be just right

Recommended hotels in Sanibel

1. Sanibel Island Beach Resort

Sanibel Island Beach Resort
Mid Island
United States
Neva
£168
includes taxes & fees
6 Oct - 7 Oct
Sanibel Island Beach Resort

2. Sanibel Inn

Sanibel Inn
East End
United States
William
£290
includes taxes & fees
13 Oct - 14 Oct
Sanibel Inn

3. The Anchor Inn

The Anchor Inn
Mid Island
United States
Jamie
£133
includes taxes & fees
4 Oct - 5 Oct
The Anchor Inn

4. THE Palmview AND Sandpiper Inns

THE Palmview AND Sandpiper Inns
Mid Island
United States
JACQUELINE
£163
includes taxes & fees
12 Oct - 13 Oct
THE Palmview AND Sandpiper Inns

5. Kona Kai Motel

Kona Kai Motel
Mid Island
United States
Presley
£137
includes taxes & fees
17 Sept - 18 Sept
Kona Kai Motel

6. Anchor Inn & Cottage - King Pondview Room

Anchor Inn & Cottage - King Pondview Room
Mid Island
United States
Nicole K.
£126
includes taxes & fees
4 Oct - 5 Oct
Anchor Inn & Cottage - King Pondview Room

7. Sanibel Island 1BR Walk to Beach - Colony Inn 05

Sanibel Island 1BR Walk to Beach - Colony Inn 05
East End
United States
Michele W.
£236
includes taxes & fees
17 Sept - 18 Sept
Sanibel Island 1BR Walk to Beach - Colony Inn 05

8. Stunning Queen Deluxe Suite close to Beaches, Restaurants, Shopping!

Stunning Queen Deluxe Suite close to Beaches, Restaurants, Shopping!
Mid Island
United States
Amanda M.
£136
includes taxes & fees
21 Sept - 22 Sept
Stunning Queen Deluxe Suite close to Beaches, Restaurants, Shopping!

9. Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!

Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!
East End
United States
Stephen
£234
includes taxes & fees
20 Sept - 21 Sept
Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!

10. The Lovebird-sleeps 3! Great value on Sanibel-walk to dining, shops and Historic East End Lighthouse

The Lovebird-sleeps 3! Great value on Sanibel-walk to dining, shops and Historic East End Lighthouse
East End
United States
Trina S.
£263
includes taxes & fees
26 Sept - 27 Sept
The Lovebird-sleeps 3! Great value on Sanibel-walk to dining, shops and Historic East End Lighthouse
View all properties

Top Sanibel Hotel Reviews

Kona Kai Motel

Kona Kai Motel

10/10 Excellent
"I stayed at this motel and absolutely loved it. It was very private, it was very peaceful and very well maintained. I would definitely recommend staying here, and I will be returning."
Jennifer 2-night trip
Posted 20 hours ago
Kona Kai Motel

Frequently asked questions

What's there to see and do in Sanibel?
Visitors speak positively about this destination's breathtaking beach views, breathtaking sunsets and beautiful island views. Activities and attractions to experience around Sanibel include Key West Express, Sanibel Historical Museum and Village and Sanibel Island Northern Beach. While you're here, you might also like to explore more of the area and take in additional sights like Sanibel Island Lighthouse, Periwinkle Way and Sanibel Island Southern Beach.
What kind of weather should I plan for when I travel to Sanibel?
Getting an idea of what to expect from the weather in Sanibel will help you enjoy your stay to the fullest. The hottest months are usually August and July, with an average temperature of 28°C, while the coldest months are January and February, with an average of 20°C. The rainiest months in Sanibel are August, September, July and June, with each month seeing an average of 219 mm of rainfall.
What's the best way to get to my boutique hotel in Sanibel?
You have a few options for getting to and around Sanibel. The closest major airport is Fort Myers, FL (RSW-Southwest Florida Intl.), which is located 17.4 mi (28 km) from the heart of the city. If you'd like to explore around the area, you may want to rent a car for your trip.

Explore a world of travel with Expedia