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Holidays to Cayo Guillermo

Accommodation, flights, car rentals, things to do and more - for your holiday in Cayo Guillermo choose Expedia! Find everything you need to organize your trip to Cayo Guillermo in one place. Enter your dates in the search bar above or scroll to our top deals below!

Top flight + hotel deals in Cayo Guillermo

Trump National Doral Miami
Hotel St Augustine
Nautilus by Arlo
The L Hotel
National Hotel, An Adult Only Oceanfront Resort
Beacon Hotel South Beach

Top Hotel Deals

Iberostar Daiquirí
Iberostar Daiquirí
4 out of 5
Cayo Guillermo, Jardines del Rey, Moron Ciego de Avila, Cayo Guillermo, Ciego de Avila

Nestled on the beach, this Cayo Guillermo resort is 0.1 mi (0.1 km) from Cayo Guillermo Beach and 1.4 mi (2.3 km) from Cayo Guillermo Marina. Cayo Coco Beach ...

3.3/5 (41 reviews)

"The location of the hotel, staff, food and entertainment are great. We felt it’s a well designed hotel (Believe just over 300 rooms) as it never felt overcrowded nor overlooked. The staff are wonderfully helpful and friendly and plenty around."…"

Reviewed on 2 Mar 2020

Iberostar Daiquirí
Hotel Grand Muthu Cayo Guillermo
Hotel Grand Muthu Cayo Guillermo
3.5 out of 5
Cayo Guillermo, Cayo Guillermo, Ciego de Avila

Situated near the beach, this hotel is 0.4 mi (0.6 km) from Cayo Guillermo Beach and 2.4 mi (3.9 km) from Cayo Guillermo Marina. Cayo Coco Beach is 23 mi (37 ...

Hotel Grand Muthu Cayo Guillermo
Club Cayo Guillermo - All Inclusive
Club Cayo Guillermo - All Inclusive
3.5 out of 5
Jardines del Rey, Cayo Guillermo, Ciego de Avila

Located in Cayo Guillermo, this beachfront resort is in a regional park and within 1 mi (2 km) of Cayo Guillermo Beach and Cayo Guillermo Marina. Cayo Coco Beach ...

3/5 (1 review)
Так себе

"В целом неплохо. Отель вроде хороший но номера грязные и убитые. Кормят нормально. На пляже водоросли"…"

Reviewed on 27 Jan 2020

Club Cayo Guillermo - All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cayo Guillermo Beach Holiday

Escape the stresses of daily life and unwind on your Cayo Guillermo holiday. There's nothing more rejuvenating than the salty sea air and the soothing sound of waves breaking onto the shore. Organise your trip to Cayo Guillermo the quick and easy way by booking one of our Cayo Guillermo holiday packages. Many people decide to stay near Cayo Guillermo Beach, a local highlight just 2 miles (3 km) from the city centre.

Plan your Cayo Guillermo holiday with Expedia

  • Our 2020 bundled deals are currently unavailable, but you can now book our 2021 holiday packages deals. Buy your accommodation, flight or car together and get extra savings on your next trip!
  • We have selected for you amazing deals on incredible hotels in Cayo Guillermo. Have a look simply by using the search bar above.
  • Most hotels come with free cancellation, because we believe that flexibility matters now more than ever!

For more information, visit our COVID-19 information page
Start browsing now!

*Some hotels require you to cancel at least 24-48 hours before check-in.

Frequently asked questions

How much does a Cayo Guillermo holiday package cost?
Starting from as low as , you can customize your Cayo Guillermo holiday package. Simply bundle hotels, flights and rental cars and we’ll reward you with discounts.
If I'm not able to travel, can I cancel my Cayo Guillermo holiday package?
Because we understand life is full of surprises, the answer is yes. To learn more, visit our Customer Service Portal. But generally speaking, if you’ve booked your package in the last 24 hours, you may be able to cancel or change it for no charge. Your hotel, airline or car rental company may impose a fee if your booking is older than that.
How do I get a cheap travel package to Cayo Guillermo?
Browse and book everything in the one place with our Cayo Guillermo holiday packages. We have deals on hotels, flights and more that’ll keep your bank account happy and your adventurous spirit full. Actually, you can save up to 15% just for bundling your bookings. And, with more than 400 airlines and 321,000 hotels around the globe to pick from, you have countless opportunities to mix and match as you please.
When is the best time of year to visit Cayo Guillermo?
The best time to travel to Cayo Guillermo comes down to personal preference. If you’re holidaying on a budget, you might want to avoid , which is considered to be the most expensive time of year. is usually when you’ll score the best deals. To experience the atmosphere of peak season, pack your bags for . are the quietest months to visit and a smart idea if you want to get away from the crowds.
How far in advance should I book my Cayo Guillermo holiday?
Savvy travellers always book early. Air carriers typically release flight tickets up to 12 months in advance, and this is your chance to score some of the lowest prices. Boss just told you to take some holiday time in a few weeks? Don’t fret. Expedia are never short on fantastic bargains to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Cayo Guillermo travel package include?
Expedia has all you need to arrange your Cayo Guillermo escape, but how your package is structured is your choice. Choose from a combination of flights, rental cars and hotels. After some activities to keep you on the move? Once you’ve made your booking, you can add them on too. Whatever your budget or style, there’s a package deal to match your needs.
What should I know before booking a Cayo Guillermo travel package?
Booking all the parts of your getaway together is one of the easiest ways to save. Bundle your airfares, rental cars and hotels into a convenient package. But you’re not limited to hotels. Expedia offers all sorts of properties, including holiday rentals such as mountain cabins and city apartments. Your choices are almost endless!
Does Expedia offer Book Now, Pay Later Cayo Guillermo holiday packages?
Pay the full cost of your holiday package when you book or split it into numerous installments — the choice is yours. Each traveller has their own set of financial circumstances. That’s why Expedia has teamed up with online lender Affirm to provide a Book Now, Pay Later solution for all package bookings.
Can I choose my airline with a Cayo Guillermo Expedia holiday package?
Definitely. Expedia has more than 550 airline partners to pick from across the world. With such a big range of choice, finding the perfect carrier to fly you to Cayo Guillermo will be a snap.