Title: The 10 Best 4 Star Hotels in South San Francisco - 2026 Updated Prices | Expedia.co.uk [South San Francisco Travel Guide](https://expedia.co.uk/South-San-Francisco.dx6773)[Hotels in South San Francisco](https://expedia.co.uk/South-San-Francisco-Hotels.d6773.Travel-Guide-Hotels)[Holiday Rentals in South San Francisco](https://expedia.co.uk/South-San-Francisco-Holiday-Rentals.d6773.Travel-Guide-HolidayRentals)[Flights to South San Francisco](https://expedia.co.uk/Cheap-Flights-To-South-San-Francisco.d6773.Travel-Guide-Flights)[Things to do in South San Francisco](https://expedia.co.uk/Things-To-Do-In-South-San-Francisco.d6773.Travel-Guide-Activities)[South San Francisco Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-San-Francisco.d6773.Car-Hire-Guide)[South San Francisco Holidays](https://expedia.co.uk/South-San-Francisco.d6773.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/6773/149d3826-ba90-46a7-bd10-00098a5921a1.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀 ![](https://images.trvl-media.com/place/6773/149d3826-ba90-46a7-bd10-00098a5921a1.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South San Francisco 4 Star Hotels Tonight [31 Mar - 1 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6773&startDate=2026-03-31&endDate=2026-04-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [1 Apr - 2 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6773&startDate=2026-04-01&endDate=2026-04-02&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6773&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6773&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South San Francisco 4-star hotels ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/cd59b3af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/fb03adf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/4e4ef19d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Fisherman's Wharf [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) Fisherman's Wharf 9.0/10 Wonderful (7,395 reviews) "Loved location, kind staff, parking, clean and comfy rooms plus a decent breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra £154 includes taxes & fees 14 Apr - 15 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/22a22cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/b954d76f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/1e7669a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Hotel Berkeley Marina [](https://www.expedia.co.uk/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) Berkeley Marina 8.2/10 Very good (4,427 reviews) "I love staying here. The location is beautiful and serene while the rooms are well taken care of. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marisa £113 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![Breakfast, lunch, dinner served; Asian cuisine ](https://images.trvl-media.com/lodging/34000000/33470000/33462100/33462010/e6f59e08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/34000000/33470000/33462100/33462010/a46cfa6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/34000000/33470000/33462100/33462010/3cb59227.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33470000/33462100/33462010/6f16df27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hyatt at SFO [](https://www.expedia.co.uk/San-Francisco-Hotels-Grand-Hyatt-At-SFO.h33462010.Hotel-Information) San Francisco 9.8/10 Exceptional (1,537 reviews) "Convenient location to SFO and restaurants nearby" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheng Yi £245 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-Grand-Hyatt-At-SFO.h33462010.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/10000/900/828/efc155d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/900/828/6c45dc3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/1000000/10000/900/828/550e44fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/828/8f88044a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton San Francisco Airport [](https://www.expedia.co.uk/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-Airport.h828.Hotel-Information) Bayfront 8.6/10 Excellent (1,496 reviews) "Very nice hotel, clean, Starbucks onsite, and great breakfast choices." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fritz Lou £96 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-Airport.h828.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/96ca1121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed, Balcony, Bay View | Living area | 55-inch LCD TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/a2b2e8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/0df576f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Francisco Financial District [](https://www.expedia.co.uk/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) Downtown San Francisco 8.8/10 Excellent (2,562 reviews) "Amazing location and staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Odirlei £114 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed, Kitchenette (with Terrace) | 1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/acf84b9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/4c4de4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed, Kitchenette (with Terrace) | 1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/8e808fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Quarters Hotel in San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (3,027 reviews) "Very helpful staff, plus we got an early check in! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie £106 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/4ad0cb45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/968e9a2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Balcony | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/450add06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Balcony, Bay View (High Floor) | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/a384e85f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information) Downtown San Francisco 9.2/10 Wonderful (2,145 reviews) "Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert Charles £213 includes taxes & fees 3 Apr - 4 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/9100/9019/96aab860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down duvets, Select Comfort beds](https://images.trvl-media.com/lodging/1000000/10000/9100/9019/2f01b1f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/9100/9019/e67304df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/10000/9100/9019/8b121348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oakland Marriott City Center [](https://www.expedia.co.uk/Oakland-Hotels-Oakland-Marriott-City-Center.h9019.Hotel-Information) Downtown Oakland 9.0/10 Wonderful (1,005 reviews) "Great stay for kids and adults. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jasmine £99 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Oakland-Hotels-Oakland-Marriott-City-Center.h9019.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5900/5883/dc5cca5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/10000/5900/5883/528ae623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/5900/5883/22ceb761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5900/5883/145aa21d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hyatt San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Grand-Hyatt-San-Francisco-Union-Square.h5883.Hotel-Information) Union Square 9.0/10 Wonderful (1,012 reviews) "Their breakfast was really good and the staff was nice and attentive. The areas were clean and up to date and if I needed anything the staff was very helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £173 includes taxes & fees 25 Apr - 26 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-Grand-Hyatt-San-Francisco-Union-Square.h5883.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/d9a28cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/e6503d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/6a4c1f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/fcb07f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zoe Fisherman's Wharf [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information) Fisherman's Wharf 9.2/10 Wonderful (1,789 reviews) "Great location, friendly staff, nice rooms. " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Clyden £136 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/173b8dfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/7bc06dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/4817709a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/19abbe84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zephyr San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) Fisherman's Wharf 8.6/10 Excellent (2,495 reviews) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramona £160 includes taxes & fees 29 Apr - 30 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/487/128a46e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/487/f6105ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/500/487/81433b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/500/487/111baa3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton San Francisco South Airport Blvd [](https://www.expedia.co.uk/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-South-Airport-Blvd.h487.Hotel-Information) South San Francisco 8.4/10 Very good (2,201 reviews) "clean and nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kathleen £109 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-South-Airport-Blvd.h487.Hotel-Information) ![55-inch TV with digital channels, pay films](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/9e51cedf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Private Apartment) | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/174738f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Private Apartment) | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/7626c0a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, rainfall showerhead, free toiletries](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/40e87352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clift Royal Sonesta San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Clift-Royal-Sonesta-San-Francisco.h21073.Hotel-Information) Union Square 9.2/10 Wonderful (1,410 reviews) "Very nice and clean rooms, staff was incredible and the overall vibe and location was perfect. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Seth S. £163 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Clift-Royal-Sonesta-San-Francisco.h21073.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/a6ba3784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/2711ab7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/105e4279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/b8c723b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marker Union Square San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) Union Square 9.2/10 Wonderful (1,202 reviews) "great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorena £153 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1110/0fdb0ab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/1200/1110/a452632b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1200/1110/2c399818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/1200/1110/95039663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Triton [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Triton.h1110.Hotel-Information) Union Square 8.8/10 Excellent (1,000 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chaka £134 includes taxes & fees 17 Apr - 18 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Triton.h1110.Hotel-Information) ![Coffee shop](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/7985eb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/3bc0e86d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/f72650f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/dda8fd11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### LUMA Hotel San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) Downtown San Francisco 9.6/10 Exceptional (2,434 reviews) "Excellent hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexis £196 includes taxes & fees 18 Apr - 19 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/b53af55a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/308976ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/01ffa11d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/c1d68595.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Nikko San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Nikko-San-Francisco.h23406.Hotel-Information) Union Square 9.4/10 Exceptional (2,819 reviews) "The hotel was clean and the staff was incredible. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jake £194 includes taxes & fees 1 May - 2 May [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Nikko-San-Francisco.h23406.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/440000/438200/438136/169545aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/440000/438200/438136/fbde6e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/438200/438136/dfcb3ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/440000/438200/438136/680962da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Shattuck Plaza [](https://www.expedia.co.uk/Oakland-Hotels-Hotel-Shattuck-Plaza.h438136.Hotel-Information) Downtown Berkeley 9.0/10 Wonderful (1,147 reviews) "Nice historic hotel. I'd stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £148 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Oakland-Hotels-Hotel-Shattuck-Plaza.h438136.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/23900/23838/626a04ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/23900/23838/a180874f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/30000/23900/23838/3ac5d1b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![48-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/1000000/30000/23900/23838/3619f266.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Francisco Airport Marriott Waterfront [](https://www.expedia.co.uk/San-Francisco-Hotels-San-Francisco-Airport-Marriott-Waterfront.h23838.Hotel-Information) Ingold - Milldale 8.6/10 Excellent (1,144 reviews) "Excellent facilities and staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £122 includes taxes & fees 1 May - 2 May [](https://www.expedia.co.uk/San-Francisco-Hotels-San-Francisco-Airport-Marriott-Waterfront.h23838.Hotel-Information) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/3d33e0c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/af41aba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/dab2d28e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/99dd32f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin St. Francis San Francisco on Union Square [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Westin-St-Francis-San-Francisco-On-Union-Square.h26760.Hotel-Information) Union Square 8.8/10 Excellent (2,383 reviews) "Best place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Duane £199 includes taxes & fees 25 Apr - 26 Apr [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Westin-St-Francis-San-Francisco-On-Union-Square.h26760.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-South-San-Francisco-Hotels.s40-0-d6773.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-South-San-Francisco-Hotels.s40-0-d6773.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in South San Francisco. ![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairmont San Francisco 950 Mason Street Atop Nob Hill San Francisco CA £257 6 Apr - 7 Apr includes taxes & fees 9/10 Wonderful! (1,502 reviews) [](https://expedia.co.uk/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ![Palace Hotel, a Luxury Collection Hotel, San Francisco](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/w4000h2663x0y0-df4f3756_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Palace Hotel, a Luxury Collection Hotel, San Francisco 2 New Montgomery St San Francisco CA £292 24 Apr - 25 Apr includes taxes & fees 9.2/10 Wonderful! (1,004 reviews) [](https://expedia.co.uk/San-Francisco-Hotels-Palace-Hotel.h27274.Hotel-Information) ![Taj Campton Place](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/4ff57257_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Taj Campton Place 340 Stockton St San Francisco CA £217 2 Apr - 3 Apr includes taxes & fees 9.2/10 Wonderful! (1,004 reviews) [](https://expedia.co.uk/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) Still don't see what you're looking for? [See all properties in South San Francisco.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F04%2F2026&endDate=02%2F04%2F2026®ionId=6773&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F04%2F2026&endDate=02%2F04%2F2026®ionId=6773&star=40&star=40&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F04%2F2026&endDate=02%2F04%2F2026®ionId=6773&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F04%2F2026&endDate=02%2F04%2F2026®ionId=6773&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F04%2F2026&endDate=02%2F04%2F2026®ionId=6773&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F04%2F2026&endDate=02%2F04%2F2026®ionId=6773&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about South San Francisco Perched on the edge of San Francisco Bay, this family-friendly city boasts a surprising castle and stunning mountain views. Foodies flock to local restaurants, while thrill-seekers race go-karts at K1 Speed or tour the famous See's Sweets factory. [See all hotels in South San Francisco](https://www.expedia.co.uk/Hotel-Search?startDate=2026-04-14&endDate=2026-04-15&adults=2®ionId=6773) ![](https://images.trvl-media.com/place/6773/149d3826-ba90-46a7-bd10-00098a5921a1.jpg?impolicy=fcrop&w=300&h=400&p=1&q=high) Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀 ## Top South San Francisco Hotel Reviews ![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/75f20517_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "Excellent. Great choices of food." [](https://expedia.co.uk/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![The Marker Union Square San Francisco](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/a6ba3784_y.jpg) ### The Marker Union Square San Francisco 10/10 Excellent "All around great hotel. " [](https://expedia.co.uk/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) ![Hotel Zephyr San Francisco](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/173b8dfb_y.jpg) ### Hotel Zephyr San Francisco 6/10 Okay "Good location, room was tired" [](https://expedia.co.uk/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) ![DoubleTree by Hilton San Francisco South Airport Blvd](https://images.trvl-media.com/lodging/1000000/10000/500/487/128a46e3_y.jpg) ### DoubleTree by Hilton San Francisco South Airport Blvd 10/10 Excellent "Nice" [](https://expedia.co.uk/San-Francisco-Hotels-DoubleTree-By-Hilton-San-Francisco-South-Airport-Blvd.h487.Hotel-Information) ![Hilton San Francisco Union Square](https://images.trvl-media.com/lodging/1000000/30000/25700/25622/8fb5ec03_y.jpg) ### Hilton San Francisco Union Square 6/10 Okay "The restroom door handle was broken and we were not able to close and lock the door. Same for toilet paper handle. WiFi works only first day. " [](https://expedia.co.uk/San-Francisco-Hotels-Hilton-San-Francisco-Union-Square.h25622.Hotel-Information) ![DoubleTree by Hilton Hotel Berkeley Marina](https://images.trvl-media.com/lodging/1000000/30000/23800/23800/ba0da8d5_y.jpg) ### DoubleTree by Hilton Hotel Berkeley Marina 10/10 Excellent "It was great having park right next to hotel." [](https://expedia.co.uk/Oakland-Hotels-DoubleTree-By-Hilton-Hotel-Berkeley-Marina.h23800.Hotel-Information) ![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/96ca1121_y.jpg) ### Hilton San Francisco Financial District 2/10 Terrible "Tired and old property neglect of maintenance, upkeep ,functionality and quality of a Hilton standards one would expect " [](https://expedia.co.uk/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![Club Quarters Hotel in San Francisco](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/9fbb800a_y.jpg) ### Club Quarters Hotel in San Francisco 10/10 Excellent "What a wonderful clean hotel with friendly staff and perfect location. " [](https://expedia.co.uk/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ## Find out more about South San Francisco ## Frequently asked questions ### What are the best 4-star hotels in South San Francisco? ### How much does it cost to stay in a 4-star hotel in South San Francisco? > - Search for the lowest price from £217 ### What's the difference between 5-star and 4-star hotels in South San Francisco? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [1 Star Hotels in San Francisco ](https://www.expedia.co.uk/1Star-San-Francisco-Hotels.s10-0-d178305.Travel-Guide-Filter-Hotels) - [1 Star Hotels in Treasure Island ](https://www.expedia.co.uk/1Star-Treasure-Island-Hotels.s10-0-d506142.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Bay Area ](https://www.expedia.co.uk/2Star-Bay-Area-Hotels.s20-0-d6056043.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Downtown San Francisco ](https://www.expedia.co.uk/2Star-Downtown-San-Francisco-San-Francisco-Hotels.s20-n6151902-0.Travel-Guide-Filter-Hotels) - 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