South San Francisco Holidays from £921

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Your South San Francisco Holiday

Lock in a South San Francisco holiday package and get ready to experience the best of this lively city. Consider basing yourself in the neighbourhood of Sharp Park, which is great for families, nature and golfing. Make your trip to South San Francisco even more fun by including some sightseeing. San Francisco State University, Cow Palace and Pacifica State Beach are among the major attractions worth exploring. Browse Expedia's wide range of travel options and start organising your ideal holiday to South San Francisco now.

Top South San Francisco Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

Union Square
Save 100% on your flight
£921
per person
7 Nov - 14 Nov
found 7 hours ago
Return direct flight included
Birmingham (BHX) to San Francisco (SFO)
8.8/10 Excellent! (2,259 reviews)
The Grove Inn

The Grove Inn

Western Addition
£1,027
per person
5 Oct - 10 Oct
found 14 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
9.2/10 Wonderful! (729 reviews)
Lovely place, great location!

Reviewed on 28 Aug 2026

San Remo Hotel

San Remo Hotel

North Beach
£940
per person
12 Oct - 17 Oct
found 13 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
8.6/10 Excellent! (1,013 reviews)
The room was the size of a shoe box! and ours came complete with a window that faced back to the hallway :/ they were under construction so that started bright and early at 9am on a Saturday! not a bad price but be warned! She’s also haunted so just go for that experience LOL The room itself reminded me of being in alcatraz. Actually, they might’ve had more leg room from the wall and bed!

Reviewed on 27 Aug 2026

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

Fisherman's Wharf
Save 100% on your flight
£1,123
per person
23 Oct - 30 Oct
found 1 day ago
Return direct flight included
Birmingham (BHX) to San Francisco (SFO)
9/10 Wonderful! (7,632 reviews)
The room was very comfortable for 4 adults. I liked that the shower/toilet are was separate from the sink area. The breakfast was very good and well organized for seating. Lots of different items for different diets. The only thing I thought was not good was the price for a drink at the bar. A vodka tonic was $16! I don’t drink much so I just wanted a drink at the hotel by the fire and then head up to bed.

Reviewed on 30 Aug 2026

Geary Parkway Motel At Mine Hospitality

Geary Parkway Motel At Mine Hospitality

Richmond District
£1,197
per person
12 Oct - 17 Oct
found 13 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
9.8/10 Exceptional! (49 reviews)
Terrific remodeled motel in the Richmond district. Extremely helpful and attentive staff.

Reviewed on 29 Aug 2026

South San Francisco Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Francisco Intl. Airport (SFO)
Population
67,300
Max Temp Winter
16ºC
Max Temp Summer
21ºC
Top Sights
San Francisco Zoo, California Academy of Sciences and San Francisco Museum of Modern Art

Top hotels in South San Francisco

Park Pointe Hotel

Park Pointe Hotel

245 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
£58
31 Aug - 1 Sept
includes taxes & fees
5.8/10 (1,091 reviews)
"DO NOT USE THIS PLACE!!"

Reviewed on 29 Aug 2026

Park Pointe Hotel
Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel

380 S Airport Boulevard South San Francisco CA
Fully refundableReserve now, pay when you stay
£98
6 Sept - 7 Sept
includes taxes & fees
Best Western Plus Grosvenor Airport Hotel
Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point

250 Gateway Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
£127
6 Sept - 7 Sept
includes taxes & fees
Embassy Suites by Hilton San Francisco Airport Oyster Point
See all 4,512 properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular South San Francisco attractions

San Bruno Point Park

7.8/10 (451 reviews)
Point San Bruno Park offers panoramic views of San Francisco Bay and close-up aircraft sightings from nearby SFO. Stroll the waterfront trails and find a peaceful picnic spot away from the city's bustle.
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South San Francisco Convention Center

7.8/10 (668 reviews)
The South San Francisco Conference Centre offers versatile meeting spaces with modern amenities near SFO airport. Business travellers appreciate its convenient location and comprehensive event services.
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San Francisco Baking Institute

7.6/10 (423 reviews)
Explore the campus of San Francisco Baking Institute as part of your travels around South San Francisco. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.
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See's Candies

8.0/10 (474 reviews)
This American-made chocolate factory store welcomes visitors with the intoxicating aroma of fresh confections. Customise your own box of premium sweets and savour the complimentary sample that greets every guest.
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K1 Speed San Francisco

7.6/10 (330 reviews)
Race electric go-karts at top speeds on K1 Speed's professionally designed indoor track. For the ultimate experience, arrive on weekday afternoons when the track is less crowded.
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South San Francisco Hillside Sign

You can find out about the history of South San Francisco with a visit to South San Francisco Hillside Sign.
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Sign Hill Park

Explore the great outdoors at Sign Hill Park, a lovely green space in South San Francisco. Visit the shops and top-notch restaurants in this family-friendly area.
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What to do in South San Francisco

Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

£72
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

£36
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

£43
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
See all activities in South San Francisco

Frequently asked questions

Why should I book my South San Francisco holiday with Expedia?
Choose Expedia to arrange your next big adventure simply and all in one place. Our top tip for bagging a fabulous deal on a South San Francisco retreat? Bundle your accommodation, flights and/or car hire into a package holiday. Then throw in some awesome tours and activities. Many bookings also include flexible cancellation policies, so there's no need to worry if you have to switch up your travel agenda. Round-the-clock help with making tweaks to your trip is available via our Customer Service Portal link.
When is the best time of year to holiday in South San Francisco?
March, April and May are the busiest months in South San Francisco, while February, October and December are generally a lot quieter. With daytime average temperatures of 11ºC, January is the coolest month in South San Francisco. The warmest month is August, when you can experience average temperatures of 17ºC throughout the day. Whatever the weather conditions, you'll discover plenty to keep you entertained here.
What are the top hotels for my holiday in South San Francisco?
If you're planning to stay in the Downtown South San Francisco neighbourhood, Best Western Plus Grosvenor Airport Hotel and Travelodge by Wyndham San Francisco Airport North are great options. The East Side is also a well-known South San Francisco area. We recommend Hotel Focus SFO or La Quinta Inn & Suites by Wyndham San Francisco Airport N if you choose this end of town.
How do I get a cheap holiday to South San Francisco?
Secure flights that fit your schedule, add a hotel room to your booking and watch the savings rack up with a South San Francisco holiday. It's as easy as that! From hotels and flights to hire cars and activities, Expedia makes travelling cheaply a cinch. And with over 400 airlines and 321,000 properties globally to pick from, you won't be short of choice. Learn more about how you can save money on your next holiday when you bundle your flight and hotel bookings with Expedia.
What should I do on my South San Francisco holiday?
There are lots of things to keep you busy while enjoying a holiday in South San Francisco. San Francisco State University, University of San Francisco, University of California, San Francisco and Oracle Park are among this destination's most popular attractions.
What is the best area to stay in when on holiday in South San Francisco?
There's so much to see in South San Francisco, so spend your nights close to its top sights and allow yourself more time sightseeing. Sees Candies is one place to put on your itinerary.
Do I need a visa for my South San Francisco holiday?
Official government websites have all the information you need on visa requirements, application procedures and any necessary documentation. Your nationality and the reason for your visit, whether it be for holidays or business, will determine if you'll need a visa for South San Francisco. Also be sure that your passport is up to date and has a minimum of six months validity remaining beyond your planned date of return. Do all your travel planning well in advance to avoid any nasty last-minute surprises.
What should I wear on my South San Francisco holiday?
Do a little research into the sorts of things people in South San Francisco wear, and maybe even browse style blogs for some fashion inspiration. Whatever your look, try to create a versatile wardrobe with pieces that work for your destination and showcase your unique sense of style. Pack with confidence by looking up the forecast in South San Francisco. August brings the warmest temperatures, with daily averages of 17ºC, while January days average 11ºC, making it the coolest time of year.
What does an Expedia South San Francisco holiday include?
Choose from a combination of hire cars, hotels and flights. Once you've made your booking, add some tours and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to creating your perfect South San Francisco getaway. Discover a wide range of property types and select one that suits the size of your group. The most sought-after rentals here are private holiday homes and apartments. With Expedia, you can easily tailor-make your South San Francisco escape any way you want.
Does Expedia offer Book Now, Pay Later South San Francisco holidays?
Yes. Expedia has partnered with online lender Klarna to help you conveniently pay for your trip in manageable instalments. Simply pick the payment plan that suits best during checkout and take away the stress of budgeting for your trip. Be sure to bundle your accommodation, car hire and flights with Expedia to get the biggest bang for your holiday buck. Check out our flexible payment options below:
  • Pay monthly holidays: If paying bite-sized amounts each month is what works best for you, Klarna offers just that! Paying in convenient monthly instalments will make your holiday dreams possible.
  • No-deposit holidays: When you want to grab an amazing deal but don't have the full amount yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to secure your getaway.
Can I choose my airline with a South San Francisco Expedia holiday?
Yes — and it's simple too. Expedia has access to more than 400 partner airlines globally. Our holiday packages give you the freedom to pick from available flights, hotels and activities that fit your needs.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.