South San Francisco Holidays from £868

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Your South San Francisco Holiday

Lock in a South San Francisco holiday package and get ready to experience the best of this lively city. Consider basing yourself in the neighbourhood of Sharp Park, which is great for families, nature and golfing. Make your trip to South San Francisco even more fun by including some sightseeing. San Francisco State University, Cow Palace and Pacifica State Beach are among the major attractions worth exploring. Browse Expedia's wide range of travel options and start organising your ideal holiday to South San Francisco now.

Top South San Francisco Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

4.5 out of 5
Union Square
Price was £1,106, price is now £868 per person
£868
per person
1 Oct - 4 Oct
found 1 day ago
Return direct flight included
Manchester (MAN) to San Francisco (SFO)
8.8/10 Excellent! (2,322 reviews)
The classic San Francisco! Where should I begin?? Everything was so immaculate! Service flawless; Rooms were perfectly clean and beds were perfectly comfortable. Of course the hotel is old but boy they have maintained it so well ! Its right at Union Square so you already won in terms of location! Its central to everything and you can pick and choose any of the public transportation modes that SFO provides right outside of the hotel. We loved it and will definitely come back again.

Reviewed on 13 Jul 2026

Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square

5 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was £4,114, price is now £2,776 per person
£2,776
per person
7 Sept - 14 Sept
found 23 hours ago
Return flight included
London (LON) to San Francisco (SFO)
9.4/10 Exceptional! (406 reviews)
Parking garage is small overhead. Our truck did not fit and we were rold ee needed to come move it. Staff didnt have any good recommendatiins. The paid lot they tell you to go to is not secure and has a recird of break ins. Had to find our own place. Ended up paying to park at a hotel a half mile down street. This needs to be fixed. Probobly wont come again until so.

Reviewed on 14 Jul 2026

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Price was £1,084, price is now £869 per person
£869
per person
1 Oct - 4 Oct
found 1 day ago
Return direct flight included
Manchester (MAN) to San Francisco (SFO)
9/10 Wonderful! (7,526 reviews)
The location was nice to be able to walk to Fishermans Wharf and the Pier each day. The lobby and co-use areas are very nice. Breakfast was great and efficient. Some shady characters outside every now and then. The room was disappointing. Had a musty smell, smaller than expected. Paid for a superior room but no view or anything special about it.

Reviewed on 16 Jul 2026

DoubleTree by Hilton San Francisco Airport North Bayfront

DoubleTree by Hilton San Francisco Airport North Bayfront

4 out of 5
Price was £1,381, price is now £1,118 per person
£1,118
per person
18 Sept - 25 Sept
found 4 hours ago
Return flight included
Manchester (MAN) to San Francisco (SFO)
8.2/10 Very good! (1,599 reviews)

Motel 6 San Francisco, CA – Great Highway

Motel 6 San Francisco, CA – Great Highway

2 out of 5
Golden Gate
Price was £1,073, price is now £876 per person
£876
per person
18 Sept - 25 Sept
found 4 hours ago
Return flight included
Manchester (MAN) to San Francisco (SFO)
6.8/10 (655 reviews)
Room was very old but roomy. Air conditioner was very dusty. Sink in bathroom was all cracked. The guests in the next room were loud and fighting. I checked in at midnight and kept ringing the doorbell until the guy finally woke up to check me in. Just ok.

Reviewed on 15 Jul 2026

South San Francisco Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Francisco Intl. Airport (SFO)
Population
67,300
Max Temp Winter
16ºC
Max Temp Summer
21ºC
Top Sights
San Francisco Zoo, California Academy of Sciences and San Francisco Museum of Modern Art

Top hotels in South San Francisco

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

2 out of 5
326 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is £59 per night from 28 Jul to 29 Jul
£59
28 Jul - 29 Jul
includes taxes & fees
6/10 (3,853 reviews)
"The airport shuttle ran on a tight schedule that was listed in the lobby and it was timely. The staff was helpful in answering questions. The room, however, was not clean, smelled of urine (likely from an animal), was out of toilet paper upon arrival, and generally not upkept."

Reviewed on 15 Jul 2026

Travelodge by Wyndham San Francisco Airport North
DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd

4 out of 5
275 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is £113 per night from 9 Aug to 10 Aug
£113
9 Aug - 10 Aug
includes taxes & fees
8.4/10 Very good! (2,379 reviews)
"Clean room."

Reviewed on 16 Jul 2026

DoubleTree by Hilton San Francisco South Airport Blvd
Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel

3 out of 5
380 S Airport Boulevard South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is £96 per night from 19 Jul to 20 Jul
£96
19 Jul - 20 Jul
includes taxes & fees
Best Western Plus Grosvenor Airport Hotel
See all 4,598 properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Stay near popular South San Francisco attractions

San Bruno Point Park

7.8/10 (451 reviews)
Point San Bruno Park offers panoramic views of San Francisco Bay and close-up aircraft sightings from nearby SFO. Stroll the waterfront trails and find a peaceful picnic spot away from the city's bustle.
See properties

What to do in South San Francisco

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

£41
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

£82
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

£44
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
See all activities in South San Francisco

Frequently asked questions

Why should I book my South San Francisco holiday with Expedia?
Choose Expedia to arrange your next big adventure simply and all in one place. Our top tip for bagging a fabulous deal on a South San Francisco retreat? Bundle your accommodation, flights and/or car hire into a package holiday. Then throw in some awesome tours and activities. Many bookings also include flexible cancellation policies, so there's no need to worry if you have to switch up your travel agenda. Round-the-clock help with making tweaks to your trip is available via our Customer Service Portal link.
When is the best time of year to holiday in South San Francisco?
March, April and May are the busiest months in South San Francisco, while February, October and December are generally a lot quieter. With daytime average temperatures of 11ºC, January is the coolest month in South San Francisco. The warmest month is August, when you can experience average temperatures of 17ºC throughout the day. Whatever the weather conditions, you'll discover plenty to keep you entertained here.
What are the top hotels for my holiday in South San Francisco?
If you're planning to stay in the Downtown South San Francisco neighbourhood, Best Western Plus Grosvenor Airport Hotel and Travelodge by Wyndham San Francisco Airport North are great options. The East Side is also a well-known South San Francisco area. We recommend Hotel Focus SFO or La Quinta Inn & Suites by Wyndham San Francisco Airport N if you choose this end of town.
How do I get a cheap holiday to South San Francisco?
Secure flights that fit your schedule, add a hotel room to your booking and watch the savings rack up with a South San Francisco holiday. It's as easy as that! From hotels and flights to hire cars and activities, Expedia makes travelling cheaply a cinch. And with over 400 airlines and 321,000 properties globally to pick from, you won't be short of choice. Learn more about how you can save money on your next holiday when you bundle your flight and hotel bookings with Expedia.
What should I do on my South San Francisco holiday?
There are lots of things to keep you busy while enjoying a holiday in South San Francisco. San Francisco State University, University of San Francisco, University of California, San Francisco and Oracle Park are among this destination's most popular attractions.
What is the best area to stay in when on holiday in South San Francisco?
There's so much to see in South San Francisco, so spend your nights close to its top sights and allow yourself more time sightseeing. Sees Candies is one place to put on your itinerary.
Do I need a visa for my South San Francisco holiday?
Official government websites have all the information you need on visa requirements, application procedures and any necessary documentation. Your nationality and the reason for your visit, whether it be for holidays or business, will determine if you'll need a visa for South San Francisco. Also be sure that your passport is up to date and has a minimum of six months validity remaining beyond your planned date of return. Do all your travel planning well in advance to avoid any nasty last-minute surprises.
What should I wear on my South San Francisco holiday?
Do a little research into the sorts of things people in South San Francisco wear, and maybe even browse style blogs for some fashion inspiration. Whatever your look, try to create a versatile wardrobe with pieces that work for your destination and showcase your unique sense of style. Pack with confidence by looking up the forecast in South San Francisco. August brings the warmest temperatures, with daily averages of 17ºC, while January days average 11ºC, making it the coolest time of year.
What does an Expedia South San Francisco holiday include?
Choose from a combination of hire cars, hotels and flights. Once you've made your booking, add some tours and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to creating your perfect South San Francisco getaway. Discover a wide range of property types and select one that suits the size of your group. The most sought-after rentals here are private holiday homes and apartments. With Expedia, you can easily tailor-make your South San Francisco escape any way you want.
Does Expedia offer Book Now, Pay Later South San Francisco holidays?
Yes. Expedia has partnered with online lender Klarna to help you conveniently pay for your trip in manageable instalments. Simply pick the payment plan that suits best during checkout and take away the stress of budgeting for your trip. Be sure to bundle your accommodation, car hire and flights with Expedia to get the biggest bang for your holiday buck. Check out our flexible payment options below:

  • Pay monthly holidays: If paying bite-sized amounts each month is what works best for you, Klarna offers just that! Paying in convenient monthly instalments will make your holiday dreams possible.
  • No-deposit holidays: When you want to grab an amazing deal but don't have the full amount yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to secure your getaway.

Can I choose my airline with a South San Francisco Expedia holiday?
Yes — and it's simple too. Expedia has access to more than 400 partner airlines globally. Our holiday packages give you the freedom to pick from available flights, hotels and activities that fit your needs.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.