South San Francisco Holidays from £786

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Your South San Francisco Holiday

Lock in a South San Francisco holiday package and get ready to experience the best of this lively city. Consider basing yourself in the neighbourhood of Sharp Park, which is great for families, nature and golfing. Make your trip to South San Francisco even more fun by including some sightseeing. San Francisco State University, Cow Palace and Pacifica State Beach are among the major attractions worth exploring. Browse Expedia's wide range of travel options and start organising your ideal holiday to South San Francisco now.

Top South San Francisco Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Fitzgerald Hotel

Fitzgerald Hotel

3 out of 5
Union Square
Save 100% on your flight
per person
14 Sept - 19 Sept
found 1 day ago
Return flight included
London (LHR) to San Francisco (SFO)
7.8/10 Good! (410 reviews)
If you want budget accommodation this is for you. Nothing like the photos on Expedia. But it's still ok accommodation. Make sure you pack ear plugs, as the walls a very thin.

Reviewed on 10 Jun 2025

The Grove Inn

The Grove Inn

3 out of 5
Western Addition
Save 100% on your flight
per person
14 Sept - 19 Sept
found 1 day ago
Return flight included
London (LHR) to San Francisco (SFO)
9.2/10 Wonderful! (641 reviews)
The property is in a quiet neighborhood and the staff are very responsive and proactive bin terms of communication. The property is an old, beautiful home, but the room was updated and modern in terms of comfort and convenience. Nice bed and nice linens made everything very comfortable.

Reviewed on 3 Jul 2025

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
per person
20 Aug - 25 Aug
found 24 hours ago
Return direct flight included
London (LON) to San Francisco (SFO)
9.2/10 Wonderful! (414 reviews)
The check in was convenient and quick. Very informative as well.

Reviewed on 1 Jul 2025

The Marker Union Square San Francisco

The Marker Union Square San Francisco

4 out of 5
Union Square
Save 100% on your flight
per person
14 Sept - 19 Sept
found 1 day ago
Return flight included
London (LHR) to San Francisco (SFO)
8.8/10 Excellent! (1,012 reviews)
Everyone was super nice and the property was definitely worth the price

Reviewed on 1 Jul 2025

Hotel Zelos San Francisco

Hotel Zelos San Francisco

4 out of 5
Downtown San Francisco
Save 100% on your flight
per person
14 Sept - 19 Sept
found 1 day ago
Return flight included
London (LHR) to San Francisco (SFO)
9/10 Wonderful! (1,006 reviews)
Awesome room and staff

Reviewed on 8 Jul 2025

Where to stay in South San Francisco

Find the best South San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about South San Francisco
Default Image

The East Side

2 out of top 10 points of interest in this area
3.5/5(19 area reviews)

While visiting The East Side, you might make a stop by sights like San Francisco Bay and San Bruno Point Park.

Find hotels in The East Side

South San Francisco Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Francisco Intl. Airport (SFO)
Population
67,300
Max Temp Winter
16ºC
Max Temp Summer
21ºC
Top Sights
San Francisco Zoo, California Academy of Sciences and San Francisco Museum of Modern Art

Top hotels in South San Francisco

Best Western Plus Grosvenor Airport Hotel
Best Western Plus Grosvenor Airport Hotel
3 out of 5
380 S Airport Boulevard, South San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is £90 per night from 25 Jul to 26 Jul
£90
25 Jul - 26 Jul
includes taxes & fees
8.2/10 Very Good! (1,482 reviews)
"Convince location, close to airport. Old, small room. Great breakfast. Old , small room."

Reviewed on 7 Jul 2025

Best Western Plus Grosvenor Airport Hotel
Sonesta Select San Francisco Airport Oyster Point Waterfront
Sonesta Select San Francisco Airport Oyster Point Waterfront
3 out of 5
1300 Veterans Blvd, South San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is £100 per night from 13 Jul to 14 Jul
£100
13 Jul - 14 Jul
includes taxes & fees
8.4/10 Very Good! (1,570 reviews)
"I loved everything."

Reviewed on 7 Jul 2025

Sonesta Select San Francisco Airport Oyster Point Waterfront
DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport Blvd
4 out of 5
275 S Airport Blvd, South San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is £107 per night from 18 Jul to 19 Jul
£107
18 Jul - 19 Jul
includes taxes & fees
8.4/10 Very Good! (1,724 reviews)
"Great stay!"

Reviewed on 6 Jul 2025

DoubleTree by Hilton San Francisco South Airport Blvd
See all 4,991 properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Holidays

All Inclusive Holidays

Beach Holidays

Beach Holidays

Family Friendly Holidays

Family Friendly Holidays

Popular places to visit

Golden Gate Park featuring a garden and flowers

Golden Gate Park

4.5/5(323 reviews)

This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

Golden Gate Park
Pier 39 featuring street scenes, a city and signage

Pier 39

4/5(364 reviews)

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Pier 39
Golden Gate Bridge featuring a suspension bridge or treetop walkway, night scenes and general coastal views

Golden Gate Bridge

4.5/5(362 reviews)

Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Golden Gate Bridge

What to do in South San Francisco

Golden Gate Bridge at night

San Francisco Night Tour

£39
per adult
76% of travellers recommend
San Francisco Night Tour
San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat

San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat

£28
per adult
94% of travellers recommend
San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat
Alcatraz San Francisco Bay Cruise with Night Option

Alcatraz San Francisco Bay Cruise with Night Option

£103
per adult
92% of travellers recommend
Alcatraz San Francisco Bay Cruise with Night Option
See all activities in South San Francisco

Frequently asked questions

Why should I book my South San Francisco holiday with Expedia?
Choose Expedia to arrange your next big adventure simply and all in one place. Our top tip for bagging a fabulous deal on a South San Francisco retreat? Bundle your accommodation, flights and/or car hire into a package holiday. Then throw in some awesome tours and activities. Many bookings also include flexible cancellation policies, so there's no need to worry if you have to switch up your travel agenda. Round-the-clock help with making tweaks to your trip is available via our Customer Service Portal link.
When is the best time of year to holiday in South San Francisco?
March, April and May are the busiest months in South San Francisco, while February, October and December are generally a lot quieter. With daytime average temperatures of 11ºC, January is the coolest month in South San Francisco. The warmest month is August, when you can experience average temperatures of 17ºC throughout the day. Whatever the weather conditions, you'll discover plenty to keep you entertained here.
What are the top hotels for my holiday in South San Francisco?
If you're planning to stay in the Downtown South San Francisco neighbourhood, Best Western Plus Grosvenor Airport Hotel and Travelodge by Wyndham San Francisco Airport North are great options. The East Side is also a well-known South San Francisco area. We recommend Hotel Focus SFO or La Quinta Inn & Suites by Wyndham San Francisco Airport N if you choose this end of town.
How do I get a cheap holiday to South San Francisco?
Secure flights that fit your schedule, add a hotel room to your booking and watch the savings rack up with a South San Francisco holiday. It's as easy as that! From hotels and flights to hire cars and activities, Expedia makes travelling cheaply a cinch. And with over 400 airlines and 321,000 properties globally to pick from, you won't be short of choice. Learn more about how you can save money on your next holiday when you bundle your flight and hotel bookings with Expedia.
What should I do on my South San Francisco holiday?
There are lots of things to keep you busy while enjoying a holiday in South San Francisco. San Francisco State University, University of San Francisco, University of California, San Francisco and Oracle Park are among this destination's most popular attractions.
What is the best area to stay in when on holiday in South San Francisco?
There's so much to see in South San Francisco, so spend your nights close to its top sights and allow yourself more time sightseeing. Sees Candies is one place to put on your itinerary.
Do I need a visa for my South San Francisco holiday?
Official government websites have all the information you need on visa requirements, application procedures and any necessary documentation. Your nationality and the reason for your visit, whether it be for holidays or business, will determine if you'll need a visa for South San Francisco. Also be sure that your passport is up to date and has a minimum of six months validity remaining beyond your planned date of return. Do all your travel planning well in advance to avoid any nasty last-minute surprises.
What should I wear on my South San Francisco holiday?
Do a little research into the sorts of things people in South San Francisco wear, and maybe even browse style blogs for some fashion inspiration. Whatever your look, try to create a versatile wardrobe with pieces that work for your destination and showcase your unique sense of style. Pack with confidence by looking up the forecast in South San Francisco. August brings the warmest temperatures, with daily averages of 17ºC, while January days average 11ºC, making it the coolest time of year.
What does an Expedia South San Francisco holiday include?
Choose from a combination of hire cars, hotels and flights. Once you've made your booking, add some tours and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to creating your perfect South San Francisco getaway. Discover a wide range of property types and select one that suits the size of your group. The most sought-after rentals here are private holiday homes and apartments. With Expedia, you can easily tailor-make your South San Francisco escape any way you want.
Does Expedia offer Book Now, Pay Later South San Francisco holidays?
Yes. Expedia has partnered with online lender Klarna to help you conveniently pay for your trip in manageable instalments. Simply pick the payment plan that suits best during checkout and take away the stress of budgeting for your trip. Be sure to bundle your accommodation, car hire and flights with Expedia to get the biggest bang for your holiday buck. Check out our flexible payment options below:

  • Pay monthly holidays: If paying bite-sized amounts each month is what works best for you, Klarna offers just that! Paying in convenient monthly instalments will make your holiday dreams possible.
  • No-deposit holidays: When you want to grab an amazing deal but don't have the full amount yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to secure your getaway.

Can I choose my airline with a South San Francisco Expedia holiday?
Yes --- and it's simple too. Expedia has access to more than 400 partner airlines globally. Our holiday packages give you the freedom to pick from available flights, hotels and activities that fit your needs.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.